IL-5 Antibody [Janelia Fluor® 525]

Name: IL-5 Antibody [Janelia Fluor® 525]
Brand: Novus Biologicals
SKU: AF545JF525
Price: 549 USD
Availability: InStock

Novus Biologicals | Catalog # AF545JF525

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Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Rat

Applications

Western Blot, Neutralization, Immunocytochemistry

Label

Janelia Fluor 525

Antibody Source

Polyclonal Goat IgG

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Product Specifications

Immunogen

S. frugiperda insect ovarian cell line Sf 21-derived recombinant rat IL-5
Met20-Val132
Accession # Q08125

Specificity

Detects rat IL‑5 in direct ELISAs and Western blots. In direct ELISAs, approximately 50% cross-reactivity with recombinant mouse IL‑5 is observed and 5% cross‑reactivity with recombinant human IL‑5 is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for IL-5 Antibody [Janelia Fluor® 525]

Application

Recommended Usage

Immunocytochemistry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Neutralization

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: IL-5

IL-5 (T cell replacing factor (TRF), eosinophil differentiation factor (EDF)) is a hematopoietic growth factor that stimulates the proliferation, differentiation and activation of eosinophils. It is produced by mast cells, T cells and eosinophils and has an important role in activating cell-mediated immunity following parasitic infections. It belongs to the same cytokine family as IL-3 and GM-CSF. The biologically active IL-5 consists of an antiparallel homodimer linked by disulfide bonds. Human and murine IL-5 are 70% identical at the amino acid level and show species cross-reactivity. IL-5 exerts its effects on target cells by binding to specific cell surface receptors.

Long Name

Interleukin 5

Alternate Names

BCDF mu, BCGFII, EDF, Eo-CSF, IL5, TRF

Gene Symbol

IL5

Additional IL-5 Products

Product Documents for IL-5 Antibody [Janelia Fluor® 525]

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Product Specific Notices for IL-5 Antibody [Janelia Fluor® 525]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.