Human beta-Arrestin 1 Antibody

Catalog # Availability Size / Price Qty
Detection of Human  beta ‑Arrestin 1 by Western Blot.
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Human beta-Arrestin 1 Antibody Summary

Species Reactivity
Detects human beta -Arrestin 1 in direct ELISAs and Western blots.
Monoclonal Rat IgG2A Clone # 425817
Protein A or G purified from hybridoma culture supernatant
E. coli-derived recombinant human beta -Arrestin 1
Accession # P49407
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.


Recommended Concentration
Western Blot
2 µg/mL
See below
8-25 µg/mL
Immersion fixed paraffin-embedded sections of human colon cancer tissue

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Western Blot Detection of Human  beta ‑Arrestin 1 antibody by Western Blot. View Larger

Detection of Human beta ‑Arrestin 1 by Western Blot. Western blot shows lysates of human peripheral blood mononuclear cells under reducing (R) and non-reducing (NR) conditions. PVDF membrane was probed with 2 µg/mL Rat Anti-Human beta -Arrestin 1 Monoclonal Antibody (Catalog # MAB45601) followed by HRP-conjugated Anti-Rat IgG Secondary Antibody (Catalog # HAF005). A specific band for beta -Arrestin 1 was detected at approximately 60 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Preparation and Storage

Reconstitute at 0.5 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Size / Price
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: beta-Arrestin 1

The Arrestin family consists of four members: Arrestin 1 (visual Arrestin), Arrestin 2 ( beta -Arrestin 1), Arrestin 3 ( beta -Arrestin 2), and Arrestin 4 (cone Arrestin). While visual and cone Arrestins are found almost exclusively in the retina, beta -Arrestins 1 and 2 are ubiquitously expressed, and were initially described as negative regulators of G protein-coupled receptor (GPCR) signaling. More recently, beta -Arrestins have been determined to serve as scaffolds for various signaling pathways, including the MAPK cascades activating ERK2, p38 alpha, and JNK3. These beta -Arrestin scaffolds tie together the appropriate kinases in series, forming a discreet signaling module that localizes components to specific subcellular environments and facilitates greater kinase activation.

Entrez Gene IDs
408 (Human); 109689 (Mouse); 25387 (Rat)
Alternate Names
ARB1; ARR1; ARRB1; arrestin 2; Arrestin beta-1; arrestin, beta 1; betaArrestin 1; beta-Arrestin 1; beta-arrestin-1

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Isotype Controls

Reconstitution Buffers

Secondary Antibodies

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Human beta-Arrestin 1 Antibody
By Anonymous on 05/15/2022
Application: IHC Sample Tested: Spleen tissue Species: Human