Human L‑Selectin/CD62L Antibody

  • Specificity
    Binds to CHO cells expressing the human L‑Selectin/CD62L protein. It does not recognize CHO cells expressing either the human E-Selectin or human P-Selectin.
  • Source
    Monoclonal Mouse IgG1 Clone # 4G8
  • Purification
    Protein A or G purified from hybridoma culture supernatant
  • Immunogen
    Recombinant human L‑Selectin/CD62L
    Extracellular domain
  • Formulation
    Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
  • Label
  • Flow Cytometry
    2.5 µg/106 cells
    Human whole blood lymphocytes
    • Human L-Selectin/CD62L Sandwich Immunoassay
  • ELISA Capture
    2-8 µg/mL 
    Human L‑Selectin/CD62L Antibody (Catalog # BBA24)
  • ELISA Detection
    0.1-0.4 µg/mL 
    Human L-Selectin/CD62L Biotinylated Antibody (Catalog # BAF728)
  • ELISA Standard
    Recombinant Human L-Selectin/CD62L Protein, CF (Catalog # ADP2)
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Preparation and Storage
  • Reconstitution
    Sterile PBS to a final concentration of 0.5 mg/mL.
  • Shipping
    The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
  • Stability & Storage
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    • 12 months from date of receipt, -20 to -70 °C as supplied.
    • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
    • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: L-Selectin/CD62L
L-Selectin (LAM-1, LECAM-1, LECCAM-1, TQ1, Leu-8, MEL-14 antigen, DREG, lymph node homing receptor, CD62L), is a cell surface glycoprotein expressed constitutively on a wide variety of leukocytes. It plays a role in the migration of lymphocytes into peripheral lymph nodes and sites of chronic inflammation, and of neutrophils into acute inflammatory sites.
  • Entrez Gene IDs:
    6402(Human); 20343(Mouse); 29259(Rat)
  • Alternate Names:
    CD62L; hLHRc; LAM1; LECAM1; Leu-8; LNHR; LSEL; LYAM1; Lyam-1; PLNHR; SELL; TQ1; CD62L; CD62L antigen; gp90-MEL; hLHRc; LAM-1; LAM1LECAM1; LEU8; Leu-8; Leukocyte adhesion molecule 1; Leukocyte surface antigen Leu-8; Leukocyte-endothelial cell adhesion molecule 1; LNHRTQ1; LSEL; L-selectin; Lyam-1; LYAM1CD62 antigen-like family member L; Lymph node homing receptor; lymphocyte adhesion molecule 1; pln homing receptor; PLNHR; selectin L
Related Research Areas

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

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Sample Type
  1. The soluble form of IL-1 receptor accessory protein enhances the ability of soluble type II IL-1 receptor to inhibit IL-1 action.
    Authors: Smith DE, Hanna R, Della Friend, Moore H, Chen H, Farese AM, MacVittie TJ, Virca GD, Sims JE
    Immunity, 2003;18(1):87-96.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow Cytometry,
  2. Attenuated, oncolytic, but not wild-type measles virus infection has pleiotropic effects on human neutrophil function.
    Authors: Zhang Y, Patel B, Dey A, Ghorani E, Rai L, Elham M, Castleton AZ, Fielding AK
    J. Immunol., 2012;188(3):1002-10.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow Cytometry,
  3. Aberration of CCR7 CD8 memory T cells from patients with systemic lupus erythematosus: an inducer of T helper type 2 bias of CD4 T cells.
    Authors: Sen Y, Chunsong H, Baojun H, Linjie Z, Qun L, San J, Qiuping Z, Junyan L, Zhang X, Jinquan T
    Immunology, 2004;112(2):274-89.
    Species: Human
    Sample Type:
    Application: Flow Cytometry,


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