11 results for "Histamine H1 R Small Molecules and Peptides" in Products
Histamine H1 R Small Molecules and Peptides
Histamine H1R (HRH1) is a G-protein coupled 7-transmembrane putative glycoprotein that is implicated in the pathogenesis of asthma and is a major pharmaceutical target for antihistamines. It has been detected as a mixture of monomers and homodimers, with highest concentration in the placenta, followed by brain, lung (produced by airway smooth muscle, bronchial epithelium and macrophages) and other tissues.
Endogenous histamine receptor agonist
| Chemical Name: | 2-(4-Imidazolyl)ethylamine dihydrochloride |
Orally active, potent H1 antagonist; also KV11.1 (hERG) channel blocker
| Alternate Names: | Hismanal |
| Chemical Name: | 1-[(4-Fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]-4-piperidinyl]-1H-benzimidazol-2-amine |
| Purity: | ≥98% |
Potent 5-HT2 antagonist; also 5-HT3, H1 and α2 antagonist; antidepressant
| Alternate Names: | Org 3770,6-Azamianserin |
| Chemical Name: | 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine |
| Purity: | ≥98% |
H1 antagonist. Also KV11.1 (hERG) and Kir6 (KATP) channel blocker
| Chemical Name: | α-[4-(1,1-Dimethylethyl)phenyl]-4-(hydroxydiphenylmethyl)-1-piperidinebutanol |
| Purity: | ≥98% |
H1/ H2 agonist
| Alternate Names: | Histamine trifluoromethyl toluidide |
| Chemical Name: | 6-[2-(4-Imidazolyl)ethylamino]-N-(4-trifluoromethylphenyl)heptanecarboxamide dimaleate |
| Purity: | ≥99% |
H1 antagonist
| Chemical Name: | (2R)-2-[2-[(1R)-1-(4-Chlorophenylethoxy]ethyl]-1-methyl-2-pyrrolidine fumarate |
| Purity: | ≥98% |
H1 agonist
| Chemical Name: | 2-Pyridineethanamine dihydrochloride |
| Purity: | ≥99% |
H1 antagonist; ocular antiallergic agent
| Chemical Name: | (Z)-11-[3-(Dimethylamino)propylidene]-6,11-dihydro-dibenz[b,e]oxepin-2-acetic acid hydrochloride |
| Purity: | ≥98% |
H1 antagonist
| Alternate Names: | DPH |
| Chemical Name: | 2-Diphenylmethoxy-N,N-dimethylethanamine hydrochloride |
| Purity: | ≥98% |
Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent
| Chemical Name: | (3aR*,12bR*)-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole maleate |
| Purity: | ≥98% |
Human pregnane X receptor agonist; H1 antagonist
| Alternate Names: | Meclozine |
| Chemical Name: | 1-[(4-Chlorophenyl)phenylmethyl]4-[(3-methylphenyl)methyl]piperazine dihydrochloride |
| Purity: | ≥99% |
