9 results for "RNA Polymerase Inhibitors Small Molecules and Peptides" in Products
RNA Polymerase Inhibitors Small Molecules and Peptides
RNA Polymerases Classification
In eukaryotes, there are four forms of RNA polymerase (I-IV), which are classified on the basis of the type of RNA they produce. RNA polymerase I (Pol I) makes a pre-ribosomal RNA (pre-rRNA 45S), which makes up ~50% of the RNA produced in a cell; RNA polymerase II (Pol II), which makes precursors of mRNAs, most snRNA and microRNAs; RNA polymerase III (Pol III), which makes tRNAs and rRNA 5S, as well as other small RNAs found in the cell. RNA polymerase IV is an ...
Inhibits RNA polymerase
| Chemical Name: | 2-Amino-(N,N)-1-bis(hexadecahydro-6,13-diisopropyl-2,5,9-trimethyl-1,4,7,11,14-pentaoxo-1H-pyrrolo[2,1]-[1,4,7,10,13] oxatetraazacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide |
| Purity: | ≥95% |
Inhibitor of DNA and RNA polymerase
| Chemical Name: | (1S)-5-Deoxy-1-C-[(2S,3S)-7-[[2,6-dideoxy-3-O-(2,6-dideoxy-β-D-arabino-hexopyranosyl)-β-D-arabino-hexopyranosyl]oxy]-3-[(O-2,6-dideoxy-3-C-methyl-β-D-ribo-hexopyranosyl-(1.fwdarw.3)-O-2,6-dideoxy-β-D-lyxo-hexopyranosyl-(1.fwdarw.3)-2,6-dideoxy-β-D-arabino-hexopyranosyl)oxy]-1,2,3,4-tetrahydro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-1-O-methyl-D-threo-2-pentulose |
| Purity: | ≥95% |
Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral nucleotide prodrug
| Alternate Names: | GS-5734 |
| Chemical Name: | 2-Ethylbutyl (2S)-2-[[(S)-[[(2R,3S,4R,5R)-5-(4-aminopyrrolo(2,1-f)(1,2,4)triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl]methoxy]phenoxyphosphoryl]amino]propanoate |
| Purity: | ≥98% |
Inhibitor of RNA polymerase II
| Chemical Name: | cyclo[L-Asparaginyl-4-hydroxy-L-prolyl-(R)-4,5-dihydroxy-L-isoleucyl-6-hydroxy-2-mercapto-L-tryptophylglycyl-L-isoleucylglycyl-L-cysteinyl]cyclic (4→8)-sulfide (R)-S-oxide |
| Purity: | ≥95% |
RNA polymerase I inhibitor; also p53 pathway activator
| Chemical Name: | N-[2-(Dimethylamino)ethyl]-12-oxo-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide |
| Purity: | ≥98% |
Viral RNA polymerase inhibitor
| Alternate Names: | T 705 |
| Chemical Name: | 6-Fluoro-3,4-dihydro-3-oxo-2-pyrazinecarboxamide |
| Purity: | ≥98% |
Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral nucleotide
| Chemical Name: | (2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile |
| Purity: | ≥98% |
Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral
| Alternate Names: | BCX 4430 |
| Chemical Name: | (2S,3S,4R,5R)-2-(4-Amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-(hydroxymethyl)-3,4-pyrrolidinediol dihydrochloride |
| Purity: | ≥98% |
Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral nucleoside
| Chemical Name: | N-Hydroxycytidine |
| Purity: | ≥98% |
