Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit

  (204 citations)
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Citations (204)
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  • Assay Length
    4.5 hours
  • Sample Type & Volume Required Per Well
    Cell Culture Supernates (50 uL), Cell Lysates (50 uL), Serum (50 uL), EDTA Plasma (50 uL), Heparin Plasma (50 uL)
  • Sensitivity
    4.8 pg/mL
  • Assay Range
    12.5 - 800 pg/mL (Cell Culture Supernates, Cell Lysates, Serum, EDTA Plasma, Heparin Plasma)
  • Specificity
    Natural and recombinant mouse IL-1 beta
  • Cross-reactivity
    < 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
  • Interference
    No significant interference observed with available related molecules.
Product Summary
The Quantikine Mouse IL-1 beta Immunoassay is a 4.5 hour solid phase ELISA designed to measure mouse IL-1 beta in cell culture supernates, cell lysates, serum, and plasma. It contains E. coli-expressed recombinant mouse IL-1 beta and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate the recombinant factor accurately. Results obtained using natural mouse IL-1 beta showed dose-response curves that were parallel to the standard curves obtained using the recombinant kit standards. These results indicate that this kit can be used to determine relative mass values for natural mouse IL-1 beta.

Precision
Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision
Cell Culture Supernates, Cell Lysates, Serum, EDTA Plasma, Heparin Plasma
Intra-Assay Precision Inter-Assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 40 40 40
Mean 33.5 92.9 386 34.6 93.5 423
Standard Deviation 2.5 4.3 11.7 2.9 6.2 23.9
CV% 7.5 4.6 3 8.4 6.6 5.7

Recovery

The recovery of mouse IL-1 beta spiked to three levels throughout the range of the assay in various matrices was evaluated.

Sample Type Average % Recovery Range %
Cell Culture Supernates (n=4) 106 95-119
Cell Lysates (n=4) 115 110-120
EDTA Plasma (n=4) 108 101-117
Heparin Plasma (n=4) 97 87-114
Serum (n=4) 105 98-113
Linearity
To assess the linearity of the assay, samples containing and/or spiked with high concentrations of mouse IL-1 beta were serially diluted with Calibrator Diluent to produce samples with values within the dynamic range of the assay.
 IL-1 beta/IL-1F2 [HRP]
Product Datasheets

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Preparation and Storage
  • Storage
    Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Background: IL-1 beta/IL-1F2
IL-1 beta (Interleukin-1 beta) is produced in response to inflammatory agents, infections, or microbial endotoxins. It plays a central role in immune and inflammatory responses, bone remodeling, fever, carbohydrate metabolism, and GH/IGF-I physiology. IL-1 beta dysregulation is implicated in many pathological conditions including sepsis, rheumatoid arthritis, inflammatory bowel disease, acute and chronic myelogenous leukemia, insulin-dependent diabetes mellitus, atherosclerosis, neuronal injury, and aging-related diseases. Intracellular cleavage of the IL-1 beta precursor by Caspase-1/ICE is a key step in the inflammatory response. IL-1 beta binds to IL-1 RI and IL-1 RII. The IL-1 receptor accessory protein (IL-1 RAcP) associates with IL-1 RI and is required for IL-1 RI signal transduction, and IL-1ra is a secreted molecule that functions as a competitive inhibitor of IL-1 bioactivity.
  • Long Name:
    Interleukin 1 beta
  • Entrez Gene IDs:
    3553 (Human); 16176 (Mouse); 24494 (Rat); 397122 (Porcine); 403974 (Canine); 100034237 (Equine); 100135556 (Guinea Pig)
  • Alternate Names:
    catabolin; IL1 beta; IL-1 beta; IL-1; IL1B; IL-1b; IL1-BETA; IL-1F2; IL1F2IL-1 beta; interleukin 1, beta; interleukin-1 beta; preinterleukin 1 beta; pro-interleukin-1-beta
Related Research Areas
Citations:

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

204 Citations: Showing 1 - 10
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Species
Applications
Sample Type
  1. Macrophage-derived IL-1?/NF-?B signaling mediates parenteral nutrition-associated cholestasis
    Authors: KC El Kasmi, PM Vue, AL Anderson, MW Devereaux, S Ghosh, N Balasubram, SA Fillon, C Dahrenmoel, A Allawzi, C Woods, S McKenna, CJ Wright, L Johnson, A D'Alessand, JA Reisz, E Nozik-Gray, FJ Suchy, RJ Sokol
    Nat Commun, 2018;9(1):1393.
    Species: Mouse
    Sample Type: Serum
  2. Crude extract and fractions from Eugenia uniflora Linn leaves showed anti-inflammatory, antioxidant, and antibacterial activities
    Authors: TR Falcão, AA de Araújo, LAL Soares, RT de Moraes, ICF Bezerra, MRA Ferreira, MA de Souza N, MCN Melo, RF de Araújo, ACV de Aguiar, JS de Medeiro, GCB Guerra
    BMC Complement Altern Med, 2018;18(1):84.
    Species: Mouse
    Sample Type: Peritoneal Fluid
  3. CR6 interacting factor 1 deficiency promotes endothelial inflammation by SIRT1 downregulation
    Authors: S Piao, JW Lee, H Nagar, SB Jung, S Choi, S Kim, I Lee, SM Kim, N Shin, YR Lee, SD Lee, JB Park, K Irani, M Won, GM Hur, BH Jeon, DW Kim, CS Kim
    PLoS ONE, 2018;13(2):e0192693.
    Species: Mouse
    Sample Type: Plasma
  4. The NLRP3 Inflammasome May Contribute to Pathologic Neovascularization in the Advanced Stages of Diabetic Retinopathy
    Authors: SS Chaurasia, RR Lim, BH Parikh, YS Wey, BB Tun, TY Wong, CD Luu, R Agrawal, A Ghosh, A Mortellaro, E Rackoczy, RR Mohan, VA Barathi
    Sci Rep, 2018;8(1):2847.
    Species: Mouse
    Sample Type: Tissue Homogenates
  5. LncRNA GAS5 Overexpression Reverses LPS-Induced Inflammatory Injury and Apoptosis Through Up-Regulating KLF2 Expression in ATDC5 Chondrocytes
    Authors: F Li, J Sun, S Huang, G Su, G Pi
    Cell. Physiol. Biochem., 2018;45(3):1241-1251.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  6. Xanthohumol prevents dextran sulfate sodium-induced colitis via inhibition of IKK?/NF-?B signaling in mice
    Authors: JM Cho, SM Yun, YH Choi, J Heo, NJ Kim, SH Kim, EH Kim
    Oncotarget, 2018;9(1):866-880.
    Species: Mouse
    Sample Type: Serum
  7. MTOR Suppresses Environmental Particle-Induced Inflammatory Response in Macrophages
    Authors: Z Li, Y Wu, H Chen, C Zhu, L Dong, Y Wang, H Liu, X Xu, J Zhou, Y Wu, W Li, S Ying, H Shen, Z Chen
    J. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Type: BALF
  8. An unexpected link between fatty acid synthase and cholesterol synthesis in proinflammatory macrophage activation
    Authors: RG Carroll, Z Zas?ona, S Galván-Peñ, EL Koppe, DC Sévin, S Angiari, M Triantafil, K Triantafil, LK Modis, LA O'Neill
    J. Biol. Chem., 2018;293(15):5509-5521.
    Species: Mouse
    Sample Type: Serum
  9. Interleukin-1 receptor antagonist-mediated neuroprotection by umbilical cord-derived mesenchymal stromal cells following transplantation into a rodent stroke model
    Authors: SH Oh, C Choi, JE Noh, N Lee, YW Jeong, I Jeon, JM Shin, JH Kim, HJ Kim, JM Lee, HS Kim, OJ Kim, J Song
    Exp. Mol. Med., 2018;50(4):22.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  10. Interference of the T Cell and Antigen-Presenting Cell Costimulatory Pathway Using CTLA4-Ig (Abatacept) Prevents Staphylococcal Enterotoxin B Pathology
    Authors: SJ Whitfield, C Taylor, JE Risdall, GD Griffiths, JT Jones, ED Williamson, S Rijpkema, L Saraiva, S Vessillier, AC Green, AJ Carter
    J. Immunol, 2017;0(0):.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  11. NAD(+) augmentation ameliorates acute pancreatitis through regulation of inflammasome signalling
    Authors: A Shen, HJ Kim, GS Oh, SB Lee, SH Lee, A Pandit, D Khadka, SK Choe, SC Kwak, SH Yang, EY Cho, HS Kim, H Kim, R Park, TH Kwak, HS So
    Sci Rep, 2017;7(1):3006.
    Species: Mouse
    Sample Type: Serum
  12. Alleviation of secondary brain injury, posttraumatic inflammation, and brain edema formation by inhibition of factor XIIa
    Authors: S Hopp, MW Nolte, C Stetter, C Kleinschni, AL Sirén, C Albert-Wei
    J Neuroinflammation, 2017;14(1):39.
    Species: Mouse
    Sample Type: Plasma
  13. P2X7 receptor antagonism prevents IL-1? release from salivary epithelial cells and reduces inflammation in a mouse model of autoimmune exocrinopathy
    Authors: MG Khalafalla, LT Woods, JM Camden, AA Khan, KH Limesand, MJ Petris, L Erb, GA Weisman
    J. Biol. Chem., 2017;0(0):.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  14. Calf Spleen Extractive Injection protects mice against cyclophosphamide-induced hematopoietic injury through G-CSF-mediated JAK2/STAT3 signaling
    Authors: W Lu, D Jia, S An, M Mu, X Qiao, Y Liu, X Li, D Wang
    Sci Rep, 2017;7(1):8402.
    Species: Mouse
    Sample Type: Plasma
  15. Specific calpain inhibition protects kidney against inflammaging
    Authors: G Hanouna, L Mesnard, S Vandermeer, J Perez, S Placier, JP Haymann, F Campagne, J Moroch, A Bataille, L Baud, E Letavernie
    Sci Rep, 2017;7(1):8016.
    Species: Mouse
    Sample Type: Peritoneal Fluid
  16. Lentinan from shiitake selectively attenuates AIM2 and non-canonical inflammasome activation while inducing pro-inflammatory cytokine production
    Authors: H Ahn, E Jeon, JC Kim, SG Kang, SI Yoon, HJ Ko, PH Kim, GS Lee
    Sci Rep, 2017;7(1):1314.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  17. Protective Efficacy of the Trivalent Pseudomonas aeruginosa Vaccine Candidate PcrV-OprI-Hcp1 in Murine Pneumonia and Burn Models
    Authors: F Yang, J Gu, L Yang, C Gao, H Jing, Y Wang, H Zeng, Q Zou, F Lv, J Zhang
    Sci Rep, 2017;7(1):3957.
    Species: Mouse
    Sample Type: BALF
  18. STAT1 Represses Cytokine-Producing Group 2 and Group 3 Innate Lymphoid Cells during Viral Infection
    Authors: MT Stier, K Goleniewsk, JY Cephus, DC Newcomb, TP Sherrill, KL Boyd, MH Bloodworth, ML Moore, K Chen, JK Kolls, RS Peebles
    J. Immunol., 2017;0(0):.
    Species: Mouse
    Sample Type: Tissue Homogenates
  19. Cthrc1 lowers pulmonary collagen associated with bleomycin-induced fibrosis and protects lung function
    Authors: AP Binks, M Beyer, R Miller, RJ LeClair
    Physiol Rep, 2017;5(5):.
    Species: Mouse
    Sample Type: BALF
  20. Mitochondrial DNA-enriched microparticles promote acute-on-chronic alcoholic neutrophilia and hepatotoxicity
    Authors: Y Cai, MJ Xu, EH Koritzinsk, Z Zhou, W Wang, H Cao, PS Yuen, RA Ross, RA Star, S Liangpunsa, B Gao
    JCI Insight, 2017;2(14):.
    Species: Mouse
    Sample Type: Serum
  21. Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy
    Authors: EE To, R Vlahos, R Luong, ML Halls, PC Reading, PT King, C Chan, GR Drummond, CG Sobey, BRS Broughton, MR Starkey, R van der Sl, SR Lewin, S Bozinovski, LAJ O'Neill, T Quach, CJH Porter, DA Brooks, JJ O'Leary, S Selemidis
    Nat Commun, 2017;8(1):69.
    Species: Mouse
    Sample Type: BALF
  22. Interleukin-1 receptor in seizure susceptibility after traumatic injury to the pediatric brain
    Authors: BD Semple, TJ O'Brien, K Gimlin, DK Wright, S Eun Kim, PM Casillas-E, KM Webster, S Petrou, LJ Noble-Haeu
    J. Neurosci., 2017;0(0):.
    Species: Mouse
    Sample Type: Serum
  23. Regulation of Arthritis Severity by the Acid Sphingomyelinase
    Authors: N Beckmann, KA Becker, S Walter, JU Becker, M Kramer, G Hessler, S Weber, JR Göthert, K Fassbender, E Gulbins, A Carpinteir
    Cell. Physiol. Biochem., 2017;43(4):1.
    Species: Mouse
    Sample Type: Tissue Homogenates
  24. Circulating soluble endoglin modifies the inflammatory response in mice
    Authors: L Ruiz-Remol, C Ollauri-Ib, L Pérez-Roqu, E Núñez-Góme, F Pérez-Barr, JM López-Novo, M Pericacho, A Rodríguez-
    PLoS ONE, 2017;12(11):e0188204.
    Species: Mouse
    Sample Type: Plasma
  25. Xenotransplantation of layer-by-layer encapsulated non-human primate islets with a specified immunosuppressive drug protocol
    Authors: MR Haque, J Kim, H Park, HS Lee, KW Lee, TA Al-Hilal, JH Jeong, CH Ahn, DS Lee, SJ Kim, Y Byun
    J Control Release, 2017;0(0):.
    Species: Mouse
    Sample Type: Serum
  26. Succinate and its G-protein-coupled receptor stimulates osteoclastogenesis
    Authors: Y Guo, C Xie, X Li, J Yang, T Yu, R Zhang, T Zhang, D Saxena, M Snyder, Y Wu, X Li
    Nat Commun, 2017;8(0):15621.
    Species: Mouse
    Sample Type: Serum
    Application: data reported
  27. Intravenous hMSCs Ameliorate Acute Pancreatitis in Mice via Secretion of Tumor Necrosis Factor-? Stimulated Gene/Protein 6
    Sci Rep, 2016;6(0):38438.
    Species: Mouse
    Sample Type: Serum
  28. DNMT1-PPAR? pathway in macrophages regulates chronic inflammation and atherosclerosis development in mice
    Sci Rep, 2016;6(0):30053.
    Species: Mouse
    Sample Type: Plasma
  29. A Critical Role for P2X7 Receptor-Induced VCAM-1 Shedding and Neutrophil Infiltration during Acute Lung Injury
    J Immunol, 2016;0(0):.
  30. Toll-Like Receptor 4 Signaling Pathway Mediates Inhalant Organic Dust-Induced Bone Loss
    PLoS ONE, 2016;11(8):e0158735.
    Species: Mouse
    Sample Type: BALF
  31. C-type Lectin Mincle Recognizes Glucosyl-diacylglycerol of Streptococcus pneumoniae and Plays a Protective Role in Pneumococcal Pneumonia
    PLoS Pathog, 2016;12(12):e1006038.
    Species: Mouse
    Sample Type: Tissue Homogenates
  32. Kruppel-like factor 6 promotes macrophage-mediated inflammation by suppressing B cell leukemia/lymphoma 6 expression
    J Biol Chem, 2016;0(0):.
    Species: Mouse
    Sample Type: Tissue Homogenates
  33. Protective effect of Cl-amidine against CLP-induced lethal septic shock in mice
    Sci Rep, 2016;6(0):36696.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  34. Simvastatin promotes NPC1-mediated free cholesterol efflux from lysosomes through CYP7A1/LXR? signalling pathway in oxLDL-loaded macrophages
    J Cell Mol Med, 2016;0(0):.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  35. KLHDC10 Deficiency Protects Mice against TNF?-Induced Systemic Inflammation
    PLoS ONE, 2016;11(9):e0163118.
    Species: Mouse
    Sample Type: Serum
  36. Key role for neutrophils in radiation-induced antitumor immune responses: Potentiation with G-CSF
    Proc Natl Acad Sci USA, 2016;0(0):.
    Species: Mouse
    Sample Type: Tissue Homogenates
  37. Pyrin inflammasome activation and RhoA signaling in the autoinflammatory diseases FMF and HIDS
    Authors: Yong Hwan Park
    Nat Immunol, 2016;0(0):.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  38. Neutrophils suppress intraluminal NK-mediated tumor cell clearance and enhance extravasation of disseminated carcinoma cells
    Authors: A Spiegel, MW Brooks, S Houshyar, F Reinhardt, M Ardolino, E Fessler, MB Chen, JA Krall, J DeCock, IK Zervantona, A Iannello, Y Iwamoto, V Cortez-Ret, RD Kamm, MJ Pittet, DH Raulet, RA Weinberg
    Cancer Discov, 2016;0(0):.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  39. Adverse Effect Profile of Topical Ocular Administration of Fingolimod for Treatment of Dry Eye Disease
    Authors: Weibao Xiao
    Basic Clin. Pharmacol. Toxicol, 2016;0(0):.
    Species: Mouse
    Sample Type: Tears
  40. Novel Noncompetitive IL-1 Receptor-Biased Ligand Prevents Infection- and Inflammation-Induced Preterm Birth.
    Authors: Nadeau-Vallee M, Quiniou C, Palacios J, Hou X, Erfani A, Madaan A, Sanchez M, Leimert K, Boudreault A, Duhamel F, Rivera J, Zhu T, Noueihed B, Robertson S, Ni X, Olson D, Lubell W, Girard S, Chemtob S
    J Immunol, 2015;195(7):3402-15.
    Species: Mouse
    Sample Type: Plasma
  41. Microglial Heparan Sulfate Proteoglycans Facilitate the Cluster-of-Differentiation 14 (CD14)/Toll-like Receptor 4 (TLR4)-Dependent Inflammatory Response.
    Authors: O'Callaghan P, Li J, Lannfelt L, Lindahl U, Zhang X
    J Biol Chem, 2015;290(24):14904-14.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  42. Sharpin Controls Osteogenic Differentiation of Mesenchymal Bone Marrow Cells.
    Authors: Jeschke A, Catala-Lehnen P, Sieber S, Bickert T, Schweizer M, Koehne T, Wintges K, Marshall R, Mautner A, Duchstein L, Otto B, Horst A, Amling M, Kreienkamp H, Schinke T
    J Immunol, 2015;195(8):3675-84.
    Species: Mouse
    Sample Type: Serum
  43. RIP3-mediated necrotic cell death accelerates systematic inflammation and mortality.
    Authors: Meng L, Jin W, Wang X
    Proc Natl Acad Sci U S A, 2015;112(35):11007-12.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  44. Pycnogenol Attenuates the Release of Proinflammatory Cytokines and Expression of Perilipin 2 in Lipopolysaccharide-Stimulated Microglia in Part via Inhibition of NF-kappaB and AP-1 Activation.
    Authors: Fan B, Dun S, Gu J, Guo Y, Ikuyama S
    PLoS ONE, 2015;10(9):e0137837.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  45. Critical role for IL-18 in spontaneous lung inflammation caused by autophagy deficiency.
    Authors: Abdel Fattah E, Bhattacharya A, Herron A, Safdar Z, Eissa N
    J Immunol, 2015;194(11):5407-16.
  46. Accelerated tumor progression in mice lacking the ATP receptor P2X7.
    Authors: Adinolfi E, Capece M, Franceschini A, Falzoni S, Giuliani A, Rotondo A, Sarti A, Bonora M, Syberg S, Corigliano D, Pinton P, Jorgensen N, Abelli L, Emionite L, Raffaghello L, Pistoia V, Di Virgilio F
    Cancer Res, 2015;75(4):635-44.
    Species: Mouse
    Sample Type: Plasma
  47. Methylsulfonylmethane inhibits NLRP3 inflammasome activation.
    Authors: Ahn H, Kim J, Lee M, Kim Y, Cho Y, Lee G
    Cytokine, 2015;71(2):223-31.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  48. Chronic morphine-induced microRNA-124 promotes microglial immunosuppression by modulating P65 and TRAF6.
    Authors: Qiu S, Feng Y, LeSage G, Zhang Y, Stuart C, He L, Li Y, Caudle Y, Peng Y, Yin D
    J Immunol, 2015;194(3):1021-30.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  49. Local immunosuppressive microenvironment enhances migration of melanoma cells to lungs in DJ-1 knockout mice.
    Authors: Chien C, Lee M, Liou H, Liou H, Fu W
    PLoS ONE, 2015;10(2):e0115827.
    Species: Mouse
    Sample Type: Tissue Homogenates
  50. Sevoflurane inhibits nuclear factor-kappaB activation in lipopolysaccharide-induced acute inflammatory lung injury via toll-like receptor 4 signaling.
    Authors: Sun X, Li X, Wang X, Tan W, Wang J
    PLoS ONE, 2015;10(4):e0122752.
    Species: Mouse
    Sample Type: BALF
  51. Neurodegeneration by activation of the microglial complement-phagosome pathway.
    Authors: Bodea L, Wang Y, Linnartz-Gerlach B, Kopatz J, Sinkkonen L, Musgrove R, Kaoma T, Muller A, Vallar L, Di Monte D, Balling R, Neumann H
    J Neurosci, 2014;34(25):8546-56.
    Species: Mouse
    Sample Type: Plasma
  52. Akt2 deficiency protects from acute lung injury via alternative macrophage activation and miR-146a induction in mice.
    Authors: Vergadi, Eleni, Vaporidi, Katerina, Theodorakis, Emmanuel, Doxaki, Christin, Lagoudaki, Eleni, Ieronymaki, Elefther, Alexaki, Vassilia, Helms, Mike, Kondili, Eumorfia, Soennichsen, Birte, Stathopoulos, Efstathi, Margioris, Andrew N, Georgopoulos, Dimitrio, Tsatsanis, Christos
    J Immunol, 2014;192(1):394-406.
    Species: Mouse
    Sample Type: BALF
  53. Celecoxib sensitizes Staphylococcus aureus to antibiotics in macrophages by modulating SIRT1.
    Authors: Annamanedi M, Kalle A
    PLoS ONE, 2014;9(6):e99285.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  54. Differences in PGE2 production between primary human monocytes and differentiated macrophages: role of IL-1beta and TRIF/IRF3.
    Authors: Endo Y, Blinova K, Romantseva T, Golding H, Zaitseva M
    PLoS ONE, 2014;9(5):e98517.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  55. Diisopropylamine dichloroacetate, a novel pyruvate dehydrogenase kinase 4 inhibitor, as a potential therapeutic agent for metabolic disorders and multiorgan failure in severe influenza.
    Authors: Yamane, Kazuhiko, Indalao, Irene L, Chida, Junji, Yamamoto, Yoshikaz, Hanawa, Masaaki, Kido, Hiroshi
    PLoS ONE, 2014;9(5):e98032.
    Species: Mouse
    Sample Type: Tissue Homogenates
  56. Macrophage control of phagocytosed mycobacteria is increased by factors secreted by alveolar epithelial cells through nitric oxide independent mechanisms.
    Authors: Petursdottir D, Chuquimia O, Freidl R, Fernandez C
    PLoS ONE, 2014;9(8):e103411.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  57. The effects of protein malnutrition on the TNF-RI and NF-kappaB expression via the TNF-alpha signaling pathway.
    Authors: de Oliveira D, Hastreiter A, Mello A, de Oliveira Beltran J, Oliveira Santos E, Borelli P, Fock R
    Cytokine, 2014;69(2):218-25.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  58. CCL3 production by microglial cells modulates disease severity in murine models of retinal degeneration.
    Authors: Kohno H, Maeda T, Perusek L, Pearlman E, Maeda A
    J Immunol, 2014;192(8):3816-27.
    Species: Mouse
    Sample Type: Tissue Homogenates
  59. NF-kappaB signaling modulates radiationinduced microglial activation.
    Authors: Xue J, Dong J, Huang G, Qu X, Wu G, Dong X
    Oncol Rep, 2014;31(6):2555-60.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  60. Edwardsiella tarda-Induced cytotoxicity depends on its type III secretion system and flagellin.
    Authors: Xie H, Lu J, Rolhion N, Holden D, Nie P, Zhou Y, Yu X
    Infect Immun, 2014;82(8):3436-45.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  61. The inflammasome pyrin contributes to pertussis toxin-induced IL-1beta synthesis, neutrophil intravascular crawling and autoimmune encephalomyelitis.
    Authors: Dumas A, Amiable N, de Rivero Vaccari J, Chae J, Keane R, Lacroix S, Vallieres L
    PLoS Pathog, 2014;10(5):e1004150.
    Species: Mouse
    Sample Type: Peritoneal Fluid
  62. CCR1 inhibition ameliorates the progression of lupus nephritis in NZB/W mice.
    Authors: Bignon A, Gaudin F, Hemon P, Tharinger H, Mayol K, Walzer T, Loetscher P, Peuchmaur M, Berrebi D, Balabanian K
    J Immunol, 2014;192(3):886-96.
    Species: Mouse
    Sample Type: Serum
  63. PKM2 regulates the Warburg effect and promotes HMGB1 release in sepsis.
    Authors: Yang L, Xie M, Yang M, Yu Y, Zhu S, Hou W, Kang R, Lotze M, Billiar T, Wang H, Cao L, Tang D
    Nat Commun, 2014;5(0):4436.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  64. Running exercise alleviates trabecular bone loss and osteopenia in hemizygous beta-globin knockout thalassemic mice.
    Authors: Thongchote K, Svasti S, Teerapornpuntakit J, Krishnamra N, Charoenphandhu N
    Am J Physiol Endocrinol Metab, 2014;306(12):E1406-17.
    Species: Mouse
    Sample Type: Serum
  65. Role of TLR5 and flagella in bacillus intraocular infection.
    Authors: Parkunan, Salai Ma, Astley, Roger, Callegan, Michelle
    PLoS ONE, 2014;9(6):e100543.
    Species: Mouse
    Sample Type: Tissue Homogenates
  66. Improvement of spinal non-viral IL-10 gene delivery by D-mannose as a transgene adjuvant to control chronic neuropathic pain.
    Authors: Dengler E, Alberti L, Bowman B, Kerwin A, Wilkerson J, Moezzi D, Limanovich E, Wallace J, Milligan E
    J Neuroinflammation, 2014;11(0):92.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  67. Impaired bone formation and increased osteoclastogenesis in mice lacking chemokine (C-C motif) ligand 5 (Ccl5).
    Authors: Wintges K, Beil F, Albers J, Jeschke A, Schweizer M, Claass B, Tiegs G, Amling M, Schinke T
    J Bone Miner Res, 2013;28(10):2070-80.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  68. Spironolactone attenuates bleomycin-induced pulmonary injury partially via modulating mononuclear phagocyte phenotype switching in circulating and alveolar compartments.
    Authors: Ji W, Ma Y, Zhou X, Zhang Y, Lu R, Guo Z, Sun H, Hu D, Yang G, Li Y, Wei L
    PLoS ONE, 2013;8(11):e81090.
    Species: Mouse
    Sample Type: BALF
  69. Staphylococcus aureus sarA regulates inflammation and colonization during central nervous system biofilm formation.
    Authors: Snowden J, Beaver M, Beenken K, Smeltzer M, Horswill A, Kielian T
    PLoS ONE, 2013;8(12):e84089.
    Species: Mouse
    Sample Type: Tissue Homogenates
  70. Targeted inhibition of serotonin type 7 (5-HT7) receptor function modulates immune responses and reduces the severity of intestinal inflammation.
    Authors: Kim, Janice J, Bridle, Byram W, Ghia, Jean-Eri, Wang, Huaqing, Syed, Shahzad, Manocha, Marcus M, Rengasamy, Palanive, Shajib, Mohammad, Wan, Yonghong, Hedlund, Peter B, Khan, Waliul I
    J Immunol, 2013;190(9):4795-804.
    Species: Mouse
    Sample Type: Tissue Homogenates
  71. mTORC1 and mTORC2 play different roles in the functional survival of transplanted adipose-derived stromal cells in hind limb ischemic mice via regulating inflammation in vivo.
    Authors: Fan W, Cheng K, Qin X, Narsinh K, Wang S, Hu S, Wang Y, Chen Y, Wu J, Xiong L, Cao F
    Stem Cells, 2013;31(1):203-14.
    Species: Mouse
    Sample Type: Tissue Homogenates
  72. A hydrogen sulfide-releasing cyclooxygenase inhibitor markedly accelerates recovery from experimental spinal cord injury.
    Authors: Campolo M, Esposito E, Ahmad A, Di Paola R, Wallace J, Cuzzocrea S
    FASEB J, 2013;27(11):4489-99.
    Species: Mouse
    Sample Type: Whole Tissue
  73. Sufficient production of geranylgeraniol is required to maintain endotoxin tolerance in macrophages.
    Authors: Kim J, Lee J, Ye J, Hao R, Debose-Boyd R, Ye J
    J Lipid Res, 2013;54(12):3430-7.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  74. Bcl-2 overexpression ameliorates immune complex-mediated arthritis by altering FcgammaRIIb expression and monocyte homeostasis.
    Authors: Lawlor K, van Nieuwenhuijze A, Parker K, Drake S, Campbell I, Smith S, Vince J, Strasser A, Wicks I
    J Leukoc Biol, 2013;93(4):585-97.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  75. CXCL6 antibody neutralization prevents lung inflammation and fibrosis in mice in the bleomycin model.
    Authors: Besnard A, Struyf S, Guabiraba R, Fauconnier L, Rouxel N, Proost P, Uyttenhove C, Van Snick J, Couillin I, Ryffel B
    J Leukoc Biol, 2013;94(6):1317-23.
    Species: Mouse
    Sample Type: Tissue Homogenates
  76. Sirt2 suppresses inflammatory responses in collagen-induced arthritis.
    Authors: Lin J, Sun B, Jiang C, Hong H, Zheng Y
    Biochem Biophys Res Commun, 2013;441(4):897-903.
    Species: Mouse
    Sample Type: Serum
  77. NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice.
    Authors: Heneka M, Kummer M, Stutz A, Delekate A, Schwartz S, Vieira-Saecker A, Griep A, Axt D, Remus A, Tzeng T, Gelpi E, Halle A, Korte M, Latz E, Golenbock D
    Nature, 2013;493(7434):674-8.
    Species: Mouse
    Sample Type: Tissue Homogenates
  78. The axonal guidance receptor neogenin promotes acute inflammation.
    Authors: Konig K, Gatidou D, Granja T, Meier J, Rosenberger P, Mirakaj V
    PLoS ONE, 2012;7(3):e32145.
    Species: Mouse
    Sample Type: Peritoneal Lavage
  79. Toll-like receptor-mediated inhibition of Gas6 and ProS expression facilitates inflammatory cytokine production in mouse macrophages.
    Authors: Deng T, Zhang Y, Chen Q, Yan K, Han D
    Immunology, 2012;135(1):40-50.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  80. Netrin-1 protects against L-Arginine-induced acute pancreatitis in mice.
    Authors: Chen J, Cai Q, Shen P, Yan R, Wang C, Yang D, Fu H, Chen X
    PLoS ONE, 2012;7(9):e46201.
    Species: Mouse
    Sample Type: Plasma
  81. Exendin-4 protected against cognitive dysfunction in hyperglycemic mice receiving an intrahippocampal lipopolysaccharide injection.
    Authors: Huang H, Chen Y, Liang K, Jheng Y, Jhao J, Su M, Lee-Chen G, Hsieh-Li H
    PLoS ONE, 2012;7(7):e39656.
    Species: Mouse
    Sample Type: Plasma
  82. Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1.
    Authors: Broz P, Ruby T, Belhocine K, Bouley D, Kayagaki N, Dixit V, Monack D
    Nature, 2012;490(7419):288-91.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  83. Inhibiting Mer receptor tyrosine kinase suppresses STAT1, SOCS1/3, and NF-kappaB activation and enhances inflammatory responses in lipopolysaccharide-induced acute lung injury.
    J. Cell. Sci., 2012;91(6):921-32.
    Species: Mouse
    Sample Type: BALF
  84. Modelling of mouse experimental colitis by global property screens: a holistic approach to assess drug effects in inflammatory bowel disease.
    Authors: Gottfries J, Melgar S, Michaelsson E
    PLoS ONE, 2012;7(1):e30005.
    Species: Mouse
    Sample Type: Tissue Homogenates
  85. Activated protein C inhibits pancreatic islet inflammation, stimulates T regulatory cells, and prevents diabetes in non-obese diabetic (NOD) mice.
    Authors: Xue M, Dervish S, Harrison LC, Fulcher G, Jackson CJ
    J. Biol. Chem., 2012;287(20):16356-64.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  86. Dual functions of prostaglandin D2 in murine contact hypersensitivity via DP and CRTH2.
    Authors: Yamamoto Y, Otani S, Hirai H, Nagata K, Aritake K, Urade Y, Narumiya S, Yokozeki H, Nakamura M, Satoh T
    Am. J. Pathol., 2012;179(1):302-14.
    Species: Mouse
    Sample Type: Tissue Homogenates
  87. Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth.
    Authors: Bruchard M, Mignot G, Derangere V, Chalmin F, Chevriaux A, Vegran F, Boireau W, Simon B, Ryffel B, Connat J, Kanellopoulos J, Martin F, Rebe C, Apetoh L, Ghiringhelli F
    Nat Med, 2012;19(1):57-64.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  88. Treatment of diabetic mice with undenatured whey protein accelerates the wound healing process by enhancing the expression of MIP-1alpha, MIP-2, KC, CX3CL1 and TGF-beta in wounded tissue.
    BMC Immunol., 2012;13(0):32.
    Species: Mouse
    Sample Type: Tissue Homogenates
  89. WNT5A Signaling Contributes to Abeta-Induced Neuroinflammation and Neurotoxicity.
    Authors: Li B, Zhong L, Yang X, Andersson T, Huang M, Tang SJ
    PLoS ONE, 2011;6(8):e22920.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  90. Serotonin activates dendritic cell function in the context of gut inflammation.
    Authors: Li N, Ghia JE, Wang H, McClemens J, Cote F, Suehiro Y, Mallet J, Khan WI
    Am. J. Pathol., 2011;178(2):662-71.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  91. Action at a distance: systemically administered adult stem/progenitor cells (MSCs) reduce inflammatory damage to the cornea without engraftment and primarily by secretion of TNF-alpha stimulated gene/protein 6.
    Authors: Roddy GW, Oh JY, Lee RH, Bartosh TJ, Ylostalo J, Coble K, Rosa RH, Prockop DJ
    Stem Cells, 2011;29(10):1572-9.
    Species: Mouse
    Sample Type: Tissue Homogenates
  92. Repulsive guidance molecule-A (RGM-A) inhibits leukocyte migration and mitigates inflammation.
    Authors: Mirakaj V, Brown S, Laucher S, Steinl C, Klein G, Kohler D, Skutella T, Meisel C, Brommer B, Rosenberger P, Schwab JM
    Proc. Natl. Acad. Sci. U.S.A., 2011;108(16):6555-60.
    Species: Mouse
    Sample Type: Peritoneal Lavage
  93. Histone Deacetylase Inhibitor LAQ824 Augments Inflammatory Responses in Macrophages through Transcriptional Regulation of IL-10.
    Authors: Wang H, Cheng F
    J. Immunol., 2011;186(0):3986.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  94. Transgenic expression of human cathepsin B promotes progression and metastasis of polyoma-middle-T-induced breast cancer in mice.
    Authors: Sevenich L, Werner F, Gajda M, Schurigt U, Sieber C, Muller S, Follo M, Peters C, Reinheckel T
    Oncogene, 2011;30(1):54-64.
    Species: Mouse
    Sample Type: Tissue Homogenates
  95. HIF-VEGF pathways are critical for chronic otitis media in Junbo and Jeff mouse mutants.
    Authors: Cheeseman MT, Tyrer HE, Williams D, Hough TA, Pathak P, Romero MR, Hilton H, Bali S, Parker A, Vizor L, Purnell T, Vowell K, Wells S, Bhutta MF, Potter PK, Brown SD
    PLoS Genet., 2011;7(10):e1002336.
    Species: Mouse
    Sample Type: Serum
  96. Role of IL-1alpha and the Nlrp3/caspase-1/IL-1beta axis in cigarette smoke-induced pulmonary inflammation and COPD.
    Authors: Pauwels NS, Bracke KR, Dupont LL, Van Pottelberge GR, Provoost S, Vanden Berghe T, Vandenabeele P, Lambrecht BN, Joos GF, Brusselle GG
    Eur. Respir. J., 2011;38(5):1019-28.
    Species: Mouse
    Sample Type: BALF
  97. Deletion of tristetraprolin caused spontaneous reactive granulopoiesis by a non-cell-autonomous mechanism without disturbing long-term hematopoietic stem cell quiescence.
    Authors: Kaplan IM, Morisot S, Heiser D, Cheng WC, Kim MJ, Civin CI
    J. Immunol., 2011;186(5):2826-34.
    Species: Mouse
    Sample Type: Plasma
  98. Crawling Phagocytes Recruited in the Brain Vasculature after Pertussis Toxin Exposure through IL6, ICAM1 and ITGalphaM.
    Authors: Richard JF, Roy M, Audoy-Remus J, Tremblay P, Vallieres L
    Brain Pathol., 2011;21(0):661.
    Species: Mouse
    Sample Type: Serum
  99. Anti-inflammatory role of microsomal prostaglandin E synthase-1 in a model of neuroinflammation.
    Authors: Brenneis C, Coste O, Altenrath K, Angioni C, Schmidt H, Schuh CD, Zhang DD, Henke M, Weigert A, Brune B, Rubin B, Nusing R, Scholich K, Geisslinger G
    J. Biol. Chem., 2011;286(3):2331-42.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  100. Sphingosine regulates the NLRP3-inflammasome and IL-1beta release from macrophages.
    Authors: Luheshi NM, Giles JA, Lopez-Castejon G, Brough D
    Eur. J. Immunol., 2011;42(3):716-25.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  101. IL-33-activated dendritic cells are critical for allergic airway inflammation.
    Authors: Besnard AG, Togbe D, Guillou N, Erard F, Quesniaux V, Ryffel B
    Eur. J. Immunol., 2011;41(6):1675-86.
    Species: Mouse
    Sample Type: BALF
  102. TLR4 through IFN-beta promotes low molecular mass hyaluronan-induced neutrophil apoptosis.
    Authors: Leu SW, Shi L, Xu C, Zhao Y, Liu B, Li Y, Shiedlin A, Xiang C, Shen H, Quinn DA, Hales CA, Zhao H
    J. Immunol., 2011;186(1):556-62.
    Species: Mouse
    Sample Type: BALF
  103. Fasting induces an anti-inflammatory effect on the neuroimmune system which a high-fat diet prevents.
    Authors: Lavin DN, Joesting JJ, Chiu GS, Moon ML, Meng J, Dilger RN, Freund GG
    Obesity (Silver Spring), 2011;19(8):1586-94.
    Species: Mouse
    Sample Type: Serum
  104. Aryl hydrocarbon receptor deficiency in T cells suppresses the development of collagen-induced arthritis.
    Authors: Nakahama T, Kimura A, Nguyen NT, Chinen I, Hanieh H, Nohara K, Fujii-Kuriyama Y, Kishimoto T
    Proc. Natl. Acad. Sci. U.S.A., 2011;108(34):14222-7.
    Species: Mouse
    Sample Type: Serum
  105. Galectin-3 contributes to neonatal hypoxic-ischemic brain injury.
    Authors: Doverhag C, Hedtjarn M, Poirier F, Mallard C, Hagberg H, Karlsson A, Savman K
    Neurobiol. Dis., 2010;38(1):36-46.
    Species: Mouse
    Sample Type: Tissue Homogenates
  106. Early protection from burn-induced acute lung injury by deletion of preprotachykinin-A gene.
    Authors: Sio SW, Moochhala S, Lu J
    Am. J. Respir. Crit. Care Med., 2010;181(1):36-46.
    Species: Mouse
    Sample Type: Tissue Homogenates
  107. Cytotoxins of the human pathogen Aeromonas hydrophila trigger, via the NLRP3 inflammasome, caspase-1 activation in macrophages.
    Authors: McCoy AJ, Koizumi Y, Toma C, Higa N, Dixit V, Taniguchi S, Tschopp J, Suzuki T
    Eur. J. Immunol., 2010;40(10):2797-803.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  108. Evidence that intrathecal morphine-3-glucuronide may cause pain enhancement via toll-like receptor 4/MD-2 and interleukin-1beta.
    Authors: Lewis SS, Hutchinson MR, Rezvani N, Loram LC, Zhang Y, Maier SF, Rice KC, Watkins LR
    Neuroscience, 2010;165(2):569-83.
    Species: Mouse
    Sample Type: Cell Lysates
  109. TLR4 is a negative regulator in noninfectious lung inflammation.
    Authors: Zhao H, Leu SW, Shi L, Dedaj R, Zhao G, Garg HG, Shen L, Lien E, Fitzgerald KA, Shiedlin A, Shen H, Quinn DA, Hales CA
    J. Immunol., 2010;184(9):5308-14.
    Species: Mouse
    Sample Type: BALF
  110. Loss of ability to self-heal malaria upon taurine transporter deletion.
    Authors: Delic D, Warskulat U, Borsch E, Al-Qahtani S, Al-Quraishi S, Haussinger D, Wunderlich F
    Infect. Immun., 2010;78(4):1642-9.
    Species: Mouse
    Sample Type: Serum
  111. Absence or inhibition of matrix metalloproteinase-8 decreases ventilator-induced lung injury.
    Authors: Albaiceta GM, Gutierrez-Fernandez A, Garcia-Prieto E, Puente XS, Parra D, Astudillo A, Campestre C, Cabrera S, Gonzalez-Lopez A, Fueyo A, Taboada F, Lopez-Otin C
    Am. J. Respir. Cell Mol. Biol., 2010;43(5):555-63.
    Species: Mouse
    Sample Type: Tissue Homogenates
  112. Microbial exposure early in life regulates airway inflammation in mice after infection with Streptococcus pneumoniae with enhancement of local resistance.
    Authors: Yasuda Y, Matsumura Y, Kasahara K, Ouji N, Sugiura S, Mikasa K, Kita E
    Am. J. Physiol. Lung Cell Mol. Physiol., 2010;298(1):L67-78.
    Species: Mouse
    Sample Type: BALF
  113. Systemic inflammation sensitizes the neonatal brain to excitotoxicity through a pro-/anti-inflammatory imbalance: key role of TNFalpha pathway and protection by etanercept.
    Authors: Aden U, Favrais G, Plaisant F, Winerdal M, Felderhoff-Mueser U, Lampa J, Lelievre V, Gressens P
    Brain Behav. Immun., 2010;24(5):747-58.
    Species: Mouse
    Sample Type: Tissue Homogenates
  114. Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1beta in type 2 diabetes.
    Authors: Masters SL, Dunne A, Subramanian SL, Hull RL, Tannahill GM, Sharp FA, Becker C, Franchi L, Yoshihara E, Chen Z, Mullooly N, Mielke LA, Harris J, Coll RC, Mills KH, Mok KH, Newsholme P, Nunez G, Yodoi J, Kahn SE, Lavelle EC, O'Neill LA
    Nat. Immunol., 2010;11(10):897-904.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  115. Epithelial overexpression of SOCS-3 in transgenic mice exacerbates wound inflammation in the presence of elevated TGF-beta1.
    Authors: Linke A, Goren I, Bosl MR, Pfeilschifter J, Frank S
    J. Invest. Dermatol., 2010;130(3):866-75.
    Species: Mouse
    Sample Type: Tissue Homogenates
  116. A MyD88-dependent early IL-17 production protects mice against airway infection with the obligate intracellular pathogen Chlamydia muridarum.
    Authors: Zhang X, Gao L, Lei L, Zhong Y, Dube P, Berton MT, Arulanandam B, Zhang J, Zhong G
    J. Immunol., 2009;183(2):1291-300.
    Species: Mouse
    Sample Type: BALF
  117. Plasminogen activator inhibitor-1 regulates neutrophil influx during acute pyelonephritis.
    Authors: Roelofs JJ, Teske GJ, Bonta PI, de Vries CJ, Meijers JC, Weening JJ, van der Poll T, Florquin S
    Kidney Int., 2009;75(1):52-9.
    Species: Mouse
    Sample Type: Tissue Homogenates
  118. A small molecule CRTH2 antagonist inhibits FITC-induced allergic cutaneous inflammation.
    Authors: Boehme SA, Franz-Bacon K, Chen EP, Sasik R, Sprague LJ, Ly TW, Hardiman G, Bacon KB
    Int. Immunol., 2009;21(1):81-93.
    Species: Mouse
    Sample Type: Tissue Homogenates
  119. p47phox deficiency induces macrophage dysfunction resulting in progressive crystalline macrophage pneumonia.
    Authors: Liu Q, Cheng LI, Yi L, Zhu N, Wood A, Changpriroa CM, Ward JM, Jackson SH
    Am. J. Pathol., 2009;174(1):153-63.
    Species: Mouse
    Sample Type: BALF
  120. Secretory lysosome targeting and induced secretion of human soluble TNF-alpha receptor in murine hematopoietic cells in vivo as a principle for immunoregulation in inflammation and malignancy.
    Authors: Johansson AC, Nandakumar KS, Persson AM, Olsson I, Hansson M
    Exp. Hematol., 2009;37(8):969-78.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  121. Anti-inflammatory effects of ethyl acetate fraction from Melilotus suaveolens Ledeb on LPS-stimulated RAW 264.7 cells.
    Authors: Tao JY, Zheng GH, Zhao L, Wu JG, Zhang XY, Zhang SL, Huang ZJ, Xiong FL, Li CM
    J Ethnopharmacol, 2009;123(1):97-105.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  122. Tumor necrosis factor-alpha and interleukin-1 antagonists alleviate inflammatory skin changes associated with epidermal growth factor receptor antibody therapy in mice.
    Authors: Surguladze D, Deevi D, Claros N, Corcoran E, Wang S, Plym MJ, Wu Y, Doody J, Mauro DJ, Witte L, Busam KJ, Pytowski B, Rodeck U, Tonra JR
    Cancer Res., 2009;69(14):5643-7.
    Species: Mouse
    Sample Type: Tissue Homogenates
  123. VAMP8 is essential in anaphylatoxin-induced degranulation, TNF-alpha secretion, peritonitis, and systemic inflammation.
    Authors: Pushparaj PN, Tay HK, Wang CC, Hong W, Melendez AJ
    J. Immunol., 2009;183(2):1413-8.
    Species: Mouse
    Sample Type: Serum
  124. Syndecan-1 shedding facilitates the resolution of neutrophilic inflammation by removing sequestered CXC chemokines.
    Authors: Hayashida K, Parks WC, Park PW
    Blood, 2009;114(14):3033-43.
    Species: Mouse
    Sample Type: Serum
  125. Intravenous tolerance modulates macrophage classical activation and antigen presentation in experimental autoimmune encephalomyelitis.
    Authors: Li H, Ciric B, Yang J, Xu H, Fitzgerald DC, Elbehi M, Fonseca-Kelly Z, Yu S, Zhang GX, Rostami A
    J. Neuroimmunol., 2009;208(1):54-60.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  126. Inhibition of monocyte-derived inflammatory cytokines by IL-25 occurs via p38 Map kinase-dependent induction of Socs-3.
    Authors: Caruso R, Stolfi C, Sarra M, Rizzo A, Fantini MC, Pallone F, MacDonald TT, Monteleone G
    Blood, 2009;113(15):3512-9.
    Species: Mouse
    Sample Type: Serum
  127. Hypoxia-inducible factor-dependent induction of netrin-1 dampens inflammation caused by hypoxia.
    Authors: Rosenberger P, Schwab JM, Mirakaj V, Masekowsky E, Mager A, Morote-Garcia JC, Unertl K, Eltzschig HK
    Nat. Immunol., 2009;10(2):195-202.
    Species: Mouse
    Sample Type: Serum
  128. T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes.
    Authors: Guarda G, Dostert C, Staehli F, Cabalzar K, Castillo R, Tardivel A, Schneider P, Tschopp J
    Nature, 2009;460(7252):269-73.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  129. Differential IL-23 requirement for IL-22 and IL-17A production during innate immunity against Salmonella enterica serovar Enteritidis.
    Authors: Siegemund S, Schutze N, Schulz S, Wolk K, Nasilowska K, Straubinger RK, Sabat R, Alber G
    Int. Immunol., 2009;21(5):555-65.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  130. Bbeta(15-42) protects against acid-induced acute lung injury and secondary pseudomonas pneumonia in vivo.
    Authors: Matt U, Warszawska JM, Bauer M, Dietl W, Mesteri I, Doninger B, Haslinger I, Schabbauer G, Perkmann T, Binder CJ, Reingruber S, Petzelbauer P, Knapp S
    Am. J. Respir. Crit. Care Med., 2009;180(12):1208-17.
    Species: Mouse
    Sample Type: BALF
  131. Complement C3a regulates late asthmatic response and airway hyperresponsiveness in mice.
    Authors: Mizutani N, Nabe T, Yoshino S
    J. Immunol., 2009;183(6):4039-46.
    Species: Mouse
    Sample Type: BALF
  132. C/EBPalpha is required for pulmonary cytoprotection during hyperoxia.
    Authors: Xu Y, Saegusa C, Schehr A, Grant S, Whitsett JA, Ikegami M
    Am. J. Physiol. Lung Cell Mol. Physiol., 2009;297(2):L286-98.
    Species: Mouse
    Sample Type: Tissue Homogenates
  133. Inhibitory effect of atractylenolide I on angiogenesis in chronic inflammation in vivo and in vitro.
    Authors: Wang C, Duan H, He L
    Eur. J. Pharmacol., 2009;612(1):143-52.
    Species: Mouse
    Sample Type: Air Pouch Exudate
  134. Chrysanthemum indicum Linne extract inhibits the inflammatory response by suppressing NF-kappaB and MAPKs activation in lipopolysaccharide-induced RAW 264.7 macrophages.
    Authors: Cheon MS, Yoon T, Lee do Y, Choi G, Moon BC, Lee AY, Choo BK, Kim HK
    J Ethnopharmacol, 2009;122(3):473-7.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  135. Interleukin-1beta and fibroblast growth factor receptor 1 cooperate to induce cyclooxygenase-2 during early mammary tumourigenesis.
    Authors: Reed JR, Leon RP, Hall MK, Schwertfeger KL
    Breast Cancer Res., 2009;11(2):R21.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  136. NOD1 expression in the eye and functional contribution to IL-1beta-dependent ocular inflammation in mice.
    Authors: Rosenzweig HL, Galster KT, Planck SR, Rosenbaum JT
    Invest. Ophthalmol. Vis. Sci., 2009;50(4):1746-53.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  137. Myeloid Src kinases regulate phagocytosis and oxidative burst in pneumococcal meningitis by activating NADPH oxidase.
    Authors: Paul R, Obermaier B, Van Ziffle J, Angele B, Pfister HW, Lowell CA, Koedel U
    J. Leukoc. Biol., 2008;84(4):1141-50.
    Species: Mouse
    Sample Type: Tissue Homogenates
  138. Activation of NOD2 in vivo induces IL-1beta production in the eye via caspase-1 but results in ocular inflammation independently of IL-1 signaling.
    Authors: Rosenzweig HL, Martin TM, Planck SR, Galster K, Jann MM, Davey MP, Kobayashi K, Flavell RA, Rosenbaum JT
    J. Leukoc. Biol., 2008;84(2):529-36.
    Species: Mouse
    Sample Type: Tissue Homogenates
  139. Antifibrotic action of pirfenidone and prednisolone: different effects on pulmonary cytokines and growth factors in bleomycin-induced murine pulmonary fibrosis.
    Authors: Oku H, Shimizu T, Kawabata T, Nagira M, Hikita I, Ueyama A, Matsushima S, Torii M, Arimura A
    Eur. J. Pharmacol., 2008;590(1):400-8.
    Species: Mouse
    Sample Type: Tissue Homogenates
  140. CT20126, a novel immunosuppressant, prevents collagen-induced arthritis through the down-regulation of inflammatory gene expression by inhibiting NF-kappaB activation.
    Authors: Lee SJ, Nam WD, Na HJ, Cho YL, Ha KS, Hwang JY, Lee H, Kim SO, Kwon YG, Kim YM
    Biochem. Pharmacol., 2008;76(1):79-90.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  141. The neuropeptide substance P is a critical mediator of burn-induced acute lung injury.
    Authors: Sio SW, Puthia MK, Lu J, Moochhala S, Bhatia M
    J. Immunol., 2008;180(12):8333-41.
    Species: Mouse
    Sample Type: Tissue Homogenates
  142. Mouse models of rhinovirus-induced disease and exacerbation of allergic airway inflammation.
    Authors: Bartlett NW, Walton RP, Edwards MR, Aniscenko J, Caramori G, Zhu J, Glanville N, Choy KJ, Jourdan P, Burnet J, Tuthill TJ, Pedrick MS, Hurle MJ, Plumpton C, Sharp NA, Bussell JN, Swallow DM, Schwarze J, Guy B, Almond JW, Jeffery PK, Lloyd CM, Papi A, Killington RA, Rowlands DJ, Blair ED, Clarke NJ, Johnston SL
    Nat. Med., 2008;14(2):199-204.
    Species: Mouse
    Sample Type: BALF
  143. Inflamed phenotype of the mesenteric microcirculation of melanocortin type 3 receptor-null mice after ischemia-reperfusion.
    Authors: Leoni G, Patel HB, Sampaio AL, Gavins FN, Murray JF, Grieco P, Getting SJ, Perretti M
    FASEB J., 2008;22(12):4228-38.
    Species: Mouse
    Sample Type: Plasma
  144. Pharmacological and genetic inhibition of NADPH oxidase does not reduce brain damage in different models of perinatal brain injury in newborn mice.
    Authors: Doverhag C, Keller M, Karlsson A, Hedtjarn M, Nilsson U, Kapeller E, Sarkozy G, Klimaschewski L, Humpel C, Hagberg H, Simbruner G, Gressens P, Savman K
    Neurobiol. Dis., 2008;31(1):133-44.
    Species: Mouse
    Sample Type: Tissue Homogenates
  145. Endogenous hydrogen sulfide regulates inflammatory response by activating the ERK pathway in polymicrobial sepsis.
    Authors: Zhang H, Moochhala SM, Bhatia M
    J. Immunol., 2008;181(6):4320-31.
    Species: Mouse
    Sample Type: Tissue Homogenates
  146. Functional roles for C5a receptors in sepsis.
    Authors: Rittirsch D, Flierl MA, Nadeau BA, Day DE, Huber-Lang M, Mackay CR, Zetoune FS, Gerard NP, Cianflone K, Kohl J, Gerard C, Sarma JV, Ward PA
    Nat. Med., 2008;14(5):551-7.
    Species: Mouse
    Sample Type: Plasma
  147. Tumor-infiltrating myeloid-derived suppressor cells are pleiotropic-inflamed monocytes/macrophages that bear M1- and M2-type characteristics.
    Authors: Umemura N, Saio M, Suwa T, Kitoh Y, Bai J, Nonaka K, Ouyang GF, Okada M, Balazs M, Adany R, Shibata T, Takami T
    J. Leukoc. Biol., 2008;83(5):1136-44.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  148. Purine receptor antagonist modulates serology and affective behaviors in lupus-prone mice: evidence of autoimmune-induced pain?
    Authors: Ballok DA, Sakic B
    Brain Behav. Immun., 2008;0(0):.
    Species: Mouse
    Sample Type: Serum
  149. Tranilast, an orally active anti-allergic drug, up-regulates the anti-inflammatory heme oxygenase-1 expression but down-regulates the pro-inflammatory cyclooxygenase-2 and inducible nitric oxide synthase expression in RAW264.7 macrophages.
    Authors: Pae HO, Jeong SO, Koo BS, Ha HY, Lee KM, Chung HT
    Biochem. Biophys. Res. Commun., 2008;371(3):361-5.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  150. Peroxisome proliferator-activated receptor-gamma ligand, 15-deoxy-Delta12,14-prostaglandin J2, reduces neutrophil migration via a nitric oxide pathway.
    Authors: Napimoga MH, Vieira SM, Dal-Secco D, Freitas A, Souto FO, Mestriner FL, Alves-Filho JC, Grespan R, Kawai T, Ferreira SH, Cunha FQ
    J. Immunol., 2008;180(1):609-17.
    Species: Mouse
    Sample Type: Tissue Secretion
  151. Adverse functions of IL-17A in experimental sepsis.
    Authors: Flierl MA, Rittirsch D, Gao H, Hoesel LM, Nadeau BA, Day DE, Zetoune FS, Sarma JV, Huber-Lang MS, Ferrara JL, Ward PA
    FASEB J., 2008;22(7):2198-205.
    Species: Mouse
    Sample Type: Plasma
  152. The NALP3 inflammasome is involved in the innate immune response to amyloid-beta.
    Authors: Halle A, Hornung V, Petzold GC, Stewart CR, Monks BG, Reinheckel T, Fitzgerald KA, Latz E, Moore KJ, Golenbock DT
    Nat. Immunol., 2008;9(8):857-65.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  153. Interleukin-1beta is the primary initiator of pulmonary inflammation following liver injury in mice.
    Authors: Glasgow SC, Ramachandran S, Blackwell TS, Mohanakumar T, Chapman WC
    Am. J. Physiol. Lung Cell Mol. Physiol., 2007;293(2):L491-6.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  154. The immunomodulation of endotoxin-induced acute lung injury by hesperidin in vivo and in vitro.
    Authors: Yeh CC, Kao SJ, Lin CC, Wang SD, Liu CJ, Kao ST
    Life Sci., 2007;80(20):1821-31.
    Species: Mouse
    Sample Type: BALF
  155. Identification of an immune-responsive mesolimbocortical serotonergic system: potential role in regulation of emotional behavior.
    Authors: Lowry CA, Hollis JH, de Vries A, Pan B, Brunet LR, Hunt JR, Paton JF, van Kampen E, Knight DM, Evans AK, Rook GA, Lightman SL
    Neuroscience, 2007;146(2):756-72.
    Species: Mouse
    Sample Type: Plasma
  156. Acute brain injury triggers MyD88-dependent, TLR2/4-independent inflammatory responses.
    Authors: Koedel U, Merbt UM, Schmidt C, Angele B, Popp B, Wagner H, Pfister HW, Kirschning CJ
    Am. J. Pathol., 2007;171(1):200-13.
    Species: Mouse
    Sample Type: Tissue Homogenates
  157. Soluble vascular endothelial growth factor receptor-1 protects mice in sepsis.
    Authors: Tsao PN, Chan FT, Wei SC, Hsieh WS, Chou HC, Su YN, Chen CY, Hsu WM, Hsieh FJ, Hsu SM
    Crit. Care Med., 2007;35(8):1955-60.
    Species: Mouse
    Sample Type: Plasma
  158. Cathelicidin-deficient (Cnlp -/- ) mice show increased susceptibility to Pseudomonas aeruginosa keratitis.
    Authors: Huang LC, Reins RY, Gallo RL, McDermott AM
    Invest. Ophthalmol. Vis. Sci., 2007;48(10):4498-508.
    Species: Mouse
    Sample Type: Tissue Homogenates
  159. Astragali Radix elicits anti-inflammation via activation of MKP-1, concomitant with attenuation of p38 and Erk.
    Authors: Ryu M, Kim EH, Chun M, Kang S, Shim B, Yu YB, Jeong G, Lee JS
    J Ethnopharmacol, 2007;115(2):184-93.
    Species: Mouse
    Sample Type: Air Pouch Exudate
  160. ST2 is essential for Th2 responsiveness and resistance to pseudomonas aeruginosa keratitis.
    Authors: Huang X, Du W, Barrett RP, Hazlett LD
    Invest. Ophthalmol. Vis. Sci., 2007;48(10):4626-33.
    Species: Mouse
    Sample Type: Tissue Homogenates
  161. Toll-like receptor 4 (TLR4)-dependent proinflammatory and immunomodulatory properties of the glycoinositolphospholipid (GIPL) from Trypanosoma cruzi.
    Authors: Medeiros MM, Peixoto JR, Oliveira AC, Cardilo-Reis L, Koatz VL, Van Kaer L, Previato JO, Mendonca-Previato L, Nobrega A, Bellio M
    J. Leukoc. Biol., 2007;82(3):488-96.
    Species: Mouse
    Sample Type: Peritoneal Fluid
  162. Cell-based angiopoietin-1 gene therapy for acute lung injury.
    Authors: McCarter SD, Mei SH, Lai PF, Zhang QW, Parker CH, Suen RS, Hood RD, Zhao YD, Deng Y, Han RN, Dumont DJ, Stewart DJ
    Am. J. Respir. Crit. Care Med., 2007;175(10):1014-26.
    Species: Mouse
    Sample Type: BALF
  163. Mice lacking NKCC1 are protected from development of bacteremia and hypothermic sepsis secondary to bacterial pneumonia.
    Authors: Nguyen M, Pace AJ, Koller BH
    J. Exp. Med., 2007;204(6):1383-93.
    Species: Mouse
    Sample Type: Tissue Homogenates
  164. The direct action of 1alpha,25(OH)2-vitamin D3 on purified mouse Langerhans cells.
    Authors: Fujita H, Asahina A, Komine M, Tamaki K
    Cell. Immunol., 2007;245(2):70-9.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  165. Clostridium sordellii lethal toxin kills mice by inducing a major increase in lung vascular permeability.
    Authors: Geny B, Khun H, Fitting C, Zarantonelli L, Mazuet C, Cayet N, Szatanik M, Prevost MC, Cavaillon JM, Huerre M, Popoff MR
    Am. J. Pathol., 2007;170(3):1003-17.
    Species: Mouse
    Sample Type: Serum
  166. The flavonoid baicalin protects against cerebrovascular dysfunction and brain inflammation in experimental heatstroke.
    Authors: Chang CP, Huang WT, Cheng BC, Hsu CC, Lin MT
    Neuropharmacology, 2007;52(3):1024-33.
    Species: Mouse
    Sample Type: Serum
  167. Maternal immune activation alters fetal brain development through interleukin-6.
    Authors: Smith SE, Li J, Garbett K, Mirnics K, Patterson PH
    J. Neurosci., 2007;27(40):10695-702.
    Species: Mouse
    Sample Type: Serum
  168. Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock.
    Authors: Vogl T, Tenbrock K, Ludwig S, Leukert N, Ehrhardt C, van Zoelen MA, Nacken W, Foell D, van der Poll T, Sorg C, Roth J
    Nat. Med., 2007;13(9):1042-9.
    Species: Mouse
    Sample Type: Serum
  169. Toll-like receptor 4 mediates the early inflammatory response after cold ischemia/reperfusion.
    Authors: Kaczorowski DJ, Nakao A, Mollen KP, Vallabhaneni R, Sugimoto R, Kohmoto J, Tobita K, Zuckerbraun BS, McCurry KR, Murase N, Billiar TR
    Transplantation, 2007;84(10):1279-87.
    Species: Mouse
    Sample Type: Serum
  170. Neuronal NF-kappaB influences thermoregulation and survival in a sepsis model.
    Authors: Juttler E, Inta I, Eigler V, Herrmann O, Maegele I, Maser-Gluth C, Schwaninger M
    J. Neuroimmunol., 2007;189(1):41-9.
    Species: Mouse
    Sample Type: Serum
  171. CD27 contributes to the early systemic immune response to Mycobacterium tuberculosis infection but does not affect outcome.
    Authors: Wieland CW, Kerver ME, Florquin S, Nolte MA, Borst J, van Lier R, van Oers MH, van der Poll T
    Int. Immunol., 2006;18(11):1531-9.
  172. Citrus polymethoxylated flavones improve lipid and glucose homeostasis and modulate adipocytokines in fructose-induced insulin resistant hamsters.
    Authors: Li RW, Theriault AG, Au K, Douglas TD, Casaschi A, Kurowska EM, Mukherjee R
    Life Sci., 2006;79(4):365-73.
    Species: Mouse
    Sample Type: Serum
  173. Absence of IL-1 receptor antagonist impaired wound healing along with aberrant NF-kappaB activation and a reciprocal suppression of TGF-beta signal pathway.
    Authors: Ishida Y, Kondo T, Kimura A, Matsushima K, Mukaida N
    J. Immunol., 2006;176(9):5598-606.
    Species: Mouse
    Sample Type: Tissue Homogenates
  174. [D-Trp8]-gamma-melanocyte-stimulating hormone exhibits anti-inflammatory efficacy in mice bearing a nonfunctional MC1R (recessive yellow e/e mouse).
    Authors: Getting SJ, Lam CW, Leoni G, Gavins FN, Grieco P, Perretti M
    Mol. Pharmacol., 2006;70(6):1850-5.
    Species: Mouse
    Sample Type: Peritoneal Lavage
  175. The urokinase plasminogen activator receptor is crucially involved in host defense during acute pyelonephritis.
    Authors: Roelofs JJ, Rouschop KM, Teske GJ, Claessen N, Weening JJ, van der Poll T, Florquin S
    Kidney Int., 2006;70(11):1942-7.
    Species: Mouse
    Sample Type: Tissue Homogenates
  176. Organ-specific role of MyD88 for gene regulation during polymicrobial peritonitis.
    Authors: Weighardt H, Mages J, Jusek G, Kaiser-Moore S, Lang R, Holzmann B
    Infect. Immun., 2006;74(6):3618-32.
    Species: Mouse
    Sample Type: Tissue Homogenates
  177. Inhalation of ultrafine carbon particles triggers biphasic pro-inflammatory response in the mouse lung.
    Authors: Andre E, Stoeger T, Takenaka S, Bahnweg M, Ritter B, Karg E, Lentner B, Reinhard C, Schulz H, Wjst M
    Eur. Respir. J., 2006;28(2):275-85.
    Species: Mouse
    Sample Type: BALF
  178. Tetrathiomolybdate is effective in a mouse model of arthritis.
    Authors: McCubbin MD, Hou G, Abrams GD, Dick R, Brewer GJ
    J. Rheumatol., 2006;33(12):2501-6.
    Species: Mouse
    Sample Type: Serum
  179. Protease-activated receptor-2 activation: a major role in the pathogenesis of Porphyromonas gingivalis infection.
    Authors: Holzhausen M, Spolidorio LC, Ellen RP, Jobin MC, Steinhoff M, Andrade-Gordon P, Vergnolle N
    Am. J. Pathol., 2006;168(4):1189-99.
    Species: Mouse
    Sample Type: Blister Fluid
  180. Vaccinia virus infection attenuates innate immune responses and antigen presentation by epidermal dendritic cells.
    Authors: Deng L, Dai P, Ding W, Granstein RD, Shuman S
    J. Virol., 2006;80(20):9977-87.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  181. Allergic airway inflammation inhibits pulmonary antibacterial host defense.
    Authors: Beisswenger C, Kandler K, Hess C, Garn H, Felgentreff K, Wegmann M, Renz H, Vogelmeier C, Bals R
    J. Immunol., 2006;177(3):1833-7.
    Species: Mouse
    Sample Type: BALF
  182. Bim deficiency leads to exacerbation and prolongation of joint inflammation in experimental arthritis.
    Authors: Scatizzi JC, Bickel E, Hutcheson J, Haines GK, Perlman H
    Arthritis Rheum., 2006;54(10):3182-93.
    Species: Mouse
    Sample Type: Tissue Homogenates
  183. Gender differences in murine airway responsiveness and lipopolysaccharide-induced inflammation.
    Authors: Card JW, Carey MA, Bradbury JA, DeGraff LM, Morgan DL, Moorman MP, Flake GP, Zeldin DC
    J. Immunol., 2006;177(1):621-30.
    Species: Mouse
    Sample Type: BALF
  184. GM-CSF and the impaired pulmonary innate immune response following hyperoxic stress.
    Authors: Baleeiro CE, Christensen PJ, Morris SB, Mendez MP, Wilcoxen SE, Paine R
    Am. J. Physiol. Lung Cell Mol. Physiol., 2006;291(6):L1246-55.
    Species: Mouse
    Sample Type: Tissue Homogenates
  185. Endogenous interleukin-12 improves the early antimicrobial host response to murine Escherichia coli peritonitis.
    Authors: Weijer S, Florquin S, van der Poll T
    Shock, 2005;23(1):54-8.
    Species: Mouse
    Sample Type: Peritoneal Fluid
  186. The class A macrophage scavenger receptor attenuates CXC chemokine production and the early infiltration of neutrophils in sterile peritonitis.
    Authors: Cotena A, Platt N
    J. Immunol., 2004;173(10):6427-32.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  187. Cytokine expression in experimental chronic otitis media with effusion in mice.
    Authors: Maeda K, Hirano T, Ichimiya I, Kurono Y, Suzuki M, Mogi G
    Laryngoscope, 2004;114(11):1967-72.
    Species: Mouse
    Sample Type: Tissue Secretion
  188. Regulation of Pseudomonas aeruginosa corneal infection in IL-1 beta converting enzyme (ICE, caspase-1) deficient mice.
    Authors: Thakur A, Barrett RP, McClellan S, Hazlett LD
    Curr. Eye Res., 2004;29(4):225-33.
    Species: Mouse
    Sample Type: Tissue Homogenates
  189. Responses of guinea pig pups during isolation in a novel environment may represent stress-induced sickness behaviors.
    Authors: Hennessy MB, Deak T, Schiml-Webb PA, Wilson SE, Greenlee TM, McCall E
    Physiol. Behav., 2004;81(1):5-13.
    Species: Guinea Pig
    Sample Type: Serum
  190. IL-1 receptor-associated kinase 1 mediates protection against Staphylococcus aureus infection.
    Authors: Verdrengh M, Thomas JA, Hultgren OH
    Microbes Infect., 2004;6(14):1268-72.
    Species: Mouse
    Sample Type: Serum
  191. Systemic up-regulation of sTNFR2 and IL-6 in Porphyromonas gingivalis pneumonia in mice.
    Authors: Petelin M, Naruishi K, Shiomi N, Mineshiba J, Arai H, Nishimura F, Takashiba S, Murayama Y
    Exp. Mol. Pathol., 2004;76(1):76-81.
    Species: Mouse
    Sample Type: Serum
  192. T cell-specific ablation of Fas leads to Fas ligand-mediated lymphocyte depletion and inflammatory pulmonary fibrosis.
    Authors: Hao Z, Hampel B, Yagita H, Rajewsky K
    J. Exp. Med., 2004;199(10):1355-65.
    Species: Mouse
    Sample Type: Serum
  193. Suppression of graft coronary artery disease by a brief treatment with a selective epsilonPKC activator and a deltaPKC inhibitor in murine cardiac allografts.
    Authors: Tanaka M, Terry RD, Mokhtari GK, Inagaki K, Koyanagi T, Kofidis T, Mochly-Rosen D, Robbins RC
    Circulation, 2004;110(11):II194-9.
    Species: Mouse
    Sample Type: Tissue Homogenates
  194. Increased interleukin-10 associated with low IL-6 concentration correlated with greater survival rates in mice infected by rabies virus vaccinated against it and immunomodulated with P. acnes.
    Authors: Megid J, Kaneno R, Nozaki CN, Brito CJ, Almeida MF
    Comp. Immunol. Microbiol. Infect. Dis., 2004;27(6):393-411.
    Species: Mouse
    Sample Type: Serum
  195. Redundancy of a functional melanocortin 1 receptor in the anti-inflammatory actions of melanocortin peptides: studies in the recessive yellow (e/e) mouse suggest an important role for melanocortin 3 receptor.
    Authors: Getting SJ, Christian HC, Lam CW, Gavins FN, Flower RJ, Schioth HB, Perretti M
    J. Immunol., 2003;170(6):3323-30.
    Species: Mouse
    Sample Type: Peritoneal Fluid
  196. Interleukin-10 negatively regulates local cytokine and chemokine production but does not influence antibacterial host defense during murine pneumococcal meningitis.
    Authors: Zwijnenburg PJ, van der Poll T, Florquin S, Roord JJ, van Furth AM
    Infect. Immun., 2003;71(4):2276-9.
    Species: Mouse
    Sample Type: Tissue Homogenates
  197. Thrombomodulin mutant mice with a strongly reduced capacity to generate activated protein C have an unaltered pulmonary immune response to respiratory pathogens and lipopolysaccharide.
    Authors: Rijneveld AW, Weijer S, Florquin S, Esmon CT, Meijers JC, Speelman P, Reitsma PH, ten Cate H, van der Poll T
    Blood, 2003;103(5):1702-9.
    Species: Mouse
    Sample Type: BALF
  198. IL-17, produced by lymphocytes and neutrophils, is necessary for lipopolysaccharide-induced airway neutrophilia: IL-15 as a possible trigger.
    Authors: Ferretti S, Bonneau O, Dubois GR, Jones CE, Trifilieff A
    J. Immunol., 2003;170(4):2106-12.
    Species: Mouse
    Sample Type: BALF
  199. Caspase-1-deficient mice have delayed neutrophil apoptosis and a prolonged inflammatory response to lipopolysaccharide-induced acute lung injury.
    Authors: Rowe SJ, Allen L, Ridger VC, Hellewell PG, Whyte MK
    J. Immunol., 2002;169(11):6401-7.
    Species: Mouse
    Sample Type: BALF
  200. Dendritic cells phagocytose and are activated by Treponema pallidum.
    Authors: Bouis DA, Popova TG, Takashima A, Norgard MV
    Infect. Immun., 2001;69(1):518-28.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  201. The protein tyrosine kinase inhibitor AG126 prevents the massive microglial cytokine induction by pneumococcal cell walls.
    Authors: Hanisch UK, Prinz M, Angstwurm K, Hausler KG, Kann O, Kettenmann H, Weber JR
    Eur. J. Immunol., 2001;31(7):2104-15.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  202. Amyloid beta and amylin fibrils induce increases in proinflammatory cytokine and chemokine production by THP-1 cells and murine microglia.
    Authors: Yates SL, Burgess LH, Kocsis-Angle J, Antal JM, Dority MD, Embury PB, Piotrkowski AM, Brunden KR
    J. Neurochem., 2000;74(3):1017-25.
    Species: Mouse
    Sample Type: Cell Culture Supernates
  203. Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors.
    Authors: Babelova A, Moreth K, Tsalastra-Greul W, Zeng-Brouwers J, Eickelberg O, Young MF, Bruckner P, Pfeilschifter J, Schaefer RM, Schaefer R, Grone HJ, Schaefer L
    J Biol Chem, 0;284(36):24035-48.
    Species: Mouse
    Sample Type: Plasma
  204. Sustained interleukin-1beta overexpression exacerbates tau pathology despite reduced amyloid burden in an Alzheimer's mouse model.
    Authors: Ghosh S, Wu M, Shaftel S, Kyrkanides S, Laferla F, Olschowka J, O'Banion M
    J Neurosci, 0;33(11):5053-64.
    Species: Mouse
    Sample Type: Tissue Homogenates
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 Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit MLB00C Array MLB00C
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  Anonymous 05/08/2018
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 Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit MLB00C
: Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit [MLB00C].

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Sample Tested Heparin Plasma

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Other Experimental Details Among best ELISAs I've worked with. Great consistency lot to lot, high sensitivity, easy to work with small amount of samples (usually dilute mouse plasma 1:10). Appropriate for concentration response curves.
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  Anonymous 12/04/2017
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Sample Tested Cell culture supernatant

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 Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit MLB00C Array MLB00C
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  Anonymous 03/07/2017
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 Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit MLB00C
: Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit [MLB00C].

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Sample Tested Cell culture supernatant,Mouse Primary Monocytes

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