CD117/c-kit Antibody (104D2) - BSA Free

Novus Biologicals | Catalog # NBP3-09161

Clone 104D2 was used by HLDA to establish CD designation.
Novus Biologicals
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Key Product Details

Species Reactivity

Human, Bovine, Primate

Applications

Immunohistochemistry, Immunohistochemistry-Frozen, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 104D2

Format

BSA Free
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Product Specifications

Immunogen

MOLM-1 megakaryocytic cells

Specificity

The mouse monoclonal antibody 104D2 detects extracellular part of CD117 / c-Kit protooncogen.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for CD117/c-kit Antibody (104D2) - BSA Free

Flow Cytometry: CD117/c-kit Antibody (104D2) - BSA Free [NBP3-09161]

Flow Cytometry: CD117/c-kit Antibody (104D2) - BSA Free [NBP3-09161]

Flow Cytometry: CD117/c-kit Antibody (104D2) [NBP3-09161] - (surface staining) of human peripheral blood cells with anti-CD117 (104D2) purified.

Applications for CD117/c-kit Antibody (104D2) - BSA Free

Application
Recommended Usage

Flow Cytometry

1 ug/ml

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Advanced Features

  • Spectra Viewer - Custom analysis of spectra from multiple fluorochromes
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  • Antigen Density Selector - Match fluorochrome brightness with antigen density
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Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

Phosphate buffered saline (PBS), pH 7.4

Format

BSA Free

Preservative

15mM Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CD117/c-kit

CD117 is a 145 kD immunoglobulin superfamily member, also known as c-Kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with it's ligand is critical for the development of hematopoietic stem cells. The 2B8 antibody does not block c-Kit activity.

Long Name

Stem Cell Factor Receptor

Alternate Names

c-kit, CD117, ckit, KIT, PBT, SCF R, SCFR

Gene Symbol

KIT

Additional CD117/c-kit Products

Product Documents for CD117/c-kit Antibody (104D2) - BSA Free

Certificate of Analysis

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Product Specific Notices for CD117/c-kit Antibody (104D2) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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