Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Flow Cytometry

Cited:

Flow Cytometry

Label

Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)

Antibody Source

Monoclonal Mouse IgG1 Clone # L203
View all HLA-DR Primary Antibodies »

Product Specifications

Immunogen

RPMI 8866 human lymphoblastoid cells
Accession # P01903

Specificity

Detects human HLA‑DR.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Human HLA‑DR APC‑conjugated Antibody

Detection of HLA-DR antibody in Human Blood Lymphocytes antibody by Flow Cytometry.

Detection of HLA‑DR in Human Blood Lymphocytes by Flow Cytometry.

Human peripheral blood lymphocytes were stained with (A) Mouse Anti-Human HLA-DR APC-conjugated Monoclonal Antibody (Catalog # FAB4869A) or (B) isotype control antibody (Catalog # IC002A) Mouse anti-Human CD19 PE-conjugated Monoclonal Antibody (Catalog # FAB4867A). View our protocol for Staining Membrane-associated Proteins.

Applications for Human HLA‑DR APC‑conjugated Antibody

Application
Recommended Usage

Flow Cytometry

10 µL/106 cells
Sample: Human peripheral blood lymphocytes

Reviewed Applications

Read 1 review rated 4 using FAB4869A in the following applications:

Spectra Viewer

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Advanced Features

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  • Antigen Density Selector - Match fluorochrome brightness with antigen density
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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: HLA-DR

HLA-DR is a transmembrane human major histocompatibility complex 2 (MHC II) family member and consists of a 34 kDa (alpha) subunit and one of several 28 kDa (beta) subunits. HLA-DR is expressed primarily by B cells and dendritic cells (DC), in which it binds peptides derived from internalized and processed antigenic proteins. It presents these peptides on the cell surface for recognition by the T cell receptor on CD4+ T cells. This interaction is central to antigen specificity in the adaptive immune response. HLA-DR alleles, polymorphisms, and aberrant expression are linked to a variety of diseases including autoimmunity and cancer.

Long Name

Major Histocompatibility Complex Class II DR

Alternate Names

HLA-DRA, HLADR, MHC Class II DR

Entrez Gene IDs

3122 (Human)

Gene Symbol

HLA-DRA

UniProt

P01903

Additional HLA-DR Products

Product Documents for Human HLA‑DR APC‑conjugated Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human HLA‑DR APC‑conjugated Antibody

For research use only

Citations for Human HLA‑DR APC‑conjugated Antibody

Customer Reviews for Human HLA‑DR APC‑conjugated Antibody (1)

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  • Human HLA-DR APC-conjugated Antibody
    Name: Stephane Hua
    Application: Flow Cytometry
    Sample Tested: Dendritic cells
    Species: Human
    Verified Customer | Posted 07/05/2018

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