Human Leptin Quantikine ELISA Kit

Catalog # Availability Size / Price Qty
PDLP00
SLP00
DLP00
Control Products Available

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Human Leptin/OB ELISA Standard Curve
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Product Details
Procedure
Citations (136)
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Reviews (9)

Human Leptin Quantikine ELISA Kit Summary

Assay Type
Solid Phase Sandwich ELISA
Format
96-well strip plate
Assay Length
3.5 hours
Sample Type & Volume Required Per Well
Cell Culture Supernates (100 uL), Serum (10 uL), EDTA Plasma (10 uL), Heparin Plasma (10 uL), Citrate Plasma (10 uL)
Sensitivity
7.8 pg/mL
Assay Range
15.6 - 1,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma)
Specificity
Natural and recombinant human Leptin
Cross-reactivity
< 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
Interference
Interference observed with 1 or more available related molecules.

Product Summary

The Quantikine Human Leptin Immunoassay is a 3.5 hour solid phase ELISA designed to measure soluble human Leptin in cell culture supernates, serum, and plasma. It contains E. coli-expressed recombinant human Leptin and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate recombinant Leptin accurately. Results obtained measuring natural human Leptin showed dose-response curves that were parallel to the standard curves obtained using the recombinant Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural human Leptin.

Precision

Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision

Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma

Intra-Assay Precision Inter-Assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 40 40 40
Mean (pg/mL) 64.5 146 621 65.7 146 581
Standard Deviation 2.14 4.32 20 3.56 6.17 20.6
CV% 3.3 3 3.2 5.4 4.2 3.5

Recovery

The recovery of Leptin spiked to three different levels throughout the range of the assay in various matrices was evaluated.

Sample Type Average % Recovery Range %
Cell Culture Media (n=5) 98 94-102
Citrate Plasma (n=5) 95 87-105
EDTA Plasma (n=5) 99 85-112
Heparin Plasma (n=5) 90 81-100
Serum (n=5) 95 89-109

Linearity

To assess the linearity of the assay, cell culture media samples spiked with high concentrations of Leptin and natural serum/plasma samples were diluted with Calibrator Diluent to produce samples with values within the dynamic range of the assay.
Human Leptin/OB ELISA Linearity

Data Examples

Human Leptin/OB ELISA Standard Curve

Product Datasheets

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Preparation and Storage

Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: Leptin/OB

Leptin is a product of the mouse obese gene. Mice with mutations in the obese gene that block the synthesis of leptin are obese and diabetic, and have reduced activity, metabolism, and body temperature. Rat leptin shares approximately 96% and 82% sequence identity with the mouse and human protein, respectively. The expression of leptin mRNA is restricted to adipose tissue.

Entrez Gene IDs:
3952 (Human); 16846 (Mouse); 25608 (Rat)
Alternate Names:
FLJ94114; LEP; leptin (murine obesity homolog); leptin (obesity homolog, mouse); Leptin; OB; Obese protein; obese, mouse, homolog of; Obesity factor; OBOBS
⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Assay Procedure

Refer to the product for complete assay procedure.

Bring all reagents and samples to room temperature before use. It is recommended that all samples, standards, and controls be assayed in duplicate.
  1.   Prepare all reagents, standard dilutions, and samples as directed in the product insert.
  2.   Remove excess microplate strips from the plate frame, return them to the foil pouch containing the desiccant pack, and reseal.

  3. 100 µL Assay Diluent
  4.   Add 100 µL of Assay Diluent to each well.

  5. 100 µL Standard, Control, or Sample
  6.   Add 100 µL of Standard, control, or sample to each well. Cover with a plate sealer, and incubate at room temperature for 2 hours.
  7.   Aspirate each well and wash, repeating the process 3 times for a total of 4 washes.

  8. 200 µL Conjugate
  9.   Add 200 µL of Conjugate to each well. Cover with a new plate sealer, and incubate at room temperature for 1 hour.
  10.   Aspirate and wash 4 times.

  11. 200 µL Substrate Solution
  12.   Add 200 µL Substrate Solution to each well. Incubate at room temperature for 30 minutes. PROTECT FROM LIGHT.

  13. 50 µL Stop Solution
  14.   Add 50 µL of Stop Solution to each well. Read at 450 nm within 30 minutes. Set wavelength correction to 540 nm or 570 nm.

Citations for Human Leptin Quantikine ELISA Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

136 Citations: Showing 1 - 10
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  1. Influence of NAFLD and bariatric surgery on hepatic and adipose tissue mitochondrial biogenesis and respiration
    Authors: JS Pedersen, MO Rygg, K Chrøis, EG Sustarsic, Z Gerhart-Hi, NJ Wever Albr, RR Serizawa, VB Kristianse, AL Basse, AEB Boilesen, BH Olsen, T Hansen, LL Gluud, S Madsbad, S Larsen, F Bendtsen, F Dela
    Nature Communications, 2022;13(1):2931.
    Species: Human
    Sample Types: Plasma
  2. Changes in adipokine levels and metabolic profiles following bariatric surgery
    Authors: N Šebunova, J Štšepetova, T Kullisaar, K Suija, A Rätsep, I Junkin, H Soeorg, M Lember, T Sillakivi, R Mändar
    BMC endocrine disorders, 2022;22(1):33.
    Species: Human
    Sample Types: Serum
  3. Serum Leptin Levels, Nutritional Status, and the Risk of Healthcare-Associated Infections in Hospitalized Older Adults
    Authors: E Paillaud, J Poisson, C Granier, A Ginguay, A Plonquet, C Conti, A Broussier, A Raynaud-Si, S Bastuji-Ga
    Nutrients, 2022;14(1):.
    Species: Human
    Sample Types: Serum
  4. The beneficial effects of intradialytic parenteral nutrition in hemodialysis patients with protein energy wasting: a prospective randomized controlled trial
    Authors: P Kittiskuln, A Banjongjit, K Metta, K Tiranathan, Y Avihingsan, K Praditporn, K Tungsanga, S Eiam-Ong
    Scientific Reports, 2022;12(1):4529.
    Species: Human
    Sample Types: Plasma
  5. Preventing White Adipocyte Browning during Differentiation In Vitro: The Effect of Differentiation Protocols on Metabolic and Mitochondrial Phenotypes
    Authors: E Herbers, M Patrikoski, A Wagner, R Jokinen, A Hassinen, S Heinonen, S Miettinen, H Peltoniemi, E Pirinen, KH Pietiläine
    Stem Cells International, 2022;2022(0):3308194.
    Species: Human
    Sample Types: Cell Culture Supernates
  6. Roles of plasma leptin and resistin in novel subgroups of type 2 diabetes driven by cluster analysis
    Authors: X Peng, J Huang, H Zou, B Peng, S Xia, K Dong, N Sun, J Tao, Y Yang
    Lipids in Health and Disease, 2022;21(1):7.
    Species: Human
    Sample Types: Plasma
  7. High-throughput drug screening models of mature adipose tissues which replicate the physiology of patients' Body Mass Index (BMI)
    Authors: F Louis, Y Sowa, S Kitano, M Matsusaki
    Bioactive materials, 2022;7(0):227-241.
    Species: Human
    Sample Types: Cell Culture Supernates
  8. Leptin-mediated proinflammatory bone marrow environment in acquired aplastic anemia
    Authors: M Gao, M Ge, J Huo, X Ren, X Li, Y Shao, J Huang, J Zhang, M Wang, N Nie, P Jin, Y Zheng
    Cytokine, 2022;152(0):155829.
    Species: Human
    Sample Types: Cell Culture Supernates
  9. Relationship between Epicardial and Coronary Adipose Tissue and the Expression of Adiponectin, Leptin, and Interleukin 6 in Patients with Coronary Artery Disease
    Authors: OV Gruzdeva, YA Dyleva, EV Belik, MY Sinitsky, AN Stasev, AN Kokov, NK Brel, EO Krivkina, EE Bychkova, RS Tarasov, OL Barbarash
    Journal of personalized medicine, 2022;12(2):.
    Species: Human
    Sample Types: Cell Culture Media
  10. Plasma concentration of Bisphenol A and leptin in patients with meningioma and glioma: A pilot study
    Authors: M Komarowska, R Chrzanowsk, M Tylicka, R Rutkowski, Z Mariak, B Zelazowska, T Lyson, A Hermanowic
    Advances in medical sciences, 2022;67(2):229-233.
    Species: Human
    Sample Types: Plasma
  11. Relationship between metabolic syndrome and follicle-stimulating hormone in postmenopausal women
    Authors: SW Lee, IS Hwang, G Jung, HJ Kang, YH Chung
    Medicine, 2022;101(18):e29216.
    Species: Human
    Sample Types: Serum
  12. Sex differences in the relationship between body composition and biomarkers of bone and fat metabolism in obese boys and girls
    Authors: R Khwanchuea, C Punsawad
    Bone Reports, 2021;14(0):101087.
    Species: Human
    Sample Types: Serum
  13. Level of Adiponectin, Leptin and Selected Matrix Metalloproteinases in Female Overweight Patients with Primary Gonarthrosis
    Authors: J Jarecki, T Ma?ecka-Ma, I Polkowska, B Potoczniak, E Kosior-Jar, I Szerb, E Tomaszewsk, M Gutbier, M Dobrzy?ski, T Blicharski
    Journal of Clinical Medicine, 2021;10(6):.
    Species: Human
    Sample Types: Serum
  14. The Role of Leptin in Childhood Immune Thrombocytopenia (ITP): An Anti-Inflammatory Agent?
    Authors: I Thomas, I Panagoulia, I Aggeletopo, A Varvarigou, BE Spiliotis, A Mouzaki
    International Journal of Molecular Sciences, 2021;22(14):.
    Species: Mouse
    Sample Types: Plasma
  15. Lactobacillus plantarum 299v probiotic supplementation in men with stable coronary artery disease suppresses systemic inflammation
    Authors: BC Hofeld, VK Puppala, S Tyagi, KW Ahn, A Anger, S Jia, NH Salzman, MJ Hessner, ME Widlansky
    Scientific Reports, 2021;11(1):3972.
    Species: Human
    Sample Types: Plasma
  16. Biomarkers of Oncogenesis, Adipose Tissue Dysfunction and Systemic Inflammation for the Detection of Hepatocellular Carcinoma in Patients with Nonalcoholic Fatty Liver Disease
    Authors: GP Caviglia, A Armandi, C Rosso, S Gaia, S Aneli, E Rolle, ML Abate, A Olivero, A Nicolosi, M Guariglia, DG Ribaldone, P Carucci, GM Saracco, E Bugianesi
    Cancers, 2021;13(10):.
    Species: Human
    Sample Types: Plasma
  17. Adiponectin as a novel biomarker of disease severity in alopecia areata
    Authors: A Stochmal, A Wa?kiel-Bu, S Chrostowsk, M Zaremba, A Rakowska, J Czuwara, L Rudnicka
    Scientific Reports, 2021;11(1):13809.
    Species: Human
    Sample Types: Serum
  18. Exploring the Mechanisms of Recovery in Anorexia Nervosa through a Translational Approach: From Original Ecological Measurements in Human to Brain Tissue Analyses in Mice
    Authors: P Duriez, IAK Nilsson, O Le Thuc, D Alexandre, N Chartrel, C Rovere, C Chauveau, P Gorwood, V Tolle, O Viltart
    Nutrients, 2021;13(8):.
    Species: Human
    Sample Types: Plasma
  19. AntiTNF-alpha therapy normalizes levels of lipids and adipokines in psoriatic patients in the real-life settings
    Authors: I Olejniczak, J Narbutt, J Ceryn, M Skibi?ska, I Bednarski, A Wo?niacka, J Sieniawska, M Kraska-Gac, M Ci??y?ska, J ?migielski, M Noweta, M Waszczykow, W Owczarek, A Reich, A Lesiak
    Scientific Reports, 2021;11(1):9289.
    Species: Human
    Sample Types: Serum
  20. Adipocytokines in Untreated Newly Diagnosed Rheumatoid Arthritis: Association with Circulating Chemokines and Markers of Inflammation
    Authors: GK Vasileiadi, AC Lundell, Y Zhang, K Andersson, I Gjertsson, A Rudin, C Maglio
    Biomolecules, 2021;11(2):.
    Species: Human
    Sample Types: Plasma
  21. Epigenetic Regulation of Processes Related to High Level of Fibroblast Growth Factor 21 in Obese Subjects
    Authors: T P?atek, A Polus, J Góralska, U Ra?ny, A Dziewo?ska, A Micek, A Dembi?ska-, B Solnica, M Malczewska
    Genes, 2021;12(2):.
    Species: Human
    Sample Types: Serum
  22. The Contribution of the Hunger Hormone Leptin in the Aetiology of Postoperative Anorexia after Laparoscopic and Open Gastrectomy in Gastric Cancer Patients
    Authors: T Jagric
    Biomolecules, 2021;11(11):.
    Species: Human
    Sample Types: Serum
  23. Association of Maternal Microbiota and Diet in Cord Blood Cytokine and Immunoglobulin Profiles
    Authors: K Rio-Aige, I Azagra-Bor, M Massot-Cla, M Selma-Royo, A Parra-Llor, S González, I García-Man, M Castell, MJ Rodríguez-, MC Collado, FJ Pérez Cano
    International Journal of Molecular Sciences, 2021;22(4):.
    Species: Human
    Sample Types: Plasma
  24. Improvement of Inflammation and Pain after Three Months' Exclusion Diet in Rheumatoid Arthritis Patients
    Authors: MT Guagnano, C D'Angelo, D Caniglia, P Di Giovann, E Celletti, E Sabatini, L Speranza, M Bucci, F Cipollone, R Paganelli
    Nutrients, 2021;13(10):.
    Species: Human
    Sample Types: Serum
  25. Physical activity during pregnancy and association with changes in fat mass and adipokines in women of normal-weight or with obesity
    Authors: U Andersson-, H de Maré, F Askeli, M Börjesson, A Holmäng
    Scientific Reports, 2021;11(1):12549.
    Species: Human
    Sample Types: Serum
  26. Association of serum adiponectin and myostatin levels with skeletal muscle in patients with obesity: A cross-sectional study
    Authors: S Kurose, K Onishi, N Takao, T Miyauchi, K Takahashi, Y Kimura
    PLoS ONE, 2021;16(1):e0245678.
    Species: Human
    Sample Types: Serum
  27. Expression of adipocytokines in heart fat depots depending on the degree of coronary artery atherosclerosis in patients with coronary artery disease
    Authors: OV Gruzdeva, EV Belik, YA Dyleva, DA Borodkina, MY Sinitsky, DY Naumov, EE Bychkova, EV Fanaskova, EI Palicheva, AA Kuzmina, VN Karetnikov, OL Barbarash
    PLoS ONE, 2021;16(3):e0248716.
    Species: Human
    Sample Types: Tissue Homogenates
  28. Associations between prenatal serum levels of leptin, IGF-I, and estradiol and adolescent mothers' height gain during and after pregnancy
    Authors: R Sámano, H Martínez-R, G Chico-Barb, M Hernández-, R Guzmán, G Arteaga-Tr, MA Figueroa-P, RM Morales, G Martínez
    PLoS ONE, 2020;15(2):e0228706.
    Species: Human
    Sample Types: Serum
  29. Influence of Short-Term Hyperenergetic, High-Fat Feeding on Appetite, Appetite-Related Hormones, and Food Reward in Healthy Men
    Authors: AE Thackray, SA Willis, DJ Clayton, DR Broom, G Finlayson, FR Goltz, JA Sargeant, RM Woods, DJ Stensel, JA King
    Nutrients, 2020;12(9):.
    Species: Human
    Sample Types: Plasma
  30. Chronic mirabegron treatment increases human brown fat, HDL cholesterol, and insulin sensitivity
    Authors: AE O'Mara, JW Johnson, JD Linderman, RJ Brychta, S McGehee, LA Fletcher, YA Fink, D Kapuria, TM Cassimatis, N Kelsey, C Cero, Z Abdul-Sate, F Piccinini, AS Baskin, BP Leitner, H Cai, CM Millo, W Dieckmann, M Walter, NB Javitt, Y Rotman, PJ Walter, M Ader, RN Bergman, P Herscovitc, KY Chen, AM Cypess
    J. Clin. Invest., 2020;0(0):.
    Species: Human
    Sample Types: Plasma
  31. Monounsaturated fat rapidly induces hepatic gluconeogenesis and whole-body insulin resistance
    Authors: T Sarabhai, S Kahl, J Szendroedi, DF Markgraf, OP Zaharia, C Barosa, C Herder, F Wickrath, P Bobrov, JH Hwang, JG Jones, M Roden
    JCI Insight, 2020;5(10):.
    Species: Human
    Sample Types: Serum
  32. SIV Infection and the HIV Proteins Tat and Nef Induce Senescence in Adipose Tissue and Human Adipose Stem Cells, Resulting in Adipocyte Dysfunction
    Authors: J Gorwood, T Ejlalmanes, C Bourgeois, M Mantecon, C Rose, M Atlan, D Desjardins, R Le Grand, B Fève, O Lambotte, J Capeau, V Béréziat, C Lagathu
    Cells, 2020;9(4):.
    Species: Human
    Sample Types: Cell Culture Supernates
  33. Circulating leptin levels are associated with adiposity in survivors of childhood brain tumors
    Authors: ED Sims, WJ Jennings, B Empringham, A Fleming, C Portwine, DL Johnston, SM Zelcer, SR Rassekh, S Burrow, L Thabane, MC Samaan
    Sci Rep, 2020;10(1):4711.
    Species: Human
    Sample Types: Plasma
  34. Effects of underfeeding and oral vancomycin on gut microbiome and nutrient absorption in humans
    Authors: A Basolo, M Hohenadel, QY Ang, P Piaggi, S Heinitz, M Walter, P Walter, S Parrington, DD Trinidad, RJ von Schwar, PJ Turnbaugh, J Krakoff
    Nat. Med., 2020;26(4):589-598.
    Species: Human
    Sample Types: Plasma
  35. Influence of Short-Term Hyperenergetic, High-Fat Feeding on Appetite, Appetite-Related Hormones, and Food Reward in Healthy Men
    Authors: AE Thackray, SA Willis, DJ Clayton, DR Broom, G Finlayson, FR Goltz, JA Sargeant, RM Woods, DJ Stensel, JA King
    Nutrients, 2020;12(9):.
    Species: Human
    Sample Types: Plasma
  36. The Link between Obesity and Inflammatory Markers in the Development of Type 2 Diabetes in Men of Black African and White European Ethnicity
    Authors: O Hakim, O Bello, M Ladwa, JL Peacock, AM Umpleby, G Charles-Ed, SA Amiel, LM Goff
    Nutrients, 2020;12(12):.
    Species: Human
    Sample Types: Plasma
  37. APOE-&epsilon4-related differences in left thalamic microstructure in cognitively healthy adults
    Authors: JP Mole, F Fasano, J Evans, R Sims, E Kidd, JP Aggleton, C Metzler-Ba
    Sci Rep, 2020;10(1):19787.
    Species: Human
    Sample Types: Plasma
  38. Statin therapy is associated with lower prevalence of gut microbiota dysbiosis
    Authors: S Vieira-Sil, G Falony, E Belda, T Nielsen, J Aron-Wisne, R Chakaroun, SK Forslund, K Assmann, M Valles-Col, TTD Nguyen, S Proost, E Prifti, V Tremaroli, N Pons, E Le Chateli, F Andreelli, JP Bastard, LP Coelho, N Galleron, TH Hansen, JS Hulot, C Lewinter, HK Pedersen, B Quinquis, C Rouault, H Roume, JE Salem, NB Søndertoft, S Touch,, ME Dumas, SD Ehrlich, P Galan, JP Gøtze, T Hansen, JJ Holst, L Køber, I Letunic, J Nielsen, JM Oppert, M Stumvoll, H Vestergaar, JD Zucker, P Bork, O Pedersen, F Bäckhed, K Clément, J Raes
    Nature, 2020;581(7808):310-315.
    Species: Human
    Sample Types: Serum
  39. Pain in women with knee and/or hip osteoarthritis is related to systemic inflammation and to adipose tissue dysfunction: Cross-sectional results of the KHOALA cohort
    Authors: J Sellam, AC Rat, S Fellahi, JP Bastard, W Ngueyon Si, HK Ea, X Chevalier, P Richette, J Capeau, F Guillemin, F Berenbaum
    Seminars in arthritis and rheumatism, 2020;51(1):129-136.
    Species: Human
    Sample Types: Serum
  40. High- or moderate-intensity training promotes change in cardiorespiratory fitness, but not visceral fat, in obese men: A randomised trial of equal energy expenditure exercise
    Authors: J Gerosa-Net, VLG Panissa, PA Monteiro, DS Inoue, JPJ Ribeiro, C Figueiredo, AM Zagatto, JP Little, FS Lira
    Respir Physiol Neurobiol, 2019;266(0):150-155.
    Species: Human
    Sample Types: Serum
  41. Hormonal, metabolic and inflammatory circulating biomarker profiles in obese and non-obese Brazilian middle-aged women
    Authors: LV Galvão-Mor, ACB Nascimento, IMSC D'Albuquer, MAS Sousa, HO Brito, MDDSB Nascimento, MB da Costa C, LMO Brito
    PLoS ONE, 2019;14(9):e0222239.
    Species: Human
    Sample Types: Serum
  42. Daily walnut intake improves metabolic syndrome status and increases circulating adiponectin levels: randomized controlled crossover trial
    Authors: HJ Hwang, Y Liu, HS Kim, H Lee, Y Lim, H Park
    Nutr Res Pract, 2019;13(2):105-114.
    Species: Human
    Sample Types: Serum
  43. FABP4 in Gestational Diabetes-Association between Mothers and Offspring
    Authors: J Patro-Ma?y, M Trojnar, ? Kimber-Tro, R Mierzy?ski, J Bartosiewi, J Oleszczuk, B Leszczy?sk
    J Clin Med, 2019;8(3):.
    Species: Human
    Sample Types: Serum
  44. The effect of resistance exercise upon age-related systemic and local skeletal muscle inflammation
    Authors: AK Ziegler, SM Jensen, P Schjerling, AL Mackey, JL Andersen, M Kjaer
    Exp. Gerontol., 2019;121(0):19-32.
    Species: Human
    Sample Types: Serum
  45. Sex difference in the mediation roles of an inflammatory factor (hsCRP) and adipokines on the relationship between adiposity and blood pressure
    Authors: YD Yang, CJ Zheng, YH Dong, ZY Zou, Y Lv, ZH Wang, ZG Yang, S Wang, B Dong, J Ma
    Hypertens. Res., 2019;0(0):.
    Species: Human
    Sample Types: Serum
  46. Long Pentraxin 3 as a Broader Biomarker for Multiple Risk Factors in End-Stage Renal Disease: Association with All-Cause Mortality
    Authors: MJ Valente, S Rocha, S Coimbra, C Catarino, P Rocha-Pere, E Bronze-da-, JG Oliveira, J Madureira, JC Fernandes, M do Sameiro, V Miranda, L Belo, A Santos-Sil
    Mediators Inflamm., 2019;2019(0):3295725.
    Species: Human
    Sample Types: Plasma
  47. Multilevel defects in the hematopoietic niche in essential thrombocythemia
    Authors: T Sun, M Ju, X Dai, H Dong, W Gu, Y Gao, R Fu, X Liu, Y Huang, W Liu, Y Chi, W Wang, H Li, Y Zhou, L Shi, R Yang, L Zhang
    Haematologica, 2019;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  48. Association between genetically determined leptin and blood lipids considering alcohol consumption: a Mendelian randomisation study
    Authors: L Shen, JF Cordero, JS Wang, Y Shen, S Li, L Liang, Z Zou, C Li
    BMJ Open, 2019;9(11):e026860.
    Species: Human
    Sample Types: Serum
  49. Biological variation of immunological blood biomarkers in healthy individuals and quality goals for biomarker tests
    Authors: N Aziz, R Detels, JJ Quint, D Gjertson, T Ryner, AW Butch
    BMC Immunol., 2019;20(1):33.
    Species: Human
    Sample Types: Serum
  50. Serum CA125 and ascites leptin level ratio predicts baseline clinical resistance to first-line platinum-based treatment and poor prognosis in patients with high grade serous ovarian cancer
    Authors: I Matte, P Garde-Gran, P Bessette, A Piché
    Am J Cancer Res, 2019;9(1):160-170.
    Species: Human
    Sample Types: Ascites Fluid
  51. Inter-ictal assay of peripheral circulating inflammatory mediators in migraine patients under adjunctive cervical non-invasive vagus nerve stimulation (nVNS): A proof-of-concept study
    Authors: SR Chaudhry, IS Lendvai, S Muhammad, P Westhofen, J Kruppenbac, L Scheef, H Boecker, D Scheele, R Hurlemann, TM Kinfe
    Brain Stimul, 2019;0(0):.
    Species: Human
    Sample Types: Serum
  52. Maternal pre-pregnancy weight status modifies the influence of PUFAs and inflammatory biomarkers in breastmilk on infant growth
    Authors: H Nuss, A Altazan, J Zabaleta, M Sothern, L Redman
    PLoS ONE, 2019;14(5):e0217085.
    Species: Human
    Sample Types: Serum
  53. Breast Milk Supply of MicroRNA Associated with Leptin and Adiponectin Is Affected by Maternal Overweight/Obesity and Influences Infancy BMI
    Authors: R Zamanillo, J Sánchez, F Serra, A Palou
    Nutrients, 2019;11(11):.
    Species: Human
    Sample Types: Milk
  54. Association of serum leptin and adiponectin concentrations with echocardiographic parameters and pathophysiological states in patients with cardiovascular disease receiving cardiovascular surgery
    Authors: T Sawaguchi, T Nakajima, A Haruyama, T Hasegawa, I Shibasaki, T Nakajima, H Kaneda, T Arikawa, S Obi, M Sakuma, H Ogawa, Y Takei, S Toyoda, F Nakamura, S Abe, H Fukuda, T Inoue
    PLoS ONE, 2019;14(11):e0225008.
    Species: Human
    Sample Types: Serum
  55. Developmental trajectories of body mass index from childhood into late adolescence and subsequent late adolescence-young adulthood cardiometabolic risk markers
    Authors: K Oluwagbemi, AE Buyken, U Alexy, M Schmid, C Herder, U Nöthlings
    Cardiovasc Diabetol, 2019;18(1):9.
    Species: Human
    Sample Types: Plasma
  56. Lower levels of leptin are associated with severity parameters in visceral leishmaniasis patients
    Authors: AMDC Fievez, ML Silva-Frei, AQ Sousa, JR Santos-Oli, AM Da-Cruz
    PLoS ONE, 2019;14(3):e0214413.
    Species: Human
    Sample Types: Serum
  57. Differences in biochemical markers between Heart-transplanted and Left Ventricular Assist Device implanted patients, during cardiac rehabilitation
    Authors: V Racca, P Castiglion, C Panzarino, M Saresella, I Marventano, A Verde, F Oliva, M Ferratini
    Sci Rep, 2018;8(1):10816.
    Species: Human
    Sample Types: Serum
  58. Fasting plasma mannose levels are associated with insulin sensitivity independent of BMI in Japanese individuals with diabetes
    Authors: E Amano, S Funakoshi, K Yoshimura, S Hirano, S Ohmi, H Takata, Y Terada, S Fujimoto
    Diabetol Metab Syndr, 2018;10(0):88.
    Species: Human
    Sample Types: Serum
  59. The impact of human breast milk components on the infant metabolism
    Authors: C Hellmuth, O Uhl, H Demmelmair, M Grunewald, R Auricchio, G Castillejo, IR Korponay-S, I Polanco, M Roca, SL Vriezinga, KJ Werkstette, B Koletzko, ML Mearin, FF Kirchberg
    PLoS ONE, 2018;13(6):e0197713.
    Species: Human
    Sample Types: Milk
  60. Association between UCP polymorphisms and adipokines with obesity in Mexican adolescents
    Authors: R Sámano, C Huesca-Góm, R López-Maru, AK Hernández-, A Rodríguez-, M Tolentino, RM Morales, R Gamboa
    J. Pediatr. Endocrinol. Metab., 2018;0(0):.
    Species: Human
    Sample Types: Serum
  61. Interleukin-6 and leptin levels are associated with preoperative pain severity in patients with osteoarthritis but not with acute pain after total knee arthroplasty
    Authors: S Azim, J Nicholson, MJ Rebecchi, W Galbavy, T Feng, S Rizwan, RA Reinsel, M Kaczocha, H Benveniste
    Knee, 2018;0(0):.
    Species: Human
    Sample Types: Serum
  62. C-Reactive protein in relation to fecundability and anovulation among eumenorrheic women
    Authors: RG Radin, LA Sjaarda, RM Silver, CJ Nobles, SL Mumford, NJ Perkins, BD Wilcox, AZ Pollack, KC Schliep, TC Plowden, EF Schisterma
    Fertil. Steril., 2018;0(0):.
    Species: Human
    Sample Types: Serum
  63. Development of Versatile Human In Vitro Vascularized Adipose Tissue Model with Serum-Free Angiogenesis and Natural Adipogenesis Induction
    Authors: O Huttala, M Palmroth, P Hemminki, T Toimela, T Heinonen, T Ylikomi, JR Sarkanen
    Basic Clin. Pharmacol. Toxicol., 2018;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  64. Follicular fluid levels of anti-M�llerian hormone, insulin-like growth factor 1 and leptin in women with fertility disorders
    Authors: R Kucera, V Babuska, Z Ulcova-Gal, V Kulda, O Topolcan
    Syst Biol Reprod Med, 2018;0(0):1-4.
    Species: Human
    Sample Types: Follicular Fluid
  65. Plasma leptin, but not resistin, TNF-? and adiponectin, is associated with echocardiographic parameters of cardiac remodeling in patients with coronary artery disease
    Authors: AD Farca?, A Rusu, MA Stoia, LA Vida-Simit
    Cytokine, 2018;103(0):46-49.
    Species: Human
    Sample Types: Plasma
  66. The circulating metabolome of human starvation
    Authors: ML Steinhause, BA Olenchock, J O'Keefe, M Lun, KA Pierce, H Lee, L Pantano, A Klibanski, GI Shulman, CB Clish, PK Fazeli
    JCI Insight, 2018;3(16):.
    Species: Human
    Sample Types: Plasma
  67. Is There Any Relationship between Plasma 25-Hydroxyvitamin D?, Adipokine Profiles and Excessive Body Weight in Type 2 Diabetic Patients?
    Authors: J Kocot, P Dziemidok, M Kie?czykow, J Kurzepa, G Szcze?niak, I Musik
    Int J Environ Res Public Health, 2017;15(1):.
    Species: Human
    Sample Types: Plasma
  68. Myostatin and adipokines: The role of the metabolically unhealthy obese phenotype in muscle function and aerobic capacity in young adults
    Authors: LP Carvalho, RP Basso-Vane, L Di Thommaz, RG Mendes, MC Oliveira-J, RP Vieira, JC Bonjorno-J, CR Oliveira, R Luporini, A Borghi-Sil
    Cytokine, 2017;0(0):.
    Species: Human
    Sample Types: Plasma
  69. Reproductive hormones and metabolic syndrome in 24 testicular cancer survivors and their biological brothers
    Authors: M Bandak, N Jørgensen, A Juul, J Lauritsen, MGG Kier, MS Mortensen, PS Oturai, J Mortensen, P Hojman, JW Helge, G Daugaard
    Andrology, 2017;0(0):.
    Species: Human
    Sample Types: Serum
  70. Impact of physical activity level and dietary fat content on passive overconsumption of energy in non-obese adults
    Authors: K Beaulieu, M Hopkins, J Blundell, G Finlayson
    Int J Behav Nutr Phys Act, 2017;14(1):14.
    Species: Human
    Sample Types: Plasma
  71. Effects of exercise training on circulating levels of Dickkpof-1 and secreted frizzled-related protein-1 in breast cancer survivors: A pilot single-blind randomized controlled trial
    Authors: TH Kim, JS Chang, KS Park, J Park, N Kim, JI Lee, ID Kong
    PLoS ONE, 2017;12(2):e0171771.
    Species: Human
    Sample Types: Serum
  72. Endurance exercise training decreased serum levels of surfactant protein D and improved aerobic fitness of obese women with type-2 diabetes
    Authors: S Rezaei, MM Shamsi, M Mahdavi, A Jamali, J Prestes, RA Tibana, JW Navalta, FA Voltarelli
    Diabetol Metab Syndr, 2017;9(0):74.
    Species: Human
    Sample Types: Serum
  73. Concurrent Aerobic and Resistance Training Has Anti-Inflammatory Effects and Increases Both Plasma and Leukocyte Levels of IGF-1 in Late Middle-Aged Type 2 Diabetic Patients
    Authors: G Annibalini, F Lucertini, D Agostini, L Vallorani, A Gioacchini, E Barbieri, M Guescini, L Casadei, A Passalia, M Del Sal, G Piccoli, M Andreani, A Federici, V Stocchi
    Oxid Med Cell Longev, 2017;2017(0):3937842.
    Species: Human
    Sample Types: Plasma
  74. Adipokines, C-reactive protein and Amyotrophic Lateral Sclerosis - results from a population- based ALS registry in Germany
    Authors: G Nagel, RS Peter, A Rosenbohm, W Koenig, L Dupuis, D Rothenbach, AC Ludolph
    Sci Rep, 2017;7(1):4374.
    Species: Human
    Sample Types: Serum
  75. Serum levels of leptin and adiponectin and clinical parameters in women with fibromyalgia and overweight/obesity
    Authors: ES Paiva, A Andretta, ED Batista, MM Lobo, RC Miranda, R Nisihara, ME Schieferde, CL Boguszewsk
    Arch Endocrinol Metab, 2017;0(0):0.
    Species: Human
    Sample Types: Serum
  76. Type II Endometrial Cancer Overexpresses NILCO: A Preliminary Evaluation
    Authors: D Daley-Brow, G Oprea-Iles, KT Vann, V Lanier, R Lee, PV Candelaria, A Quarshie, R Pattillo, RR Gonzalez-P
    Dis. Markers, 2017;2017(0):8248175.
    Species: Human
    Sample Types: Tissue Homogenates
  77. The effect of BMI, serum leptin, and adiponectin levels on prognosis in patients with non-ischaemic dilated cardiomyopathy
    Authors: C Wojciechow, W Jache?, E Romuk, E Nowalany-K, A Tomasik, L Siemi?ska
    Endokrynol Pol, 2017;68(1):26-34.
    Species: Human
    Sample Types: Serum
  78. Ghrelin and hormonal markers under exercise training in patients with heart failure with preserved ejection fraction: results from the Ex-DHF pilot study
    Authors: TD Trippel, V Holzendorf, M Halle, G Gelbrich, K Nolte, A Duvinage, S Schwarz, T Rutscher, J Wiora, R Wachter, C Herrmann-L, HD Duengen, G Hasenfu beta, B Pieske, F Edelmann
    ESC Heart Fail, 2017;4(1):56-65.
    Species: Human
    Sample Types: Serum
  79. Plasma irisin is elevated in type 2 diabetes and is associated with increased E-selectin levels
    Authors: KS Rana, C Pararasa, I Afzal, DA Nagel, EJ Hill, CJ Bailey, HR Griffiths, I Kyrou, HS Randeva, S Bellary, JE Brown
    Cardiovasc Diabetol, 2017;16(1):147.
    Species: Human
    Sample Types: Plasma
  80. Class II obese and healthy pregnant controls exhibit indistinguishable pro- and anti-inflammatory immune responses to Caesarian section
    Authors: C Graham, M Thorleifso, WP Stefura, DJ Funk, KT HayGlass
    Immun Inflamm Dis, 2017;0(0):.
    Species: Human
    Sample Types: Plasma
  81. Carbohydrates from Sources with a Higher Glycemic Index during Adolescence: Is Evening Rather than Morning Intake Relevant for Risk Markers of Type 2 Diabetes in Young Adulthood?
    Authors: T Diederichs, C Herder, S Ro beta bach, M Roden, SA Wudy, U Nöthlings, U Alexy, AE Buyken
    Nutrients, 2017;9(6):.
    Species: Human
    Sample Types: Serum
  82. Key Clinical Factors Predicting Adipokine and Oxidative Stress Marker Concentrations among Normal, Overweight and Obese Pregnant Women Using Artificial Neural Networks
    Authors: M Solis-Pare, G Estrada-Gu, O Perichart-, A Montoya-Es, M Guzmán-Hue, H Borboa-Oli, E Bravo-Flor, A Cardona-Pé, V Zaga-Clave, E Garcia-Lat, G Gonzalez-P, JA Hernández-, C Irles
    Int J Mol Sci, 2017;19(1):.
    Species: Human
    Sample Types: Serum
  83. Relationships of insulin-like growth factor-1, its binding proteins, and cardiometabolic risk in hypertensive perimenopausal women
    Authors: A Olszanecka, A Dragan, K Kawecka-Ja, D Fedak, D Czarnecka
    Metab. Clin. Exp., 2017;69(0):96-106.
    Species: Human
    Sample Types: Plasma
  84. Serum levels of adiponectin and leptin as biomarkers of proteinuria in lupus nephritis
    Authors: V Diaz-Rizo, D Bonilla-La, L Gonzalez-L, D Sanchez-Mo, NS Fajardo-Ro, EE Perez-Guer, NA Rodriguez-, AM Saldaña-Cr, ML Vazquez-Vi, E Gomez-Bañu, M Vazquez-De, EG Cardona-Mu, D Cardona-Mu, X Trujillo, M Huerta, M Salazar-Pa, JI Gamez-Nava
    PLoS ONE, 2017;12(9):e0184056.
    Species: Human
    Sample Types: Serum
  85. Inkjet-printed point-of-care immunoassay on a nanoscale polymer brush enables subpicomolar detection of analytes in blood
    Authors: DY Joh, AM Hucknall, Q Wei, KA Mason, ML Lund, CM Fontes, RT Hill, R Blair, Z Zimmers, RK Achar, D Tseng, R Gordan, M Freemark, A Ozcan, A Chilkoti
    Proc. Natl. Acad. Sci. U.S.A., 2017;0(0):.
    Species: Human
    Sample Types: Serum
  86. Altered Systemic Adipokines in Patients with Chronic Urticaria
    Authors: Hoang Kim Tu Trinh
    Int. Arch. Allergy Immunol, 2016;171(2):102-110.
    Species: Human
    Sample Types: Serum
  87. Metabolic Syndrome and Selective Inflammatory Markers in Psoriatic Patients
    Authors: S Vachatova, C Andrys, J Krejsek, M Salavec, K Ettler, V Rehacek, E Cermakova, A Malkova, Z Fiala, L Borska
    J Immunol Res, 2016;2016(0):5380792.
    Species: Human
    Sample Types: Serum
  88. Maternal obesity drives functional alterations in uterine NK cells
    JCI Insight, 2016;1(11):e85560.
    Species: Human
    Sample Types: Serum
  89. Leptin, Leptin Soluble Receptor, and the Free Leptin Index following a Diet and Physical Activity Lifestyle Intervention in Obese Males and Females
    Authors: Jeffrey E Herrick
    J Obes, 2016;2016(0):8375828.
    Species: Human
    Sample Types: Serum
  90. Effects of different degrees of insulin resistance on endothelial function in�obese�adults undergoing alternate day�fasting
    Authors: Kristin K Hoddy
    Nutr Healthy Aging, 2016;4(1):63-71.
    Species: Human
    Sample Types: Plasma
  91. Type 3 Deiodinase Role on Central Thyroid Hormone Action Affects the Leptin-Melanocortin System and Circadian Activity
    Authors: Zhaofei Wu
    Endocrinology, 2016;0(0):en20161680.
    Species: Human
    Sample Types: Serum
  92. Dietary patterns and cardiometabolic and endocrine plasma biomarkers in US women
    Authors: Hala B AlEssa
    Am. J. Clin. Nutr, 2016;0(0):.
    Species: Human
    Sample Types: Plasma
  93. Circulating adipokines and insulin resistance in subjects with combined cardiac and metabolic syndrome X.
    Authors: Liang K, Lee W, Lee W, Liao Y, Wang K, Lee I, Wang J, Sheu W
    Diabetol Metab Syndr, 2015;7(0):83.
    Species: Human
    Sample Types: Serum
  94. A Dietary Supplement Containing Cinnamon, Chromium and Carnosine Decreases Fasting Plasma Glucose and Increases Lean Mass in Overweight or Obese Pre-Diabetic Subjects: A Randomized, Placebo-Controlled Trial.
    Authors: Liu Y, Cotillard A, Vatier C, Bastard J, Fellahi S, Stevant M, Allatif O, Langlois C, Bieuvelet S, Brochot A, Guilbot A, Clement K, Rizkalla S
    PLoS ONE, 2015;10(9):e0138646.
    Species: Human
    Sample Types: Plasma
  95. Inflammation-regulating factors in ascites as predictive biomarkers of drug resistance and progression-free survival in serous epithelial ovarian cancers.
    Authors: Lane D, Matte I, Garde-Granger P, Laplante C, Carignan A, Rancourt C, Piche A
    BMC Cancer, 2015;15(0):492.
    Species: Human
    Sample Types: Peritoneal Fluid
  96. Leptin levels are negatively correlated with 2-arachidonoylglycerol in the cerebrospinal fluid of patients with osteoarthritis.
    Authors: Nicholson J, Azim S, Rebecchi M, Galbavy W, Feng T, Reinsel R, Rizwan S, Fowler C, Benveniste H, Kaczocha M
    PLoS ONE, 2015;10(4):e0123132.
    Species: Human
    Sample Types: Serum
  97. A cross-over experiment to investigate possible mechanisms for lower BMIs in people who habitually eat breakfast.
    Authors: Reeves S, Huber J, Halsey L, Villegas-Montes M, Elgumati J, Smith T
    Eur J Clin Nutr, 2015;69(5):632-7.
    Species: Human
    Sample Types: Serum
  98. Lower Circulating C1q/TNF-Related Protein-3 (CTRP3) Levels Are Associated with Obesity: A Cross-Sectional Study.
    Authors: Wolf R, Steele K, Peterson L, Magnuson T, Schweitzer M, Wong G
    PLoS ONE, 2015;10(7):e0133955.
    Species: Human
    Sample Types: Serum
  99. Cord blood adipokines, neonatal anthropometrics and postnatal growth in offspring of Hispanic and Native American women with diabetes mellitus.
    Authors: Teague A, Fields D, Aston C, Short K, Lyons T, Chernausek S
    Reprod Biol Endocrinol, 2015;13(0):68.
    Species: Human
    Sample Types: Serum
  100. Additive regulation of adiponectin expression by the mediterranean diet olive oil components oleic Acid and hydroxytyrosol in human adipocytes.
    Authors: Scoditti E, Massaro M, Carluccio M, Pellegrino M, Wabitsch M, Calabriso N, Storelli C, De Caterina R
    PLoS ONE, 2015;10(6):e0128218.
    Species: Human
    Sample Types: Cell Culture Supernates
  101. Regional adipose tissue hormone/cytokine production before and after weight loss in abdominally obese women.
    Authors: You T, Wang X, Murphy K, Lyles M, Demons J, Yang R, Gong D, Nicklas B
    Obesity (Silver Spring), 2014;22(7):1679-84.
    Species: Human
    Sample Types: Plasma
  102. Leptin is associated with vascular endothelial function in overweight patients with type 2 diabetes.
    Authors: Morioka T, Emoto M, Yamazaki Y, Kawano N, Imamura S, Numaguchi R, Urata H, Motoyama K, Mori K, Fukumoto S, Koyama H, Shoji T, Inaba M
    Cardiovasc Diabetol, 2014;13(0):10.
    Species: Human
    Sample Types: Plasma
  103. Serum levels of apoptosis inhibitor of macrophage are associated with hepatic fibrosis in patients with chronic hepatitis C.
    Authors: Mera K, Uto H, Mawatari S, Ido A, Yoshimine Y, Nosaki T, Oda K, Tabu K, Kumagai K, Tamai T, Moriuchi A, Oketani M, Shimada Y, Hidaka M, Eguchi S, Tsubouchi H
    BMC Gastroenterol, 2014;14(0):27.
    Species: Human
    Sample Types: Serum
  104. Brain-derived neurotrophic factor in human subjects with function-altering melanocortin-4 receptor variants.
    Authors: Hohenadel M, Thearle M, Grice B, Huang H, Dai M, Tao Y, Hunter L, Palaguachi G, Mou Z, Kim R, Tsang M, Haack K, Voruganti V, Cole S, Butte N, Comuzzie A, Muller Y, Baier L, Krakoff J, Knowler W, Yanovski J, Han J
    Int J Obes (Lond), 2014;38(8):1068-74.
    Species: Human
    Sample Types: Serum
  105. Short-term intake of a Japanese-style healthy lunch menu contributes to prevention and/or improvement in metabolic syndrome among middle-aged men: a non-randomized controlled trial.
    Authors: Inoue H, Sasaki R, Aiso I, Kuwano T
    Lipids Health Dis, 2014;13(0):57.
    Species: Human
    Sample Types: Serum
  106. Adiponectin is a candidate biomarker of lower extremity bone density in men with chronic spinal cord injury.
    Authors: Doherty A, Battaglino R, Donovan J, Gagnon D, Lazzari A, Garshick E, Zafonte R, Morse L
    J Bone Miner Res, 2014;29(1):251-9.
    Species: Human
    Sample Types: Plasma
  107. The type and quantity of dietary fat and carbohydrate alter faecal microbiome and short-chain fatty acid excretion in a metabolic syndrome 'at-risk' population.
    Authors: Fava, F, Gitau, R, Griffin, B A, Gibson, G R, Tuohy, K M, Lovegrove, J A
    Int J Obes (Lond), 2013;37(2):216-23.
    Species: Human
    Sample Types: Plasma
  108. Association between traffic-related air pollution, subclinical inflammation and impaired glucose metabolism: results from the SALIA study.
    Authors: Teichert T, Vossoughi M, Vierkotter A, Sugiri D, Schikowski T, Schulte T, Roden M, Luckhaus C, Herder C, Kramer U
    PLoS ONE, 2013;8(12):e83042.
    Species: Human
    Sample Types: Plasma
  109. A prospective study of circulating adipokine levels and risk of multiple myeloma.
    Authors: Hofmann J, Liao L, Pollak M, Wang Y, Pfeiffer R, Baris D, Andreotti G, Lan Q, Landgren O, Rothman N, Purdue M
    Blood, 2012;120(22):4418-20.
    Species: Human
    Sample Types: Plasma
  110. Alterations of leptin in the course of inflammation and severe sepsis.
    BMC Infect Dis, 2012;12(0):217.
    Species: Human
    Sample Types: Serum
  111. Effects of dietary fat modification on insulin sensitivity and on other risk factors of the metabolic syndrome-LIPGENE: a European randomized dietary intervention study.
    Authors: Tierney AC, McMonagle J, Shaw DI, Gulseth HL, Helal O, Saris WH, Paniagua JA, Golabek-Leszczynska I, Defoort C, Williams CM, Karsltrom B, Vessby B, Dembinska-Kiec A, Lopez-Miranda J, Blaak EE, Drevon CA, Gibney MJ, Lovegrove JA, Roche HM
    Int J Obes (Lond), 2011;35(6):800-9.
    Species: Human
    Sample Types: Serum
  112. Adipocytokines and CD34 progenitor cells in Alzheimer's disease.
    Authors: Bigalke B, Schreitmuller B, Sopova K, Paul A, Stransky E, Gawaz M, Stellos K, Laske C
    PLoS ONE, 2011;6(5):e20286.
    Species: Human
    Sample Types: Plasma
  113. Improvements in coronary heart disease risk indicators by alternate-day fasting involve adipose tissue modulations.
    Authors: Bhutani S, Klempel MC, Berger RA, Varady KA
    Obesity (Silver Spring), 2010;18(11):2152-9.
    Species: Human
    Sample Types: Plasma
  114. Exenatide affects circulating cardiovascular risk biomarkers independently of changes in body composition.
    Authors: Bunck MC, Diamant M, Eliasson B, Corner A, Shaginian RM, Heine RJ, Taskinen MR, Yki-Jarvinen H, Smith U
    Diabetes Care, 2010;33(8):1734-7.
    Species: Human
    Sample Types: Serum
  115. Differential adaptation of human gut microbiota to bariatric surgery-induced weight loss: links with metabolic and low-grade inflammation markers.
    Authors: Furet JP, Kong LC, Tap J, Poitou C, Basdevant A, Bouillot JL, Mariat D, Corthier G, Dore J, Henegar C, Rizkalla S, Clement K
    Diabetes, 2010;59(12):3049-57.
    Species: Human
    Sample Types: Plasma
  116. Leptin exacerbates sepsis-mediated morbidity and mortality.
    Authors: Shapiro NI, Khankin EV, van Meurs M
    J. Immunol., 2010;185(1):517-24.
    Species: Human
    Sample Types: Plasma
  117. Environmental tobacco smoke and cardiometabolic risk in young children: results from a survey in south-west Germany.
    Authors: Nagel G, Arnold FJ, Wilhelm M, Link B, Zoellner I, Koenig W
    Eur. Heart J., 2009;30(15):1885-93.
    Species: Human
    Sample Types: Plasma
  118. HIV increases markers of cardiovascular risk: results from a randomized, treatment interruption trial.
    Authors: Calmy A, Gayet-Ageron A, Montecucco F, Nguyen A, Mach F, Burger F, Ubolyam S, Carr A, Ruxungtham K, Hirschel B, Ananworanich J,
    AIDS, 2009;23(8):929-39.
    Species: Human
    Sample Types: Plasma
  119. Gene expression profiling of human skeletal muscle in response to stabilized weight loss.
    Authors: Larrouy D, Barbe P, Valle C, Dejean S, Pelloux V, Thalamas C, Bastard JP, Le Bouil A, Diquet B, Clement K, Langin D, Viguerie N
    Am. J. Clin. Nutr., 2008;88(1):125-32.
    Species: Human
    Sample Types: Plasma
  120. Positive energy balance is associated with accelerated muscle atrophy and increased erythrocyte glutathione turnover during 5 wk of bed rest.
    Authors: Biolo G, Agostini F, Simunic B, Sturma M, Torelli L, Preiser JC, Deby-Dupont G, Magni P, Strollo F, di Prampero P, Guarnieri G, Mekjavic IB, Pisot R, Narici MV
    Am. J. Clin. Nutr., 2008;88(4):950-8.
    Species: Human
    Sample Types: Plasma
  121. Retinol-binding protein 4 and lipocalin-2 in childhood and adolescent obesity: when children are not just "small adults".
    Authors: Kanaka-Gantenbein C, Margeli A, Pervanidou P, Sakka S, Mastorakos G, Chrousos GP, Papassotiriou I
    Clin. Chem., 2008;54(7):1176-82.
    Species: Human
    Sample Types: Serum
  122. Absence of leptin resistance in platelets from morbidly obese individuals may contribute to the increased thrombosis risk in obesity.
    Authors: Dellas C, Schafer K, Rohm I, Lankeit M, Ellrott T, Faustin V, Riggert J, Hasenfuss G, Konstantinides S
    Thromb. Haemost., 2008;100(6):1123-9.
    Species: Human
    Sample Types: Plasma
  123. Diurnal variation of human sweet taste recognition thresholds is correlated with plasma leptin levels.
    Authors: Nakamura Y, Sanematsu K, Ohta R, Shirosaki S, Koyano K, Nonaka K, Shigemura N, Ninomiya Y
    Diabetes, 2008;57(10):2661-5.
    Species: Human
    Sample Types: Plasma
  124. Nitrosative stress predicts the presence and severity of nonalcoholic fatty liver at different stages of the development of insulin resistance and metabolic syndrome: possible role of vitamin A intake.
    Authors: Musso G, Gambino R, De Michieli F, Biroli G, Premoli A, Pagano G, Bo S, Durazzo M, Cassader M
    Am. J. Clin. Nutr., 2007;86(3):661-71.
    Species: Human
    Sample Types: Serum
  125. Muscle-specific knockout of PKC-lambda impairs glucose transport and induces metabolic and diabetic syndromes.
    Authors: Farese RV, Sajan MP, Yang H, Li P, Mastorides S, Gower WR, Nimal S, Choi CS, Kim S, Shulman GI, Kahn CR, Braun U, Leitges M
    J. Clin. Invest., 2007;117(8):2289-301.
    Species: Human
    Sample Types: Serum
  126. Obesity, adipokines, and abdominal aortic aneurysm: Health in Men study.
    Authors: Golledge J, Clancy P, Jamrozik K, Norman PE
    Circulation, 2007;116(20):2275-9.
    Species: Human
    Sample Types: Serum
  127. Panel of markers can accurately predict endometriosis in a subset of patients.
    Authors: Seeber B, Sammel MD, Fan X, Gerton GL, Shaunik A, Chittams J, Barnhart KT
    Fertil. Steril., 2007;89(5):1073-81.
    Species: Human
    Sample Types: Serum
  128. The association of gastric leptin with oesophageal inflammation and metaplasia.
    Authors: Francois F, Roper J, Goodman AJ, Pei Z, Ghumman M, Mourad M, de Perez AZ, Perez-Perez GI, Tseng CH, Blaser MJ
    Gut, 2007;57(1):16-24.
    Species: Human
    Sample Types: Serum
  129. The levels of steroid hormones and cytokines in individual follicles are not associated with the fertilization outcome after intracytoplasmic sperm injection.
    Authors: Asimakopoulos B, Abu-Hassan D, Metzen E, Al-Hasani S, Diedrich K, Nikolettos N
    Fertil. Steril., 2007;90(1):60-4.
    Species: Human
    Sample Types: Follicular Fluid
  130. Plasma agouti-related protein levels in women with anorexia nervosa.
    Authors: Moriya J, Takimoto Y, Yoshiuchi K
    Psychoneuroendocrinology, 2006;31(9):1057-61.
    Species: Human
    Sample Types: Plasma
  131. Altered hepatic expression of SREBP-1 and PPARgamma is associated with liver injury in insulin-resistant lipodystrophic HIV-infected patients.
    Authors: Lemoine M, Barbu V, Girard PM, Kim M, Bastard JP, Wendum D, Paye F, Housset C, Capeau J, Serfaty L
    AIDS, 2006;20(3):387-95.
    Species: Human
    Sample Types: Serum
  132. Adiponectin and leptin in maternal serum, cord blood, and breast milk.
    Authors: Weyermann M, Beermann C, Brenner H, Rothenbacher D
    Clin. Chem., 2006;52(11):2095-102.
    Species: Human
    Sample Types: Serum
  133. Adiponectin and other adipocytokines as predictors of markers of triglyceride-rich lipoprotein metabolism.
    Authors: Chan DC, Watts GF, Ng TW, Uchida Y, Sakai N, Yamashita S, Barrett PH
    Clin. Chem., 2005;51(3):578-85.
    Species: Human
    Sample Types: Plasma
  134. Genetic regulation of the variation of circulating insulin-like growth factors and leptin in human pedigrees.
    Authors: Pantsulaia Ia, Pantsulaia I, Trofimov S, Kobyliansky E, Livshits G
    Metab. Clin. Exp., 2005;54(7):975-81.
    Species: Human
    Sample Types: Plasma
  135. Enhanced monocyte chemoattractant protein-3/CC chemokine ligand-7 in usual interstitial pneumonia.
    Authors: Choi ES, Jakubzick C, Carpenter KJ, Kunkel SL, Evanoff H, Martinez FJ, Flaherty KR, Toews GB, Colby TV, Kazerooni EA, Gross BH, Travis WD, Hogaboam CM
    Am. J. Respir. Crit. Care Med., 2004;170(5):508-15.
    Species: Human
    Sample Types: Cell Culture Supernates
  136. Determinants of plasma leptin concentration in postmenopausal women.
    Authors: Brooks-Asplund EM, Tupper CE, Daun JM, Kenney WL, Cannon JG
    Mech. Ageing Dev., 2004;125(2):117-9.
    Species: Human
    Sample Types:

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Human Leptin Quantikine ELISA Kit
By Anonymous on 11/14/2022
Sample Tested: Serum

Human Leptin Quantikine ELISA Kit
By Anonymous on 05/25/2022
Sample Tested: EDTA Plasma

Human Leptin Quantikine ELISA Kit
By Anonymous on 05/20/2022
Sample Tested: EDTA Plasma,Serum

Human Leptin Quantikine ELISA Kit
By Anonymous on 01/31/2022
Sample Tested: Serum

Human Leptin Quantikine ELISA Kit
By Anonymous on 01/14/2022
Sample Tested: Serum

Human Leptin Quantikine ELISA Kit
By Anonymous on 01/27/2021
Sample Tested: Serum

Human Leptin Quantikine ELISA Kit
By Anonymous on 01/25/2021
Sample Tested: Serum

Per usual, R&D kit was easy to use and straight forward. Produced great results.


Human Leptin Quantikine ELISA Kit
By Kimberly Steen on 01/22/2021
Sample Tested: EDTA Plasma

Product preformed well- instructions were clear, included detailed background, and the reagent was easy to prepare.


Human Leptin Quantikine ELISA Kit
By Anonymous on 05/15/2017
Sample Tested: Human serum