84 results for "p38 beta/MAPK11" in Products
p38 beta/MAPK11 Products
The p38 mitogen-activated protein kinases (p38 MAP kinases) are a family of four related Ser/Thr kinases responsive to pro-inflammatory cytokines and environmental stresses, including ionizing radiation, oxidative stress, and osmotic shock. Each family member, p38 alpha, p38 beta, p38 delta, and p38 gamma, is activated by dual Thr and Tyr phosphorylation within a Thr-Gly-Tyr motif residing in the kinase activation loop. For p38 beta, also known as p38-2, stress-activated protein kinase 2B (SAPK2B), and MAPK11, this dual phosphorylation occurs at Thr180/Tyr182.
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: p38 beta/MAPK11 Antibody [NB100-56446]](https://resources.rndsystems.com/images/products/p38-beta-MAPK11-Antibody-Western-Blot-NB100-56446-img0003.jpg "Western Blot: p38 beta/MAPK11 Antibody [NB100-56446]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: p38 beta/MAPK11 Antibody [NBP2-98810]](https://resources.rndsystems.com/images/products/p38-beta-MAPK11-Antibody-Western-Blot-NBP2-98810-img0004.jpg "Western Blot: p38 beta/MAPK11 Antibody [NBP2-98810]")
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #280071 |
| Applications: | ICC/IF |
| Reactivity: | Human |
| Applications: |
| Applications: | AC |
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #E13-Q |
| Applications: | WB, ELISA, ICC/IF, IP |
![Western Blot: p38 beta/MAPK11 Antibody (E13-Q) [NBP3-08206]](https://resources.rndsystems.com/images/products/p38-beta-MAPK11-Antibody-E13-Q-Western-Blot-NBP3-08206-img0001.jpg "Western Blot: p38 beta/MAPK11 Antibody (E13-Q) [NBP3-08206]")
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #1F9 |
| Applications: | WB, ELISA, Mycoplasma |
![Western Blot: p38 beta/MAPK11 Antibody (1F9) [H00005600-M03]](https://resources.rndsystems.com/images/products/p38-beta-MAPK11-Antibody-1F9-Western-Blot-H00005600-M03-img0004.jpg "Western Blot: p38 beta/MAPK11 Antibody (1F9) [H00005600-M03]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry: p38 beta/MAPK11 Antibody [NBP2-48826]](https://resources.rndsystems.com/images/products/p38-beta-MAPK11-Antibody-Immunohistochemistry-NBP2-48826-img0001.jpg "Immunohistochemistry: p38 beta/MAPK11 Antibody [NBP2-48826]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
![p38 beta/MAPK11 Antibody Immunocytochemistry/Immunofluorescence: p38 beta/MAPK11 Antibody [NBP3-25035]](https://resources.rndsystems.com/images/products/nbp3-25035_rabbit-p38-beta-mapk11-pab-1912202316104618.jpg "Immunocytochemistry/Immunofluorescence: p38 beta/MAPK11 Antibody [NBP3-25035]")
| Reactivity: | Human |
| Applications: | WB |
![Western Blot: p38 beta/MAPK11 Overexpression Lysate [NBL1-12870]](https://resources.rndsystems.com/images/products/MAPK11-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-12870-img0002.jpg "Western Blot: p38 beta/MAPK11 Overexpression Lysate [NBL1-12870]")
| Reactivity: | Human |
| Source: | E. coli |
| Applications: | PAGE |
![SDS-PAGE: Recombinant Human p38 beta/MAPK11 His Protein [NBP1-72538]](https://resources.rndsystems.com/images/products/Recombinant "SDS-PAGE: Recombinant Human p38 beta/MAPK11 His Protein [NBP1-72538]")
| Reactivity: | Human |
| Source: | E. coli |
| Applications: | AC |
| Reactivity: | Human |
| Applications: | AC |
Selective inhibitor of p38 MAPK
| Alternate Names: | Adezmapimod |
| Chemical Name: | 4-[5-(4-Fluorophenyl)-2-[4-(methylsulfonyl)phenyl]-1H-imidazol-4-yl]pyridine |
| Purity: | ≥98% |
Potent, selective inhibitor of p38 MAPK
| Chemical Name: | 4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol |
| Purity: | ≥99% |
High affinity and selective p38 kinase inhibitor
| Alternate Names: | Doramapimod |
| Chemical Name: | N-[3-(1,1-Dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N'-[4-[2-(4-morpholinyl)ethoxy]-1-naphthalenyl]urea |
| Purity: | ≥98% |
Selective inhibitor of p38 MAPK; water-soluble
| Chemical Name: | 4-[5-(4-Fluorophenyl)-2-[4-(methylsulphonyl)phenyl]-1H-imidazol-4-yl]pyridine hydrochloride |
| Purity: | ≥98% |
Selective p38 MAPK inhibitor
| Chemical Name: | 6-Chloro-5-[[(2R,5S)-4-[(4-fluorophenyl)methyl]-2,5-dimethyl-1-piperazinyl]carbonyl]-N,N,1-trimethyl-α-oxo-1H-Indole-3-acetamide hydrochloride |
| Purity: | ≥98% |
Selective inhibitor of p38α and p38β2
| Chemical Name: | (2-Methylphenyl)-[4-[(2-amino-4-bromophenyl)amino]-2-chlorophenyl]methanone |
| Purity: | ≥98% |
Potent, selective p38α and p38β inhibitor
| Chemical Name: | 4-[4-(4-Fluorophenyl)-1-(3-phenylpropyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]-3-butyn-1-ol |
| Purity: | ≥98% |
p38 MAPK inhibitor
| Chemical Name: | N-Cyano-N'-[2-[[8-(2,6-difluorophenyl)-4-(4-fluoro-2-methylphenyl)-7,8-dihydro-7-oxopyrido[2,3-d]pyrimidin-2-yl]amino]ethyl]guanidine |
| Purity: | ≥98% |
p38 MAPK inhibitor; anti-inflammatory
| Chemical Name: | N-Cyclopropyl-4-[4-(4-fluorophenyl)-2-(4-piperidinyl)-5-thiazolyl]-2-pyrimidinamine dihydrochloride |
| Purity: | ≥98% |
Potent and selective p38α/β inhibitor
| Chemical Name: | (-)-3-[3-Bromo-4-[(2,4-difluorophenyl)methoxy]-6-methyl-2-oxo-1(2H)-pyridinyl]-N,4-dimethylbenzamide |
| Purity: | ≥98% |
Potent and selective p38α and p38β Degrader (PROTAC®); active in vivo
| Chemical Name: | 3-(3-Bromo-4-((2,4-difluorobenzyl)oxy)-6-methyl-2-oxopyridin-1(2H)-yl)-N-(4-(1-(4-((4-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)butyl)amino)-4-oxobutyl)-1H-1,2,3-triazol-4-yl)butyl)-4-methylbenzamide |
| Purity: | ≥97% |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #280071 |
| Applications: | ICC/IF |
