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18 results for "ferroptosis-inhibitors&view=expanded" in Products

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Ferrostatin 1

Catalog #: 5180
(1)
Citations (11)
Product Documents

Selective inhibitor of erastin induced ferroptosis

Chemical Name: Ethyl 3-amino-4-(cyclohexylamino)benzoate
Purity: ≥98%
Selective inhibitor of erastin induced ferroptosis

FSEN 1

Catalog #: 7941
Product Documents

Induces ferroptosis; inhibits FSP1

Chemical Name: 3-(4-Bromophenyl)-6-((4-(4-methoxyphenyl)piperazin-1-yl)methyl)thiazolo[2,3-c][1,2,4]triazole
Purity: ≥98%
Induces ferroptosis; inhibits FSP1

iFSP1

Catalog #: 7162
Product Documents

Ferroptosis suppressor protein 1 (FSP1) inhibitor; ferroptosis inducer

Chemical Name: 1-Amino-3-(4-methylphenyl)-pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile
Purity: ≥98%
Ferroptosis suppressor protein 1 (FSP1) inhibitor; ferroptosis inducer

Liproxstatin-1 hydrochloride

Catalog #: 6113
Citations (8)
Product Documents

Potent ferroptosis inhibitor

Chemical Name: N-[(3-Chlorophenyl)methyl]spiro[piperidine-4,2'(1'H)-quinoxalin]-3'-amine hydrochloride
Purity: ≥98%
Potent ferroptosis inhibitor

PD 146176

Catalog #: 2850
Citations (19)
Product Documents

Selective 15-lipoxygenase inhibitor

Chemical Name: 6,11-Dihydro[1]benzothiopyrano[4,3-b]indole
Purity: ≥98%
Selective 15-lipoxygenase inhibitor

Sulfasalazine

Catalog #: 4935
Citations (14)
Product Documents

Inhibitor of NF-κB activation; also inhibits SXC and folate transporter 1

Chemical Name: 5-[[4-(2-Pyridylsulfamoyl)phenyl]azo]salicylic acid
Purity: ≥97%
Inhibitor of NF-κB activation; also inhibits SXC and folate transporter 1

1R,3R-RSL3

Catalog #: 6687
Citations (1)
Product Documents

Negative control for 1S,3R-RSL3 (Cat. No. 6118)

Chemical Name: (1R,3R)-Methyl 2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1-[4-(methoxycarbonyl)phenyl]-1H-pyrido[3,4-b]indole-3-carboxylate
Purity: ≥98%
Negative control for 1S,3R-RSL3 (Cat. No. 6118)

1S,3R-RSL3

Catalog #: 6118
Citations (13)
Product Documents

Inhibits glutathione peroxidase (GPX4); induces ferroptosis

Chemical Name: (1S,3R)-Methyl 2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1-[4-(methoxycarbonyl)phenyl]-1H-pyrido[3,4-b]indole-3-carboxylate
Purity: ≥98%
Inhibits glutathione peroxidase (GPX4); induces ferroptosis

Simvastatin

Catalog #: 1965
(1)
Citations (35)
Product Documents

HMG-CoA reductase inhibitor

Chemical Name: (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyly-2,2-dimethyl butanoate
Purity: ≥98%
HMG-CoA reductase inhibitor

ML 210

Catalog #: 6429
Citations (6)
Product Documents

Selectively kills mutant HRAS-expressing cells; glutathione peroxidase inhibitor; induces ferroptosis

Chemical Name: [4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl](5-methyl-4-nitro-3-isoxazolyl)methanone
Purity: ≥98%
Selectively kills mutant HRAS-expressing cells; glutathione peroxidase inhibitor; induces ferroptosis
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