Human TNF RII/TNFRSF1B PE-conjugated Antibody Summary
Extracellular domain
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
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Detection of TNF RII/TNFRSF1B in Human Granulocytes by Flow Cytometry. Human peripheral blood granulocytes were stained with Mouse Anti-Human TNF RII/TNFRSF1B PE-conjugated Monoclonal Antibody (Catalog # FAB226P, filled histogram) or isotype control antibody (Catalog # IC003P, open histogram). View our protocol for Staining Membrane-associated Proteins.
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Preparation and Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: TNF RII/TNFRSF1B
TNF RII is a type I transmembrane glycoprotein primarily expressed on hematopoietic cells and is designated TNFRSF1B. TNF RII is a high-affinity receptor for TNF‑ alpha and TNF-beta. A soluble form of the receptor generated by proteolytic cleavage functions as a TNF antagonist.
Product Datasheets
Citations for Human TNF RII/TNFRSF1B PE-conjugated Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
12
Citations: Showing 1 - 10
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Co-expression of TNF receptors 1 and 2 on melanomas facilitates soluble TNF-induced resistance to MAPK pathway inhibitors
Authors: CA Sander, EA Rush, J Shi, LMRB Arantes, RJ Tesi, MA Ross, MJ Calderon, SC Watkins, JM Kirkwood, RL Ferris, LH Butterfiel, L Vujanovic
Journal of Translational Medicine, 2022-07-25;20(1):331.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
TNFR2 ligation in human T regulatory cells enhances IL2-induced cell proliferation through the non-canonical NF-?B pathway
Authors: J Wang, R Ferreira, W Lu, S Farrow, K Downes, L Jermutus, R Minter, RS Al-Lamki, JS Pober, JR Bradley
Sci Rep, 2018-08-13;8(1):12079.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Memory Regulatory T cells Increase Only In Inflammatory Phase of Chronic Hepatitis B Infection and Related to Galectin-9/Tim-3 interaction
Authors: CC Hu, WJ Jeng, YC Chen, JH Fang, CH Huang, W Teng, YC Hsieh, YC Lin, RN Chien, IS Sheen, CY Lin
Sci Rep, 2017-11-10;7(1):15280.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
TNFR2 increases the sensitivity of ligand-induced activation of the p38 MAPK and NF-kappaB pathways and signals TRAF2 protein degradation in macrophages.
Authors: Ruspi G, Schmidt E, McCann F, Feldmann M, Williams R, Stoop A, Dean J
Cell Signal, 2013-12-27;26(4):683-90.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Suppression of TNF-alpha and IL-1 signaling identifies a mechanism of homeostatic regulation of macrophages by IL-27.
Authors: Kalliolias GD, Gordon RA, Ivashkiv LB
J. Immunol., 2010-10-22;185(11):7047-56.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Genome-wide comparison between IL-17A- and IL-17F-induced effects in human rheumatoid arthritis synoviocytes.
Authors: Zrioual S, Ecochard R, Tournadre A, Lenief V, Cazalis MA, Miossec P
J. Immunol., 2009-03-01;182(0):3112-20.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of Th1 and Th2 chemokines by human eosinophils: evidence for a critical role of TNF-alpha.
Authors: Liu LY, Bates ME, Jarjour NN, Busse WW, Bertics PJ, Kelly EA
J. Immunol., 2007-10-01;179(7):4840-8.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Interaction between transmembrane TNF and TNFR1/2 mediates the activation of monocytes by contact with T cells.
Authors: Rossol M, Meusch U, Pierer M, Kaltenhauser S, Hantzschel H, Hauschildt S, Wagner U
J. Immunol., 2007-09-15;179(6):4239-48.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Phagocytosis of codeveloping megakaryocytic progenitors by dendritic cells in culture with thrombopoietin and tumor necrosis factor-alpha and its possible role in hemophagocytic syndrome.
Authors: Saito K, Hirokawa M, Inaba K, Fukaya H, Kawabata Y, Komatsuda A, Yamashita J, Sawada K
Blood, 2005-10-18;107(4):1366-74.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Codevelopment of dendritic cells along with erythroid differentiation from human CD34(+) cells by tumor necrosis factor-alpha.
Authors: Fukaya H, Xiao W, Inaba K, Suzuki Y, Hirokawa M, Kawabata Y, Komatsuda A, Endo T, Kishimoto H, Takada G, Sawada K
Exp. Hematol., 2004-05-01;32(5):450-60.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Tumor necrosis factor-alpha inhibits generation of glycophorin A+ cells by CD34+ cells.
Authors: Xiao W, Koizumi K, Nishio M, Endo T, Osawa M, Fujimoto K, Sato I, Sakai T, Koike T, Sawada K
Exp. Hematol., 2002-11-01;30(11):1238-47.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Inhibition of programmed cell death impairs in vitro vascular-like structure formation and reduces in vivo angiogenesis.
Authors: Segura I, 2019, Serrano A, De Buitrago GG, Gonzalez MA, Abad JL, Claveria C, Gomez L, Bernad A, Martinez-A C, Riese HH
7096, 2002-06-01;16(8):833-41.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry
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