Matrix metalloproteinase 7, also known as Matrilysin, is a zinc and calcium dependent endopeptidase that is expressed in epithelial cells of normal and diseased tissues. It can digest a wide range of extracellular matrix proteins including Collagens IV and X, Gelatin, Casein, Laminin, Aggrecan, Entactin, Elastin, and Versican. MMP-7 can activate other proteinases such as Plasminogen, MMP-1, MMP-2, and MMP-9. In addition, MMP-7 regulates the activation or shedding of alpha-Defensin, TNF-alpha, and Fas Ligand.
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Contains 4 membranes-2 spotted in duplicate with antibodies against 35 different proteases and 2 spotted in duplicate with antibodies against 32 different protease inhibitors