19 results for "TR-FRET and FP Assay Reagents" in Products
TR-FRET and FP Assay Reagents
What is TR-FRET?
TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) is a highly sensitive and widely used assay technology in the field of drug discovery and biological research to study protein-protein interactions, enzyme kinetics, and receptor-ligand binding. This technology works by measuring the energy transfer between two fluorescent molecules - a donor (such as CoraFluor™) and an acceptor. When the donor molecule is excited by a light source, typically 340 nm, energy ...
Fluorescent ligand for α4β1 (VLA-4)
| Purity: | ≥90% |
Potent fluorescent PARP inhibitor; cell permeable
| Alternate Names: | AZD2281-BDY FL,Olaparib-BDY FL |
| Chemical Name: | (T-4)-[4-[[3-[[4-[3-[5-[(3,5-Dimethyl-2H-pyrrol-2-ylidene-κN)methyl]-1H-pyrrol-2-yl-κN-1-oxopropyl]-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2H)-phthalazinonato]difluoroboron |
| Purity: | ≥90% |
High affinity cereblon fluorescent probe
| Chemical Name: | 2-((1E,3E)-5-((E)-1-(6-((4-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)butyl)amino)-6-oxohexyl)-3,3-dimethyl-5-sulfoindolin-2-ylidene)penta-1,3-dien-1-yl)-1-ethyl-3,3-dimethyl-3H-indol-1-ium-5-sulfonate |
| Purity: | ≥90% |
Fluorescent cannabinoid ligand; fluorescent form of AM 251 (Cat. No. 1117)
| Chemical Name: | N-(Piperidin-1-yl)-5-(4-(4-(3-(5-carboxamidotetramethylrhodaminyl)propyl))phenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide |
| Purity: | ≥90% |
High-affinity VHL fluorescent probe for TR-FRET and FP assays
| Chemical Name: | (2S,4R)-1-((S)-2-(tert-Butyl)-21-(5,5-difluoro-7,9-dimethyl-5H-5λ4,6λ4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-3-yl)-4,19-dioxo-6,9,12,15-tetraoxa-3,18-diazahenicosanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide |
| Purity: | ≥95% |
High affinity fluorescent probe for TR-FRET cereblon binding assay
| Chemical Name: | 3-(5,5-Difluoro-7,9-dimethyl-5H-5λ4,6λ4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-3-yl)-N-(8-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)octyl)propenamide |
| Purity: | ≥95% |
Fluorescent BET bromodomain probe; suitable for use in TR-FRET
| Chemical Name: | (S)-5-(3-(1-(4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-2-oxo-7,10,13-trioxa-3-azahexadecan-16-yl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid trifluoroacetate |
| Purity: | ≥95% |
Terbium cryptate FRET donor for TR-FRET assay development; amine reactive for conjugation
Terbium cryptate FRET donor for TR-FRET assay development; amine reactive for conjugation
Selective hα1A adrenergic receptor fluorescent antagonist
| Purity: | ≥95% |
Fluorescent serotonin 5HT2B receptor ligand for HTS
| Purity: | ≥95% |
Potent and selective hA2B/A3 adenosine receptor fluorescent antagonist
| Purity: | ≥95% |
Potent and partially selective hD2 dopamine receptor fluorescent antagonist
| Purity: | ≥95% |
Fluorescent probe targeting kinases; kinase tracer for TR-FRET assays
| Purity: | ≥95% |
Fluorescein labeled XIAP ligand for TR-FRET assay development
| Purity: | ≥95% |
Terbium cryptate FRET donor for TR-FRET assay development, cysteine reactive for conjugation
SARS-CoV-2 main protease fluorescent ligand; TR-FRET acceptor
| Purity: | ≥95% |
Cell impermeable terbium cryptate FRET donor for TR-FRET assay development, with chloroalkane ligand
Cell permeable terbium cryptate FRET donor for TR-FRET assay development, with chloroalkane ligand
