• Assay Type
    Solid Phase Sandwich ELISA
  • Format
    96-well strip plate
  • Assay Length
    4.5 hours
  • Sample Type & Volume Required Per Well
    Cell Culture Supernates (100 uL), Serum (100 uL), EDTA Plasma (100 uL), Heparin Plasma (100 uL), Citrate Plasma (100 uL)
  • Sensitivity
    0.7 pg/mL
  • Assay Range
    3.1 - 300 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma)
  • Specificity
    Natural and recombinant human IL-6
  • Cross-reactivity
    < 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
  • Interference
    No significant interference observed with available related molecules.
Control Available
QC01-1, Quantikine Immunoassay Control Group 1 - Please Inquire
Product Summary
The Quantikine Human IL-6 Immunoassay is a 4.5 hour solid phase ELISA designed to measure IL-6 in cell culture supernates, serum, and plasma. It contains recombinant human IL-6 and antibodies raised against recombinant human IL-6 and has been shown to accurately quantitate the recombinant factor. Results obtained using natural IL-6 showed linear curves that were parallel to the standard curves obtained using the E. coli-expressed Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural human IL-6.

Precision
Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision.
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision.
Cell Culture Supernates
Intra-Assay Precision Inter-Assay Precision
Sample123123
n202020202020
Mean15.895.617916.498.8188
Standard Deviation0.733.10.62.53.7
CV%4.43.11.73.72.52

Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma
Intra-Assay Precision Inter-Assay Precision
Sample123123
n202020202020
Mean16.897.718617.2101191
Standard Deviation0.71.63.81.13.37.2
CV%4.21.626.43.33.8

Recovery

The recovery of human IL-6 spiked to three different levels throughout the range of the assay in various matrices was evaluated.

Sample Type Average % Recovery Range %
Cell Culture Media (n=5) 98 94-103
Citrate Plasma (n=5) 91 82-95
EDTA Plasma (n=5) 95 84-101
Heparin Plasma (n=5) 90 88-98
Serum (n=5) 93 86-99
Linearity
To assess the linearity of the assay, four samples were spiked with high concentrations of IL-6 in various matrices and diluted with the appropriate Calibrator Diluent to produce samples with values within the dynamic range of the assay.
Human IL-6 Quantikine ELISA Kit
Preparation and Storage
  • Storage
    Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Background: IL-6
IL-6 (Interleukin-6) is a pleiotropic cytokine that acts in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression. It contributes to chronic inflammation in obesity, insulin resistance, inflammatory bowel disease, arthritis, sepsis, and atherosclerosis. IL-6 signals through a receptor complex of IL-6 R alpha and gp130. gp130 is also a component of the receptors for CLC, CNTF, CT-1, IL-11, IL-27, LIF, and OSM. Soluble forms of IL-6 R alpha are generated by both alternative splicing and proteolytic cleavage. In a mechanism known as trans-signaling, complexes of soluble IL-6 and IL-6 R alpha elicit responses from gp130-expressing cells that lack cell surface IL-6 R alpha.
    • Long Name
      Interleukin 6
    • Entrez Gene IDs
      3569 (Human); 16193 (Mouse); 24498 (Rat); 399500 (Porcine); 280826 (Bovine); 403985 (Canine); 100034196 (Equine); 493687 (Feline); 100008733 (Rabbit);
    • Alternate Names
      B cell stimulatory factor-2; B-cell differentiation factor; BSF-2; BSF2CTL differentiation factor; CDF; HGFHSFIFNB2Hybridoma growth factor; IFN-beta-2; IL6; IL-6; IL-6B-cell stimulatory factor 2; Interferon beta-2; interleukin 6 (interferon, beta 2); interleukin BSF-2; interleukin-6; MGI-2A;
    Related Research Areas
    Assay Procedure
    Refer to the product for complete assay procedure.

    Bring all reagents and samples to room temperature before use. It is recommended that all samples, standards, and controls be assayed in duplicate.
    1.   Prepare all reagents, standard dilutions, and samples as directed in the product insert.
    2.   Remove excess microplate strips from the plate frame, return them to the foil pouch containing the desiccant pack, and reseal.

    3. 100 µL Assay Diluent
    4.   Add 100 µL of Assay Diluent to each well.

    5. 100 µL Standard, Control, or Sample
    6.   Add 100 µL of Standard, control, or sample to each well. Cover with a plate sealer, and incubate at room temperature for 2 hours.
    7.   Aspirate each well and wash, repeating the process 3 times for a total of 4 washes.

    8. 200 µL Conjugate
    9.   Add 200 µL of Conjugate to each well. Cover with a new plate sealer, and incubate at room temperature for 2 hours.
    10.   Aspirate and wash 4 times.

    11. 200 µL Substrate Solution
    12.   Add 200 µL Substrate Solution to each well. Incubate at room temperature for 20 minutes. PROTECT FROM LIGHT.

    13. 50 µL Stop Solution
    14.   Add 50 µL of Stop Solution to each well. Read at 450 nm within 30 minutes. Set wavelength correction to 540 nm or 570 nm.
    Citations:

    R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

    286 Citations: Showing 1 - 10
    Filter your results:

    Species
    Sample Type
    1. Improvement in asymmetric dimethylarginine and oxidative stress in patients with limb salvage after autologous mononuclear stem cell application for critical limb ischemia
      Authors: J Madaric, M Valachovic, L Paulis, J Pribojova, R Mateova, K Sebekova, L Postulkova, T Madaricova, M Bucova, M Mistrik, I Vulev
      Stem Cell Res Ther, 2017;8(1):165.
      Species: Human
      Sample Type: Cell Culture Supernates
    2. A bio-behavioral intervention to decrease intravaginal practices and bacterial vaginosis among HIV infected Zambian women, a randomized pilot study
      Authors: ML Alcaide, M Chisembele, E Malupande, VJ Rodriguez, MA Fischl, K Arheart, DL Jones
      BMC Infect. Dis., 2017;17(1):338.
      Species: Human
      Sample Type: Vaginal Lavage
    3. Tumor necrosis factor alpha inhibitors have no effect on a human T-lymphotropic virus type-I (HTLV-I)-infected cell line from patients with HTLV-I-associated myelopathy
      Authors: S Fukui, H Nakamura, Y Takahashi, N Iwamoto, H Hasegawa, K Yanagihara, T Nakamura, A Okayama, A Kawakami
      BMC Immunol, 2017;18(1):7.
      Species: Human
      Sample Type: Cell Culture Supernates
    4. High serum resistin associates with intrahepatic inflammation and necrosis: an index of disease severity for patients with chronic HBV infection
      Authors: Z Meng, Y Zhang, Z Wei, P Liu, J Kang, Y Zhang, D Ma, C Ke, Y Chen, J Luo, Z Gong
      BMC Gastroenterol, 2017;17(1):6.
      Species: Human
      Sample Type: Serum
    5. Serum YB-1 (Y-box binding protein 1) as a biomarker of bone disease progression in patients with breast cancer and bone metastases
      Authors: AR Ferreira, M Bettencour, I Alho, AL Costa, AR Sousa, A Mansinho, C Abreu, C Pulido, D Macedo, I Vendrell, TR Pacheco, L Costa, S Casimiro
      J Bone Oncol, 2017;6(0):16-21.
      Species: Human
      Sample Type: Serum
    6. Cigarette Smoke Impairs A2A Adenosine Receptor Mediated Wound Repair through Up-regulation of Duox-1 Expression
      Authors: Z Tian, H Zhang, J Dixon, N Traphagen, TA Wyatt, K Kharbanda, S Simet Chad, N Kolliputi, DS Allen-Gips
      Sci Rep, 2017;7(0):44405.
      Species: Human
      Sample Type: Cell Culture Supernates
    7. The long non-coding RNA TP73-AS1 modulates HCC cell proliferation through miR-200a-dependent HMGB1/RAGE regulation
      Authors: S Li, Y Huang, Y Huang, Y Fu, D Tang, R Kang, R Zhou, XG Fan
      J. Exp. Clin. Cancer Res., 2017;36(1):51.
      Species: Human
      Sample Type: Cell Culture Supernates
    8. Interleukin-6 increases the expression and activity of insulin-degrading enzyme
      Authors: MA Kurauti, JM Costa-Júni, SM Ferreira, GJ Santos, CHG Sponton, EM Carneiro, GD Telles, MPT Chacon-Mik, CR Cavaglieri, LF Rezende, AC Boschero
      Sci Rep, 2017;7(0):46750.
      Species: Human
      Sample Type: Plasma
    9. Toll-like receptor polymorphisms compromise the inflammatory response against bacterial antigen translocation in cirrhosis
      Authors: P Piñero, O Juanola, E Caparrós, P Zapater, P Giménez, JM González-N, J Such, R Francés
      Sci Rep, 2017;7(0):46425.
      Species: Human
      Sample Type: Serum
    10. Myeloid-derived suppressor cells are increased and correlated with type 2 immune responses, malnutrition, inflammation, and poor prognosis in patients with breast cancer
      Authors: K Gonda, M Shibata, T Ohtake, Y Matsumoto, K Tachibana, N Abe, H Ohto, K Sakurai, S Takenoshit
      Oncol Lett, 2017;14(2):1766-1774.
      Species: Human
      Sample Type: Cell Culture Supernates
    11. Serum high mobility group box-1 and osteoprotegerin levels are associated with peripheral arterial disease and critical limb ischemia in type 2 diabetic subjects
      Authors: S Giovannini, G Tinelli, F Biscetti, G Straface, F Angelini, D Pitocco, L Mucci, R Landolfi, A Flex
      Cardiovasc Diabetol, 2017;16(1):99.
      Species: Human
      Sample Type: Serum
    12. Elevated CRP levels predict poor outcome and tumor recurrence in patients with thymic epithelial tumors: A pro- and retrospective analysis
      Authors: S Janik, C Bekos, P Hacker, T Raunegger, B Ghanim, E Einwallner, L Beer, W Klepetko, L Müllauer, HJ Ankersmit, B Moser
      Oncotarget, 2017;8(29):47090-47102.
      Species: Human
      Sample Type: Serum
    13. Expression of hemoglobin-? and ? subunits in human vaginal epithelial cells and their functional significance
      Authors: D Saha, S Koli, M Patgaonkar, KV Reddy
      PLoS ONE, 2017;12(2):e0171084.
      Species: Human
      Sample Type: Cell Culture Supernates
    14. Overexpression of GLP-1 receptors suppresses proliferation and cytokine release by airway smooth muscle cells of patients with chronic obstructive pulmonary disease via activation of ABCA1
      Authors: YH Sun, L He, MY Yan, RQ Zhao, B Li, F Wang, Y Yang, HP Yu
      Mol Med Rep, 2017;0(0):.
    15. Elastin?derived peptides are involved in the processes of human temporomandibular disorder by inducing inflammatory responses in synovial cells
      Authors: K Kobayashi, R Jokaji, M Miyazawa-H, S Takatsuka, A Tanaka, K Ooi, H Nakamura, S Kawashiri
      Mol Med Rep, 2017;16(3):3147-3154.
      Species: Human
      Sample Type: Synovial Fluid
    16. Serum fatty acid-binding protein 4 (FABP4) concentration is associated with insulin resistance in peripheral tissues, A clinical study
      Authors: R Nakamura, T Okura, Y Fujioka, K Sumi, K Matsuzawa, S Izawa, E Ueta, M Kato, SI Taniguchi, K Yamamoto
      PLoS ONE, 2017;12(6):e0179737.
      Species: Human
      Sample Type: Plasma
    17. Concurrent Aerobic and Resistance Training Has Anti-Inflammatory Effects and Increases Both Plasma and Leukocyte Levels of IGF-1 in Late Middle-Aged Type 2 Diabetic Patients
      Authors: G Annibalini, F Lucertini, D Agostini, L Vallorani, A Gioacchini, E Barbieri, M Guescini, L Casadei, A Passalia, M Del Sal, G Piccoli, M Andreani, A Federici, V Stocchi
      Oxid Med Cell Longev, 2017;2017(0):3937842.
      Species: Human
      Sample Type: Plasma
    18. Correlation between plasma endothelin-1 levels and severity of septic liver failure quantified by maximal liver function capacity (LiMAx test). A prospective study
      Authors: MF Kaffarnik, N Ahmadi, JF Lock, T Wuensch, J Pratschke, M Stockmann, M Malinowski
      PLoS ONE, 2017;12(5):e0178237.
      Species: Human
      Sample Type: Plasma
    19. Synergistic IL-6 and IL-8 paracrine signalling pathway infers a strategy to inhibit tumour cell migration
      Authors: H Jayatilaka, P Tyle, JJ Chen, M Kwak, J Ju, HJ Kim, JSH Lee, PH Wu, DM Gilkes, R Fan, D Wirtz
      Nat Commun, 2017;8(0):15584.
      Species: Human
      Sample Type: Cell Culture Supernates
    20. Profiling of cytokines, chemokines and other soluble proteins as a potential biomarker in colorectal cancer and polyps
      Authors: NA Johdi, L Mazlan, I Sagap, R Jamal
      Cytokine, 2017;99(0):35-42.
      Species: Human
      Sample Type: Serum
    21. Fibroblast growth factor 23, iron and inflammation - are they related in early stages of chronic kidney disease?
      Authors: E Lukaszyk, M Lukaszyk, E Koc-Zoraws, A Bodzenta-L, J Malyszko
      Arch Med Sci, 2017;13(4):845-850.
      Species: Human
      Sample Type: Serum
    22. The RB-IL-6 axis controls self-renewal and endocrine therapy resistance by fine-tuning mitochondrial activity
      Authors: S Kitajima, A Yoshida, S Kohno, F Li, S Suzuki, N Nagatani, Y Nishimoto, N Sasaki, H Muranaka, Y Wan, TC Thai, N Okahashi, F Matsuda, H Shimizu, T Nishiuchi, Y Suzuki, K Tominaga, N Gotoh, M Suzuki, ME Ewen, DA Barbie, O Hirose, T Tanaka, C Takahashi
      Oncogene, 2017;0(0):.
      Species: Human
      Sample Type: Cell Culture Supernates
    23. Immunological and Inflammatory Impact of Non-Intubated Lung Metastasectomy
      Authors: TC Mineo, F Sellitri, G Vanni, FT Gallina, V Ambrogi
      Int J Mol Sci, 2017;18(7):.
      Species: Human
      Sample Type: Cell Culture Supernates
    24. Maslinic acid suppresses the growth of human gastric cells by inducing apoptosis via inhibition of the interleukin-6 mediated Janus kinase/signal transducer and activator of transcription 3 signaling pathway
      Authors: D Wang, S Tang, Q Zhang
      Oncol Lett, 2017;13(6):4875-4881.
      Species: Human
      Sample Type: Cell Culture Supernates
    25. ACN9 Regulates the Inflammatory Responses in Human Bronchial Epithelial Cells
      Authors: JH Jeong, J Kim, J Kim, HR Heo, JS Jeong, YJ Ryu, Y Hong, SS Han, SH Hong, SJ Lee, WJ Kim
      Tuberc Respir Dis (Seoul), 2017;80(3):247-254.
      Species: Human
      Sample Type: Cell Culture Supernates
    26. Impact of periodontal intervention on local inflammation, periodontitis, and HIV outcomes
      Authors: J Valentine, T Saladyanan, K Ramsey, J Blake, T Morelli, J Southerlan, EB Quinlivan, C Phillips, J Nelson, K DeParis, J Webster-Cy
      Oral Dis, 2016;0(0):87-97.
      Species: Human
      Sample Type: Saliva
    27. Neopterin and interleukin-6 as predictors of recurrent atrial fibrillation
      Anatol J Cardiol, 2016;16(8):563-571.
      Species: Human
      Sample Type: Plasma
    28. Modulation of Endothelial Inflammation by Low and High Magnitude Cyclic Stretch
      PLoS ONE, 2016;11(4):e0153387.
      Species: Human
      Sample Type: Cell Culture Supernates
    29. High throughput chemical library screening identifies a novel p110-? inhibitor that potentiates the anti-myeloma effect of bortezomib
      Oncotarget, 2016;7(25):38523-38538.
      Species: Human
      Sample Type: Cell Culture Supernates
    30. Neutrophil-derived microparticles are released into the coronary circulation following percutaneous coronary intervention in acute coronary syndromes
      Biosci. Rep, 2016;0(0):.
      Species: Human
      Sample Type: Plasma
    31. IL-6 trans-signaling is another pathway to upregulate Osteopontin
      Cytokine, 2016;90(0):88-95.
      Species: Human
      Sample Type: Cell Culture Supernates
    32. Sulforaphane improves chemotherapy efficacy by targeting cancer stem cell-like properties via the miR-124/IL-6R/STAT3 axis
      Sci Rep, 2016;6(0):36796.
      Species: Human
      Sample Type: Cell Culture Supernates
    33. Bacteroides are associated with GALT iNKT cell function and reduction of microbial translocation in HIV-1 infection
      Authors: D Paquin-Pro, C Ching, I Vujkovic-C, D Fadrosh, L Loh, Y Huang, M Somsouk, SV Lynch, PW Hunt, DF Nixon, D SenGupta
      Mucosal Immunol, 2016;0(0):.
      Species: Human
      Sample Type: Plasma
    34. Serum Interleukin-18, Fetuin-A, Soluble Intercellular Adhesion Molecule-1, and Endothelin-1 in Ankylosing Spondylitis, Psoriatic Arthritis, and SAPHO Syndrome
      Int J Mol Sci, 2016;17(8):.
      Species: Human
      Sample Type: Serum
    35. Nuclear DNA damage-triggered NLRP3 inflammasome activation promotes UVB-induced inflammatory responses in human keratinocytes
      Authors: Tatsuya Hasegawa
      Biochem Biophys Res Commun, 2016;0(0):.
      Species: Human
      Sample Type: Cell Culture Supernates
    36. Snake venom causes apoptosis by increasing the reactive oxygen species in colorectal and breast cancer cell lines
      Onco Targets Ther, 2016;9(0):6485-6498.
      Species: Human
      Sample Type: Cell Culture Supernates
    37. Analysis of VEGFA Variants and Changes in VEGF Levels Underscores the Contribution of VEGF to Polycystic Ovary Syndrome
      PLoS ONE, 2016;11(11):e0165636.
      Species: Human
      Sample Type: Plasma
    38. P2X7 Receptor Inhibition Improves CD34 T-Cell Differentiation in HIV-Infected Immunological Nonresponders on c-ART
      Authors: I Menkova-Ga, H Hocini, E Foucat, P Tisserand, L Bourdery, C Delaugerre, C Benne, Y Lévy, JD Lelièvre
      PLoS Pathog, 2016;12(4):e1005571.
      Species: Human
      Sample Type: Plasma
    39. Dysregulated JAK2 expression by TrkC promotes metastasis potential, and EMT program of metastatic breast cancer
      Sci Rep, 2016;6(0):33899.
      Species: Human
      Sample Type: Cell Culture Supernates
    40. Microenvironment-dependent growth of preneoplastic and malignant plasma cells in humanized mice
      Authors: R Das, T Strowig, R Verma, S Koduru, A Hafemann, S Hopf, MH Kocoglu, C Borsotti, L Zhang, A Branagan, E Eynon, MG Manz, RA Flavell, MV Dhodapkar
      Nat. Med., 2016;22(11):1351-1357.
      Species: Human
      Sample Type: Serum
    41. Transcript-activated collagen matrix as sustained mRNA delivery system for bone regeneration
      J Control Release, 2016;239(0):137-148.
      Species: Human
      Sample Type: Cell Culture Supernates
    42. Mitogen-activated protein kinases are required for effective infection of human choroid plexus epithelial cells by Listeria monocytogenes
      Microbes Infect, 2016;0(0):.
      Species: Human
      Sample Type: Cell Culture Supernates
    43. Regulation of Circulating Hematopoietic Stem/Progenitor Cells in Preterm Infants with Septicemia
      Stem Cells Dev, 2016;0(0):.
      Species: Human
      Sample Type: Plasma
    44. Data on clinical significance of second trimester inflammatory biomarkers in the amniotic fluid in predicting preterm delivery
      Data Brief, 2016;9(0):47-50.
      Species: Human
      Sample Type: Amniotic Fluid
    45. Associations between measures of vascular structure and function and systemic circulating blood markers in humans
      Physiol Rep, 2016;4(18):.
      Species: Human
      Sample Type: Serum
    46. MicroRNA-155 influences B-cell function through PU.1 in rheumatoid arthritis
      Nat Commun, 2016;7(0):12970.
      Species: Human
      Sample Type: Plasma
    47. Unexpected Normal Colloid Osmotic Pressure in Clinical States with Low Serum Albumin
      PLoS ONE, 2016;11(7):e0159839.
      Species: Human
      Sample Type: Serum
    48. Stability of cytokines, chemokines and soluble activation markers in unprocessed blood stored under different conditions
      Cytokine, 2016;84(0):17-24.
      Species: Human
      Sample Type: Plasma
    49. Human lung fibroblasts may modulate dendritic cell phenotype and function: results from a pilot in vitro study
      Authors: O Freynet, J Marchal-So, F Jean-Louis, A Mailleux, B Crestani, P Soler, L Michel
      Respir Res, 2016;17(1):36.
      Species: Human
      Sample Type: Cell Culture Supernates
    50. The oncometabolite R-2-hydroxyglutarate activates NF-?B-dependent tumor-promoting stromal niche for acute myeloid leukemia cells
      Sci Rep, 2016;6(0):32428.
      Species: Human
      Sample Type: Cell Culture Supernates
    51. Simple Plex() : A Novel Multi-Analyte, Automated Microfluidic Immunoassay Platform for the Detection of Human and Mouse Cytokines and Chemokines.
      Authors: Aldo P, Marusov G, Svancara D, David J, Mor G
      Am J Reprod Immunol, 2016;75(6):678-93.
      Species: Human
      Sample Type: Plasma
    52. Innovative Flow Cytometry Allows Accurate Identification of Rare Circulating Cells Involved in Endothelial Dysfunction
      PLoS ONE, 2016;11(8):e0160153.
      Species: Human
      Sample Type: Plasma
    53. A point mutation in AgrC determines cytotoxic or colonizing properties associated with phenotypic variants of ST22 MRSA strains
      Authors: S Mairpady S, N Siemens, IR Monk, DB Mohan, S Mukundan, KC Krishnan, S Prabhakara, J Snäll, A Kearns, F Vandenesch, M Svensson, M Kotb, B Gopal, G Arakere, A Norrby-Teg
      Sci Rep, 2016;6(0):31360.
      Species: Human
      Sample Type: Tissue Culture Supernates
    54. Pancreatic stellate cell secreted IL-6 stimulates STAT3 dependent invasiveness of pancreatic intraepithelial neoplasia and cancer cells
      Authors: NS Nagathihal, JA Castellano, MN VanSaun, X Dai, M Ambrose, Q Guo, Y Xiong, NB Merchant
      Oncotarget, 2016;7(40):65982-65992.
      Species: Human
      Sample Type: Serum
    55. A Novel IL6 Antibody Sensitizes Multiple Tumor Types to Chemotherapy Including Trastuzumab-Resistant Tumors.
      Authors: Zhong H, Davis A, Ouzounova M, Carrasco R, Chen C, Breen S, Chang Y, Huang J, Liu Z, Yao Y, Hurt E, Moisan J, Fung M, Tice D, Clouthier S, Xiao Z, Wicha M, Korkaya H, Hollingsworth R
      Cancer Res, 2016;76(2):480-90.
      Species: Human
      Sample Type: Cell Culture Supernates
    56. Association between mannose-binding lectin variants, haplotypes and risk of hepatocellular carcinoma: A case-control study
      Sci Rep, 2016;6(0):32147.
      Species: Human
      Sample Type: Plasma
    57. Pre-treatment neutrophil to lymphocyte ratio predicts the chemoradiotherapy outcome and survival in patients with oral squamous cell carcinoma: a retrospective study.
      Authors: Nakashima H, Matsuoka Y, Yoshida R, Nagata M, Hirosue A, Kawahara K, Sakata J, Arita H, Hiraki A, Nakayama H
      BMC Cancer, 2016;16(1):41.
      Species: Human
      Sample Type: Serum
    58. Inflammation-regulating factors in ascites as predictive biomarkers of drug resistance and progression-free survival in serous epithelial ovarian cancers.
      Authors: Lane D, Matte I, Garde-Granger P, Laplante C, Carignan A, Rancourt C, Piche A
      BMC Cancer, 2015;15(0):492.
    59. A randomized, placebo controlled trial of omega-3 fatty acids in the treatment of young children with autism.
      Authors: Mankad D, Dupuis A, Smile S, Roberts W, Brian J, Lui T, Genore L, Zaghloul D, Iaboni A, Marcon P, Anagnostou E
      Mol Autism, 2015;6(0):18.
      Species: Human
      Sample Type: Plasma
    60. The effect of the decoy molecule PA401 on CXCL8 levels in bronchoalveolar lavage fluid of patients with cystic fibrosis.
      Authors: McElvaney O, O'Reilly N, White M, Lacey N, Pohl K, Gerlza T, Bergin D, Kerr H, McCarthy C, O'Brien M, Adage T, Kungl A, Reeves E, McElvaney N
      Mol Immunol, 2015;63(2):550-8.
      Species: Human
      Sample Type: BALF
    61. Serum levels of inflammatory markers in depressed elderly patients with diabetes and mild cognitive impairment.
      Authors: Gorska-Ciebiada M, Saryusz-Wolska M, Borkowska A, Ciebiada M, Loba J
      PLoS ONE, 2015;10(3):e0120433.
      Species: Human
      Sample Type: Serum
    62. An association between abnormal bone turnover, systemic inflammation, and osteoporosis in patients with chronic pancreatitis: a case-matched study.
      Authors: Duggan S, Purcell C, Kilbane M, O'Keane M, McKenna M, Gaffney P, Ridgway P, Boran G, Conlon K
      Am J Gastroenterol, 2015;110(2):336-45.
      Species: Human
      Sample Type: Serum
    63. The Association between Serum Cytokines and Damage to Large and Small Nerve Fibers in Diabetic Peripheral Neuropathy.
      Authors: Magrinelli F, Briani C, Romano M, Ruggero S, Toffanin E, Triolo G, Peter G, Praitano M, Lauriola M, Zanette G, Tamburin S
      J Diabetes Res, 2015;2015(0):547834.
      Species: Human
      Sample Type: Serum
    64. The ATP Receptors P2X7 and P2X4 Modulate High Glucose and Palmitate-Induced Inflammatory Responses in Endothelial Cells.
      Authors: Sathanoori R, Sward K, Olde B, Erlinge D
      PLoS ONE, 2015;10(5):e0125111.
      Species: Human
      Sample Type: Cell Culture Supernates
    65. The N terminus of type III secretion needle protein YscF from Yersinia pestis functions to modulate innate immune responses.
      Authors: Osei-Owusu P, Jessen Condry D, Toosky M, Roughead W, Bradley D, Nilles M
      Infect Immun, 2015;83(4):1507-22.
      Species: Human
      Sample Type: Cell Culture Supernates
    66. MyD88-Dependent Signaling Decreases the Antitumor Efficacy of Epidermal Growth Factor Receptor Inhibition in Head and Neck Cancer Cells.
      Authors: Koch A, Love-Homan L, Espinosa-Cotton M, Stanam A, Simons A
      Cancer Res, 2015;75(8):1657-67.
      Species: Human
      Sample Type: Cell Culture Supernates
    67. Dietary Omega-3 Fatty Acid Supplementation Reduces Inflammation in Obese Pregnant Women: A Randomized Double-Blind Controlled Clinical Trial.
      Authors: Haghiac M, Yang X, Presley L, Smith S, Dettelback S, Minium J, Belury M, Catalano P, Hauguel-De Mouzon S
      PLoS ONE, 2015;10(9):e0137309.
      Species: Human
      Sample Type: Plasma
    68. EphB4 Expressing Stromal Cells Exhibit an Enhanced Capacity for Hematopoietic Stem Cell Maintenance.
      Authors: Nguyen T, Arthur A, Panagopoulos R, Paton S, Hayball J, Zannettino A, Purton L, Matsuo K, Gronthos S
      Stem Cells, 2015;33(9):2838-49.
      Species: Human
      Sample Type: Cell Culture Supernates
    69. Phosphocholine-Modified Macromolecules and Canonical Nicotinic Agonists Inhibit ATP-Induced IL-1beta Release.
      Authors: Hecker A, Kullmar M, Wilker S, Richter K, Zakrzewicz A, Atanasova S, Mathes V, Timm T, Lerner S, Klein J, Kaufmann A, Bauer S, Padberg W, Kummer W, Janciauskiene S, Fronius M, Schweda E, Lochnit G, Grau V
      J Immunol, 2015;195(5):2325-34.
      Species: Human
      Sample Type: Cell Culture Supernates
    70. Deleted in malignant brain tumors 1 (DMBT1) elicits increased VEGF and decreased IL-6 production in type II lung epithelial cells.
      Authors: Muller H, Nagel C, Weiss C, Mollenhauer J, Poeschl J
      BMC Pulm Med, 2015;15(0):32.
      Species: Human
      Sample Type: Cell Culture Supernates
    71. Association between Sleep Duration, Insomnia Symptoms and Bone Mineral Density in Older Boston Puerto Rican Adults.
      Authors: Niu J, Sahni S, Liao S, Tucker K, Dawson-Hughes B, Gao X
      PLoS ONE, 2015;10(7):e0132342.
      Species: Human
      Sample Type: Serum
    72. A Dietary Supplement Containing Cinnamon, Chromium and Carnosine Decreases Fasting Plasma Glucose and Increases Lean Mass in Overweight or Obese Pre-Diabetic Subjects: A Randomized, Placebo-Controlled Trial.
      Authors: Liu Y, Cotillard A, Vatier C, Bastard J, Fellahi S, Stevant M, Allatif O, Langlois C, Bieuvelet S, Brochot A, Guilbot A, Clement K, Rizkalla S
      PLoS ONE, 2015;10(9):e0138646.
      Species: Human
      Sample Type: Plasma
    73. Secreted ectodomain of sialic acid-binding Ig-like lectin-9 and monocyte chemoattractant protein-1 promote recovery after rat spinal cord injury by altering macrophage polarity.
      Authors: Matsubara K, Matsushita Y, Sakai K, Kano F, Kondo M, Noda M, Hashimoto N, Imagama S, Ishiguro N, Suzumura A, Ueda M, Furukawa K, Yamamoto A
      J Neurosci, 2015;35(6):2452-64.
      Species: Rat
      Sample Type: Cell Culture Supernates
    74. Increased FGF23 serum level is associated with unstable carotid plaque in type 2 diabetic subjects with internal carotid stenosis.
      Authors: Biscetti F, Straface G, Porreca C, Bertoletti G, Vincenzoni C, Snider F, Stigliano E, Arena V, Angelini F, Pecorini G, Bianchi A, Landolfi R, Flex A
      Cardiovasc Diabetol, 2015;14(0):139.
      Species: Human
      Sample Type: Serum
    75. WNT5A induces release of exosomes containing pro-angiogenic and immunosuppressive factors from malignant melanoma cells.
      Authors: Ekstrom E, Bergenfelz C, von Bulow V, Serifler F, Carlemalm E, Jonsson G, Andersson T, Leandersson K
      Mol Cancer, 2014;13(0):88.
      Species: Human
      Sample Type: Cell Culture Supernates
    76. Autophagy facilitates TLR4- and TLR3-triggered migration and invasion of lung cancer cells through the promotion of TRAF6 ubiquitination.
      Authors: Zhan Z, Xie X, Cao H, Zhou X, Zhang X, Fan H, Liu Z
      Autophagy, 2014;10(2):257-68.
      Species: Human
      Sample Type: Cell Culture Supernates
    77. Phosphoproteomic profiling reveals IL6-mediated paracrine signaling within the Ewing sarcoma family of tumors.
      Authors: Anderson J, Titz B, Akiyama R, Komisopoulou E, Park A, Tap W, Graeber T, Denny C
      Mol Cancer Res, 2014;12(12):1740-54.
      Species: Human
      Sample Type: Cell Culture Supernates
    78. Analysis of plasma cytokines and angiogenic factors in patients with pretreated urothelial cancer receiving Pazopanib: the role of circulating interleukin-8 to enhance the prognostic accuracy.
      Authors: Necchi A, Pennati M, Zaffaroni N, Landoni E, Giannatempo P, Raggi D, Schwartz L, Morosi C, Crippa F, Fare E, Nicolai N, Lanocita R, Sava T, Sacco C, Messina C, Ortega C, De Braud F, Salvioni R, Daidone M, Gianni A, Mariani L
      Br J Cancer, 2014;110(1):26-33.
      Species: Human
      Sample Type: Plasma
    79. Mucosal biomarkers of colorectal cancer risk do not increase at 6 months following sleeve gastrectomy, unlike gastric bypass.
      Authors: Kant P, Perry S, Dexter S, Race A, Loadman P, Hull M
      Obesity (Silver Spring), 2014;22(1):202-10.
      Species: Human
      Sample Type: Serum
    80. OPG/RANKL/RANK axis is a critical inflammatory signaling system in ischemic brain in mice.
      Authors: Shimamura M, Nakagami H, Osako M, Kurinami H, Koriyama H, Zhengda P, Tomioka H, Tenma A, Wakayama K, Morishita R
      Proc Natl Acad Sci U S A, 2014;111(22):8191-6.
      Species: Mouse
      Sample Type: Cell Culture Supernates
    81. Metabolic implications when employing heavy pre- and post-exercise rapid-acting insulin reductions to prevent hypoglycaemia in type 1 diabetes patients: a randomised clinical trial.
      Authors: Campbell M, Walker M, Trenell M, Luzio S, Dunseath G, Tuner D, Bracken R, Bain S, Russell M, Stevenson E, West D
      PLoS ONE, 2014;9(5):e97143.
      Species: Human
      Sample Type: Serum
    82. Vitamin D insufficiency and subclinical atherosclerosis in non-diabetic males living with HIV.
      Authors: Portilla J, Moreno-Perez O, Serna-Candel C, Escoin C, Alfayate R, Reus S, Merino E, Boix V, Giner L, Sanchez-Paya J, Pico A
      J Int AIDS Soc, 2014;17(0):18945.
      Species: Human
      Sample Type: Serum
    83. Prostate stromal cells express the progesterone receptor to control cancer cell mobility.
      Authors: Yu, Yue, Lee, Jennifer, Xie, Ning, Li, Estelle, Hurtado-Coll, Antonio, Fazli, Ladan, Cox, Michael, Plymate, Stephen, Gleave, Martin, Dong, Xuesen
      PLoS ONE, 2014;9(3):e92714.
      Species: Human
      Sample Type: Cell Culture Supernates
    84. Osteosarcoma cells promote the production of pro-tumor cytokines in mesenchymal stem cells by inhibiting their osteogenic differentiation through the TGF-beta/Smad2/3 pathway.
      Authors: Tu B, Peng Z, Fan Q, DU L, Yan W, Tang T
      Exp Cell Res, 2014;320(1):164-73.
      Species: Human
      Sample Type: Cell Culture Supernates
    85. Interleukin-6, age, and corpus callosum integrity.
      Authors: Bettcher, Brianne, Watson, Christa, Walsh, Christin, Lobach, Iryna V, Neuhaus, John, Miller, Joshua W, Green, Ralph, Patel, Nihar, Dutt, Shubir, Busovaca, Edgar, Rosen, Howard J, Yaffe, Kristine, Miller, Bruce L, Kramer, Joel H
      PLoS ONE, 2014;9(9):e106521.
      Species: Human
      Sample Type: Plasma
    86. Interleukin 4, interleukin 6 and osteopontin-serological markers of head and neck malignancy in primary diagnostics: A pilot study.
      Authors: Aderhold C, Grobschmidt G, Sauter A, Faber A, Hormann K, Schultz J
      Oncol Lett, 2014;8(3):1112-1118.
      Species: Human
      Sample Type: Serum
    87. Endothelial cell-derived interleukin-6 regulates tumor growth.
      Authors: Neiva K, Warner K, Campos M, Zhang Z, Moren J, Danciu T, Nor J
      BMC Cancer, 2014;14(0):99.
      Species: Human
      Sample Type: Cell Culture Supernates
    88. Elevated serum interleukin-18 level is associated with all-cause mortality in stable hemodialysis patients independently of cardiac dysfunction.
      Authors: Liu Y, Su C, Chang Y, Tsai W, Su Y, Wang S, Yang C, Tsai L, Chen J, Sung J
      PLoS ONE, 2014;9(3):e89457.
      Species: Human
      Sample Type: Serum
    89. Effect of a specific supplement enriched with n-3 polyunsaturated fatty acids on markers of inflammation, oxidative stress and metabolic status of ear, nose and throat cancer patients.
      Authors: Roca-Rodriguez M, Garcia-Almeida J, Lupianez-Perez Y, Rico J, Toledo M, Alcaide-Torres J, Cardona F, Medina J, Tinahones F
      Oncol Rep, 2014;31(1):405-14.
      Species: Human
      Sample Type: Serum
    90. Chemically modified DNA aptamers bind interleukin-6 with high affinity and inhibit signaling by blocking its interaction with interleukin-6 receptor.
      Authors: Gupta, Shashi, Hirota, Masao, Waugh, Sheela M, Murakami, Ikuo, Suzuki, Tomoki, Muraguchi, Masahiro, Shibamori, Masafumi, Ishikawa, Yuichi, Jarvis, Thale C, Carter, Jeffrey, Zhang, Chi, Gawande, Bharat, Vrkljan, Michael, Janjic, Nebojsa, Schneider, Daniel J
      J Biol Chem, 2014;289(12):8706-19.
      Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
      Sample Type: Cell Culture Supernates
    91. Oxidative and pro-inflammatory impact of regular and denicotinized cigarettes on blood brain barrier endothelial cells: is smoking reduced or nicotine-free products really safe?
      Authors: Naik, Pooja, Fofaria, Neel, Prasad, Shikha, Sajja, Ravi K, Weksler, Babette, Couraud, Pierre-O, Romero, Ignacio, Cucullo, Luca
      BMC Neurosci, 2014;15(0):51.
      Species: Human
      Sample Type: Cell Culture Supernates
    92. Early B cell factor 1 regulates adipocyte morphology and lipolysis in white adipose tissue.
      Authors: Gao H, Mejhert N, Fretz J, Arner E, Lorente-Cebrian S, Ehrlund A, Dahlman-Wright K, Gong X, Stromblad S, Douagi I, Laurencikiene J, Dahlman I, Daub C, Ryden M, Horowitz M, Arner P
      Cell Metab, 2014;19(6):981-92.
      Species: Human
      Sample Type: Cell Culture Supernates
    93. Blood stem cell fate regulation by Delta-1-mediated rewiring of IL-6 paracrine signaling.
      Authors: Csaszar, Elizabet, Wang, Weijia, Usenko, Tatiana, Qiao, Wenlian, Delaney, Colleen, Bernstein, Irwin D, Zandstra, Peter W
      Blood, 2014;123(5):650-8.
      Species: Human
      Sample Type: Cell Culture Supernates
    94. Endocannabinoids affect innate immunity of Muller glia during HIV-1 Tat cytotoxicity.
      Authors: Krishnan G, Chatterjee N
      Mol Cell Neurosci, 2014;59(0):10-23.
      Species: Human
      Sample Type: Cell Culture Supernates
    95. Increased pericyte coverage mediated by endothelial-derived fibroblast growth factor-2 and interleukin-6 is a source of smooth muscle-like cells in pulmonary hypertension.
      Authors: Ricard N, Tu L, Le Hiress M, Huertas A, Phan C, Thuillet R, Sattler C, Fadel E, Seferian A, Montani D, Dorfmuller P, Humbert M, Guignabert C
      Circulation, 2014;129(15):1586-97.
      Species: Human
      Sample Type: Cell Culture Supernates
    96. Effect of Sfrp5 on cytokine release and insulin action in primary human adipocytes and skeletal muscle cells.
      Authors: Carstensen M, Wiza C, Rohrig K, Fahlbusch P, Roden M, Herder C, Ouwens D
      PLoS ONE, 2014;9(1):e85906.
      Species: Human
      Sample Type: Cell Culture Supernates
    97. Coinfection with human herpesvirus 8 is associated with persistent inflammation and immune activation in virologically suppressed HIV-infected patients.
      Authors: Masia M, Robledano C, Ortiz de la Tabla V, Antequera P, Lumbreras B, Hernandez I, Gutierrez F
      PLoS ONE, 2014;9(8):e105442.
      Species: Human
      Sample Type: Plasma
    98. Mycobacteria bypass mucosal NF-kB signalling to induce an epithelial anti-inflammatory IL-22 and IL-10 response.
      Authors: Lutay N, Hakansson G, Alaridah N, Hallgren O, Westergren-Thorsson G, Godaly G
      PLoS ONE, 2014;9(1):e86466.
      Species: Human
      Sample Type: Cell Culture Supernates
    99. Immune-inflammatory markers and arterial stiffness indexes in subjects with acute ischemic stroke with and without metabolic syndrome.
      Authors: Tuttolomondo A, Pecoraro R, Di Raimondo D, Di Sciacca R, Canino B, Arnao V, Butta C, Della Corte V, Maida C, Licata G, Pinto A
      Diabetol Metab Syndr, 2014;6(1):28.
      Species: Human
      Sample Type: Plasma
    100. From a traditional medicinal plant to a rational drug: understanding the clinically proven wound healing efficacy of birch bark extract.
      Authors: Ebeling, Sandra, Naumann, Katrin, Pollok, Simone, Wardecki, Tina, Vidal-Y-Sy, Sabine, Nascimento, Juliana, Boerries, Melanie, Schmidt, Gudula, Brandner, Johanna, Merfort, Irmgard
      PLoS ONE, 2014;9(1):e86147.
      Species: Human
      Sample Type: Cell Culture Supernates
    101. Circulating levels of tumor necrosis factor-alpha receptor 2 are increased in heart failure with preserved ejection fraction relative to heart failure with reduced ejection fraction: evidence for a divergence in pathophysiology.
      Authors: Putko B, Wang Z, Lo J, Anderson T, Becher H, Dyck J, Kassiri Z, Oudit G
      PLoS ONE, 2014;9(6):e99495.
      Species: Human
      Sample Type: Plasma
    102. HAVCR/KIM-1 activates the IL-6/STAT-3 pathway in clear cell renal cell carcinoma and determines tumor progression and patient outcome.
      Authors: Cuadros T, Trilla E, Sarro E, Vila M, Vilardell J, de Torres I, Salcedo M, Lopez-Hellin J, Sanchez A, Ramon y Cajal S, Itarte E, Morote J, Meseguer A
      Cancer Res, 2014;74(5):1416-28.
      Species: Human
      Sample Type: Cell Culture Supernates
    103. Regional adipose tissue hormone/cytokine production before and after weight loss in abdominally obese women.
      Authors: You T, Wang X, Murphy K, Lyles M, Demons J, Yang R, Gong D, Nicklas B
      Obesity (Silver Spring), 2014;22(7):1679-84.
      Species: Human
      Sample Type: Plasma
    104. Differences in PGE2 production between primary human monocytes and differentiated macrophages: role of IL-1beta and TRIF/IRF3.
      Authors: Endo Y, Blinova K, Romantseva T, Golding H, Zaitseva M
      PLoS ONE, 2014;9(5):e98517.
      Species: Human
      Sample Type: Cell Culture Supernates
    105. Expression of suppressor of cytokine signaling 3 in cerebrospinal fluid after subarachnoid hemorrhage.
      Authors: Osuka, Koji, Watanabe, Yasuo, Aoyama, Masahiro, Nakura, Takahiro, Matsuo, Naoki, Takayasu, Masakazu
      J Neuroinflammation, 2014;11(0):142.
      Species: Human
      Sample Type: CSF
    106. IL-6-174 G > C and MMP-9-1562 C > T polymorphisms are associated with increased risk of deep vein thrombosis in cancer patients.
      Authors: Malaponte G, Polesel J, Candido S, Sambataro D, Bevelacqua V, Anzaldi M, Vella N, Fiore V, Militello L, Mazzarino M, Libra M, Signorelli S
      Cytokine, 2013;62(1):64-9.
      Species: Human
      Sample Type: Plasma
    107. Reference range and short- and long-term biological variation of interleukin (IL)-6, IL-17A and tissue necrosis factor-alpha using high sensitivity assays.
      Authors: Todd J, Simpson P, Estis J, Torres V, Wub A
      Cytokine, 2013;64(3):660-5.
      Species: Human
      Sample Type: Plasma
    108. Role of the functional Toll-Like receptor-9 promoter polymorphism (-1237T/C) in increased risk of end-stage renal disease: a case-control study.
      Authors: Yang, Hsin-Yi, Lu, Kuo-Chen, Lee, Herng-Sh, Huang, Shih-Min, Lin, Yuh-Feng, Wu, Chia-Cha, Salter, Donald M, Su, Sui-Lung
      PLoS ONE, 2013;8(3):e58444.
      Species: Human
      Sample Type: Cell Culture Supernates
    109. STAT3 interacts with Skp2/p27/p21 pathway to regulate the motility and invasion of gastric cancer cells.
      Authors: Wei Z, Jiang X, Qiao H, Zhai B, Zhang L, Zhang Q, Wu Y, Jiang H, Sun X
      Cell Signal, 2013;25(4):931-8.
      Species: Human
      Sample Type: Cell Culture Supernates
    110. Protein carbamylation predicts mortality in ESRD.
      Authors: Koeth R, Kalantar-Zadeh K, Wang Z, Fu X, Tang W, Hazen S
      , 2013;0(0):.
      Species: Human
      Sample Type: Serum
    111. The systemic cytokine environment is permanently altered in multiple myeloma.
      Authors: Zheng M, Zhang Z, Bemis K, Belch A, Pilarski L, Shively J, Kirshner J
      PLoS ONE, 2013;8(3):e58504.
    112. Decreased IL-7 responsiveness is related to oxidative stress in HIV disease.
      Authors: Kalinowska M, Bazdar D, Lederman M, Funderburg N, Sieg S
      PLoS ONE, 2013;8(3):e58764.
      Species: Human
      Sample Type: Serum
    113. Reduced BMPR2 expression induces GM-CSF translation and macrophage recruitment in humans and mice to exacerbate pulmonary hypertension.
      Authors: Sawada H, Saito T, Nickel N, Alastalo T, Glotzbach J, Chan R, Haghighat L, Fuchs G, Januszyk M, Cao A, Lai Y, Perez V, Kim Y, Wang L, Chen P, Spiekerkoetter E, Mitani Y, Gurtner G, Sarnow P, Rabinovitch M
      J Exp Med, 2013;211(2):263-80.
      Species: Human
      Sample Type: Cell Culture Supernates
    114. EGFR inhibition induces proinflammatory cytokines via NOX4 in HNSCC.
      Authors: Fletcher E, Love-Homan L, Sobhakumari A, Feddersen C, Koch A, Goel A, Simons A
      Mol Cancer Res, 2013;11(12):1574-84.
      Species: Human
      Sample Type: Cell Culture Supernates
    115. Evidences of early senescence in multiple myeloma bone marrow mesenchymal stromal cells.
      Authors: Andre T, Meuleman N, Stamatopoulos B, De Bruyn C, Pieters K, Bron D, Lagneaux L
      PLoS ONE, 2013;8(3):e59756.
      Species: Human
      Sample Type: Cell Culture Supernates
    116. HCMV activates the IL-6-JAK-STAT3 axis in HepG2 cells and primary human hepatocytes.
      Authors: Lepiller Q, Abbas W, Kumar A, Tripathy M, Herbein G
      PLoS ONE, 2013;8(3):e59591.
      Species: Human
      Sample Type: Cell Culture Supernates
    117. Cleaved/associated TLR3 represents the primary form of the signaling receptor.
      Authors: Toscano F, Estornes Y, Virard F, Garcia-Cattaneo A, Pierrot A, Vanbervliet B, Bonnin M, Ciancanelli M, Zhang S, Funami K, Seya T, Matsumoto M, Pin J, Casanova J, Renno T, Lebecque S
      J Immunol, 2013;190(2):764-73.
      Species: Human
      Sample Type: Cell Culture Supernates
    118. Inflammation marker and risk of pancreatic cancer: a nested case-control study within the EPIC cohort.
      Authors: Grote VA, Kaaks R, Nieters A, Tjonneland A, Halkjaer J, Overvad K, Skjelbo Nielsen MR, Boutron-Ruault MC, Clavel-Chapelon F, Racine A, Teucher B, Becker S, Pischon T, Boeing H, Trichopoulou A, Cassapa C, Stratigakou V, Palli D, Krogh V, Tumino R, Vineis P, Panico S, Rodriguez L, Duell EJ, Sanchez MJ, Dorronsoro M, Navarro C, Gurrea AB, Siersema PD, Peeters PH, Ye W, Sund M, Lindkvist B, Johansen D, Khaw KT, Wareham N, Allen NE, Travis RC, Fedirko V, Jenab M, Michaud DS, Chuang SC, Romaguera D, Bueno-de-Mesquita HB, Rohrmann S
      Br. J. Cancer, 2012;106(11):1866-74.
      Species: Human
      Sample Type: Plasma
    119. Engulfment of hematopoietic stem cells caused by down-regulation of CD47 is critical in the pathogenesis of hemophagocytic lymphohistiocytosis.
      Authors: Kuriyama T, Takenaka K, Kohno K, Yamauchi T, Daitoku S, Yoshimoto G, Kikushige Y, Kishimoto J, Abe Y, Harada N, Miyamoto T, Iwasaki H, Teshima T, Akashi K
      Blood, 2012;120(19):4058-67.
      Species: Human
      Sample Type: Serum
    120. Opium addiction increases interleukin 1 receptor antagonist (IL-1Ra) in the coronary artery disease patients.
      Authors: Saadat, Habiboll, Ziai, Seyed Al, Ghanemnia, Maryam, Namazi, Mohammad, Safi, Morteza, Vakili, Hosein, Dabbagh, Ali, Gholami, Omid
      PLoS ONE, 2012;7(9):e44939.
      Species: Human
      Sample Type: Plasma
    121. Mycobacterium bovis bacilli Calmette-Guerin regulates leukocyte recruitment by modulating alveolar inflammatory responses.
      Authors: Andersson M, Lutay N, Hallgren O, Westergren-Thorsson G, Svensson M, Godaly G
      Innate Immun, 2012;18(3):531-40.
      Species: Human
      Sample Type: Cell Culture Supernates
    122. A galectin-3-dependent pathway upregulates interleukin-6 in the microenvironment of human neuroblastoma.
      Authors: Silverman A, Nakata R, Shimada H, Sposto R, DeClerck Y
      Cancer Res, 2012;72(9):2228-38.
      Species: Human
      Sample Type: Cell Culture Supernates
    123. TBK1-associated protein in endolysosomes (TAPE)/CC2D1A is a key regulator linking RIG-I-like receptors to antiviral immunity.
      Authors: Chen K, Chang C, Huang C, Lin C, Lin W, Lo Y, Yang C, Hsing E, Chen L, Shih S, Shiau A, Lei H, Tan T, Ling P
      J Biol Chem, 2012;287(38):32216-21.
      Species: Mouse
      Sample Type: Cell Culture Supernates
    124. Stimulated in vivo synthesis of plasminogen activator inhibitor-1 in human adipose tissue.
      Authors: Ekstrom M, Liska J, Eriksson P, Sverremark-Ekstrom E, Tornvall P
      Thromb Haemost, 2012;108(3):485-92.
      Species: Human
      Sample Type: Plasma
    125. A randomized trial of recombinant human granulocyte-macrophage colony stimulating factor for patients with acute lung injury.
      Authors: Paine R, Standiford TJ, Dechert RE, Moss M, Martin GS, Rosenberg AL, Thannickal VJ, Burnham EL, Brown MB, Hyzy RC
      Crit. Care Med., 2012;40(1):90-7.
      Species: Human
      Sample Type: BALF
    126. Anti-arthritic effects of magnolol in human interleukin 1β-stimulated fibroblast-like synoviocytes and in a rat arthritis model.
      Authors: Wang JH, Shih KS, Liou JP, Wu YW, Chang AS, Wang KL, Tsai CL, Yang CR
      PLoS ONE, 2012;7(2):e31368.
      Species: Human
      Sample Type: Cell Culture Supernates
    127. Adiponectin induces CCL20 expression synergistically with IL-6 and TNF-alpha in THP-1 macrophages.
      Authors: Suzuki M, Mihara M
      Cytokine, 2012;58(3):344-50.
      Species: Human
      Sample Type: Cell Culture Supernates
    128. A dynamic inflammatory cytokine network in the human ovarian cancer microenvironment.
      Authors: Kulbe H, Chakravarty P, Leinster DA, Charles KA, Kwong J, Thompson RG, Coward JI, Schioppa T, Robinson SC, Gallagher WM, Galletta L, Salako MA, Smyth JF, Hagemann T, Brennan DJ, Bowtell DD, Balkwill FR
      Cancer Res., 2012;72(1):66-75.
      Species: Human
      Sample Type: Cell Culture Supernates
    129. Validation and quality control of ELISAs for the use with human saliva samples.
      Authors: Jaedicke KM, Taylor JJ, Preshaw PM
      J. Immunol. Methods, 2012;377(1):62-5.
      Species: Human
      Sample Type: Saliva
    130. CD4 T follicular helper cell dynamics during SIV infection.
      J. Clin. Invest., 2012;122(9):3281-94.
      Species: Primate - Macaca mulatta (Rhesus Macaque)
      Sample Type: Plasma
    131. Compensated inflammation in systemic juvenile idiopathic arthritis: role of alternatively activated macrophages.
      Authors: Shimizu M, Yachie A
      Cytokine, 2012;60(1):226-32.
      Species: Human
      Sample Type: Serum
    132. IL-33 promotes the migration and proliferation of circulating fibrocytes from patients with allergen-exacerbated asthma.
      Authors: Bianchetti L, Marini M, Isgro M, Bellini A, Schmidt M, Mattoli S
      Biochem Biophys Res Commun, 2012;426(1):116-21.
      Species: Human
      Sample Type: Cell Culture Supernates
    133. Cytomegalovirus impairs cytotrophoblast-induced lymphangiogenesis and vascular remodeling in an in vivo human placentation model.
      Authors: Tabata T, Petitt M, Fang-Hoover J, Rivera J, Nozawa N, Shiboski S, Inoue N, Pereira L
      Am J Pathol, 2012;181(5):1540-59.
      Species: Human
      Sample Type: Cell Culture Supernates
    134. p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype.
      Authors: Freund A, Patil CK, Campisi J
      EMBO J., 2011;30(8):1536-48.
      Species: Human
      Sample Type: Cell Culture Supernates
    135. HDAC inhibition by LBH589 affects the phenotype and function of human myeloid dendritic cells.
      Authors: Song W, Tai YT, Tian Z, Hideshima T, Chauhan D, Nanjappa P, Exley MA, Anderson KC, Munshi NC
      Leukemia, 2011;25(1):161-8.
      Species: Human
      Sample Type: Cell Culture Supernates
    136. Kinetics of circulating Th17 cytokines and adipokines in psoriasis patients.
      Authors: Nakajima H, Nakajima K, Tarutani M, Morishige R, Sano S
      Arch. Dermatol. Res., 2011;303(6):451-5.
      Species: Human
      Sample Type: Serum
    137. Cyclooxygenase-2 inhibitor blocks the production of West Nile virus-induced neuroinflammatory markers in astrocytes.
      Authors: Verma S, Kumar M, Nerurkar VR
      J. Gen. Virol., 2011;92(0):507-15.
      Species: Human
      Sample Type: Cell Culture Supernates
    138. Curcumin treatment suppresses IKKbeta kinase activity of salivary cells of patients with head and neck cancer: a pilot study.
      Authors: Kim SG, Veena MS, Basak SK, Han E, Tajima T, Gjertson DW, Starr J, Eidelman O, Pollard HB, Srivastava M, Srivatsan ES, Wang MB
      Clin. Cancer Res., 2011;17(18):5953-61.
      Species: Human
      Sample Type: Saliva
    139. Increased prevalence of albuminuria in HIV-infected adults with diabetes.
      Authors: Kim PS, Woods C, Dutcher L, Georgoff P, Rosenberg A, Mican JA, Kopp JB, Smith MA, Hadigan C
      PLoS ONE, 2011;6(9):e24610.
      Species: Human
      Sample Type: Serum
    140. Upregulation of lipocalin 2 in adipose tissues of severely obese women: positive relationship with proinflammatory cytokines.
      Authors: Auguet T, Quintero Y, Terra X, Martinez S, Lucas A, Pellitero S, Aguilar C, Hernandez M, Del Castillo D, Richart C
      Obesity (Silver Spring), 2011;19(12):2295-300.
      Species: Human
      Sample Type: Serum
    141. Inflammation associated with obesity: relationship with blood and bone marrow endothelial cells.
      Authors: McGuire TR, Brusnahan SK, Bilek LD, Jackson JD, Kessinger MA, Berger AM, Garvin KL, O'Kane BJ, Tuljapurkar SR, Sharp JG
      Obesity (Silver Spring), 2011;19(11):2130-6.
      Species: Human
      Sample Type: Plasma
    142. Exenatide affects circulating cardiovascular risk biomarkers independently of changes in body composition.
      Authors: Bunck MC, Diamant M, Eliasson B, Corner A, Shaginian RM, Heine RJ, Taskinen MR, Yki-Jarvinen H, Smith U
      Diabetes Care, 2010;33(8):1734-7.
      Species: Human
      Sample Type: Serum
    143. Presence of IL-5 protein and IgE antibodies to staphylococcal enterotoxins in nasal polyps is associated with comorbid asthma.
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      J. Allergy Clin. Immunol., 2010;126(5):962.
      Species: Human
      Sample Type: Tissue Homogenates
    144. Serum IP-10 as a biomarker of human rhinovirus infection at exacerbation of COPD.
      Authors: Quint JK, Donaldson GC, Goldring JJ, Baghai-Ravary R, Hurst JR, Wedzicha JA
      Chest, 2010;137(4):812-22.
      Species: Human
      Sample Type: Serum
    145. Phagocytosis of apoptotic cells modulates mesenchymal stem cells osteogenic differentiation to enhance IL-17 and RANKL expression on CD4+ T cells.
      Authors: Tso GH, Law HK, Tu W
      Stem Cells, 2010;28(5):939-54.
      Species: Human
      Sample Type: Cell Culture Supernates
    146. IL-33 mediates inflammatory responses in human lung tissue cells.
      Authors: Yagami A, Orihara K, Morita H
      J. Immunol., 2010;185(10):5743-50.
      Species: Human
      Sample Type: Cell Culture Supernates
    147. Prehospital resuscitation with hypertonic saline-dextran modulates inflammatory, coagulation and endothelial activation marker profiles in severe traumatic brain injured patients.
      Authors: Rhind SG, Crnko NT, Baker AJ
      J Neuroinflammation, 2010;7(0):5.
      Species: Human
      Sample Type: Serum
    148. The novel lipopolysaccharide-binding protein CRISPLD2 is a critical serum protein to regulate endotoxin function.
      Authors: Wang ZQ, Xing WM, Fan HH, Wang KS, Zhang HK, Wang QW, Qi J, Yang HM, Yang J, Ren YN, Cui SJ, Zhang X, Liu F, Lin DH, Wang WH, Hoffmann MK, Han ZG
      J. Immunol., 2009;183(10):6646-56.
      Species: Human
      Sample Type: Cell Culture Supernates
    149. Gender specific associations between matrix metalloproteinases and inflammatory markers in post myocardial infarction patients.
      Authors: Samnegard A, Hulthe J, Silveira A, Ericsson CG, Hamsten A, Eriksson P
      Atherosclerosis, 2009;202(2):550-6.
      Species: Human
      Sample Type: Plasma
    150. Adiponectin upregulates monocytic activin A but systemic levels are not altered in obesity or type 2 diabetes.
      Authors: Weigert J, Neumeier M, Wanninger J, Schober F, Sporrer D, Weber M, Schramm A, Wurm S, Stogbauer F, Filarsky M, Schaffler A, Aslanidis C, Scholmerich J, Buechler C
      Cytokine, 2009;45(2):86-91.
      Species: Human
      Sample Type: Plasma
    151. Decoy receptor 3 levels in peripheral blood predict outcomes of acute respiratory distress syndrome.
      Authors: Chen CY, Yang KY, Chen MY, Chen HY, Lin MT, Lee YC, Perng RP, Hsieh SL, Yang PC, Chou TY
      Am. J. Respir. Crit. Care Med., 2009;180(8):751-60.
      Species: Human
      Sample Type: Plasma
    152. Proteinase-activated receptor (PAR)-2 activation impacts bone resorptive properties of human osteoarthritic subchondral bone osteoblasts.
      Authors: Amiable N, Tat SK, Lajeunesse D, Duval N, Pelletier JP, Martel-Pelletier J, Boileau C
      Bone, 2009;44(6):1143-50.
      Species: Human
      Sample Type: Cell Culture Supernates
    153. Direct and indirect impairment of human dendritic cell function by virulent Francisella tularensis Schu S4.
      Authors: Chase JC, Celli J, Bosio CM
      Infect. Immun., 2009;77(1):180-95.
      Species: Human
      Sample Type: Cell Culture Supernates
    154. Immunomodulation of nasal epithelial cells by Staphylococcus aureus-derived serine proteases.
      Authors: Rudack C, Sachse F, Albert N, Becker K, von Eiff C
      J. Immunol., 2009;183(11):7592-601.
      Species: Human
      Sample Type: Cell Culture Supernates
    155. Inflammatory interaction between LIGHT and proteinase-activated receptor-2 in endothelial cells: potential role in atherogenesis.
      Authors: Sandberg WJ, Halvorsen B, Yndestad A, Smith C, Otterdal K, Brosstad FR, Froland SS, Olofsson PS, Damas JK, Gullestad L, Hansson GK, Oie E, Aukrust P
      Circ. Res., 2009;104(1):60-8.
      Species: Human
      Sample Type: Cell Culture Supernates
    156. In vivo regulation of interleukin 1beta in patients with cryopyrin-associated periodic syndromes.
      Authors: Lachmann HJ, Lowe P, Felix SD, Rordorf C, Leslie K, Madhoo S, Wittkowski H, Bek S, Hartmann N, Bosset S, Hawkins PN, Jung T
      J. Exp. Med., 2009;206(5):1029-36.
      Species: Human
      Sample Type: Plasma
    157. Cytokine secretion by human mesenchymal stem cells cocultured with damaged corneal epithelial cells.
      Authors: Oh JY, Kim MK, Shin MS, Wee WR, Lee JH
      Cytokine, 2009;46(1):100-3.
      Species: Human
      Sample Type: Cell Culture Supernates
    158. Immuno-inflammatory and thrombotic/fibrinolytic variables associated with acute ischemic stroke diagnosis.
      Authors: Tuttolomondo A, Pinto A, Corrao S, Di Raimondo D, Fernandez P, Di Sciacca R, Arnao V, Licata G
      Atherosclerosis, 2009;203(2):503-8.
      Species: Human
      Sample Type: Plasma
    159. HIV increases markers of cardiovascular risk: results from a randomized, treatment interruption trial.
      Authors: Calmy A, Gayet-Ageron A, Montecucco F, Nguyen A, Mach F, Burger F, Ubolyam S, Carr A, Ruxungtham K, Hirschel B, Ananworanich J,
      AIDS, 2009;23(8):929-39.
      Species: Human
      Sample Type: Plasma
    160. Interleukin-6 in the bone marrow microenvironment promotes the growth and survival of neuroblastoma cells.
      Authors: Ara T, Song L, Shimada H, Keshelava N, Russell HV, Metelitsa LS, Groshen SG, Seeger RC, DeClerck YA
      Cancer Res., 2009;69(1):329-37.
      Species: Human
      Sample Type: Serum
    161. Dexamethasone suppresses interleukin-22 associated with bacterial infection in vitro and in vivo.
      Authors: Ziesche E, Scheiermann P, Bachmann M, Sadik CD, Hofstetter C, Zwissler B, Pfeilschifter J, Muhl H
      Clin. Exp. Immunol., 2009;157(3):370-6.
      Species: Human
      Sample Type: Plasma
    162. Smoking, inflammatory patterns and postprandial hypertriglyceridemia.
      Authors: Kabagambe EK, Ordovas JM, Tsai MY, Borecki IB, Hopkins PN, Glasser SP, Arnett DK
      Atherosclerosis, 2009;203(2):633-9.
      Species: Human
      Sample Type: Serum
    163. Interleukin-32 promotes osteoclast differentiation but not osteoclast activation.
      Authors: Mabilleau G, Sabokbar A
      PLoS ONE, 2009;4(1):e4173.
      Species: Human
      Sample Type: Cell Culture Supernates
    164. Time course of anemia during six months follow up following intensive care discharge and factors associated with impaired recovery of erythropoiesis.
      Authors: Bateman AP, McArdle F, Walsh TS
      Crit. Care Med., 2009;37(6):1906-12.
      Species: Human
      Sample Type: Serum
    165. Prostate cancer promotes CD11b positive cells to differentiate into osteoclasts.
      Authors: Mizutani K, Sud S, Pienta KJ
      J. Cell. Biochem., 2009;106(4):563-9.
      Species: Human
      Sample Type: Cell Culture Supernates
    166. Cerebrospinal fluid levels of interleukin-6 and interleukin-12 in children with meningitis.
      Authors: Hsieh CC, Lu JH, Chen SJ, Lan CC, Chow WC, Tang RB
      Cytotechnology, 2009;25(4):461-5.
      Species: Human
      Sample Type: CSF
    167. Soluble and membrane levels of molecules involved in the interaction between clonal plasma cells and the immunological microenvironment in multiple myeloma and their association with the characteristics of the disease.
      Authors: Perez-Andres M, Almeida J, Martin-Ayuso M, De Las Heras N, Moro MJ, Martin-Nunez G, Galende J, Cuello R, Abuin I, Moreno I, Dominguez M, Hernandez J, Mateo G, San Miguel JF, Orfao A
      Int. J. Cancer, 2009;124(2):367-75.
      Species: Human
      Sample Type: Plasma
    168. Helicobacter pylori cytotoxin-associated gene A activates the signal transducer and activator of transcription 3 pathway in vitro and in vivo.
      Authors: Bronte-Tinkew DM, Terebiznik M, Franco A, Ang M, Ahn D, Mimuro H, Sasakawa C, Ropeleski MJ, Peek RM, Jones NL
      Cancer Res., 2009;69(2):632-9.
      Species: Human
      Sample Type: Cell Culture Supernates
    169. HLA-DR+ leukocytes acquire CD1 antigens in embryonic and fetal human skin and contain functional antigen-presenting cells.
      Authors: Schuster C, Vaculik C, Fiala C, Meindl S, Brandt O, Imhof M, Stingl G, Eppel W, Elbe-Burger A
      J. Exp. Med., 2009;206(1):169-81.
      Species: Human
      Sample Type: Cell Culture Supernates
    170. Low-grade inflammation can partly explain the association between the metabolic syndrome and either coronary artery disease or severity of peripheral arterial disease: the CODAM study.
      Authors: Jacobs M, van Greevenbroek MM, van der Kallen CJ, Ferreira I, Blaak EE, Feskens EJ, Jansen EH, Schalkwijk CG, Stehouwer CD
      Eur. J. Clin. Invest., 2009;39(6):437-44.
      Species: Human
      Sample Type: Plasma
    171. Urinary proinflammatory cytokine response in renal transplant recipients with polyomavirus BK viruria.
      Authors: Sadeghi M, Daniel V, Schnitzler P, Lahdou I, Naujokat C, Zeier M, Opelz G
      Transplantation, 2009;88(9):1109-16.
      Species: Human
      Sample Type: Urine
    172. Two large preoperative doses of erythropoietin do not reduce the systemic inflammatory response to cardiac surgery.
      Authors: Poulsen TD, Andersen LW, Steinbruchel D, Gotze JP, Jorgensen OS, Olsen NV
      J. Cardiothorac. Vasc. Anesth., 2009;23(3):316-23.
      Species: Human
      Sample Type: Plasma
    173. Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion.
      Authors: Rodier F, Coppe JP, Patil CK, Hoeijmakers WA, Munoz DP, Raza SR, Freund A, Campeau E, Davalos AR, Campisi J
      Nat. Cell Biol., 2009;11(8):973-9.
      Species: Human
      Sample Type: Cell Culture Supernates
    174. Functional coexpression of Interleukin (IL)-7 and its receptor (IL-7R) on Hodgkin and Reed-Sternberg cells: Involvement of IL-7 in tumor cell growth and microenvironmental interactions of Hodgkin's lymphoma.
      Authors: Cattaruzza L, Gloghini A, Olivo K, Di Francia R, Lorenzon D, De Filippi R, Carbone A, Colombatti A, Pinto A, Aldinucci D
      Int. J. Cancer, 2009;125(5):1092-101.
      Species: Human
      Sample Type: Cell Culture Supernates
    175. Hyperbaric oxygen causes both antiinflammation and antipyresis in rabbits.
      Authors: Niu KC, Huang WT, Lin MT, Huang KF
      Eur. J. Pharmacol., 2009;606(1):240-5.
      Species: Rabbit
      Sample Type: Serum
    176. NF-kappaB-dependent cytokines in saliva and serum from patients with oral lichen planus: a study in an ethnic Chinese population.
      Authors: Zhang Y, Lin M, Zhang S, Wang Z, Jiang L, Shen J, Bai J, Gao F, Zhou M, Chen Q
      Cytokine, 2008;41(2):144-9.
      Species: Human
      Sample Type: Serum
    177. Autologous antitumor activity by NK cells expanded from myeloma patients using GMP-compliant components.
      Authors: Alici E, Sutlu T, Bjorkstrand B, Gilljam M, Stellan B, Nahi H, Quezada HC, Gahrton G, Ljunggren HG, Dilber MS
      Blood, 2008;111(6):3155-62.
      Species: Human
      Sample Type: Cell Culture Supernates
    178. Assessment of cervicovaginal cytokine levels following exposure to microbicide Nisin gel in rabbits.
      Authors: Aranha CC, Gupta SM, Reddy KV
      Cytokine, 2008;43(1):63-70.
      Species: Rabbit
      Sample Type: Cell Culture Supernates
    179. Gene expression profiling of human skeletal muscle in response to stabilized weight loss.
      Authors: Larrouy D, Barbe P, Valle C, Dejean S, Pelloux V, Thalamas C, Bastard JP, Le Bouil A, Diquet B, Clement K, Langin D, Viguerie N
      Am. J. Clin. Nutr., 2008;88(1):125-32.
      Species: Human
      Sample Type: Plasma
    180. Biological and technical variables affecting immunoassay recovery of cytokines from human serum and simulated vaginal fluid: a multicenter study.
      Authors: Fichorova RN, Richardson-Harman N, Alfano M, Belec L, Carbonneil C, Chen S, Cosentino L, Curtis K, Dezzutti CS, Donoval B, Doncel GF, Donaghay M, Grivel JC, Guzman E, Hayes M, Herold B, Hillier S, Lackman-Smith C, Landay A, Margolis L, Mayer KH, Pasicznyk JM, Pallansch-Cokonis M, Poli G, Reichelderfer P, Roberts P, Rodriguez I, Saidi H, Sassi RR, Shattock R, Cummins JE
      Anal. Chem., 2008;80(12):4741-51.
      Species: Human
      Sample Type: Reference Standard
    181. Improved prediction of disease relapse after radical prostatectomy through a panel of preoperative blood-based biomarkers.
      Authors: Shariat SF, Karam JA, Walz J, Roehrborn CG, Montorsi F, Margulis V, Saad F, Slawin KM, Karakiewicz PI
      Clin. Cancer Res., 2008;14(12):3785-91.
      Species: Human
      Sample Type: Plasma
    182. Hypoxia induces leptin gene expression and secretion in human preadipocytes: differential effects of hypoxia on adipokine expression by preadipocytes.
      Authors: Wang B, Wood IS, Trayhurn P
      J. Endocrinol., 2008;198(1):127-34.
      Species: Human
      Sample Type: Cell Culture Supernates
    183. Pharmacodynamics and Pharmacokinetics of the Novel Thrombopoietin Mimetic Peptide RWJ-800088 in Humans.
      Authors: Liem-Moolenaar M, Cerneus D, Molloy C, End D, Brown K, de Kam M, Cohen A, van Hensbergen Y, Burggraaf J
      2008;84(0):481.
      Species: Human
      Sample Type: Plasma
    184. In vivo transmigrated monocytes from patients with stable coronary artery disease have a reduced expression of CD11b.
      Authors: Paulsson JM, Dadfar E, Held C, Jacobson SH, Lundahl J
      Clin. Exp. Immunol., 2008;153(2):196-204.
      Species: Human
      Sample Type: Blister Fluid
    185. MMP-12 induces IL-8/CXCL8 secretion through EGFR and ERK1/2 activation in epithelial cells.
      Authors: Le Quement C, Guenon I, Gillon JY, Lagente V, Boichot E
      Am. J. Physiol. Lung Cell Mol. Physiol., 2008;294(6):L1076-84.
      Species: Human
      Sample Type: Cell Culture Supernates
    186. Human airway smooth muscle promotes human lung mast cell survival, proliferation, and constitutive activation: cooperative roles for CADM1, stem cell factor, and IL-6.
      Authors: Hollins F, Kaur D, Yang W, Cruse G, Saunders R, Sutcliffe A, Berger P, Ito A, Brightling CE, Bradding P
      J. Immunol., 2008;181(4):2772-80.
      Species: Human
      Sample Type: Cell Culture Supernates
    187. Short communication: decreasing soluble CD30 and increasing IFN-gamma plasma levels are indicators of effective highly active antiretroviral therapy.
      Authors: Sadeghi M, Susal C, Daniel V, Naujokat C, Zimmermann R, Huth-Kuhne A, Opelz G
      AIDS Res. Hum. Retroviruses, 2007;23(7):886-90.
      Species: Human
      Sample Type: Plasma
    188. Interaction between cytokines and sCD40L in patients with stable and unstable coronary syndromes.
      Authors: Tousoulis D, Antoniades C, Nikolopoulou A, Koniari K, Vasiliadou C, Marinou K, Koumallos N, Papageorgiou N, Stefanadi E, Siasos G, Stefanadis C
      Eur. J. Clin. Invest., 2007;37(8):623-8.
      Species: Human
      Sample Type: Serum
    189. Mesenchymal stem cell abnormalities in patients with multiple myeloma.
      Authors: Garderet L, Mazurier C, Chapel A, Ernou I, Boutin L, Holy X, Gorin NC, Lopez M, Doucet C, Lataillade JJ
      Leuk. Lymphoma, 2007;48(10):2032-41.
      Species: Human
      Sample Type: Cell Culture Supernates
    190. Nitrosative stress predicts the presence and severity of nonalcoholic fatty liver at different stages of the development of insulin resistance and metabolic syndrome: possible role of vitamin A intake.
      Authors: Musso G, Gambino R, De Michieli F, Biroli G, Premoli A, Pagano G, Bo S, Durazzo M, Cassader M
      Am. J. Clin. Nutr., 2007;86(3):661-71.
      Species: Human
      Sample Type: Serum
    191. 1, 25 Dihydroxyvitamin D3 modulated cytokine response in pulmonary tuberculosis.
      Authors: Vidyarani M, Selvaraj P, Jawahar MS, Narayanan PR
      Cytokine, 2007;40(2):128-34.
      Species: Human
      Sample Type: Cell Culture Supernates
    192. Pilot study of rosiglitazone therapy in women with breast cancer: effects of short-term therapy on tumor tissue and serum markers.
      Authors: Yee LD, Williams N, Wen P, Young DC, Lester J, Johnson MV, Farrar WB, Walker MJ, Povoski SP, Suster S, Eng C
      Clin. Cancer Res., 2007;13(1):246-52.
      Species: Human
      Sample Type: Serum
    193. Interferon-beta and adhesion molecules (E-selectin and s-intracellular adhesion molecule-1) are detected in sera from patients with retinal vasculitis and are induced in retinal vascular endothelial cells by Toll-like receptor 3 signalling.
      Authors: Lee MT, Hooper LC, Kump L, Hayashi K, Nussenblatt R, Hooks JJ, Detrick B
      Clin. Exp. Immunol., 2007;147(1):71-80.
      Species: Human
      Sample Type: Serum
    194. Changes in plasma vascular endothelial growth factor, angiopoietins, and their receptors following surgery for breast cancer.
      Authors: Caine GJ, Stonelake PS, Lip GY, Blann AD
      Cancer Lett., 2007;248(1):131-6.
      Species: Human
      Sample Type: Plasma
    195. Human mesenchymal stem cells inhibit neutrophil apoptosis: a model for neutrophil preservation in the bone marrow niche.
      Authors: Raffaghello L, Bianchi G, Bertolotto M, Montecucco F, Busca A, Dallegri F, Ottonello L, Pistoia V
      Stem Cells, 2007;26(1):151-62.
      Species: Human
      Sample Type: Cell Culture Supernates
    196. Panel of markers can accurately predict endometriosis in a subset of patients.
      Authors: Seeber B, Sammel MD, Fan X, Gerton GL, Shaunik A, Chittams J, Barnhart KT
      Fertil. Steril., 2007;89(5):1073-81.
      Species: Human
      Sample Type: Serum
    197. Newly recruited human monocytes have a preserved responsiveness towards bacterial peptides in terms of CD11b up-regulation and intracellular hydrogen peroxide production.
      Authors: Dadfar E, Jacobson SH, Lundahl J
      Clin. Exp. Immunol., 2007;148(3):573-82.
      Species: Human
      Sample Type: Serum
    198. Inactivated Sendai virus particles eradicate tumors by inducing immune responses through blocking regulatory T cells.
      Authors: Kurooka M, Kaneda Y
      Cancer Res., 2007;67(1):227-36.
      Species: Human
      Sample Type: Cell Culture Supernates
    199. Tumor necrosis factor alpha as a new target for renal cell carcinoma: two sequential phase II trials of infliximab at standard and high dose.
      Authors: Harrison ML, Obermueller E, Maisey NR, Hoare S, Edmonds K, Li NF, Chao D, Hall K, Lee C, Timotheadou E, Charles K, Ahern R, King DM, Eisen T, Corringham R, DeWitte M, Balkwill F, Gore M
      J. Clin. Oncol., 2007;25(29):4542-9.
      Species: Human
      Sample Type: Plasma
    200. Angiopoietin-2 is increased in severe sepsis: correlation with inflammatory mediators.
      Authors: Orfanos SE, Kotanidou A, Glynos C, Athanasiou C, Tsigkos S, Dimopoulou I, Sotiropoulou C, Zakynthinos S, Armaganidis A, Papapetropoulos A, Roussos C
      Crit. Care Med., 2007;35(1):199-206.
      Species: Human
      Sample Type: Serum
    201. Developmental differences in the responses of IL-6 and IL-13 transgenic mice exposed to hyperoxia.
      Authors: Choo-Wing R, Nedrelow JH, Homer RJ, Elias JA, Bhandari V
      Am. J. Physiol. Lung Cell Mol. Physiol., 2007;293(1):L142-50.
      Species: Human
      Sample Type: Tissue Homogenates
    202. Effects of darbepoetin-alpha on plasma pro-inflammatory cytokines, anti-inflammatory cytokine interleukin-10 and soluble Fas/Fas ligand system in anemic patients with chronic heart failure.
      Authors: Kourea K, Parissis JT, Farmakis D, Panou F, Paraskevaidis I, Venetsanou K, Filippatos G, Kremastinos DT
      Atherosclerosis, 2007;199(1):215-21.
      Species: Human
      Sample Type: Plasma
    203. Impairment of human NK cell cytotoxic activity and cytokine release by cigarette smoke.
      Authors: Mian MF, Lauzon NM, Stampfli MR, Mossman KL, Ashkar AA
      J. Leukoc. Biol., 2007;83(3):774-84.
      Species: Human
      Sample Type: Cell Culture Supernates
    204. The levels of steroid hormones and cytokines in individual follicles are not associated with the fertilization outcome after intracytoplasmic sperm injection.
      Authors: Asimakopoulos B, Abu-Hassan D, Metzen E, Al-Hasani S, Diedrich K, Nikolettos N
      Fertil. Steril., 2007;90(1):60-4.
      Species: Human
      Sample Type: Follicular Fluid
    205. Muscle atrophy and hypertrophy signaling in patients with chronic obstructive pulmonary disease.
      Authors: Doucet M, Russell AP, Leger B, Debigare R, Joanisse DR, Caron MA, LeBlanc P, Maltais F
      Am. J. Respir. Crit. Care Med., 2007;176(3):261-9.
      Species: Human
      Sample Type: Plasma
    206. Erythropoiesis abnormalities contribute to early-onset anemia in patients with septic shock.
      Authors: Claessens YE, Fontenay M, Pene F, Chiche JD, Guesnu M, Hababou C, Casadevall N, Dhainaut JF, Mira JP, Cariou A
      Am. J. Respir. Crit. Care Med., 2006;174(1):51-7.
      Species: Human
      Sample Type: Plasma
    207. No difference in the effects of clopidogrel and aspirin on inflammatory markers in patients with coronary heart disease.
      Authors: Solheim S, Pettersen AA, Arnesen H, Seljeflot I
      Thromb. Haemost., 2006;96(5):660-4.
      Species: Human
      Sample Type: Serum
    208. Glycerol monolaurate inhibits the effects of Gram-positive select agents on eukaryotic cells.
      Authors: Peterson ML, Schlievert PM
      Biochemistry, 2006;45(7):2387-97.
      Species: Human
      Sample Type: Cell Culture Supernates
    209. Relation of improvement in endothelium-dependent flow-mediated vasodilation after rosiglitazone to changes in asymmetric dimethylarginine, endothelin-1, and C-reactive protein in nondiabetic patients with the metabolic syndrome.
      Authors: Wang TD, Chen WJ, Cheng WC, Lin JW, Chen MF, Lee YT
      Am. J. Cardiol., 2006;98(8):1057-62.
      Species: Human
      Sample Type: Plasma
    210. Dental plaque, gingival inflammation, and elevated levels of interleukin-6 and cortisol in gingival crevicular fluid from women with stress-related depression and exhaustion.
      Authors: Johannsen A, Rylander G, Soder B, Asberg M
      J. Periodontol., 2006;77(8):1403-9.
      Species: Human
      Sample Type: Gingival Crevicular Fluid (GCF)
    211. The new IL-1 family member IL-1F8 stimulates production of inflammatory mediators by synovial fibroblasts and articular chondrocytes.
      Authors: Magne D, Palmer G, Barton JL, Mezin F, Talabot-Ayer D, Bas S, Duffy T, Noger M, Guerne PA, Nicklin MJ, Gabay C
      Arthritis Res. Ther., 2006;8(3):R80.
      Species: Human
      Sample Type: Cell Culture Supernates
    212. Inhibitory effects of micronized fenofibrate on carotid atherosclerosis in patients with essential hypertension.
      Authors: Zhu S, Su G, Meng QH
      Clin. Chem., 2006;52(11):2036-42.
      Species: Human
      Sample Type: Serum
    213. Transmission of Mycobacterium tuberculosis undetected by tuberculin skin testing.
      Authors: Anderson ST, Williams AJ, Brown JR, Newton SM, Simsova M, Nicol MP, Sebo P, Levin M, Wilkinson RJ, Wilkinson KA
      Am. J. Respir. Crit. Care Med., 2006;173(9):1038-42.
      Species: Human
      Sample Type: Cell Culture Supernates
    214. Induction of dendritic cell maturation by pertussis toxin and its B subunit differentially initiate Toll-like receptor 4-dependent signal transduction pathways.
      Authors: Wang ZY, Yang D, Chen Q, Leifer CA, Segal DM, Su SB, Caspi RR, Howard ZO, Oppenheim JJ
      Exp. Hematol., 2006;34(8):1115-24.
      Species: Human
      Sample Type: Cell Culture Supernates
    215. Functional characterization of a soluble gp130 isoform and its therapeutic capacity in an experimental model of inflammatory arthritis.
      Authors: Richards PJ, Nowell MA, Horiuchi S, McLoughlin RM, Fielding CA, Grau S, Yamamoto N, Ehrmann M, Rose-John S, Williams AS, Topley N, Jones SA
      Arthritis Rheum., 2006;54(5):1662-72.
      Species: Human
      Sample Type: Serum
    216. Urine cytokines profile in renal transplant patients with asymptomatic bacteriuria.
      Authors: Ciszek M, Paczek L, Bartlomiejczyk I, Mucha K
      Transplantation, 2006;81(12):1653-7.
      Species: Human
      Sample Type: Urine
    217. Self-complementary adeno-associated virus vectors containing a novel liver-specific human factor IX expression cassette enable highly efficient transduction of murine and nonhuman primate liver.
      Authors: Nathwani AC, Gray JT, Ng CY, Zhou J, Spence Y, Waddington SN, Tuddenham EG, Kemball-Cook G, McIntosh J, Boon-Spijker M, Mertens K, Davidoff AM
      Blood, 2006;107(7):2653-61.
      Species: Primate - Macaca mulatta (Rhesus Macaque)
      Sample Type: Serum
    218. C-reactive protein induces matrix metalloproteinase-1 and -10 in human endothelial cells: implications for clinical and subclinical atherosclerosis.
      Authors: Montero I, Orbe J, Varo N, Beloqui O, Monreal JI, Rodriguez JA, Diez J, Libby P, Paramo JA
      J. Am. Coll. Cardiol., 2006;47(7):1369-78.
      Species: Human
      Sample Type: Cell Culture Supernates
    219. Respiratory syncytial virus, airway inflammation, and FEV1 decline in patients with chronic obstructive pulmonary disease.
      Authors: Wilkinson TM, Donaldson GC, Johnston SL, Openshaw PJ, Wedzicha JA
      Am. J. Respir. Crit. Care Med., 2006;173(8):871-6.
      Species: Human
      Sample Type: Sputum
    220. Follistatin-like protein-1 is a novel proinflammatory molecule.
      Authors: Miyamae T, Marinov AD, Sowders D, Wilson DC, Devlin J, Boudreau R, Robbins P, Hirsch R
      J. Immunol., 2006;177(7):4758-62.
      Species: Human
      Sample Type: Cell Culture Supernates
    221. Proinflammatory cytokines, insulin resistance, and insulin secretion in chronic hepatitis C patients: A case-control study.
      Authors: Lecube A, Hernandez C, Genesca J, Simo R
      Diabetes Care, 2006;29(5):1096-101.
      Species: Human
      Sample Type: Serum
    222. Influence of eotaxin 67G>A polymorphism on plasma eotaxin concentrations in myocardial infarction survivors and healthy controls.
      Authors: Sheikine Y, Olsen B, Gharizadeh B, Jatta K, Tornvall P, Ghaderi M
      Atherosclerosis, 2006;189(2):458-63.
      Species: Human
      Sample Type: Serum
    223. Serum and urine levels of interleukin-6 and interleukin-8 in children with acute pyelonephritis.
      Authors: Sheu JN, Chen MC, Lue KH, Cheng SL, Lee IC, Chen SM, Tsay GJ
      Cytokine, 2006;36(5):276-82.
      Species: Human
      Sample Type: Serum
    224. Decreased plasma CXCL16/SR-PSOX concentration is associated with coronary artery disease.
      Authors: Sheikine Y, Bang CS, Nilsson L, Samnegard A, Hamsten A, Jonasson L, Eriksson P, Sirsjo A
      Atherosclerosis, 2006;188(2):462-6.
      Species: Human
      Sample Type: Serum
    225. Effect of interactions between lower airway bacterial and rhinoviral infection in exacerbations of COPD.
      Authors: Wilkinson TM, Hurst JR, Perera WR, Wilks M, Donaldson GC, Wedzicha JA
      Chest, 2006;129(2):317-24.
      Species: Human
      Sample Type: Saliva
    226. Function of interleukin-20 as a proinflammatory molecule in rheumatoid and experimental arthritis.
      Authors: Hsu YH, Li HH, Hsieh MY, Liu MF, Huang KY, Chin LS, Chen PC, Cheng HH, Chang MS
      Arthritis Rheum., 2006;54(9):2722-33.
      Species: Human
      Sample Type: Cell Culture Supernates
    227. Non-esterified fatty acid concentrations are independently associated with hepatic steatosis in obese subjects.
      Authors: Holt HB, Wild SH, Wood PJ, Zhang J, Darekar AA, Dewbury K, Poole RB, Holt RI, Phillips DI, Byrne CD
      Diabetologia, 2006;49(1):141-8.
      Species: Human
      Sample Type: Serum
    228. C-reactive protein and vascular cell adhesion molecule-1 as markers of severity in sickle cell disease.
      Authors: Makis AC, Hatzimichael EC, Stebbing J, Bourantas KL
      Arch. Intern. Med., 2006;166(3):366-8.
      Species: Human
      Sample Type: Plasma
    229. Microvascular endothelial cells increase proliferation and inhibit apoptosis of native human acute myelogenous leukemia blasts.
      Authors: Hatfield K, Ryningen A, Corbascio M, Bruserud O
      Int. J. Cancer, 2006;119(10):2313-21.
      Species: Human
      Sample Type: Cell Culture Supernates
    230. Modulation of cytokine secretion by pentacyclic triterpenes from olive pomace oil in human mononuclear cells.
      Authors: Marquez-Martin A, De La Puerta R, Fernandez-Arche A, Ruiz-Gutierrez V, Yaqoob P
      Cytokine, 2006;36(5):211-7.
      Species: Human
      Sample Type: Cell Culture Supernates
    231. Nasal inflammation and personal exposure to fine particles PM2.5 in asthmatic children.
      Authors: Nikasinovic L, Just J, Sahraoui F, Seta N, Grimfeld A, Momas I
      J. Allergy Clin. Immunol., 2006;117(6):1382-8.
      Species: Human
      Sample Type: Nasal Lavage
    232. Celecoxib up-regulates the expression of the zeta chain of T cell receptor complex in tumor-infiltrating lymphocytes in human cervical cancer.
      Authors: Ferrandina G, Ranelletti FO, Legge F, Salutari V, Martinelli E, Fattorossi A, Lorusso D, Zannoni G, Vellone V, Paglia A, Scambia G
      Clin. Cancer Res., 2006;12(7):2055-60.
      Species: Human
      Sample Type: Serum
    233. Kinin receptor expression during Staphylococcus aureus infection.
      Authors: Bengtson SH, Phagoo SB, Norrby-Teglund A, Pahlman L, Morgelin M, Zuraw BL, Leeb-Lundberg LM, Herwald H
      Blood, 2006;108(6):2055-63.
      Species: Human
      Sample Type: Cell Culture Supernates
    234. The apoptotic-cell receptor CR3, but not alphavbeta5, is a regulator of human dendritic-cell immunostimulatory function.
      Authors: Skoberne M, Somersan S, Almodovar W, Truong T, Petrova K, Henson PM, Bhardwaj N
      Blood, 2006;108(3):947-55.
      Species: Human
      Sample Type: Cell Culture Supernates
    235. The potential of adiponectin in driving arthritis.
      Authors: Ehling A, Schaffler A, Herfarth H, Tarner IH, Anders S, Distler O, Paul G, Distler J, Gay S, Scholmerich J, Neumann E, Muller-Ladner U
      J. Immunol., 2006;176(7):4468-78.
      Species: Human
      Sample Type: Cell Culture Supernates
    236. Application of autologous hematopoietic cell therapy to a nonhuman primate model of heterogeneous high-dose irradiation.
      Authors: Bertho JM, Prat M, Frick J, Demarquay C, Gaugler MH, Dudoignon N, Clairand I, Chapel A, Gorin NC, Thierry D, Gourmelon P
      Radiat. Res., 2005;163(5):557-70.
      Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
      Sample Type: Plasma
    237. Increased expression of p38 MAPK in human bronchial epithelium after lipopolysaccharide exposure.
      Authors: Roos-Engstrand E, Wallin A, Bucht A, Pourazar J, Sandstrom T, Blomberg A
      Eur. Respir. J., 2005;25(5):797-803.
    238. Differential responses of serum and salivary interleukin-6 to acute strenuous exercise.
      Authors: Minetto M, Rainoldi A, Gazzoni M, Terzolo M, Borrione P, Termine A, Saba L, Dovio A, Angeli A, Paccotti P
      Eur. J. Appl. Physiol., 2005;93(5):679-86.
      Species: Human
      Sample Type: Serum
    239. Circulating and synovial levels of IGF-I, cytokines, physical function and anthropometry differ in women awaiting total knee arthroplasty when compared to men.
      Authors: Pagura SM, Thomas SG, Woodhouse LJ, Ezzat S, Marks P
      J. Orthop. Res., 2005;23(2):397-405.
      Species: Human
      Sample Type: Synovial Fluid
    240. Up-regulation of macrophage migration inhibitory factor in infants with acute neonatal necrotizing enterocolitis.
      Authors: Ren Y, Lin CL, Li Z, Chen XY, Huang X, Lui V, Nicholls J, Lan HY, Tam PK
      Histopathology, 2005;46(6):659-67.
      Species: Human
      Sample Type: Serum
    241. The role of endothelial cell reactive antibodies in peripheral arterial disease.
      Authors: Armitage JD, Lindsey NJ, Homer-Vanniasinkam S
      Eur J Vasc Endovasc Surg, 2005;31(2):170-5.
      Species: Human
      Sample Type: Serum
    242. Effects of the active metabolite of leflunomide, A77 1726, on cytokine release and the MAPK signalling pathway in human rheumatoid arthritis synoviocytes.
      Authors: Vergne-Salle&lt;/LastName&gt;&lt;F P&lt;/Initial, Vergne-Salle P, Leger DY, Bertin P, Treves R, Beneytout JL, Liagre B
      Cytokine, 2005;31(5):335-48.
      Species: Human
      Sample Type: Cell Culture Supernates
    243. Adiponectin and other adipocytokines as predictors of markers of triglyceride-rich lipoprotein metabolism.
      Authors: Chan DC, Watts GF, Ng TW, Uchida Y, Sakai N, Yamashita S, Barrett PH
      Clin. Chem., 2005;51(3):578-85.
      Species: Human
      Sample Type: Plasma
    244. Aseptic peritonitis due to peptidoglycan contamination of pharmacopoeia standard dialysis solution.
      Authors: Martis L, Patel M, Giertych J, Mongoven J, Taminne M, Perrier MA, Mendoza O, Goud N, Costigan A, Denjoy N, Verger C, Owen WF
      Lancet, 2005;365(9459):588-94.
      Species: Human
      Sample Type: Complex Sample Type
    245. Relationship between cytokines and the embryotoxicity of hydrosalpingeal fluid.
      Authors: Bedaiwy MA, Falcone T, Goldberg JM, Attaran M, Sharma R, Miller K, Nelson DR, Agarwal A
      J. Assist. Reprod. Genet., 2005;22(4):161-5.
      Species: Human
      Sample Type: Hypersalpingeal Fluid (HSF)
    246. Interleukin-6 and interleukin-8 in cervical and amniotic fluid: relationship to microbial invasion of the chorioamniotic membranes.
      Authors: Jacobsson B, Mattsby-Baltzer I, Hagberg H
      BJOG, 2005;112(6):719-24.
      Species: Human
      Sample Type: Cervical Fluid
    247. CD8+ cell depletion amplifies the acute retroviral syndrome.
      Authors: Madden LJ, Zandonatti MA, Flynn CT, Taffe MA, Marcondes MC, Schmitz JE, Reimann KA, Henriksen SJ, Fox HS
      J. Neurovirol., 2004;10(0):58-66.
      Species: Primate - Macaca mulatta (Rhesus Macaque)
      Sample Type: CSF
    248. Pro- and anti-inflammatory responses in respiratory syncytial virus bronchiolitis.
      Authors: McNamara PS, Flanagan BF, Selby AM, Hart CA, Smyth RL
      Eur. Respir. J., 2004;23(1):106-12.
      Species: Human
      Sample Type: BALF
    249. Inflammatory cytokine concentrations are elevated in seminal plasma of men with spinal cord injuries.
      Authors: Basu S, Aballa TC, Ferrell SM, Lynne CM, Brackett NL
      J. Androl., 2004;25(2):250-4.
      Species: Human
      Sample Type: Seminal Plasma
    250. Changes in CSF S100B and cytokine concentrations in early-phase severe traumatic brain injury.
      Authors: Hayakata T, Shiozaki T, Tasaki O, Ikegawa H, Inoue Y, Toshiyuki F, Hosotubo H, Kieko F, Yamashita T, Tanaka H, Shimazu T, Sugimoto H
      Shock, 2004;22(2):102-7.
      Species: Human
      Sample Type: Serum
    251. Presence of dendritic cells, MCP-1, and activated microglia/macrophages in amyotrophic lateral sclerosis spinal cord tissue.
      Authors: Henkel JS, Engelhardt JI, Siklos L, Simpson EP, Kim SH, Pan T, Goodman JC, Siddique T, Beers DR, Appel SH
      Ann. Neurol., 2004;55(2):221-35.
      Species: Human
      Sample Type: CSF
    252. The ideal lavage volume for removing bradykinin, interleukin-6, and protein from the temporomandibular joint by arthrocentesis.
      Authors: Kaneyama K, Segami N, Nishimura M, Sato J, Fujimura K, Yoshimura H
      J. Oral Maxillofac. Surg., 2004;62(6):657-61.
      Species: Human
      Sample Type: Synovial Fluid
    253. Role of transforming growth factor-beta in breast milk for initiation of IgA production in newborn infants.
      Authors: Ogawa J, Sasahara A, Yoshida T, Sira MM, Futatani T, Kanegane H, Miyawaki T
      Early Hum. Dev., 2004;77(1):67-75.
      Species: Human
      Sample Type: Colostrum
    254. Cerebrospinal fluid markers that predict SIV CNS disease.
      Authors: Mankowski JL, Queen SE, Clements JE, Zink MC
      J. Neuroimmunol., 2004;157(1):66-70.
      Species: Primate - Macaca mulatta (Rhesus Macaque)
      Sample Type:
    255. Bronchiectasis, exacerbation indices, and inflammation in chronic obstructive pulmonary disease.
      Authors: Patel IS, Vlahos I, Wilkinson TM, Lloyd-Owen SJ, Donaldson GC, Wilks M, Reznek RH, Wedzicha JA
      Am. J. Respir. Crit. Care Med., 2004;170(4):400-7.
      Species: Human
      Sample Type: Sputum
    256. Hepatocyte growth factor in polymorphonuclear leukocytes is increased in patients with systemic inflammatory response syndrome.
      Authors: Matsushima A, Ogura H, Koh T, Fujita K, Yoshiya K, Sumi Y, Hosotsubo H, Kuwagata Y, Tanaka H, Shimazu T, Sugimoto H
      J Trauma, 2004;56(2):259-64.
      Species: Human
      Sample Type: Plasma
    257. Effect of ozone exposure on airway responses to inhaled allergen in asthmatic subjects.
      Authors: Chen LL, Tager IB, Peden DB, Christian DL, Ferrando RE, Welch BS, Balmes JR
      Chest, 2004;125(6):2328-35.
      Species: Human
      Sample Type: BALF
    258. Human plasmacytoid dendritic cells activated by CpG oligodeoxynucleotides induce the generation of CD4+CD25+ regulatory T cells.
      Authors: Moseman EA, Liang X, Dawson AJ, Panoskaltsis-Mortari A, Krieg AM, Liu YJ, Blazar BR, Chen W
      J. Immunol., 2004;173(7):4433-42.
      Species: Human
      Sample Type: Cell Culture Supernates
    259. High concentrations of circulating macrophage migration inhibitory factor in patients with severe blunt trauma: Is serum macrophage migration inhibitory factor concentration a valuable prognostic factor?
      Authors: Chuang CC, Hung CJ, Tsai MC, Chuang YC
      Crit. Care Med., 2004;32(3):734-9.
      Species: Human
      Sample Type: Serum
    260. Production of interleukin-13 by human dendritic cells after stimulation with protein allergens is a key factor for induction of T helper 2 cytokines and is associated with activation of signal transducer and activator of transcription-6.
      Authors: Bellinghausen I, Brand P, Bottcher I, Klostermann B, Knop J, Saloga J
      Immunology, 2003;108(2):167-76.
      Species: Human
      Sample Type: Cell Culture Supernates
    261. Antidiabetic PPAR gamma-activator rosiglitazone reduces MMP-9 serum levels in type 2 diabetic patients with coronary artery disease.
      Authors: Marx N, Froehlich J, Siam L, Ittner J, Wierse G, Schmidt A, Scharnagl H, Hombach V, Koenig W
      Arterioscler. Thromb. Vasc. Biol., 2003;23(2):283-8.
      Species: Human
      Sample Type: Serum
    262. Multiple brain abscesses in an extremely preterm infant: treatment surveillance with interleukin-6 in the CSF.
      Authors: Heep A, Schaller C, Rittmann N, Himbert U, Marklein G, Bartmann P
      Eur. J. Pediatr., 2003;163(1):44-5.
      Species: Human
      Sample Type: Serum
    263. Association of interleukin-6 and estradiol with hepatocyte growth factor in peritoneal fluid of women with endometriosis.
      Authors: Khan KN, Masuzaki H, Fujishita A, Hamasaki T, Kitajima M, Hasuo A, Miyamura Y, Ishimaru T
      Acta Obstet Gynecol Scand, 2002;81(8):764-71.
      Species: Human
      Sample Type: Peritoneal Fluid
    264. Embryotoxicity of peritoneal fluid in women with endometriosis. Its relation with cytokines and lymphocyte populations.
      Authors: Gomez-Torres MJ, Acien P, Campos A, Velasco I
      Hum. Reprod., 2002;17(3):777-81.
      Species: Human
      Sample Type: Peritoneal Fluid
    265. Macrophage-stimulating protein is produced by tubular cells and activates mesangial cells.
      Authors: Rampino T, Collesi C, Gregorini M
      J. Am. Soc. Nephrol., 2002;13(3):649-57.
      Species: Human
      Sample Type: Cell Culture Supernates
    266. Effect of azacytidine in the release of leukemia inhibitory factor, oncostatin m, interleukin (IL)-6, and IL-11 by mononuclear cells of patients with refractory anemia.
      Authors: Lopez-Karpovitch X, Barrales-Benitez O, Flores M, Piedras J
      Cytokine, 2002;20(4):154-62.
      Species: Human
      Sample Type: Cell Culture Supernates
    267. Endogenously expressed nef uncouples cytokine and chemokine production from membrane phenotypic maturation in dendritic cells.
      Authors: Messmer D, Jacque JM, Santisteban C, Bristow C, Han SY, Villamide-Herrera L, Mehlhop E, Marx PA, Steinman RM, Gettie A, Pope M
      J. Immunol., 2002;169(8):4172-82.
      Species: Human
      Sample Type: Cell Culture Supernates
    268. Intraperitoneal bispecific antibody (HEA125xOKT3) therapy inhibits malignant ascites production in advanced ovarian carcinoma.
      Authors: Marme A, Strauss G, Bastert G, Grischke EM, Moldenhauer G
      Int. J. Cancer, 2002;101(2):183-9.
      Species: Human
      Sample Type: Ascites Fluid
    269. A comparison of multiple urine markers for interstitial cystitis.
      Authors: Erickson DR, Xie SX, Bhavanandan VP, Wheeler MA, Hurst RE, Demers LM, Kushner L, Keay SK
      J. Urol., 2002;167(6):2461-9.
      Species: Human
      Sample Type: Urine
    270. Effects of IL-6 variants in multiple myeloma: growth inhibition and induction of apoptosis in primary cells.
      Authors: Petrucci MT, Ricciardi MR, Gregorj C, Ciapponi L, Savino R, Ciliberto G, Tafuri A
      Leuk. Lymphoma, 2002;43(12):2369-75.
      Species: Human
      Sample Type: Serum
    271. NF-kappaB activation in cerebrospinal fluid cells from patients with meningitis.
      Authors: Ichiyama T, Isumi H, Yoshitomi T, Nishikawa M, Matsubara T, Furukawa S
      Neurol. Res., 2002;24(7):709-12.
      Species: Human
      Sample Type: CSF
    272. Human T-cell leukemia virus type 2 induces survival and proliferation of CD34(+) TF-1 cells through activation of STAT1 and STAT5 by secretion of interferon-gamma and granulocyte macrophage-colony-stimulating factor.
      Authors: Bovolenta C, Pilotti E, Mauri M, Turci M, Ciancianaini P, Fisicaro P, Bertazzoni U, Poli G, Casoli C
      Blood, 2002;99(1):224-31.
      Species: Human
      Sample Type: Cell Culture Supernates
    273. Role of mitogen-activated protein kinase family in serum-induced leukaemia inhibitory factor and interleukin-6 secretion by bone marrow stromal cells.
      Authors: Nakao T, Kim S, Ohta K, Kawano H, Hino M, Miura K, Tatsumi N, Iwao H
      Br. J. Pharmacol., 2002;136(7):975-84.
      Species: Human
      Sample Type: Cell Culture Supernates
    274. An analysis of acute changes in interleukin-6 levels after treatment of hepatitis C with consensus interferon.
      Authors: Cotler SJ, Reddy KR, McCone J, Wolfe DL, Liu A, Craft TR, Ferris MW, Conrad AJ, Albrecht J, Morrissey M, Ganger DR, Rosenblate H, Blatt LM, Jensen DM, Taylor MW
      J. Interferon Cytokine Res., 2001;21(12):1011-9.
      Species: Human
      Sample Type: Serum
    275. Cyclic mechanical stretching modulates secretion pattern of growth factors in human tendon fibroblasts.
      Authors: Skutek M, van Griensven M, Zeichen J, Brauer N, Bosch U
      Eur. J. Appl. Physiol., 2001;86(1):48-52.
      Species: Human
      Sample Type: Cell Culture Supernates
    276. Interleukin-6 is a major effector molecule of short-term G-CSF treatment inducing bone metabolism and an acute-phase response.
      Authors: Carstanjen D, Regenfus M, Muller C, Salama A
      Exp. Hematol., 2001;29(7):812-21.
      Species: Human
      Sample Type: Cell Culture Supernates
    277. High versus low basal cortisol secretion in asymptomatic, medication-free HIV-infected men: differential effects of severe life stress on parameters of immune status.
      Authors: Petitto JM, Leserman J, Perkins DO, Stern RA, Silva SG, Gettes D, Zheng B, Folds JD, Golden RN, Evans DL
      Behav Med, 2000;25(4):143-51.
      Species: Human
      Sample Type: Cell Culture Supernates
    278. Functional genomic analysis in arthritis-affected cartilage: yin-yang regulation of inflammatory mediators by alpha 5 beta 1 and alpha V beta 3 integrins.
      Authors: Attur MG, Dave MN, Clancy RM, Patel IR, Abramson SB, Amin AR
      J. Immunol., 2000;164(5):2684-91.
      Species: Human
      Sample Type: Cell Culture Supernates
    279. Effects of UVB radiation on cytokine generation, cell adhesion molecules, and cell activation markers in T-lymphocytes and peripheral blood HPCs.
      Authors: Lankford KV, Mosunjac M, Hillyer CD
      Transfusion, 2000;40(3):361-7.
      Species: Human
      Sample Type: Cell Culture Supernates
    280. Ovariectomy does not induce osteopenia through interleukin-6 in rhesus monkeys (Macaca mulatta).
      Authors: Keller ET, 49536, Binkley NC, Stebler BA, Hall DM, Johnston GM, Zhang J, Ershler WB
      Bone, 2000;26(1):55-62.
      Species: Primate - Macaca mulatta (Rhesus Macaque)
      Sample Type: Bone Marrow Fluid
    281. Amyloid beta and amylin fibrils induce increases in proinflammatory cytokine and chemokine production by THP-1 cells and murine microglia.
      Authors: Yates SL, Burgess LH, Kocsis-Angle J, Antal JM, Dority MD, Embury PB, Piotrkowski AM, Brunden KR
      J. Neurochem., 2000;74(3):1017-25.
      Species: Human
      Sample Type: Cell Culture Supernates
    282. Proinflammatory cytokines increase in sepsis after anti-adhesion molecule therapy.
      Authors: Welty-Wolf KE, Carraway MS, Ghio A, Kantrow SP, Huang YC, Piantadosi CA
      Shock, 2000;13(5):404-9.
      Species: Primate - Papio cynocephalus (Yellow Baboon)
      Sample Type: Serum
    283. Discriminant power of combined cerebrospinal fluid tau protein and of the soluble interleukin-6 receptor complex in the diagnosis of Alzheimer's disease.
      Authors: Hampel H, Teipel SJ, Padberg F, Haslinger A, Riemenschneider M, Schwarz MJ, Kotter HU, Scheloske M, Buch K, Stubner S, Dukoff R, Lasser R, Moller N, Sunderland T, Rapoport SI, Moller HJ
      Brain Res., 1999;823(1):104-12.
      Species: Human
      Sample Type: CSF
    284. Interleukin-6 and the soluble IL-6 receptor are decreased in cerebrospinal fluid of geriatric patients with major depression: no alteration of soluble gp130.
      Authors: Stubner S, Schon T, Padberg F, Teipel SJ, Schwarz MJ, Haslinger A, Buch K, Dukoff R, Lasser R, Moller N, Sunderland T, Rapoport SI, Moller HJ, Hampel H
      Neurosci. Lett., 1999;259(3):145-8.
    285. High EMT Signature Score of Invasive Non-Small Cell Lung Cancer (NSCLC) Cells Correlates with NFkappaB Driven Colony-Stimulating Factor 2 (CSF2/GM-CSF) Secretion by Neighboring Stromal Fibroblasts.
      Authors: Rudisch A, Dewhurst M, Horga L, Kramer N, Harrer N, Dong M, van der Kuip H, Wernitznig A, Bernthaler A, Dolznig H, Sommergruber W
      PLoS ONE, 0;10(4):e0124283.
      Species: Human
      Sample Type: Cell Culture Supernates
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     Human IL-6 Quantikine ELISA Kit D6050
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      Anonymous 12/04/2017
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     Human IL-6 Quantikine ELISA Kit D6050
    : Human IL-6 Quantikine ELISA Kit [D6050]

    Summary

    Sample Testedprimary human lung small airway epithelial cells

    Other Experimental Details

    Other Experimental DetailsThis result has been published in 10.1371/journal.pone.0058258
     Human IL-6 Quantikine ELISA Kit D6050
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      Anonymous 07/24/2017
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     Human IL-6 Quantikine ELISA Kit D6050
    : Human IL-6 Quantikine ELISA Kit [D6050]

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    Sample Testedsupernatant from human fibroblasts
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    Sample TestedWhole blood neutrophils
     Human IL-6 Quantikine ELISA Kit D6050
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      Anonymous 04/24/2017
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     Human IL-6 Quantikine ELISA Kit D6050
    : Human IL-6 Quantikine ELISA Kit [D6050]

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    Sample TestedSerum

    Other Experimental Details

    Other Experimental DetailsSerum samples used as a dilution of 1/10.
     Human IL-6 Quantikine ELISA Kit D6050
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      Anonymous 04/21/2017
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     Human IL-6 Quantikine ELISA Kit D6050
    : Human IL-6 Quantikine ELISA Kit [D6050]

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    Sample TestedHuman skeletal muscle biopsy

    Other Experimental Details

    Other Experimental DetailsDiluted all samples 1:2 in Calibrator diluent RD6F. Followed instructions for plasma/serum samples.
     Human IL-6 Quantikine ELISA Kit D6050
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      Anonymous 04/21/2017
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     Human IL-6 Quantikine ELISA Kit D6050
    : Human IL-6 Quantikine ELISA Kit [D6050]

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    Sample TestedSerum

    Other Experimental Details

    Other Experimental DetailsProduct D6050 is used daily for Diagnostic use.
     Human IL-6 Quantikine ELISA Kit D6050
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      Anonymous 03/30/2017
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     Human IL-6 Quantikine ELISA Kit D6050
    : Human IL-6 Quantikine ELISA Kit [D6050]

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    Sample TestedHuman Skin Fibroblasts

    Other Experimental Details

    Other Experimental Details0.5x10^6 human primary skin fibroblasts were either left resting or stimulated with the combination of TNF (1ng/mL) and IL-17 (1ng/mL) for 24h. Supernatant volume = 500uL. Two healthy donors. Harvested supernatant was stored at -80°C and used following week in duplicates at a 1/6 dilution. Protocol easy to follow and very reliable (standard always R2=0.99).
     Human IL-6 Quantikine ELISA Kit D6050
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      Anonymous 11/07/2016
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     Human IL-6 Quantikine ELISA Kit D6050
    : Human IL-6 Quantikine ELISA Kit [D6050]

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    Sample Testeduman serum
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      Anonymous 09/30/2016
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    Sample TestedSerum and Plasma

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    Other Experimental DetailsExcellent kit

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