Human Leptin ELISA Kit - Quantikine

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Human Leptin/OB ELISA Standard Curve
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Human Leptin Quantikine ELISA Kit Summary

Assay Type
Solid Phase Sandwich ELISA
Format
96-well strip plate
Assay Length
3.5 hours
Sample Type & Volume Required Per Well
Cell Culture Supernates (100 uL), Serum (10 uL), EDTA Plasma (10 uL), Heparin Plasma (10 uL), Citrate Plasma (10 uL)
Sensitivity
7.8 pg/mL
Assay Range
15.6 - 1,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma)
Specificity
Natural and recombinant human Leptin
Cross-reactivity
< 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
Interference
Interference observed with 1 or more available related molecules.

Sample Values

Serum - Samples from apparently healthy volunteers were evaluated for the presence of human Leptin in this assay. No medical histories were available for the donors used in this study.

Sample TypeRange (pg/mL)Mean (pg/mL)
Male Serum (n=16)2205-11,4194760
Female Serum (n=36)3877-77,27320,676

Five additional male serum samples fell below the lowest standard,15.6 pg/mL, when diluted 100-fold.

Note: Values in EDTA and heparin plasma have been found to be comparable to paired serum samples. Values in citrate plasma have been found to be slightly decreased compared to paired serum, EDTA or heparin plasma samples.

Cell Culture Supernates:
Human peripheral blood mononuclear cells (5 x 106 cells/mL) were cultured in RPMI supplemented with 5% fetal bovine serum, 50 μM beta -mercaptoethanol, 2 mM L-glutamine, 100 U/mL penicillin, and 100 μg/mL streptomycin sulfate. The cells were cultured unstimulated or stimulated with 10 μg/mL PHA. Aliquots of the cell culture supernates were removed on days 1 and 5 and assayed for levels of human Leptin.

ConditionDay 1(pg/mL)Day 5 (pg/mL)
UnstimulatedNDND
Stimulated15275.9
ND=Non-detectable

BeWo human choriocarcinoma cells (1 x 106 cells/mL) were cultured in F-12 media supplemented with 15% fetal bovine serum. The cells were cultured unstimulated or stimulated with 2 μM forskolin and 20 μM forskolin. Aliquots of the cell culture supernates were removed on days 1, 2, and 3 and assayed for levels of human Leptin.

ConditionDay 1 (pg/mL)Day 2 (pg/mL)Day 3 (pg/mL)
Unstimulated*84915491667
2 μM forskolin*123116992054
20 μM forskolin*113717252747
*Samples were dilluted 20-fold prior to assay.



Product Summary

The Quantikine Human Leptin Immunoassay is a 3.5 hour solid phase ELISA designed to measure soluble human Leptin in cell culture supernates, serum, and plasma. It contains E. coli-expressed recombinant human Leptin and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate recombinant Leptin accurately. Results obtained measuring natural human Leptin showed dose-response curves that were parallel to the standard curves obtained using the recombinant Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural human Leptin.

Precision

Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision

Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma

Intra-Assay Precision Inter-Assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 40 40 40
Mean (pg/mL) 64.5 146 621 65.7 146 581
Standard Deviation 2.14 4.32 20 3.56 6.17 20.6
CV% 3.3 3 3.2 5.4 4.2 3.5

Recovery

The recovery of Leptin spiked to three different levels throughout the range of the assay in various matrices was evaluated.

Sample Type Average % Recovery Range %
Cell Culture Media (n=5) 98 94-102
Citrate Plasma (n=5) 95 87-105
EDTA Plasma (n=5) 99 85-112
Heparin Plasma (n=5) 90 81-100
Serum (n=5) 95 89-109

Linearity

To assess the linearity of the assay, cell culture media samples spiked with high concentrations of Leptin and natural serum/plasma samples were diluted with Calibrator Diluent to produce samples with values within the dynamic range of the assay.
Human Leptin/OB ELISA Linearity

Scientific Data

Human Leptin/OB ELISA Standard Curve

Product Datasheets

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Preparation and Storage

Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: Leptin/OB

Leptin is a product of the mouse obese gene. Mice with mutations in the obese gene that block the synthesis of leptin are obese and diabetic, and have reduced activity, metabolism, and body temperature. Rat leptin shares approximately 96% and 82% sequence identity with the mouse and human protein, respectively. The expression of leptin mRNA is restricted to adipose tissue.

Entrez Gene IDs:
3952 (Human); 16846 (Mouse); 25608 (Rat)
Alternate Names:
FLJ94114; LEP; leptin (murine obesity homolog); leptin (obesity homolog, mouse); Leptin; OB; Obese protein; obese, mouse, homolog of; Obesity factor; OBOBS
&#9888; WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Assay Procedure

Refer to the product for complete assay procedure.

Bring all reagents and samples to room temperature before use. It is recommended that all samples, standards, and controls be assayed in duplicate.
  1.   Prepare all reagents, standard dilutions, and samples as directed in the product insert.
  2.   Remove excess microplate strips from the plate frame, return them to the foil pouch containing the desiccant pack, and reseal.

  3. 100 µL Assay Diluent
  4.   Add 100 µL of Assay Diluent to each well.

  5. 100 µL Standard, Control, or Sample
  6.   Add 100 µL of Standard, control, or sample to each well. Cover with a plate sealer, and incubate at room temperature for 2 hours.
  7.   Aspirate each well and wash, repeating the process 3 times for a total of 4 washes.

  8. 200 µL Conjugate
  9.   Add 200 µL of Conjugate to each well. Cover with a new plate sealer, and incubate at room temperature for 1 hour.
  10.   Aspirate and wash 4 times.

  11. 200 µL Substrate Solution
  12.   Add 200 µL Substrate Solution to each well. Incubate at room temperature for 30 minutes. PROTECT FROM LIGHT.

  13. 50 µL Stop Solution
  14.   Add 50 µL of Stop Solution to each well. Read at 450 nm within 30 minutes. Set wavelength correction to 540 nm or 570 nm.

Citations for Human Leptin Quantikine ELISA Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

149 Citations: Showing 1 - 10
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  1. Bronchoalveolar cytokine profile differentiates Pulmonary Langerhans cell histiocytosis patients from other smoking-related interstitial lung diseases
    Authors: Barril, S;Acebo, P;Millan-Billi, P;Luque, A;Sibila, O;Tarín, C;Tazi, A;Castillo, D;Hortelano, S;
    Respiratory research
    Species: Human
    Sample Types: BALF
  2. Metabolic Syndrome and Adipokines Profile in Bipolar Depression
    Authors: Bilska, K;Dmitrzak-W?glarz, M;Osip, P;Pawlak, J;Paszy?ska, E;Permoda-Pachuta, A;
    Nutrients
    Species: Human
    Sample Types: Serum
  3. Novel Multi-Ingredient Supplement Facilitates Weight Loss and Improves Body Composition in Overweight and Obese Individuals: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
    Authors: Nederveen, JP;Mastrolonardo, AJ;Xhuti, D;Di Carlo, A;Manta, K;Fuda, MR;Tarnopolsky, MA;
    Nutrients
    Species: Human
    Sample Types: Plasma
  4. Associations of three thermogenic adipokines with metabolic syndrome in obese and non-obese populations from the China plateau: the China Multi-Ethnic Cohort
    Authors: Zhao, Z;Huang, J;Zhong, D;Wang, Y;Che, Z;Xu, Y;Hong, R;Qian, Y;Meng, Q;Yin, J;
    BMJ open
    Species: Human
    Sample Types: Plasma
  5. Changes in objectively measured sleep after a multidisciplinary lifestyle intervention in children with abdominal obesity: A randomized trial
    Authors: Catalán-Lambán, A;Ojeda-Rodríguez, A;Marti Del Moral, A;Azcona-Sanjulian, C;
    Sleep medicine
    Species:  Human
    Sample Types: Serum
  6. A single nuclei atlas of aging human abdominal subcutaneous white adipose tissue
    Authors: Sparks, L;Whytock, K;Divoux, A;Sun, Y;Pino, M;Yu, G;Smith, S;Walsh, M;
    Research square
    Species: Human
    Sample Types: Cell Culture Supernates
  7. Association of inflammatory biomarkers and disease activity with subclinical myocardial dysfunction in psoriatic arthritis
    Authors: Pletikosic, I;Marasovic Krstulovic, D;Bakovic, D;Susilovic Grabovac, Z;Tandara, L;Martinovic Kaliterna, D;
    Scientific reports
    Species: Human
    Sample Types: Serum
  8. Metformin Treatment of Hidradenitis Suppurativa: Effect on Metabolic Parameters, Inflammation, Cardiovascular Risk Biomarkers, and Immune Mediators
    Authors: R Hambly, N Kearney, R Hughes, JM Fletcher, B Kirby
    International Journal of Molecular Sciences, 2023-04-09;24(8):.
    Species: Human
    Sample Types: Serum
  9. Comparison of Diagnostic Models to Estimate the Risk of Metabolic Syndrome in a Chilean Pediatric Population: A Cross-Sectional Study
    Authors: M Solorzano, G Granfeldt, N Ulloa, G Molina-Rec, R Molina-Luq, C Aguayo, F Petermann-, M Martorell
    Metabolites, 2023-02-16;13(2):.
    Species: Human
    Sample Types: Serum
  10. Postnatal Leptin Levels Correlate with Breast Milk Leptin Content in Infants Born before 32 Weeks Gestation
    Authors: T Chatmethak, ML Schmelzel, KJ Johnson, JR Walker, DA Santillan, TT Colaizy, RD Roghair
    Nutrients, 2022-12-08;14(24):.
    Species: Human
    Sample Types: Plasma
  11. Leptin-producing monocytes in the airway submucosa may contribute to asthma pathogenesis
    Authors: K Watanabe, M Suzukawa, S Kawauchi-W, S Igarashi, I Asari, S Imoto, H Tashimo, T Fukami, A Hebisawa, S Tohma, T Nagase, K Ohta
    Respiratory investigation, 2022-11-09;0(0):.
    Species: Human
    Sample Types: Serum
  12. Association of serum leptin at 24-28�weeks gestation with initiation and progression of labor in women
    Authors: KKR Branham, E Sherman, M Golzy, EZ Drobnis, LC Schulz
    Scientific Reports, 2022-09-26;12(1):16016.
    Species: Human
    Sample Types: Serum
  13. Inflammatory and metabolic markers in relation to outcome of in vitro fertilization in a cohort of predominantly overweight and obese women
    Authors: H Svensson, S Einarsson, D Olausson, L Kluge, C Bergh, S Edén, M Lönn, A Thurin-Kje
    Scientific Reports, 2022-08-03;12(1):13331.
    Species: Human
    Sample Types: Serum
  14. Serum and Adipose Dipeptidyl Peptidase 4 in Cardiovascular Surgery Patients: Influence of Dipeptidyl Peptidase 4 Inhibitors
    Authors: I Shibasaki, T Nakajima, T Fukuda, T Hasegawa, H Ogawa, G Tsuchiya, Y Takei, M Tezuka, T Kato, Y Kanazawa, Y Kano, T Kuwata, M Ouchi, S Toyoda, Y Aso, H Fukuda
    Journal of Clinical Medicine, 2022-07-26;11(15):.
    Species: Human
    Sample Types: Serum
  15. Influence of NAFLD and bariatric surgery on hepatic and adipose tissue mitochondrial biogenesis and respiration
    Authors: JS Pedersen, MO Rygg, K Chrøis, EG Sustarsic, Z Gerhart-Hi, NJ Wever Albr, RR Serizawa, VB Kristianse, AL Basse, AEB Boilesen, BH Olsen, T Hansen, LL Gluud, S Madsbad, S Larsen, F Bendtsen, F Dela
    Nature Communications, 2022-05-25;13(1):2931.
    Species: Human
    Sample Types: Plasma
  16. Plasma concentration of Bisphenol A and leptin in patients with meningioma and glioma: A pilot study
    Authors: M Komarowska, R Chrzanowsk, M Tylicka, R Rutkowski, Z Mariak, B Zelazowska, T Lyson, A Hermanowic
    Advances in medical sciences, 2022-05-17;67(2):229-233.
    Species: Human
    Sample Types: Plasma
  17. Relationship between metabolic syndrome and follicle-stimulating hormone in postmenopausal women
    Authors: SW Lee, IS Hwang, G Jung, HJ Kang, YH Chung
    Medicine, 2022-05-06;101(18):e29216.
    Species: Human
    Sample Types: Serum
  18. Preventing White Adipocyte Browning during Differentiation In Vitro: The Effect of Differentiation Protocols on Metabolic and Mitochondrial Phenotypes
    Authors: E Herbers, M Patrikoski, A Wagner, R Jokinen, A Hassinen, S Heinonen, S Miettinen, H Peltoniemi, E Pirinen, KH Pietiläine
    Stem Cells International, 2022-04-05;2022(0):3308194.
    Species: Human
    Sample Types: Cell Culture Supernates
  19. The beneficial effects of intradialytic parenteral nutrition in hemodialysis patients with protein energy wasting: a prospective randomized controlled trial
    Authors: P Kittiskuln, A Banjongjit, K Metta, K Tiranathan, Y Avihingsan, K Praditporn, K Tungsanga, S Eiam-Ong
    Scientific Reports, 2022-03-16;12(1):4529.
    Species: Human
    Sample Types: Plasma
  20. Leptin-mediated proinflammatory bone marrow environment in acquired aplastic anemia
    Authors: M Gao, M Ge, J Huo, X Ren, X Li, Y Shao, J Huang, J Zhang, M Wang, N Nie, P Jin, Y Zheng
    Cytokine, 2022-02-23;152(0):155829.
    Species: Human
    Sample Types: Cell Culture Supernates
  21. Changes in adipokine levels and metabolic profiles following bariatric surgery
    Authors: N Šebunova, J Štšepetova, T Kullisaar, K Suija, A Rätsep, I Junkin, H Soeorg, M Lember, T Sillakivi, R Mändar
    BMC endocrine disorders, 2022-02-03;22(1):33.
    Species: Human
    Sample Types: Serum
  22. Relationship between Epicardial and Coronary Adipose Tissue and the Expression of Adiponectin, Leptin, and Interleukin 6 in Patients with Coronary Artery Disease
    Authors: OV Gruzdeva, YA Dyleva, EV Belik, MY Sinitsky, AN Stasev, AN Kokov, NK Brel, EO Krivkina, EE Bychkova, RS Tarasov, OL Barbarash
    Journal of personalized medicine, 2022-01-19;12(2):.
    Species: Human
    Sample Types: Cell Culture Media
  23. Roles of plasma leptin and resistin in novel subgroups of type 2 diabetes driven by cluster analysis
    Authors: X Peng, J Huang, H Zou, B Peng, S Xia, K Dong, N Sun, J Tao, Y Yang
    Lipids in Health and Disease, 2022-01-07;21(1):7.
    Species: Human
    Sample Types: Plasma
  24. Serum Leptin Levels, Nutritional Status, and the Risk of Healthcare-Associated Infections in Hospitalized Older Adults
    Authors: E Paillaud, J Poisson, C Granier, A Ginguay, A Plonquet, C Conti, A Broussier, A Raynaud-Si, S Bastuji-Ga
    Nutrients, 2022-01-05;14(1):.
    Species: Human
    Sample Types: Serum
  25. The Contribution of the Hunger Hormone Leptin in the Aetiology of Postoperative Anorexia after Laparoscopic and Open Gastrectomy in Gastric Cancer Patients
    Authors: T Jagric
    Biomolecules, 2021-10-29;11(11):.
    Species: Human
    Sample Types: Serum
  26. Improvement of Inflammation and Pain after Three Months' Exclusion Diet in Rheumatoid Arthritis Patients
    Authors: MT Guagnano, C D'Angelo, D Caniglia, P Di Giovann, E Celletti, E Sabatini, L Speranza, M Bucci, F Cipollone, R Paganelli
    Nutrients, 2021-10-09;13(10):.
    Species: Human
    Sample Types: Serum
  27. Exploring the Mechanisms of Recovery in Anorexia Nervosa through a Translational Approach: From Original Ecological Measurements in Human to Brain Tissue Analyses in Mice
    Authors: P Duriez, IAK Nilsson, O Le Thuc, D Alexandre, N Chartrel, C Rovere, C Chauveau, P Gorwood, V Tolle, O Viltart
    Nutrients, 2021-08-13;13(8):.
    Species: Human
    Sample Types: Plasma
  28. The Role of Leptin in Childhood Immune Thrombocytopenia (ITP): An Anti-Inflammatory Agent?
    Authors: I Thomas, I Panagoulia, I Aggeletopo, A Varvarigou, BE Spiliotis, A Mouzaki
    International Journal of Molecular Sciences, 2021-07-16;22(14):.
    Species: Mouse
    Sample Types: Plasma
  29. Adiponectin as a novel biomarker of disease severity in alopecia areata
    Authors: A Stochmal, A Wa?kiel-Bu, S Chrostowsk, M Zaremba, A Rakowska, J Czuwara, L Rudnicka
    Scientific Reports, 2021-07-05;11(1):13809.
    Species: Human
    Sample Types: Serum
  30. Physical activity during pregnancy and association with changes in fat mass and adipokines in women of normal-weight or with obesity
    Authors: U Andersson-, H de Maré, F Askeli, M Börjesson, A Holmäng
    Scientific Reports, 2021-06-15;11(1):12549.
    Species: Human
    Sample Types: Serum
  31. High-throughput drug screening models of mature adipose tissues which replicate the physiology of patients' Body Mass Index (BMI)
    Authors: F Louis, Y Sowa, S Kitano, M Matsusaki
    Bioactive materials, 2021-05-30;7(0):227-241.
    Species: Human
    Sample Types: Cell Culture Supernates
  32. Biomarkers of Oncogenesis, Adipose Tissue Dysfunction and Systemic Inflammation for the Detection of Hepatocellular Carcinoma in Patients with Nonalcoholic Fatty Liver Disease
    Authors: GP Caviglia, A Armandi, C Rosso, S Gaia, S Aneli, E Rolle, ML Abate, A Olivero, A Nicolosi, M Guariglia, DG Ribaldone, P Carucci, GM Saracco, E Bugianesi
    Cancers, 2021-05-11;13(10):.
    Species: Human
    Sample Types: Plasma
  33. Sex differences in the relationship between body composition and biomarkers of bone and fat metabolism in obese boys and girls
    Authors: R Khwanchuea, C Punsawad
    Bone Reports, 2021-05-04;14(0):101087.
    Species: Human
    Sample Types: Serum
  34. AntiTNF-alpha therapy normalizes levels of lipids and adipokines in psoriatic patients in the real-life settings
    Authors: I Olejniczak, J Narbutt, J Ceryn, M Skibi?ska, I Bednarski, A Wo?niacka, J Sieniawska, M Kraska-Gac, M Ci??y?ska, J ?migielski, M Noweta, M Waszczykow, W Owczarek, A Reich, A Lesiak
    Scientific Reports, 2021-04-29;11(1):9289.
    Species: Human
    Sample Types: Serum
  35. Level of Adiponectin, Leptin and Selected Matrix Metalloproteinases in Female Overweight Patients with Primary Gonarthrosis
    Authors: J Jarecki, T Ma?ecka-Ma, I Polkowska, B Potoczniak, E Kosior-Jar, I Szerb, E Tomaszewsk, M Gutbier, M Dobrzy?ski, T Blicharski
    Journal of Clinical Medicine, 2021-03-18;10(6):.
    Species: Human
    Sample Types: Serum
  36. Expression of adipocytokines in heart fat depots depending on the degree of coronary artery atherosclerosis in patients with coronary artery disease
    Authors: OV Gruzdeva, EV Belik, YA Dyleva, DA Borodkina, MY Sinitsky, DY Naumov, EE Bychkova, EV Fanaskova, EI Palicheva, AA Kuzmina, VN Karetnikov, OL Barbarash
    PLoS ONE, 2021-03-18;16(3):e0248716.
    Species: Human
    Sample Types: Tissue Homogenates
  37. Epigenetic Regulation of Processes Related to High Level of Fibroblast Growth Factor 21 in Obese Subjects
    Authors: T P?atek, A Polus, J Góralska, U Ra?ny, A Dziewo?ska, A Micek, A Dembi?ska-, B Solnica, M Malczewska
    Genes, 2021-02-21;12(2):.
    Species: Human
    Sample Types: Serum
  38. Adipocytokines in Untreated Newly Diagnosed Rheumatoid Arthritis: Association with Circulating Chemokines and Markers of Inflammation
    Authors: GK Vasileiadi, AC Lundell, Y Zhang, K Andersson, I Gjertsson, A Rudin, C Maglio
    Biomolecules, 2021-02-21;11(2):.
    Species: Human
    Sample Types: Plasma
  39. Lactobacillus plantarum 299v probiotic supplementation in men with stable coronary artery disease suppresses systemic inflammation
    Authors: BC Hofeld, VK Puppala, S Tyagi, KW Ahn, A Anger, S Jia, NH Salzman, MJ Hessner, ME Widlansky
    Scientific Reports, 2021-02-17;11(1):3972.
    Species: Human
    Sample Types: Plasma
  40. Association of Maternal Microbiota and Diet in Cord Blood Cytokine and Immunoglobulin Profiles
    Authors: K Rio-Aige, I Azagra-Bor, M Massot-Cla, M Selma-Royo, A Parra-Llor, S González, I García-Man, M Castell, MJ Rodríguez-, MC Collado, FJ Pérez Cano
    International Journal of Molecular Sciences, 2021-02-10;22(4):.
    Species: Human
    Sample Types: Plasma
  41. Association of serum adiponectin and myostatin levels with skeletal muscle in patients with obesity: A cross-sectional study
    Authors: S Kurose, K Onishi, N Takao, T Miyauchi, K Takahashi, Y Kimura
    PLoS ONE, 2021-01-19;16(1):e0245678.
    Species: Human
    Sample Types: Serum
  42. Pain in women with knee and/or hip osteoarthritis is related to systemic inflammation and to adipose tissue dysfunction: Cross-sectional results of the KHOALA cohort
    Authors: J Sellam, AC Rat, S Fellahi, JP Bastard, W Ngueyon Si, HK Ea, X Chevalier, P Richette, J Capeau, F Guillemin, F Berenbaum
    Seminars in arthritis and rheumatism, 2020-12-18;51(1):129-136.
    Species: Human
    Sample Types: Serum
  43. The Link between Obesity and Inflammatory Markers in the Development of Type 2 Diabetes in Men of Black African and White European Ethnicity
    Authors: O Hakim, O Bello, M Ladwa, JL Peacock, AM Umpleby, G Charles-Ed, SA Amiel, LM Goff
    Nutrients, 2020-12-11;12(12):.
    Species: Human
    Sample Types: Plasma
  44. APOE-&epsilon4-related differences in left thalamic microstructure in cognitively healthy adults
    Authors: JP Mole, F Fasano, J Evans, R Sims, E Kidd, JP Aggleton, C Metzler-Ba
    Sci Rep, 2020-11-13;10(1):19787.
    Species: Human
    Sample Types: Plasma
  45. Influence of Short-Term Hyperenergetic, High-Fat Feeding on Appetite, Appetite-Related Hormones, and Food Reward in Healthy Men
    Authors: AE Thackray, SA Willis, DJ Clayton, DR Broom, G Finlayson, FR Goltz, JA Sargeant, RM Woods, DJ Stensel, JA King
    Nutrients, 2020-08-29;12(9):.
    Species: Human
    Sample Types: Plasma
  46. Monounsaturated fat rapidly induces hepatic gluconeogenesis and whole-body insulin resistance
    Authors: T Sarabhai, S Kahl, J Szendroedi, DF Markgraf, OP Zaharia, C Barosa, C Herder, F Wickrath, P Bobrov, JH Hwang, JG Jones, M Roden
    JCI Insight, 2020-05-21;5(10):.
    Species: Human
    Sample Types: Serum
  47. Statin therapy is associated with lower prevalence of gut microbiota dysbiosis
    Authors: S Vieira-Sil, G Falony, E Belda, T Nielsen, J Aron-Wisne, R Chakaroun, SK Forslund, K Assmann, M Valles-Col, TTD Nguyen, S Proost, E Prifti, V Tremaroli, N Pons, E Le Chateli, F Andreelli, JP Bastard, LP Coelho, N Galleron, TH Hansen, JS Hulot, C Lewinter, HK Pedersen, B Quinquis, C Rouault, H Roume, JE Salem, NB Søndertoft, S Touch, ME Dumas, SD Ehrlich, P Galan, JP Gøtze, T Hansen, JJ Holst, L Køber, I Letunic, J Nielsen, JM Oppert, M Stumvoll, H Vestergaar, JD Zucker, P Bork, O Pedersen, F Bäckhed, K Clément, J Raes
    Nature, 2020-05-06;581(7808):310-315.
    Species: Human
    Sample Types: Serum
  48. Chronic mirabegron treatment increases human brown fat, HDL cholesterol, and insulin sensitivity
    Authors: AE O'Mara, JW Johnson, JD Linderman, RJ Brychta, S McGehee, LA Fletcher, YA Fink, D Kapuria, TM Cassimatis, N Kelsey, C Cero, Z Abdul-Sate, F Piccinini, AS Baskin, BP Leitner, H Cai, CM Millo, W Dieckmann, M Walter, NB Javitt, Y Rotman, PJ Walter, M Ader, RN Bergman, P Herscovitc, KY Chen, AM Cypess
    J. Clin. Invest., 2020-05-01;0(0):.
    Species: Human
    Sample Types: Plasma
  49. SIV Infection and the HIV Proteins Tat and Nef Induce Senescence in Adipose Tissue and Human Adipose Stem Cells, Resulting in Adipocyte Dysfunction
    Authors: J Gorwood, T Ejlalmanes, C Bourgeois, M Mantecon, C Rose, M Atlan, D Desjardins, R Le Grand, B Fève, O Lambotte, J Capeau, V Béréziat, C Lagathu
    Cells, 2020-04-01;9(4):.
    Species: Human
    Sample Types: Cell Culture Supernates
  50. Effects of underfeeding and oral vancomycin on gut microbiome and nutrient absorption in humans
    Authors: A Basolo, M Hohenadel, QY Ang, P Piaggi, S Heinitz, M Walter, P Walter, S Parrington, DD Trinidad, RJ von Schwar, PJ Turnbaugh, J Krakoff
    Nat. Med., 2020-03-23;26(4):589-598.
    Species: Human
    Sample Types: Plasma
  51. Circulating leptin levels are associated with adiposity in survivors of childhood brain tumors
    Authors: ED Sims, WJ Jennings, B Empringham, A Fleming, C Portwine, DL Johnston, SM Zelcer, SR Rassekh, S Burrow, L Thabane, MC Samaan
    Sci Rep, 2020-03-13;10(1):4711.
    Species: Human
    Sample Types: Plasma
  52. Associations between prenatal serum levels of leptin, IGF-I, and estradiol and adolescent mothers' height gain during and after pregnancy
    Authors: R Sámano, H Martínez-R, G Chico-Barb, M Hernández-, R Guzmán, G Arteaga-Tr, MA Figueroa-P, RM Morales, G Martínez
    PLoS ONE, 2020-02-11;15(2):e0228706.
    Species: Human
    Sample Types: Serum
  53. Association of serum leptin and adiponectin concentrations with echocardiographic parameters and pathophysiological states in patients with cardiovascular disease receiving cardiovascular surgery
    Authors: T Sawaguchi, T Nakajima, A Haruyama, T Hasegawa, I Shibasaki, T Nakajima, H Kaneda, T Arikawa, S Obi, M Sakuma, H Ogawa, Y Takei, S Toyoda, F Nakamura, S Abe, H Fukuda, T Inoue
    PLoS ONE, 2019-11-08;14(11):e0225008.
    Species: Human
    Sample Types: Serum
  54. Association between genetically determined leptin and blood lipids considering alcohol consumption: a Mendelian randomisation study
    Authors: L Shen, JF Cordero, JS Wang, Y Shen, S Li, L Liang, Z Zou, C Li
    BMJ Open, 2019-11-07;9(11):e026860.
    Species: Human
    Sample Types: Serum
  55. Breast Milk Supply of MicroRNA Associated with Leptin and Adiponectin Is Affected by Maternal Overweight/Obesity and Influences Infancy BMI
    Authors: R Zamanillo, J Sánchez, F Serra, A Palou
    Nutrients, 2019-10-28;11(11):.
    Species: Human
    Sample Types: Milk
  56. Biological variation of immunological blood biomarkers in healthy individuals and quality goals for biomarker tests
    Authors: N Aziz, R Detels, JJ Quint, D Gjertson, T Ryner, AW Butch
    BMC Immunol., 2019-09-14;20(1):33.
    Species: Human
    Sample Types: Serum
  57. Hormonal, metabolic and inflammatory circulating biomarker profiles in obese and non-obese Brazilian middle-aged women
    Authors: LV Galvão-Mor, ACB Nascimento, IMSC D'Albuquer, MAS Sousa, HO Brito, MDDSB Nascimento, MB da Costa C, LMO Brito
    PLoS ONE, 2019-09-11;14(9):e0222239.
    Species: Human
    Sample Types: Serum
  58. Multilevel defects in the hematopoietic niche in essential thrombocythemia
    Authors: T Sun, M Ju, X Dai, H Dong, W Gu, Y Gao, R Fu, X Liu, Y Huang, W Liu, Y Chi, W Wang, H Li, Y Zhou, L Shi, R Yang, L Zhang
    Haematologica, 2019-07-09;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  59. Long Pentraxin 3 as a Broader Biomarker for Multiple Risk Factors in End-Stage Renal Disease: Association with All-Cause Mortality
    Authors: MJ Valente, S Rocha, S Coimbra, C Catarino, P Rocha-Pere, E Bronze-da-, JG Oliveira, J Madureira, JC Fernandes, M do Sameiro, V Miranda, L Belo, A Santos-Sil
    Mediators Inflamm., 2019-06-16;2019(0):3295725.
    Species: Human
    Sample Types: Plasma
  60. Maternal pre-pregnancy weight status modifies the influence of PUFAs and inflammatory biomarkers in breastmilk on infant growth
    Authors: H Nuss, A Altazan, J Zabaleta, M Sothern, L Redman
    PLoS ONE, 2019-05-29;14(5):e0217085.
    Species: Human
    Sample Types: Serum
  61. High- or moderate-intensity training promotes change in cardiorespiratory fitness, but not visceral fat, in obese men: A randomised trial of equal energy expenditure exercise
    Authors: J Gerosa-Net, VLG Panissa, PA Monteiro, DS Inoue, JPJ Ribeiro, C Figueiredo, AM Zagatto, JP Little, FS Lira
    Respir Physiol Neurobiol, 2019-05-21;266(0):150-155.
    Species: Human
    Sample Types: Serum
  62. Lower levels of leptin are associated with severity parameters in visceral leishmaniasis patients
    Authors: AMDC Fievez, ML Silva-Frei, AQ Sousa, JR Santos-Oli, AM Da-Cruz
    PLoS ONE, 2019-03-26;14(3):e0214413.
    Species: Human
    Sample Types: Serum
  63. The effect of resistance exercise upon age-related systemic and local skeletal muscle inflammation
    Authors: AK Ziegler, SM Jensen, P Schjerling, AL Mackey, JL Andersen, M Kjaer
    Exp. Gerontol., 2019-03-21;121(0):19-32.
    Species: Human
    Sample Types: Serum
  64. Sex difference in the mediation roles of an inflammatory factor (hsCRP) and adipokines on the relationship between adiposity and blood pressure
    Authors: YD Yang, CJ Zheng, YH Dong, ZY Zou, Y Lv, ZH Wang, ZG Yang, S Wang, B Dong, J Ma
    Hypertens. Res., 2019-02-28;0(0):.
    Species: Human
    Sample Types: Serum
  65. FABP4 in Gestational Diabetes-Association between Mothers and Offspring
    Authors: J Patro-Ma?y, M Trojnar, ? Kimber-Tro, R Mierzy?ski, J Bartosiewi, J Oleszczuk, B Leszczy?sk
    J Clin Med, 2019-02-27;8(3):.
    Species: Human
    Sample Types: Serum
  66. Daily walnut intake improves metabolic syndrome status and increases circulating adiponectin levels: randomized controlled crossover trial
    Authors: HJ Hwang, Y Liu, HS Kim, H Lee, Y Lim, H Park
    Nutr Res Pract, 2019-02-11;13(2):105-114.
    Species: Human
    Sample Types: Serum
  67. Developmental trajectories of body mass index from childhood into late adolescence and subsequent late adolescence-young adulthood cardiometabolic risk markers
    Authors: K Oluwagbemi, AE Buyken, U Alexy, M Schmid, C Herder, U Nöthlings
    Cardiovasc Diabetol, 2019-01-19;18(1):9.
    Species: Human
    Sample Types: Plasma
  68. Inter-ictal assay of peripheral circulating inflammatory mediators in migraine patients under adjunctive cervical non-invasive vagus nerve stimulation (nVNS): A proof-of-concept study
    Authors: SR Chaudhry, IS Lendvai, S Muhammad, P Westhofen, J Kruppenbac, L Scheef, H Boecker, D Scheele, R Hurlemann, TM Kinfe
    Brain Stimul, 2019-01-19;0(0):.
    Species: Human
    Sample Types: Serum
  69. Serum CA125 and ascites leptin level ratio predicts baseline clinical resistance to first-line platinum-based treatment and poor prognosis in patients with high grade serous ovarian cancer
    Authors: I Matte, P Garde-Gran, P Bessette, A Piché
    Am J Cancer Res, 2019-01-01;9(1):160-170.
    Species: Human
    Sample Types: Ascites Fluid
  70. Fasting plasma mannose levels are associated with insulin sensitivity independent of BMI in Japanese individuals with diabetes
    Authors: E Amano, S Funakoshi, K Yoshimura, S Hirano, S Ohmi, H Takata, Y Terada, S Fujimoto
    Diabetol Metab Syndr, 2018-12-04;10(0):88.
    Species: Human
    Sample Types: Serum
  71. The circulating metabolome of human starvation
    Authors: ML Steinhause, BA Olenchock, J O'Keefe, M Lun, KA Pierce, H Lee, L Pantano, A Klibanski, GI Shulman, CB Clish, PK Fazeli
    JCI Insight, 2018-08-23;3(16):.
    Species: Human
    Sample Types: Plasma
  72. Differences in biochemical markers between Heart-transplanted and Left Ventricular Assist Device implanted patients, during cardiac rehabilitation
    Authors: V Racca, P Castiglion, C Panzarino, M Saresella, I Marventano, A Verde, F Oliva, M Ferratini
    Sci Rep, 2018-07-17;8(1):10816.
    Species: Human
    Sample Types: Serum
  73. The impact of human breast milk components on the infant metabolism
    Authors: C Hellmuth, O Uhl, H Demmelmair, M Grunewald, R Auricchio, G Castillejo, IR Korponay-S, I Polanco, M Roca, SL Vriezinga, KJ Werkstette, B Koletzko, ML Mearin, FF Kirchberg
    PLoS ONE, 2018-06-01;13(6):e0197713.
    Species: Human
    Sample Types: Milk
  74. Development of Versatile Human In Vitro Vascularized Adipose Tissue Model with Serum-Free Angiogenesis and Natural Adipogenesis Induction
    Authors: O Huttala, M Palmroth, P Hemminki, T Toimela, T Heinonen, T Ylikomi, JR Sarkanen
    Basic Clin. Pharmacol. Toxicol., 2018-04-27;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  75. Association between UCP polymorphisms and adipokines with obesity in Mexican adolescents
    Authors: R Sámano, C Huesca-Góm, R López-Maru, AK Hernández-, A Rodríguez-, M Tolentino, RM Morales, R Gamboa
    J. Pediatr. Endocrinol. Metab., 2018-04-25;0(0):.
    Species: Human
    Sample Types: Serum
  76. Follicular fluid levels of anti-M�llerian hormone, insulin-like growth factor 1 and leptin in women with fertility disorders
    Authors: R Kucera, V Babuska, Z Ulcova-Gal, V Kulda, O Topolcan
    Syst Biol Reprod Med, 2018-03-29;0(0):1-4.
    Species: Human
    Sample Types: Follicular Fluid
  77. Plasma leptin, but not resistin, TNF-? and adiponectin, is associated with echocardiographic parameters of cardiac remodeling in patients with coronary artery disease
    Authors: AD Farca?, A Rusu, MA Stoia, LA Vida-Simit
    Cytokine, 2018-01-08;103(0):46-49.
    Species: Human
    Sample Types: Plasma
  78. Interleukin-6 and leptin levels are associated with preoperative pain severity in patients with osteoarthritis but not with acute pain after total knee arthroplasty
    Authors: S Azim, J Nicholson, MJ Rebecchi, W Galbavy, T Feng, S Rizwan, RA Reinsel, M Kaczocha, H Benveniste
    Knee, 2018-01-08;0(0):.
    Species: Human
    Sample Types: Serum
  79. C-Reactive protein in relation to fecundability and anovulation among eumenorrheic women
    Authors: RG Radin, LA Sjaarda, RM Silver, CJ Nobles, SL Mumford, NJ Perkins, BD Wilcox, AZ Pollack, KC Schliep, TC Plowden, EF Schisterma
    Fertil. Steril., 2018-01-06;0(0):.
    Species: Human
    Sample Types: Serum
  80. Key Clinical Factors Predicting Adipokine and Oxidative Stress Marker Concentrations among Normal, Overweight and Obese Pregnant Women Using Artificial Neural Networks
    Authors: M Solis-Pare, G Estrada-Gu, O Perichart-, A Montoya-Es, M Guzmán-Hue, H Borboa-Oli, E Bravo-Flor, A Cardona-Pé, V Zaga-Clave, E Garcia-Lat, G Gonzalez-P, JA Hernández-, C Irles
    Int J Mol Sci, 2017-12-28;19(1):.
    Species: Human
    Sample Types: Serum
  81. Is There Any Relationship between Plasma 25-Hydroxyvitamin D?, Adipokine Profiles and Excessive Body Weight in Type 2 Diabetic Patients?
    Authors: J Kocot, P Dziemidok, M Kie?czykow, J Kurzepa, G Szcze?niak, I Musik
    Int J Environ Res Public Health, 2017-12-23;15(1):.
    Species: Human
    Sample Types: Plasma
  82. Myostatin and adipokines: The role of the metabolically unhealthy obese phenotype in muscle function and aerobic capacity in young adults
    Authors: LP Carvalho, RP Basso-Vane, L Di Thommaz, RG Mendes, MC Oliveira-J, RP Vieira, JC Bonjorno-J, CR Oliveira, R Luporini, A Borghi-Sil
    Cytokine, 2017-12-13;0(0):.
    Species: Human
    Sample Types: Plasma
  83. Plasma irisin is elevated in type 2 diabetes and is associated with increased E-selectin levels
    Authors: KS Rana, C Pararasa, I Afzal, DA Nagel, EJ Hill, CJ Bailey, HR Griffiths, I Kyrou, HS Randeva, S Bellary, JE Brown
    Cardiovasc Diabetol, 2017-11-09;16(1):147.
    Species: Human
    Sample Types: Plasma
  84. Endurance exercise training decreased serum levels of surfactant protein D and improved aerobic fitness of obese women with type-2 diabetes
    Authors: S Rezaei, MM Shamsi, M Mahdavi, A Jamali, J Prestes, RA Tibana, JW Navalta, FA Voltarelli
    Diabetol Metab Syndr, 2017-09-25;9(0):74.
    Species: Human
    Sample Types: Serum
  85. Serum levels of adiponectin and leptin as biomarkers of proteinuria in lupus nephritis
    Authors: V Diaz-Rizo, D Bonilla-La, L Gonzalez-L, D Sanchez-Mo, NS Fajardo-Ro, EE Perez-Guer, NA Rodriguez-, AM Saldaña-Cr, ML Vazquez-Vi, E Gomez-Bañu, M Vazquez-De, EG Cardona-Mu, D Cardona-Mu, X Trujillo, M Huerta, M Salazar-Pa, JI Gamez-Nava
    PLoS ONE, 2017-09-12;12(9):e0184056.
    Species: Human
    Sample Types: Serum
  86. Inkjet-printed point-of-care immunoassay on a nanoscale polymer brush enables subpicomolar detection of analytes in blood
    Authors: DY Joh, AM Hucknall, Q Wei, KA Mason, ML Lund, CM Fontes, RT Hill, R Blair, Z Zimmers, RK Achar, D Tseng, R Gordan, M Freemark, A Ozcan, A Chilkoti
    Proc. Natl. Acad. Sci. U.S.A., 2017-08-07;0(0):.
    Species: Human
    Sample Types: Serum
  87. Adipokines, C-reactive protein and Amyotrophic Lateral Sclerosis - results from a population- based ALS registry in Germany
    Authors: G Nagel, RS Peter, A Rosenbohm, W Koenig, L Dupuis, D Rothenbach, AC Ludolph
    Sci Rep, 2017-06-29;7(1):4374.
    Species: Human
    Sample Types: Serum
  88. Concurrent Aerobic and Resistance Training Has Anti-Inflammatory Effects and Increases Both Plasma and Leukocyte Levels of IGF-1 in Late Middle-Aged Type 2 Diabetic Patients
    Authors: G Annibalini, F Lucertini, D Agostini, L Vallorani, A Gioacchini, E Barbieri, M Guescini, L Casadei, A Passalia, M Del Sal, G Piccoli, M Andreani, A Federici, V Stocchi
    Oxid Med Cell Longev, 2017-06-21;2017(0):3937842.
    Species: Human
    Sample Types: Plasma
  89. Carbohydrates from Sources with a Higher Glycemic Index during Adolescence: Is Evening Rather than Morning Intake Relevant for Risk Markers of Type 2 Diabetes in Young Adulthood?
    Authors: T Diederichs, C Herder, S Ro beta bach, M Roden, SA Wudy, U Nöthlings, U Alexy, AE Buyken
    Nutrients, 2017-06-10;9(6):.
    Species: Human
    Sample Types: Serum
  90. Reproductive hormones and metabolic syndrome in 24 testicular cancer survivors and their biological brothers
    Authors: M Bandak, N Jørgensen, A Juul, J Lauritsen, MGG Kier, MS Mortensen, PS Oturai, J Mortensen, P Hojman, JW Helge, G Daugaard
    Andrology, 2017-06-09;0(0):.
    Species: Human
    Sample Types: Serum
  91. Type II Endometrial Cancer Overexpresses NILCO: A Preliminary Evaluation
    Authors: D Daley-Brow, G Oprea-Iles, KT Vann, V Lanier, R Lee, PV Candelaria, A Quarshie, R Pattillo, RR Gonzalez-P
    Dis. Markers, 2017-06-04;2017(0):8248175.
    Species: Human
    Sample Types: Tissue Homogenates
  92. Class II obese and healthy pregnant controls exhibit indistinguishable pro- and anti-inflammatory immune responses to Caesarian section
    Authors: C Graham, M Thorleifso, WP Stefura, DJ Funk, KT HayGlass
    Immun Inflamm Dis, 2017-05-25;0(0):.
    Species: Human
    Sample Types: Plasma
  93. Serum levels of leptin and adiponectin and clinical parameters in women with fibromyalgia and overweight/obesity
    Authors: ES Paiva, A Andretta, ED Batista, MM Lobo, RC Miranda, R Nisihara, ME Schieferde, CL Boguszewsk
    Arch Endocrinol Metab, 2017-02-13;0(0):0.
    Species: Human
    Sample Types: Serum
  94. Effects of exercise training on circulating levels of Dickkpof-1 and secreted frizzled-related protein-1 in breast cancer survivors: A pilot single-blind randomized controlled trial
    Authors: TH Kim, JS Chang, KS Park, J Park, N Kim, JI Lee, ID Kong
    PLoS ONE, 2017-02-08;12(2):e0171771.
    Species: Human
    Sample Types: Serum
  95. Impact of physical activity level and dietary fat content on passive overconsumption of energy in non-obese adults
    Authors: K Beaulieu, M Hopkins, J Blundell, G Finlayson
    Int J Behav Nutr Phys Act, 2017-02-06;14(1):14.
    Species: Human
    Sample Types: Plasma
  96. Type 3 Deiodinase Role on Central Thyroid Hormone Action Affects the Leptin-Melanocortin System and Circadian Activity
    Authors: Zhaofei Wu
    Endocrinology, 2017-02-01;0(0):en20161680.
    Species: Human
    Sample Types: Serum
  97. Relationships of insulin-like growth factor-1, its binding proteins, and cardiometabolic risk in hypertensive perimenopausal women
    Authors: A Olszanecka, A Dragan, K Kawecka-Ja, D Fedak, D Czarnecka
    Metab. Clin. Exp., 2017-01-12;69(0):96-106.
    Species: Human
    Sample Types: Plasma
  98. The effect of BMI, serum leptin, and adiponectin levels on prognosis in patients with non-ischaemic dilated cardiomyopathy
    Authors: C Wojciechow, W Jache?, E Romuk, E Nowalany-K, A Tomasik, L Siemi?ska
    Endokrynol Pol, 2017-01-01;68(1):26-34.
    Species: Human
    Sample Types: Serum
  99. Metabolic Syndrome and Selective Inflammatory Markers in Psoriatic Patients
    Authors: S Vachatova, C Andrys, J Krejsek, M Salavec, K Ettler, V Rehacek, E Cermakova, A Malkova, Z Fiala, L Borska
    J Immunol Res, 2016-12-21;2016(0):5380792.
    Species: Human
    Sample Types: Serum
  100. Dietary patterns and cardiometabolic and endocrine plasma biomarkers in US women
    Authors: Hala B AlEssa
    Am. J. Clin. Nutr, 2016-12-14;0(0):.
    Species: Human
    Sample Types: Plasma
  101. Leptin, Leptin Soluble Receptor, and the Free Leptin Index following a Diet and Physical Activity Lifestyle Intervention in Obese Males and Females
    Authors: Jeffrey E Herrick
    J Obes, 2016-12-06;2016(0):8375828.
    Species: Human
    Sample Types: Serum
  102. Altered Systemic Adipokines in Patients with Chronic Urticaria
    Authors: Hoang Kim Tu Trinh
    Int. Arch. Allergy Immunol, 2016-12-01;171(2):102-110.
    Species: Human
    Sample Types: Serum
  103. Effects of different degrees of insulin resistance on endothelial function in�obese�adults undergoing alternate day�fasting
    Authors: Kristin K Hoddy
    Nutr Healthy Aging, 2016-10-27;4(1):63-71.
    Species: Human
    Sample Types: Plasma
  104. Ghrelin and hormonal markers under exercise training in patients with heart failure with preserved ejection fraction: results from the Ex-DHF pilot study
    Authors: TD Trippel, V Holzendorf, M Halle, G Gelbrich, K Nolte, A Duvinage, S Schwarz, T Rutscher, J Wiora, R Wachter, C Herrmann-L, HD Duengen, G Hasenfu beta, B Pieske, F Edelmann
    ESC Heart Fail, 2016-08-31;4(1):56-65.
    Species: Human
    Sample Types: Serum
  105. Maternal obesity drives functional alterations in uterine NK cells
    JCI Insight, 2016-07-21;1(11):e85560.
    Species: Human
    Sample Types: Serum
  106. A Dietary Supplement Containing Cinnamon, Chromium and Carnosine Decreases Fasting Plasma Glucose and Increases Lean Mass in Overweight or Obese Pre-Diabetic Subjects: A Randomized, Placebo-Controlled Trial.
    Authors: Liu Y, Cotillard A, Vatier C, Bastard J, Fellahi S, Stevant M, Allatif O, Langlois C, Bieuvelet S, Brochot A, Guilbot A, Clement K, Rizkalla S
    PLoS ONE, 2015-09-25;10(9):e0138646.
    Species: Human
    Sample Types: Plasma
  107. Circulating adipokines and insulin resistance in subjects with combined cardiac and metabolic syndrome X.
    Authors: Liang K, Lee W, Lee W, Liao Y, Wang K, Lee I, Wang J, Sheu W
    Diabetol Metab Syndr, 2015-09-24;7(0):83.
    Species: Human
    Sample Types: Serum
  108. Lower Circulating C1q/TNF-Related Protein-3 (CTRP3) Levels Are Associated with Obesity: A Cross-Sectional Study.
    Authors: Wolf R, Steele K, Peterson L, Magnuson T, Schweitzer M, Wong G
    PLoS ONE, 2015-07-29;10(7):e0133955.
    Species: Human
    Sample Types: Serum
  109. Inflammation-regulating factors in ascites as predictive biomarkers of drug resistance and progression-free survival in serous epithelial ovarian cancers.
    Authors: Lane D, Matte I, Garde-Granger P, Laplante C, Carignan A, Rancourt C, Piche A
    BMC Cancer, 2015-07-01;15(0):492.
    Species: Human
    Sample Types: Peritoneal Fluid
  110. Cord blood adipokines, neonatal anthropometrics and postnatal growth in offspring of Hispanic and Native American women with diabetes mellitus.
    Authors: Teague A, Fields D, Aston C, Short K, Lyons T, Chernausek S
    Reprod Biol Endocrinol, 2015-06-26;13(0):68.
    Species: Human
    Sample Types: Serum
  111. Additive regulation of adiponectin expression by the mediterranean diet olive oil components oleic Acid and hydroxytyrosol in human adipocytes.
    Authors: Scoditti E, Massaro M, Carluccio M, Pellegrino M, Wabitsch M, Calabriso N, Storelli C, De Caterina R
    PLoS ONE, 2015-06-01;10(6):e0128218.
    Species: Human
    Sample Types: Cell Culture Supernates
  112. Leptin levels are negatively correlated with 2-arachidonoylglycerol in the cerebrospinal fluid of patients with osteoarthritis.
    Authors: Nicholson J, Azim S, Rebecchi M, Galbavy W, Feng T, Reinsel R, Rizwan S, Fowler C, Benveniste H, Kaczocha M
    PLoS ONE, 2015-04-02;10(4):e0123132.
    Species: Human
    Sample Types: Serum
  113. A cross-over experiment to investigate possible mechanisms for lower BMIs in people who habitually eat breakfast.
    Authors: Reeves S, Huber J, Halsey L, Villegas-Montes M, Elgumati J, Smith T
    Eur J Clin Nutr, 2015-01-07;69(5):632-7.
    Species: Human
    Sample Types: Serum
  114. Short-term intake of a Japanese-style healthy lunch menu contributes to prevention and/or improvement in metabolic syndrome among middle-aged men: a non-randomized controlled trial.
    Authors: Inoue H, Sasaki R, Aiso I, Kuwano T
    Lipids Health Dis, 2014-03-27;13(0):57.
    Species: Human
    Sample Types: Serum
  115. Regional adipose tissue hormone/cytokine production before and after weight loss in abdominally obese women.
    Authors: You T, Wang X, Murphy K, Lyles M, Demons J, Yang R, Gong D, Nicklas B
    Obesity (Silver Spring), 2014-03-25;22(7):1679-84.
    Species: Human
    Sample Types: Plasma
  116. Serum levels of apoptosis inhibitor of macrophage are associated with hepatic fibrosis in patients with chronic hepatitis C.
    Authors: Mera K, Uto H, Mawatari S, Ido A, Yoshimine Y, Nosaki T, Oda K, Tabu K, Kumagai K, Tamai T, Moriuchi A, Oketani M, Shimada Y, Hidaka M, Eguchi S, Tsubouchi H
    BMC Gastroenterol, 2014-02-13;14(0):27.
    Species: Human
    Sample Types: Serum
  117. Leptin is associated with vascular endothelial function in overweight patients with type 2 diabetes.
    Authors: Morioka T, Emoto M, Yamazaki Y, Kawano N, Imamura S, Numaguchi R, Urata H, Motoyama K, Mori K, Fukumoto S, Koyama H, Shoji T, Inaba M
    Cardiovasc Diabetol, 2014-01-10;13(0):10.
    Species: Human
    Sample Types: Plasma
  118. Adiponectin is a candidate biomarker of lower extremity bone density in men with chronic spinal cord injury.
    Authors: Doherty A, Battaglino R, Donovan J, Gagnon D, Lazzari A, Garshick E, Zafonte R, Morse L
    J Bone Miner Res, 2014-01-01;29(1):251-9.
    Species: Human
    Sample Types: Plasma
  119. Association between traffic-related air pollution, subclinical inflammation and impaired glucose metabolism: results from the SALIA study.
    Authors: Teichert T, Vossoughi M, Vierkotter A, Sugiri D, Schikowski T, Schulte T, Roden M, Luckhaus C, Herder C, Kramer U
    PLoS ONE, 2013-12-10;8(12):e83042.
    Species: Human
    Sample Types: Plasma
  120. Brain-derived neurotrophic factor in human subjects with function-altering melanocortin-4 receptor variants.
    Authors: Hohenadel M, Thearle M, Grice B, Huang H, Dai M, Tao Y, Hunter L, Palaguachi G, Mou Z, Kim R, Tsang M, Haack K, Voruganti V, Cole S, Butte N, Comuzzie A, Muller Y, Baier L, Krakoff J, Knowler W, Yanovski J, Han J
    Int J Obes (Lond), 2013-11-26;38(8):1068-74.
    Species: Human
    Sample Types: Serum
  121. A prospective study of circulating adipokine levels and risk of multiple myeloma.
    Authors: Hofmann J, Liao L, Pollak M, Wang Y, Pfeiffer R, Baris D, Andreotti G, Lan Q, Landgren O, Rothman N, Purdue M
    Blood, 2012-09-24;120(22):4418-20.
    Species: Human
    Sample Types: Plasma
  122. Alterations of leptin in the course of inflammation and severe sepsis.
    BMC Infect Dis, 2012-09-14;12(0):217.
    Species: Human
    Sample Types: Serum
  123. The type and quantity of dietary fat and carbohydrate alter faecal microbiome and short-chain fatty acid excretion in a metabolic syndrome 'at-risk' population.
    Authors: Fava, F, Gitau, R, Griffin, B A, Gibson, G R, Tuohy, K M, Lovegrove, J A
    Int J Obes (Lond), 2012-03-13;37(2):216-23.
    Species: Human
    Sample Types: Plasma
  124. Adipocytokines and CD34 progenitor cells in Alzheimer's disease.
    Authors: Bigalke B, Schreitmuller B, Sopova K, Paul A, Stransky E, Gawaz M, Stellos K, Laske C
    PLoS ONE, 2011-05-25;6(5):e20286.
    Species: Human
    Sample Types: Plasma
  125. Effects of dietary fat modification on insulin sensitivity and on other risk factors of the metabolic syndrome-LIPGENE: a European randomized dietary intervention study.
    Authors: Tierney AC, McMonagle J, Shaw DI, Gulseth HL, Helal O, Saris WH, Paniagua JA, Golabek-Leszczynska I, Defoort C, Williams CM, Karsltrom B, Vessby B, Dembinska-Kiec A, Lopez-Miranda J, Blaak EE, Drevon CA, Gibney MJ, Lovegrove JA, Roche HM
    Int J Obes (Lond), 2010-10-12;35(6):800-9.
    Species: Human
    Sample Types: Serum
  126. Differential adaptation of human gut microbiota to bariatric surgery-induced weight loss: links with metabolic and low-grade inflammation markers.
    Authors: Furet JP, Kong LC, Tap J, Poitou C, Basdevant A, Bouillot JL, Mariat D, Corthier G, Dore J, Henegar C, Rizkalla S, Clement K
    Diabetes, 2010-09-28;59(12):3049-57.
    Species: Human
    Sample Types: Plasma
  127. Leptin exacerbates sepsis-mediated morbidity and mortality.
    Authors: Shapiro NI, Khankin EV, van Meurs M
    J. Immunol., 2010-06-02;185(1):517-24.
    Species: Human
    Sample Types: Plasma
  128. Exenatide affects circulating cardiovascular risk biomarkers independently of changes in body composition.
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    Diabetes Care, 2010-04-27;33(8):1734-7.
    Species: Human
    Sample Types: Serum
  129. Improvements in coronary heart disease risk indicators by alternate-day fasting involve adipose tissue modulations.
    Authors: Bhutani S, Klempel MC, Berger RA, Varady KA
    Obesity (Silver Spring), 2010-03-18;18(11):2152-9.
    Species: Human
    Sample Types: Plasma
  130. Environmental tobacco smoke and cardiometabolic risk in young children: results from a survey in south-west Germany.
    Authors: Nagel G, Arnold FJ, Wilhelm M, Link B, Zoellner I, Koenig W
    Eur. Heart J., 2009-05-24;30(15):1885-93.
    Species: Human
    Sample Types: Plasma
  131. HIV increases markers of cardiovascular risk: results from a randomized, treatment interruption trial.
    Authors: Calmy A, Gayet-Ageron A, Montecucco F, Nguyen A, Mach F, Burger F, Ubolyam S, Carr A, Ruxungtham K, Hirschel B, Ananworanich J
    AIDS, 2009-05-15;23(8):929-39.
    Species: Human
    Sample Types: Plasma
  132. Absence of leptin resistance in platelets from morbidly obese individuals may contribute to the increased thrombosis risk in obesity.
    Authors: Dellas C, Schafer K, Rohm I, Lankeit M, Ellrott T, Faustin V, Riggert J, Hasenfuss G, Konstantinides S
    Thromb. Haemost., 2008-12-01;100(6):1123-9.
    Species: Human
    Sample Types: Plasma
  133. Positive energy balance is associated with accelerated muscle atrophy and increased erythrocyte glutathione turnover during 5 wk of bed rest.
    Authors: Biolo G, Agostini F, Simunic B, Sturma M, Torelli L, Preiser JC, Deby-Dupont G, Magni P, Strollo F, di Prampero P, Guarnieri G, Mekjavic IB, Pisot R, Narici MV
    Am. J. Clin. Nutr., 2008-10-01;88(4):950-8.
    Species: Human
    Sample Types: Plasma
  134. Diurnal variation of human sweet taste recognition thresholds is correlated with plasma leptin levels.
    Authors: Nakamura Y, Sanematsu K, Ohta R, Shirosaki S, Koyano K, Nonaka K, Shigemura N, Ninomiya Y
    Diabetes, 2008-07-15;57(10):2661-5.
    Species: Human
    Sample Types: Plasma
  135. Gene expression profiling of human skeletal muscle in response to stabilized weight loss.
    Authors: Larrouy D, Barbe P, Valle C, Dejean S, Pelloux V, Thalamas C, Bastard JP, Le Bouil A, Diquet B, Clement K, Langin D, Viguerie N
    Am. J. Clin. Nutr., 2008-07-01;88(1):125-32.
    Species: Human
    Sample Types: Plasma
  136. Retinol-binding protein 4 and lipocalin-2 in childhood and adolescent obesity: when children are not just "small adults".
    Authors: Kanaka-Gantenbein C, Margeli A, Pervanidou P, Sakka S, Mastorakos G, Chrousos GP, Papassotiriou I
    Clin. Chem., 2008-05-16;54(7):1176-82.
    Species: Human
    Sample Types: Serum
  137. The levels of steroid hormones and cytokines in individual follicles are not associated with the fertilization outcome after intracytoplasmic sperm injection.
    Authors: Asimakopoulos B, Abu-Hassan D, Metzen E, Al-Hasani S, Diedrich K, Nikolettos N
    Fertil. Steril., 2007-11-05;90(1):60-4.
    Species: Human
    Sample Types: Follicular Fluid
  138. Obesity, adipokines, and abdominal aortic aneurysm: Health in Men study.
    Authors: Golledge J, Clancy P, Jamrozik K, Norman PE
    Circulation, 2007-10-29;116(20):2275-9.
    Species: Human
    Sample Types: Serum
  139. Nitrosative stress predicts the presence and severity of nonalcoholic fatty liver at different stages of the development of insulin resistance and metabolic syndrome: possible role of vitamin A intake.
    Authors: Musso G, Gambino R, De Michieli F, Biroli G, Premoli A, Pagano G, Bo S, Durazzo M, Cassader M
    Am. J. Clin. Nutr., 2007-09-01;86(3):661-71.
    Species: Human
    Sample Types: Serum
  140. The association of gastric leptin with oesophageal inflammation and metaplasia.
    Authors: Francois F, Roper J, Goodman AJ, Pei Z, Ghumman M, Mourad M, de Perez AZ, Perez-Perez GI, Tseng CH, Blaser MJ
    Gut, 2007-08-30;57(1):16-24.
    Species: Human
    Sample Types: Serum
  141. Panel of markers can accurately predict endometriosis in a subset of patients.
    Authors: Seeber B, Sammel MD, Fan X, Gerton GL, Shaunik A, Chittams J, Barnhart KT
    Fertil. Steril., 2007-08-13;89(5):1073-81.
    Species: Human
    Sample Types: Serum
  142. Muscle-specific knockout of PKC-lambda impairs glucose transport and induces metabolic and diabetic syndromes.
    Authors: Farese RV, Sajan MP, Yang H, Li P, Mastorides S, Gower WR, Nimal S, Choi CS, Kim S, Shulman GI, Kahn CR, Braun U, Leitges M
    J. Clin. Invest., 2007-08-01;117(8):2289-301.
    Species: Human
    Sample Types: Serum
  143. Adiponectin and leptin in maternal serum, cord blood, and breast milk.
    Authors: Weyermann M, Beermann C, Brenner H, Rothenbacher D
    Clin. Chem., 2006-09-21;52(11):2095-102.
    Species: Human
    Sample Types: Serum
  144. Plasma agouti-related protein levels in women with anorexia nervosa.
    Authors: Moriya J, Takimoto Y, Yoshiuchi K
    Psychoneuroendocrinology, 2006-08-14;31(9):1057-61.
    Species: Human
    Sample Types: Plasma
  145. Altered hepatic expression of SREBP-1 and PPARgamma is associated with liver injury in insulin-resistant lipodystrophic HIV-infected patients.
    Authors: Lemoine M, Barbu V, Girard PM, Kim M, Bastard JP, Wendum D, Paye F, Housset C, Capeau J, Serfaty L
    AIDS, 2006-02-14;20(3):387-95.
    Species: Human
    Sample Types: Serum
  146. Genetic regulation of the variation of circulating insulin-like growth factors and leptin in human pedigrees.
    Authors: Pantsulaia Ia, Pantsulaia I, Trofimov S, Kobyliansky E, Livshits G
    Metab. Clin. Exp., 2005-07-01;54(7):975-81.
    Species: Human
    Sample Types: Plasma
  147. Adiponectin and other adipocytokines as predictors of markers of triglyceride-rich lipoprotein metabolism.
    Authors: Chan DC, Watts GF, Ng TW, Uchida Y, Sakai N, Yamashita S, Barrett PH
    Clin. Chem., 2005-01-13;51(3):578-85.
    Species: Human
    Sample Types: Plasma
  148. Enhanced monocyte chemoattractant protein-3/CC chemokine ligand-7 in usual interstitial pneumonia.
    Authors: Choi ES, Jakubzick C, Carpenter KJ, Kunkel SL, Evanoff H, Martinez FJ, Flaherty KR, Toews GB, Colby TV, Kazerooni EA, Gross BH, Travis WD, Hogaboam CM
    Am. J. Respir. Crit. Care Med., 2004-06-10;170(5):508-15.
    Species: Human
    Sample Types: Cell Culture Supernates
  149. Determinants of plasma leptin concentration in postmenopausal women.
    Authors: Brooks-Asplund EM, Tupper CE, Daun JM, Kenney WL, Cannon JG
    Mech. Ageing Dev., 2004-02-01;125(2):117-9.
    Species: Human
    Sample Types:

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Reviews for Human Leptin Quantikine ELISA Kit

Average Rating: 4.9 (Based on 9 Reviews)

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Human Leptin Quantikine ELISA Kit
By Anonymous on 11/14/2022
Sample Tested: Serum

Human Leptin Quantikine ELISA Kit
By Anonymous on 05/25/2022
Sample Tested: EDTA Plasma

Human Leptin Quantikine ELISA Kit
By Anonymous on 05/20/2022
Sample Tested: EDTA Plasma,Serum

Human Leptin Quantikine ELISA Kit
By Anonymous on 01/31/2022
Sample Tested: Serum

Human Leptin Quantikine ELISA Kit
By Anonymous on 01/14/2022
Sample Tested: Serum

Human Leptin Quantikine ELISA Kit
By Anonymous on 01/27/2021
Sample Tested: Serum

Human Leptin Quantikine ELISA Kit
By Anonymous on 01/25/2021
Sample Tested: Serum

Per usual, R&D kit was easy to use and straight forward. Produced great results.


Human Leptin Quantikine ELISA Kit
By Kimberly Steen on 01/22/2021
Sample Tested: EDTA Plasma

Product preformed well- instructions were clear, included detailed background, and the reagent was easy to prepare.


Human Leptin Quantikine ELISA Kit
By Anonymous on 05/15/2017
Sample Tested: Human serum