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8 results for "TrkB Small Molecules and Peptides" in Products
TrkB Small Molecules and Peptides
Members of the Trk family (TrkA, B, and C) of receptor tyrosine kinases act as receptors for the neurotrophin family: BDNF, NGF, NT-3, and NT-4. Trks exhibit selectivity for specific neurotrophins. TrkA, TrkB and TrkC preferentially bind NGF, NT-4 and BDNF, and NT-3, respectively. All Trk family proteins share a common structural organization cons...
Potent TrkB agonist
| Chemical Name: | N,N',N''Tris(2-hydroxyethyl)-1,3,5-benzenetricarboxamide |
| Purity: | ≥98% |
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TrkB receptor antagonist
| Chemical Name: | N-[2-[[(Hexahydro-2-oxo-1H-azepin-3-yl)amino]carbonyl]phenyl]benzo[b]thiophene-2-carboxamide |
| Purity: | ≥98% |
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TrkB agonist
| Alternate Names: | 7,8-DHF |
| Chemical Name: | 7,8-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one |
| Purity: | ≥98% |
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Potent Trk inhibitor; inhibits TrkA, TrkB and TrkC
| Chemical Name: | N-[3-[[2,3-Dihydro-2-oxo-3-(1H-pyrrol-2-ylmethylene)-1H-indol-6-yl]amino]-4-methylphenyl]-N'-[2-fluoro-5-(trifluoromethyl)phenyl]urea |
| Purity: | ≥98% |
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TrkB receptor antagonist
| Purity: | ≥95% |
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TrkB and TrkC agonist; brain penetrant
| Chemical Name: | 2,2',2',2'''-[[(4-Chlorophenyl)methylene]bis(4,1-phenylenenitrilo)]tetrakisethanol |
| Purity: | ≥97% |
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Selective TrkB receptor agonist; neuroprotectant
| Chemical Name: | N-[2-(5-Hydroxy-1H-indol-3-yl)ethyl]-2-oxo-3-piperidinecarboxamide |
| Purity: | ≥98% |
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Potent and selective pan-Trk inhibitor; peripherally restricted
| Chemical Name: | N-[5-[[2-Amino-7-(2-hydroxy-1,1-dimethylethyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]carbonyl]-3-pyridinyl]-5-chloro-2-pyridineacetamide |
| Purity: | ≥98% |
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