Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit

Catalog # Availability Size / Price Qty
SMLB00C
PMLB00C
MLB00C
Mouse IL-1 beta/IL-1F2 ELISA Standard Curve
2 Images
Product Details
Citations (284)
FAQs
Supplemental Products
Reviews (12)

Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit Summary

Assay Length
4.5 hours
Sample Type & Volume Required Per Well
Cell Culture Supernates (50 uL), Tissue Lysates (50 uL), Serum (50 uL), EDTA Plasma (50 uL), Heparin Plasma (50 uL)
Sensitivity
4.8 pg/mL
Assay Range
12.5 - 800 pg/mL (Cell Culture Supernates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma)
Specificity
Natural and recombinant mouse IL-1 beta
Cross-reactivity
< 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
Interference
No significant interference observed with available related molecules.

Product Summary

The Quantikine® Mouse IL-1 beta Immunoassay is a 4.5 hour solid phase ELISA designed to measure mouse IL-1 beta in cell culture supernates, tissue lysates, serum, and plasma. It contains E. coli-expressed recombinant mouse IL-1 beta and antibodies raised against the recombinant factor. This immunoassay has been shown to quantitate the recombinant factor accurately. Results obtained using natural mouse IL-1 beta showed dose-response curves that were parallel to the standard curves obtained using the recombinant kit standards. These results indicate that this kit can be used to determine relative mass values for natural mouse IL-1 beta.

Precision

Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision

Cell Culture Supernates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma

Intra-Assay Precision Inter-Assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 20 20 20
Mean 33.5 92.9 386 34.6 93.5 423
Standard Deviation 2.5 4.3 11.7 2.9 6.2 23.9
CV% 7.5 4.6 3 8.4 6.6 5.7

Recovery

The recovery of mouse IL-1 beta spiked to three levels throughout the range of the assay in various matrices was evaluated.

Sample Type Average % Recovery Range %
Cell Culture Supernates (n=4) 106 95-119
EDTA Plasma (n=4) 108 101-117
Heparin Plasma (n=4) 97 87-114
Serum (n=4) 105 98-113
Tissue Lysates (n=4) 115 110-120

Linearity

To assess the linearity of the assay, samples containing and/or spiked with high concentrations of mouse IL-1 beta were serially diluted with Calibrator Diluent to produce samples with values within the dynamic range of the assay.
Mouse IL-1 beta/IL-1F2 ELISA Linearity

Data Examples

Mouse IL-1 beta/IL-1F2 ELISA Standard Curve

Product Datasheets

Preparation and Storage

Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: IL-1 beta/IL-1F2

The Interleukin 1 (IL-1) family of proteins consists of IL-1 alpha, IL-1 beta, and the IL-1 receptor antagonist (IL-1ra). IL-1 alpha and IL-1 beta bind to the same cell surface receptors and share biological functions (1). IL-1 is not produced by unstimulated cells of healthy individuals with the exception of skin keratinocytes, some epithelial cells, and certain cells of the central nervous system. However, in response to inflammatory agents, infections, or microbial endotoxins, a dramatic increase in the production of IL-1 by macrophages and various other cell types is seen. IL-1 beta plays a central role in immune and inflammatory responses, bone remodeling, fever, carbohydrate metabolism, and GH/IGF-I physiology. Inappropriate or prolonged production of IL-1 has been implicated in a variety of pathological conditions including sepsis, rheumatoid arthritis, inflammatory bowel disease, acute and chronic myelogenous leukemia, insulindependent diabetes mellitus, atherosclerosis, neuronal injury, and aging-related diseases (2-5). 

 IL-1 alpha and IL-1 beta are structurally related polypeptides that show approximately 25% homology at the amino acid (aa) level. Both are synthesized as 31 kDa precursors that are subsequently cleaved into mature proteins of approximately 17.5 kDa (6, 7). Cleavage of the IL-1 beta precursor by Caspase-1/ICE is a key step in the inflammatory response (2, 8). Neither IL-1 alpha nor IL-1 beta contains a typical hydrophobic signal peptide (9-11), but evidence suggests that these factors can be secreted by non-classical pathways (12, 13). A portion of unprocessed IL-1 alpha can be presented on the cell membrane and may retain biological activity (14). The precursor form of IL-1 beta, unlike the IL-1 alpha precursor, shows little or no biological activity in comparison to the processed form (13, 15). Both unprocessed and mature forms of IL-1 beta are exported from the cell. 
 IL-1 alpha and IL-1 beta exert their effects through immunoglobulin superfamily receptors that additionally bind IL-1ra. The 80 kDa transmembrane type I receptor (IL-1 RI) is expressed on T cells, fibroblasts, keratinocytes, endothelial cells, synovial lining cells, chondrocytes, and hepatocytes (16, 17). The 68 kDa transmembrane type II receptor (IL-1 RII) is expressed on B cells, neutrophils, and bone marrow cells (18). The two IL-1 receptor types show approximately 28% homology in their extracellular domains but differ significantly in that the type II receptor has a cytoplasmic domain of only 29 aa, whereas the type I receptor has a 213 aa cytoplasmic domain. IL-1 RII does not appear to signal in response to IL-1 and may function as a decoy receptor that attenuates IL-1 function (19). The IL-1 receptor accessory protein (IL-1 RAcP) associates with IL-1 RI and is required for IL-1 RI signal transduction (20). IL-1ra is a secreted molecule that functions as a competitive inhibitor of IL-1 (21, 22). Soluble forms of both IL-1 RI and IL-1 RII have been detected in human plasma, synovial fluids, and the conditioned media of several human cell lines (23, 24). In addition, IL-1 binding proteins that resemble soluble IL-1 RII are encoded by vaccinia and cowpox viruses (25).

Long Name:
Interleukin 1 beta
Entrez Gene IDs:
3553 (Human); 16176 (Mouse); 24494 (Rat); 397122 (Porcine); 403974 (Canine); 100034237 (Equine); 100135556 (Guinea Pig)
Alternate Names:
catabolin; IL1 beta; IL-1 beta; IL-1; IL1B; IL-1b; IL1-BETA; IL-1F2; IL1F2IL-1 beta; interleukin 1, beta; interleukin-1 beta; preinterleukin 1 beta; pro-interleukin-1-beta
⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Citations for Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

284 Citations: Showing 1 - 10
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  1. Macrophage MSR1 promotes the formation of foamy macrophage and neuronal apoptosis after spinal cord injury
    Authors: FQ Kong, SJ Zhao, P Sun, H Liu, J Jie, T Xu, AD Xu, YQ Yang, Y Zhu, J Chen, Z Zhou, DF Qian, CJ Gu, Q Chen, GY Yin, HW Zhang, J Fan
    J Neuroinflammation, 2020;17(1):62.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  2. Effect of HBx on inflammation and mitochondrial oxidative stress in mouse hepatocytes
    Authors: LR Ling, DH Zheng, ZY Zhang, WH Xie, YH Huang, ZX Chen, XZ Wang, D Li
    Oncol Lett, 2020;19(4):2861-2869.
  3. Nrf2 deficiency aggravates PM2.5-induced cardiomyopathy by enhancing oxidative stress, fibrosis and inflammation via RIPK3-regulated mitochondrial disorder
    Authors: C Ge, L Hu, D Lou, Q Li, J Feng, Y Wu, J Tan, M Xu
    Aging (Albany NY), 2020;12(6):4836-4865.
    Species: Mouse
    Sample Types: Serum
  4. Carnosol inhibits inflammasome activation by directly targeting HSP90 to treat inflammasome-mediated diseases
    Authors: W Shi, G Xu, X Zhan, Y Gao, Z Wang, S Fu, N Qin, X Hou, Y Ai, C Wang, T He, H Liu, Y Chen, Y Liu, J Wang, M Niu, Y Guo, X Xiao, Z Bai
    Cell Death Dis, 2020;11(4):252.
    Species: Mouse
    Sample Types: Serum
  5. The Set7 Lysine Methyltransferase Regulates Plasticity in Oxidative Phosphorylation Necessary for Trained Immunity Induced by &beta-Glucan
    Authors: ST Keating, L Groh, CDCC van der He, H Rodriguez, JC Dos Santos, S Fanucchi, J Okabe, H Kaipananic, JH van Puffel, L Helder, MP Noz, V Matzaraki, Y Li, LCJ de Bree, VACM Koeken, SJCFM Moorlag, VP Mourits, J Domínguez-, M Oosting, EP Bulthuis, WJH Koopman, M Mhlanga, A El-Osta, LAB Joosten, MG Netea, NP Riksen
    Cell Rep, 2020;31(3):107548.
    Species: Mouse
    Sample Types: Plasma
  6. Roseburia�intestinalis?derived flagellin ameliorates colitis by targeting miR?223?3p?mediated activation of NLRP3 inflammasome and pyroptosis
    Authors: X Wu, S Pan, W Luo, Z Shen, X Meng, M Xiao, B Tan, K Nie, T Tong, X Wang
    Mol Med Rep, 2020;0(0):.
    Species: Mouse
    Sample Types: Serum
  7. Nintedanib Reduces Neutrophil Chemotaxis via Activating GRK2 in Bleomycin-Induced Pulmonary Fibrosis
    Authors: WC Chen, NJ Chen, HP Chen, WK Yu, VY Su, H Chen, HH Wu, KY Yang
    Int J Mol Sci, 2020;21(13):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  8. Fisetin alleviates sepsis-induced multiple organ dysfunction in mice via inhibiting p38 MAPK/MK2 signaling
    Authors: HF Zhang, HB Zhang, XP Wu, YL Guo, WD Cheng, F Qian
    Acta Pharmacol. Sin., 2020;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  9. Maternal high-fat diet exaggerates diet-induced insulin resistance in adult offspring by enhancing inflammasome activation through noncanonical pathway of caspase-11
    Authors: N Wada, H Yamada, S Motoyama, M Saburi, T Sugimoto, H Kubota, D Miyawaki, N Wakana, D Kami, T Ogata, S Matoba
    Mol Metab, 2020;37(0):100988.
    Species: Mouse
    Sample Types: Serum
  10. Attenuation of noisy environment-induced neuroinflammation and dysfunction of learning and memory by minocycline during perioperative period in mice
    Authors: F Lin, Y Zheng, L Pan, Z Zuo
    Brain Res. Bull., 2020;159(0):16-24.
    Species: Mouse
    Sample Types: Tissue Homogenates
  11. Through Reducing ROS Production, IL-10 Suppresses Caspase-1-Dependent IL-1&beta Maturation, thereby Preventing Chronic Neuroinflammation and Neurodegeneration
    Authors: Y Gao, D Tu, R Yang, CH Chu, JS Hong, HM Gao
    Int J Mol Sci, 2020;21(2):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  12. Benzydamine inhibits osteoclast differentiation and bone resorption via down-regulation of interleukin-1 &beta expression
    Authors: HS Son, J Lee, HI Lee, N Kim, YJ Jo, GR Lee, SE Hong, M Kwon, NY Kim, HJ Kim, JH Park, SY Lee, W Jeong
    Acta Pharm Sin B, 2020;10(3):462-474.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  13. Nucleic Acid-Sensing Toll-Like Receptors Play a Dominant Role in Innate Immune Recognition of Pneumococci
    Authors: A Famà, A Midiri, G Mancuso, C Biondo, G Lentini, R Galbo, MM Giardina, GV De Gaetano, L Romeo, G Teti, C Beninati
    MBio, 2020;11(2):.
    Species: Mouse
    Sample Types: Tissue Lysates
  14. Activation of ASC Inflammasome Driven by TLR4 Contributes to Host Immunity against Rickettsial Infection
    Authors: C Rumfield, I Hyseni, JW McBride, DH Walker, R Fang
    Infect. Immun., 2020;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  15. Hydrogen Sulfide Attenuates Particulate Matter-Induced Emphysema and Airway Inflammation Through Nrf2-Dependent Manner
    Authors: G Jia, S Yu, W Sun, J Yang, Y Wang, Y Qi, Y Chen
    Front Pharmacol, 2020;11(0):29.
    Species: Mouse
    Sample Types: BALF
  16. Avicularin Relieves Depressive-Like Behaviors Induced by Chronic Unpredictable Mild Stress in Mice
    Authors: Z Shen, Y Xu, X Jiang, Z Wang, Y Guo, W Pan, J Hou
    Med. Sci. Monit., 2019;25(0):2777-2784.
    Species: Mouse
    Sample Types: Tissue Homogenates
  17. Immunomodulatory effect of mancozeb, chlorothalonil, and thiophanate methyl pesticides on macrophage cells
    Authors: GCC Weis, CE Assmann, FC Cadoná, BDSR Bonadiman, AO Alves, AK Machado, MMMF Duarte, IBM da Cruz, IH Costabeber
    Ecotoxicol. Environ. Saf., 2019;182(0):109420.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  18. Nephropathy in Hypertensive Animals Is Linked to M2 Macrophages and Increased Expression of the YM1/Chi3l3 Protein
    Authors: PAM Cavalcante, N Alenina, A Budu, LC Freitas-Li, T Alves-Silv, JSH Agudelo, F Qadri, NOS Camara, M Bader, RC Araújo
    Mediators Inflamm., 2019;2019(0):9086758.
    Species: Mouse
    Sample Types: Tissue Lysates
  19. Carnosic acid alleviates brain injury through NF?κB?regulated inflammation and Caspase?3?associated apoptosis in high fat?induced mouse models
    Authors: Y Liu, Y Zhang, M Hu, YH Li, XH Cao
    Mol Med Rep, 2019;20(1):495-504.
    Species: Mouse
    Sample Types: Serum
  20. Macrophage migration inhibitory factor enhances influenza-associated mortality in mice
    Authors: CA Smith, DJ Tyrell, UA Kulkarni, S Wood, L Leng, RL Zemans, R Bucala, DR Goldstein
    JCI Insight, 2019;4(13):.
    Species: Mouse
    Sample Types: BALF
  21. Control of TLR7-mediated type I IFN signaling in pDCs through CXCR4 engagement-A new target for lupus treatment
    Authors: N Smith, MP Rodero, N Bekaddour, V Bondet, YB Ruiz-Blanc, M Harms, B Mayer, B Badder-Meu, P Quartier, C Bodemer, V Baudouin, Y Dieudonné, F Kirchhoff, E Sanchez Ga, B Charbit, N Leboulange, B Jahrsdörfe, Y Richard, AS Korganow, J Münch, S Nisole, D Duffy, JP Herbeuval
    Sci Adv, 2019;5(7):eaav9019.
    Species: Mouse
    Sample Types: Serum
  22. Liver-target nanotechnology facilitates berberine to ameliorate cardio-metabolic diseases
    Authors: HH Guo, CL Feng, WX Zhang, ZG Luo, HJ Zhang, TT Zhang, C Ma, Y Zhan, R Li, S Wu, Z Abliz, C Li, XL Li, XL Ma, LL Wang, WS Zheng, YX Han, JD Jiang
    Nat Commun, 2019;10(1):1981.
    Species: Mouse
    Sample Types: Plasma
  23. Melatonin Inhibits Lipopolysaccharide-Induced Inflammation and Oxidative Stress in Cultured Mouse Mammary Tissue
    Authors: GM Yu, W Tan
    Mediators Inflamm., 2019;2019(0):8597159.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  24. Adipocyte-secreted exosomal microRNA-34a inhibits M2 macrophage polarization to promote obesity-induced adipose inflammation
    Authors: Y Pan, X Hui, RLC Hoo, D Ye, CYC Chan, T Feng, Y Wang, KSL Lam, A Xu
    J. Clin. Invest., 2019;129(2):834-849.
    Species: Mouse
    Sample Types: Serum
  25. The macrophage-specific V-ATPase subunit ATP6V0D2 restricts inflammasome activation and bacterial infection by facilitating autophagosome-lysosome fusion
    Authors: Y Xia, N Liu, X Xie, G Bi, H Ba, L Li, J Zhang, X Deng, Y Yao, Z Tang, B Yin, J Wang, K Jiang, Z Li, Y Choi, F Gong, X Cheng, JJ O'Shea, JJ Chae, A Laurence, XP Yang
    Autophagy, 2019;0(0):1-16.
    Species: Mouse
    Sample Types: Serum
  26. Modulation of Gut Microbiota Composition by Serotonin Signaling Influences Intestinal Immune Response and Susceptibility to Colitis
    Authors: YH Kwon, H Wang, E Denou, JE Ghia, L Rossi, ME Fontes, SP Bernier, MS Shajib, S Banskota, SM Collins, MG Surette, WI Khan
    Cell Mol Gastroenterol Hepatol, 2019;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  27. Costunolide alleviates HKSA-induced acute lung injury via inhibition of macrophage activation
    Authors: YT Chen, Y Du, B Zhao, LX Gan, KK Yu, L Sun, J Wang, F Qian
    Acta Pharmacol. Sin., 2019;0(0):.
    Species: Mouse
    Sample Types: BALF
  28. Induced Pluripotent Stem Cells Regulate TREM-1 Expression and the p38 MAPK Pathway in Endotoxin-Induced Acute Lung Injury
    Authors: VY Su, KY Yang, SH Chiou, NJ Chen, MH Mo, CS Lin, CT Wang
    Stem Cells, 2019;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  29. Lack of whey acidic protein four disulphide core (WFDC) 2 protease inhibitor causes neonatal death from respiratory failure in mice
    Authors: K Nakajima, M Ono, U Radovi?, S Dizdarevi?, SI Tomizawa, K Kuroha, G Naganatsu, I Hoshi, R Matsunaga, T Shirakawa, T Kurosawa, Y Miyazaki, M Seki, Y Suzuki, H Koseki, M Nakamura, T Suda, K Ohbo
    Dis Model Mech, 2019;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  30. The activation of retinal HCA2 receptors by systemic beta-hydroxybutyrate inhibits diabetic retinal damage through reduction of endoplasmic reticulum stress and the NLRP3 inflammasome
    Authors: MC Trotta, R Maisto, F Guida, S Boccella, L Luongo, C Balta, G D'Amico, H Herman, A Hermenean, C Bucolo, M D'Amico
    PLoS ONE, 2019;14(1):e0211005.
    Species: Mouse
    Sample Types: Serum
  31. Fucoxanthin, a Marine Xanthophyll Isolated From Conticribra weissflogii ND-8: Preventive Anti-Inflammatory Effect in a Mouse Model of Sepsis
    Authors: J Su, K Guo, M Huang, Y Liu, J Zhang, L Sun, D Li, KL Pang, G Wang, L Chen, Z Liu, Y Chen, Q Chen, L Huang
    Front Pharmacol, 2019;10(0):906.
    Species: Mouse
    Sample Types: Serum
  32. cAMP metabolism controls caspase-11 inflammasome activation and pyroptosis in sepsis
    Authors: R Chen, L Zeng, S Zhu, J Liu, HJ Zeh, G Kroemer, H Wang, TR Billiar, J Jiang, D Tang, R Kang
    Sci Adv, 2019;5(5):eaav5562.
    Species: Mouse
    Sample Types: Serum
  33. Acute transient cognitive dysfunction and acute brain injury induced by systemic inflammation occur by dissociable IL-1-dependent mechanisms
    Authors: DT Skelly, ÉW Griffin, CL Murray, S Harney, C O'Boyle, E Hennessy, MA Dansereau, A Nazmi, L Tortorelli, JN Rawlins, DM Bannerman, C Cunningham
    Mol. Psychiatry, 2019;24(10):1533-1548.
    Species: Mouse
    Sample Types: Plasma
  34. Oral flavonoid fisetin treatment protects against prolonged high-fat-diet-induced cardiac dysfunction by regulation of multicombined signaling
    Authors: LF Hu, J Feng, X Dai, Y Sun, M Xiong, L Lai, S Zhong, C Yi, G Chen, H Li, Q Yang, Q Kuang, T Long, J Zhan, T Tang, C Ge, J Tan, M Xu
    J. Nutr. Biochem., 2019;77(0):108253.
    Species: Mouse
    Sample Types: Serum
  35. Gestational oxidative stress protects against adult obesity and insulin resistance
    Authors: LG Dimova, S Battista, T Plösch, RA Kampen, F Liu, RN Verkaik-Sc, D Pratico, HJ Verkade, UJF Tietge
    Redox Biol, 2019;28(0):101329.
    Species: Mouse
    Sample Types: Plasma
  36. Downregulation of RalGTPase-activating protein promotes colitis-associated cancer via NLRP3 inflammasome activation
    Authors: T Iida, Daisuke Hi, N Minami, M Matsuura, K Wagatsuma, K Kawakami, K Nagaishi, M Nojima, H Ikeuchi, S Hirota, R Shirakawa, H Horiuchi, H Nakase
    Cell Mol Gastroenterol Hepatol, 2019;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  37. CCL28 promotes locomotor recovery after spinal cord injury via recruiting regulatory T cells
    Authors: P Wang, X Qi, G Xu, J Liu, J Guo, X Li, X Ma, H Sun
    Aging (Albany NY), 2019;11(18):7402-7415.
    Species: Mouse
    Sample Types: Tissue Homogenates
  38. Autophagy regulates the therapeutic potential of adipose-derived stem cells in LPS-induced pulmonary microvascular barrier damage
    Authors: C Li, J Pan, L Ye, H Xu, B Wang, H Xu, L Xu, T Hou, D Zhang
    Cell Death Dis, 2019;10(11):804.
    Species: Mouse
    Sample Types: BALF
  39. Notoginsenoside R1 suppresses miR-301a via NF-kappaB pathway in lipopolysaccharide-treated ATDC5 cells
    Authors: Y Dong, X Yan, X Yang, C Yu, Y Deng, X Song, L Zhang
    Exp. Mol. Pathol., 2019;112(0):104355.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  40. A truncating mutation in the autophagy gene UVRAG drives inflammation and tumorigenesis in mice
    Authors: C Quach, Y Song, H Guo, S Li, H Maazi, M Fung, N Sands, D O'Connell, S Restrepo-V, B Chai, D Nemecio, V Punj, O Akbari, GE Idos, SM Mumenthale, N Wu, SE Martin, A Hagiya, J Hicks, H Cui, C Liang
    Nat Commun, 2019;10(1):5681.
    Species: Mouse
    Sample Types: Serum
  41. Carnosic acid alleviates brain injury through NF?κB?regulated inflammation and Caspase?3?associated apoptosis in high fat?induced mouse models
    Authors: Y Liu, Y Zhang, M Hu, YH Li, XH Cao
    Mol Med Rep, 2019;20(1):495-504.
    Species: Mouse
    Sample Types: Serum
  42. Increased Soluble Epoxide Hydrolase in Human Gestational Tissues from Pregnancies Complicated by Acute Chorioamnionitis
    Authors: TH Hung, SF Chen, CH Wu, CC Kao, CP Wu
    Mediators Inflamm., 2019;2019(0):8687120.
    Species: Mouse
    Sample Types: Tissue Homogenates
  43. NLRP3 inflammasome in fibroblasts links tissue damage with inflammation in breast cancer progression and metastasis
    Authors: N Ershaid, Y Sharon, H Doron, Y Raz, O Shani, N Cohen, L Monteran, L Leider-Tre, A Ben-Shmuel, M Yassin, M Gerlic, A Ben-Baruch, M Pasmanik-C, R Apte, N Erez
    Nat Commun, 2019;10(1):4375.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  44. The Additive Effects of Low Dose Intake of Ferulic Acid, Phosphatidylserine and Curcumin, Not Alone, Improve Cognitive Function in APPswe/PS1dE9 Transgenic Mice
    Authors: M Okuda, Y Fujita, H Sugimoto
    Biol. Pharm. Bull., 2019;42(10):1694-1706.
    Species: Mouse
    Sample Types: Tissue Homogenates
  45. Antenatal IL-1-dependent inflammation persists postnatally and causes retinal and sub-retinal vasculopathy in progeny
    Authors: A Beaudry-Ri, M Nadeau-Val, É Prairie, N Maurice, É Heckel, M Nezhady, S Pundir, A Madaan, A Boudreault, X Hou, C Quiniou, EM Sierra, A Beaulac, G Lodygensky, SA Robertson, J Keelan, K Adams-Wald, DM Olson, JC Rivera, WD Lubell, JS Joyal, JF Bouchard, S Chemtob
    Sci Rep, 2018;8(1):11875.
    Species: Mouse
    Sample Types: Tissue Homogenates
  46. Complement activation contributes to perioperative neurocognitive disorders in mice
    Authors: C Xiong, J Liu, D Lin, J Zhang, N Terrando, A Wu
    J Neuroinflammation, 2018;15(1):254.
    Species: Mouse
    Sample Types: Tissue Homogenates
  47. Mitochondrial dysfunction induces NLRP3 inflammasome activation during cerebral ischemia/reperfusion injury
    Authors: Z Gong, J Pan, Q Shen, M Li, Y Peng
    J Neuroinflammation, 2018;15(1):242.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  48. Activation of Bone Marrow-Derived Cells Angiotensin (Ang) II Type 1 Receptor by Ang II Promotes Atherosclerotic Plaque Vulnerability
    Authors: M Pellegrin, K Bouzourène, JF Aubert, A Nahimana, MA Duchosal, L Mazzolai
    Int J Mol Sci, 2018;19(9):.
    Species: Mouse
    Sample Types: Plasma
  49. Regulation of the NLRP3 inflammasome and macrophage pyroptosis by the p38 MAPK signaling pathway in a mouse model of acute lung injury
    Authors: D Li, W Ren, Z Jiang, L Zhu
    Mol Med Rep, 2018;0(0):.
    Species: Mouse
    Sample Types: BALF
  50. GPR37 regulates macrophage phagocytosis and resolution of inflammatory pain
    Authors: S Bang, YK Xie, ZJ Zhang, Z Wang, ZZ Xu, RR Ji
    J. Clin. Invest., 2018;128(8):3568-3582.
    Species: Mouse
    Sample Types: Tissue Homogenates
  51. Perioperative use of cefazolin ameliorates postoperative cognitive dysfunction but induces gut inflammation in mice
    Authors: P Liang, W Shan, Z Zuo
    J Neuroinflammation, 2018;15(1):235.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  52. The anticancer peptide RT53 induces immunogenic cell death
    Authors: E Pasquereau, J Habault, G Kroemer, JL Poyet
    PLoS ONE, 2018;13(8):e0201220.
    Species: Mouse
    Sample Types: Serum
  53. Interleukin-1 receptor antagonist-mediated neuroprotection by umbilical cord-derived mesenchymal stromal cells following transplantation into a rodent stroke model
    Authors: SH Oh, C Choi, JE Noh, N Lee, YW Jeong, I Jeon, JM Shin, JH Kim, HJ Kim, JM Lee, HS Kim, OJ Kim, J Song
    Exp. Mol. Med., 2018;50(4):22.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  54. Macrophage-derived IL-1?/NF-?B signaling mediates parenteral nutrition-associated cholestasis
    Authors: KC El Kasmi, PM Vue, AL Anderson, MW Devereaux, S Ghosh, N Balasubram, SA Fillon, C Dahrenmoel, A Allawzi, C Woods, S McKenna, CJ Wright, L Johnson, A D'Alessand, JA Reisz, E Nozik-Gray, FJ Suchy, RJ Sokol
    Nat Commun, 2018;9(1):1393.
    Species: Mouse
    Sample Types: Serum
  55. CR6 interacting factor 1 deficiency promotes endothelial inflammation by SIRT1 downregulation
    Authors: S Piao, JW Lee, H Nagar, SB Jung, S Choi, S Kim, I Lee, SM Kim, N Shin, YR Lee, SD Lee, JB Park, K Irani, M Won, GM Hur, BH Jeon, DW Kim, CS Kim
    PLoS ONE, 2018;13(2):e0192693.
    Species: Mouse
    Sample Types: Plasma
  56. The NLRP3 Inflammasome May Contribute to Pathologic Neovascularization in the Advanced Stages of Diabetic Retinopathy
    Authors: SS Chaurasia, RR Lim, BH Parikh, YS Wey, BB Tun, TY Wong, CD Luu, R Agrawal, A Ghosh, A Mortellaro, E Rackoczy, RR Mohan, VA Barathi
    Sci Rep, 2018;8(1):2847.
    Species: Mouse
    Sample Types: Tissue Homogenates
  57. An unexpected link between fatty acid synthase and cholesterol synthesis in proinflammatory macrophage activation
    Authors: RG Carroll, Z Zas?ona, S Galván-Peñ, EL Koppe, DC Sévin, S Angiari, M Triantafil, K Triantafil, LK Modis, LA O'Neill
    J. Biol. Chem., 2018;293(15):5509-5521.
    Species: Mouse
    Sample Types: Serum
  58. MTOR Suppresses Environmental Particle-Induced Inflammatory Response in Macrophages
    Authors: Z Li, Y Wu, H Chen, C Zhu, L Dong, Y Wang, H Liu, X Xu, J Zhou, Y Wu, W Li, S Ying, H Shen, Z Chen
    J. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types: BALF
  59. Crude extract and fractions from Eugenia uniflora Linn leaves showed anti-inflammatory, antioxidant, and antibacterial activities
    Authors: TR Falcão, AA de Araújo, LAL Soares, RT de Moraes, ICF Bezerra, MRA Ferreira, MA de Souza N, MCN Melo, RF de Araújo, ACV de Aguiar, JS de Medeiro, GCB Guerra
    BMC Complement Altern Med, 2018;18(1):84.
    Species: Mouse
    Sample Types: Peritoneal Fluid
  60. Protective effects of Erigeron breviscapus Hand.- Mazz. (EBHM) extract in retinal neurodegeneration models
    Authors: J Zhu, L Chen, Y Qi, J Feng, L Zhu, Y Bai, H Wu
    Mol. Vis., 2018;24(0):315-325.
    Species: Rat
    Sample Types: Cell Culture Supernates
  61. Myeloid p38? signaling promotes intestinal IGF-1 production and inflammation-associated tumorigenesis
    Authors: C Youssif, M Cubillos-R, M Comalada, E Llonch, C Perna, N Djouder, AR Nebreda
    EMBO Mol Med, 2018;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  62. Xanthohumol prevents dextran sulfate sodium-induced colitis via inhibition of IKK?/NF-?B signaling in mice
    Authors: JM Cho, SM Yun, YH Choi, J Heo, NJ Kim, SH Kim, EH Kim
    Oncotarget, 2018;9(1):866-880.
    Species: Mouse
    Sample Types: Serum
  63. JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents depression-associated behaviors induced by chronic social defeat stress
    Authors: X Zhu, MT Nedelcovyc, AG Thomas, Y Hasegawa, A Moreno-Meg, W Coomer, V Vohra, A Saito, G Perez, Y Wu, J Alt, E Prchalova, L Tenora, P Majer, R Rais, C Rojas, BS Slusher, A Kamiya
    Neuropsychopharmacology, 2018;0(0):.
    Species: Mouse
    Sample Types: Serum
  64. ?-Synuclein disrupts the anti-inflammatory role of Drd2 via interfering ?-arrestin2-TAB1 interaction in astrocytes
    Authors: RH Du, Y Zhou, ML Xia, M Lu, JH Ding, G Hu
    J Neuroinflammation, 2018;15(1):258.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  65. A Novel Peroxidase Mimics and Ameliorates Alzheimer's Disease-Related Pathology and Cognitive Decline in Mice
    Authors: J Xu, K Wang, Y Yuan, H Li, R Zhang, S Guan, L Wang
    Int J Mol Sci, 2018;19(11):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  66. An insight into the role of magnesium in the immunomodulatory properties of mesenchymal stem cells
    Authors: F da Silva L, AB da Rocha R, A Hastreiter, A Nogueira-P, E Makiyama, C Colli, RA Fock
    J. Nutr. Biochem., 2018;55(0):200-208.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  67. Juglanin suppresses fibrosis and inflammation response caused by LPS in acute lung injury
    Authors: ZW Dong, YF Yuan
    Int. J. Mol. Med., 2018;41(6):3353-3365.
    Species: Mouse
    Sample Types: Serum
  68. Carnosic acid protects mice from high-fat diet-induced NAFLD by regulating MARCKS
    Authors: HM Song, X Li, YY Liu, WP Lu, ZH Cui, L Zhou, D Yao, HM Zhang
    Int. J. Mol. Med., 2018;0(0):.
    Species: Mouse
    Sample Types: Serum
  69. Effect of internal contamination with tritiated water on the neoplastic colonies in the lungs, innate anti-tumour reactions, cytokine profile, and haematopoietic system in radioresistant and radiosensitive mice
    Authors: EM Nowosielsk, A Cheda, R Zdanowski, S Lewicki, BR Scott, MK Janiak
    Radiat Environ Biophys, 2018;0(0):.
    Species: Mouse
    Sample Types: Serum
  70. Chemopreventive Effect of Aster glehni on Inflammation-Induced Colorectal Carcinogenesis in Mice
    Authors: KS Chung, SY Cheon, SS Roh, M Lee, HJ An
    Nutrients, 2018;10(2):.
    Species: Mouse
    Sample Types: Tissue Culture Supernates
    Applications: ELISA Capture
  71. SARM1 deletion restrains NAFLD induced by high fat diet (HFD) through reducing inflammation, oxidative stress and lipid accumulation
    Authors: ZG Pan, XS An
    Biochem. Biophys. Res. Commun., 2018;0(0):.
    Species: Mouse
    Sample Types: Serum
    Applications: ELISA Capture
  72. SIRT3 deficiency-induced mitochondrial dysfunction and inflammasome formation in the brain
    Authors: A Tyagi, CU Nguyen, T Chong, CR Michel, KS Fritz, N Reisdorph, L Knaub, JEB Reusch, S Pugazhenth
    Sci Rep, 2018;8(1):17547.
    Species: Mouse
    Sample Types: Plasma
  73. Inhibition of MicroRNA-23b Attenuates Immunosuppression in Late Sepsis through NIK, TRAF1 and XIAP
    Authors: H Zhang, H Li, A Shaikh, Y Caudle, B Yao, D Yin
    J. Infect. Dis., 2018;0(0):.
    Species: Mouse
    Sample Types: Serum
  74. REDD-1 aggravates endotoxin-induced inflammation via atypical NF-?B activation
    Authors: DK Lee, JH Kim, J Kim, S Choi, M Park, W Park, S Kim, KS Lee, T Kim, J Jung, YK Choi, KS Ha, MH Won, TR Billiar, YG Kwon, YM Kim
    FASEB J., 2018;0(0):fj201701436R.
    Species: Mouse
    Sample Types: Serum
  75. Immunization with Pseudomonas aeruginosa outer membrane vesicles stimulates protective immunity in mice
    Authors: X Zhang, F Yang, J Zou, W Wu, H Jing, Q Gou, H Li, J Gu, Q Zou, J Zhang
    Vaccine, 2018;36(8):1047-1054.
    Species: Mouse
    Sample Types: Cell Culture Supernates
    Applications: ELISA Capture
  76. Accelerated inflammation and oxidative stress induced by LPS in acute lung injury: ?nhibition by ST1926
    Authors: Z Dong, Y Yuan
    Int. J. Mol. Med., 2018;0(0):.
    Species: Mouse
    Sample Types: Serum
  77. Oleanolic acid acetate attenuates polyhexamethylene guanidine phosphate-induced pulmonary inflammation and fibrosis in mice
    Authors: MS Kim, JY Han, SH Kim, D Jeon, HY Kim, SW Lee, MC Rho, K Lee
    Respir Physiol Neurobiol, 2018;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  78. TRAF3-interacting JNK-activating modulator promotes inflammation by stimulating� translocation of Toll-like receptor 4 to lipid rafts
    Authors: Y Li, J Guan, W Wang, C Hou, L Zhou, J Ma, Y Cheng, S Jiao, Z Zhou
    J. Biol. Chem., 2018;0(0):.
    Species: Mouse
    Sample Types: Serum
  79. Fibronectin Containing Extra Domain A Induces Plaque Destabilization in the Innominate Artery of Aged Apolipoprotein E-Deficient Mice
    Authors: P Doddapatta, M Jain, N Dhanesha, SR Lentz, AK Chauhan
    Arterioscler. Thromb. Vasc. Biol., 2018;0(0):.
    Species: Mouse
    Sample Types: Plasma
  80. Pharmacological stimulation of NQO1 decreases NADPH levels and ameliorates acute pancreatitis in mice
    Authors: A Shen, HJ Kim, GS Oh, SB Lee, S Lee, A Pandit, D Khadka, S Sharma, SY Kim, SK Choe, SH Yang, EY Cho, H Shim, R Park, TH Kwak, HS So
    Cell Death Dis, 2018;10(1):5.
    Species: Mouse
    Sample Types: Serum
  81. Protective Effects of Nintedanib against Polyhexamethylene Guanidine Phosphate-Induced Lung Fibrosis in Mice
    Authors: HY Kim, MS Kim, SH Kim, D Joen, K Lee
    Molecules, 2018;23(8):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  82. LncRNA GAS5 Overexpression Reverses LPS-Induced Inflammatory Injury and Apoptosis Through Up-Regulating KLF2 Expression in ATDC5 Chondrocytes
    Authors: F Li, J Sun, S Huang, G Su, G Pi
    Cell. Physiol. Biochem., 2018;45(3):1241-1251.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  83. Succinate and its G-protein-coupled receptor stimulates osteoclastogenesis
    Authors: Y Guo, C Xie, X Li, J Yang, T Yu, R Zhang, T Zhang, D Saxena, M Snyder, Y Wu, X Li
    Nat Commun, 2017;8(0):15621.
    Species: Mouse
    Sample Types: Serum
    Applications: data reported
  84. Interference of the T Cell and Antigen-Presenting Cell Costimulatory Pathway Using CTLA4-Ig (Abatacept) Prevents Staphylococcal Enterotoxin B Pathology
    Authors: SJ Whitfield, C Taylor, JE Risdall, GD Griffiths, JT Jones, ED Williamson, S Rijpkema, L Saraiva, S Vessillier, AC Green, AJ Carter
    J. Immunol, 2017;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  85. Protective Efficacy of the Trivalent Pseudomonas aeruginosa Vaccine Candidate PcrV-OprI-Hcp1 in Murine Pneumonia and Burn Models
    Authors: F Yang, J Gu, L Yang, C Gao, H Jing, Y Wang, H Zeng, Q Zou, F Lv, J Zhang
    Sci Rep, 2017;7(1):3957.
    Species: Mouse
    Sample Types: BALF
  86. Mitochondrial DNA-enriched microparticles promote acute-on-chronic alcoholic neutrophilia and hepatotoxicity
    Authors: Y Cai, MJ Xu, EH Koritzinsk, Z Zhou, W Wang, H Cao, PS Yuen, RA Ross, RA Star, S Liangpunsa, B Gao
    JCI Insight, 2017;2(14):.
    Species: Mouse
    Sample Types: Serum
  87. Cthrc1 lowers pulmonary collagen associated with bleomycin-induced fibrosis and protects lung function
    Authors: AP Binks, M Beyer, R Miller, RJ LeClair
    Physiol Rep, 2017;5(5):.
    Species: Mouse
    Sample Types: BALF
  88. Regulation of Arthritis Severity by the Acid Sphingomyelinase
    Authors: N Beckmann, KA Becker, S Walter, JU Becker, M Kramer, G Hessler, S Weber, JR Göthert, K Fassbender, E Gulbins, A Carpinteir
    Cell. Physiol. Biochem., 2017;43(4):1.
    Species: Mouse
    Sample Types: Tissue Homogenates
  89. Oleocanthal-rich extra-virgin olive oil enhances donepezil effect by reducing amyloid-? load and related toxicity in a mouse model of Alzheimer's disease
    Authors: YS Batarseh, A Kaddoumi
    J. Nutr. Biochem., 2017;55(0):113-123.
    Species: Mouse
    Sample Types: Tissue Homogenates
  90. Calf Spleen Extractive Injection protects mice against cyclophosphamide-induced hematopoietic injury through G-CSF-mediated JAK2/STAT3 signaling
    Authors: W Lu, D Jia, S An, M Mu, X Qiao, Y Liu, X Li, D Wang
    Sci Rep, 2017;7(1):8402.
    Species: Mouse
    Sample Types: Plasma
  91. Effects of polysaccharide fractions isolated from Caltha palustris L. on the activity of phagocytic cells & humoral immune response in mice with collagen-induced arthritis: A comparison with methotrexate
    Authors: A Suszko, B Obmi?ska-M
    Indian J. Med. Res., 2017;145(2):229-236.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  92. NAD(+) augmentation ameliorates acute pancreatitis through regulation of inflammasome signalling
    Authors: A Shen, HJ Kim, GS Oh, SB Lee, SH Lee, A Pandit, D Khadka, SK Choe, SC Kwak, SH Yang, EY Cho, HS Kim, H Kim, R Park, TH Kwak, HS So
    Sci Rep, 2017;7(1):3006.
    Species: Mouse
    Sample Types: Serum
  93. Acute fasting inhibits central caspase-1 activity reducing anxiety-like behavior and increasing novel object and object location recognition
    Authors: AE Towers, ML Oelschlage, J Patel, SJ Gainey, RH McCusker, GG Freund
    Metab. Clin. Exp., 2017;71(0):70-82.
    Species: Mouse
    Sample Types: Tissue Homogenates
  94. Specific calpain inhibition protects kidney against inflammaging
    Authors: G Hanouna, L Mesnard, S Vandermeer, J Perez, S Placier, JP Haymann, F Campagne, J Moroch, A Bataille, L Baud, E Letavernie
    Sci Rep, 2017;7(1):8016.
    Species: Mouse
    Sample Types: Peritoneal Fluid
  95. Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy
    Authors: EE To, R Vlahos, R Luong, ML Halls, PC Reading, PT King, C Chan, GR Drummond, CG Sobey, BRS Broughton, MR Starkey, R van der Sl, SR Lewin, S Bozinovski, LAJ O'Neill, T Quach, CJH Porter, DA Brooks, JJ O'Leary, S Selemidis
    Nat Commun, 2017;8(1):69.
    Species: Mouse
    Sample Types: BALF
  96. Interleukin-1 receptor in seizure susceptibility after traumatic injury to the pediatric brain
    Authors: BD Semple, TJ O'Brien, K Gimlin, DK Wright, S Eun Kim, PM Casillas-E, KM Webster, S Petrou, LJ Noble-Haeu
    J. Neurosci., 2017;0(0):.
    Species: Mouse
    Sample Types: Serum
  97. STAT1 Represses Cytokine-Producing Group 2 and Group 3 Innate Lymphoid Cells during Viral Infection
    Authors: MT Stier, K Goleniewsk, JY Cephus, DC Newcomb, TP Sherrill, KL Boyd, MH Bloodworth, ML Moore, K Chen, JK Kolls, RS Peebles
    J. Immunol., 2017;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  98. Circulating soluble endoglin modifies the inflammatory response in mice
    Authors: L Ruiz-Remol, C Ollauri-Ib, L Pérez-Roqu, E Núñez-Góme, F Pérez-Barr, JM López-Novo, M Pericacho, A Rodríguez-
    PLoS ONE, 2017;12(11):e0188204.
    Species: Mouse
    Sample Types: Plasma
  99. P2X7 receptor antagonism prevents IL-1? release from salivary epithelial cells and reduces inflammation in a mouse model of autoimmune exocrinopathy
    Authors: MG Khalafalla, LT Woods, JM Camden, AA Khan, KH Limesand, MJ Petris, L Erb, GA Weisman
    J. Biol. Chem., 2017;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  100. Xenotransplantation of layer-by-layer encapsulated non-human primate islets with a specified immunosuppressive drug protocol
    Authors: MR Haque, J Kim, H Park, HS Lee, KW Lee, TA Al-Hilal, JH Jeong, CH Ahn, DS Lee, SJ Kim, Y Byun
    J Control Release, 2017;0(0):.
    Species: Mouse
    Sample Types: Serum
  101. Lentinan from shiitake selectively attenuates AIM2 and non-canonical inflammasome activation while inducing pro-inflammatory cytokine production
    Authors: H Ahn, E Jeon, JC Kim, SG Kang, SI Yoon, HJ Ko, PH Kim, GS Lee
    Sci Rep, 2017;7(1):1314.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  102. Chronic intermittent hypoxia induces liver fibrosis in mice with diet-induced obesity via TLR4/MyD88/MAPK/NF-kB signaling pathways
    Authors: HH Kang, IK Kim, HI Lee, H Joo, JU Lim, J Lee, SH Lee, HS Moon
    Biochem. Biophys. Res. Commun., 2017;0(0):.
    Species: Mouse
    Sample Types: Serum
  103. Alleviation of secondary brain injury, posttraumatic inflammation, and brain edema formation by inhibition of factor XIIa
    Authors: S Hopp, MW Nolte, C Stetter, C Kleinschni, AL Sirén, C Albert-Wei
    J Neuroinflammation, 2017;14(1):39.
    Species: Mouse
    Sample Types: Plasma
  104. C-type Lectin Mincle Recognizes Glucosyl-diacylglycerol of Streptococcus pneumoniae and Plays a Protective Role in Pneumococcal Pneumonia
    PLoS Pathog, 2016;12(12):e1006038.
    Species: Mouse
    Sample Types: Tissue Homogenates
  105. DNMT1-PPAR? pathway in macrophages regulates chronic inflammation and atherosclerosis development in mice
    Sci Rep, 2016;6(0):30053.
    Species: Mouse
    Sample Types: Plasma
  106. Key role for neutrophils in radiation-induced antitumor immune responses: Potentiation with G-CSF
    Proc Natl Acad Sci USA, 2016;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  107. A Critical Role for P2X7 Receptor-Induced VCAM-1 Shedding and Neutrophil Infiltration during Acute Lung Injury
    J Immunol, 2016;0(0):.
  108. Simvastatin promotes NPC1-mediated free cholesterol efflux from lysosomes through CYP7A1/LXR? signalling pathway in oxLDL-loaded macrophages
    J Cell Mol Med, 2016;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  109. Protective effect of Cl-amidine against CLP-induced lethal septic shock in mice
    Sci Rep, 2016;6(0):36696.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  110. Adverse Effect Profile of Topical Ocular Administration of Fingolimod for Treatment of Dry Eye Disease
    Authors: Weibao Xiao
    Basic Clin. Pharmacol. Toxicol, 2016;0(0):.
    Species: Mouse
    Sample Types: Tears
  111. Effects of the stem extracts of Schisandra glaucescens Diels on collagen-induced arthritis in Balb/c mice
    Authors: Jinbo Fang
    J Ethnopharmacol, 2016;0(0):.
    Species: Mouse
    Sample Types: Serum
  112. KLHDC10 Deficiency Protects Mice against TNF?-Induced Systemic Inflammation
    PLoS ONE, 2016;11(9):e0163118.
    Species: Mouse
    Sample Types: Serum
  113. Intravenous hMSCs Ameliorate Acute Pancreatitis in Mice via Secretion of Tumor Necrosis Factor-? Stimulated Gene/Protein 6
    Sci Rep, 2016;6(0):38438.
    Species: Mouse
    Sample Types: Serum
  114. Toll-Like Receptor 4 Signaling Pathway Mediates Inhalant Organic Dust-Induced Bone Loss
    PLoS ONE, 2016;11(8):e0158735.
    Species: Mouse
    Sample Types: BALF
  115. EP4 Receptor-Associated Protein in Macrophages Protects against Bleomycin-Induced Pulmonary Inflammation in Mice
    Authors: Manabu Minami
    J. Immunol., 2016;0(0):.
    Species: Mouse
    Sample Types: BALF
  116. Neutrophils suppress intraluminal NK-mediated tumor cell clearance and enhance extravasation of disseminated carcinoma cells
    Authors: A Spiegel, MW Brooks, S Houshyar, F Reinhardt, M Ardolino, E Fessler, MB Chen, JA Krall, J DeCock, IK Zervantona, A Iannello, Y Iwamoto, V Cortez-Ret, RD Kamm, MJ Pittet, DH Raulet, RA Weinberg
    Cancer Discov, 2016;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  117. Kruppel-like factor 6 promotes macrophage-mediated inflammation by suppressing B cell leukemia/lymphoma 6 expression
    J Biol Chem, 2016;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  118. Pyrin inflammasome activation and RhoA signaling in the autoinflammatory diseases FMF and HIDS
    Authors: Yong Hwan Park
    Nat Immunol, 2016;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  119. Sharpin Controls Osteogenic Differentiation of Mesenchymal Bone Marrow Cells.
    Authors: Jeschke A, Catala-Lehnen P, Sieber S, Bickert T, Schweizer M, Koehne T, Wintges K, Marshall R, Mautner A, Duchstein L, Otto B, Horst A, Amling M, Kreienkamp H, Schinke T
    J Immunol, 2015;195(8):3675-84.
    Species: Mouse
    Sample Types: Serum
  120. Critical role for IL-18 in spontaneous lung inflammation caused by autophagy deficiency.
    Authors: Abdel Fattah E, Bhattacharya A, Herron A, Safdar Z, Eissa N
    J Immunol, 2015;194(11):5407-16.
  121. Novel Noncompetitive IL-1 Receptor-Biased Ligand Prevents Infection- and Inflammation-Induced Preterm Birth.
    Authors: Nadeau-Vallee M, Quiniou C, Palacios J, Hou X, Erfani A, Madaan A, Sanchez M, Leimert K, Boudreault A, Duhamel F, Rivera J, Zhu T, Noueihed B, Robertson S, Ni X, Olson D, Lubell W, Girard S, Chemtob S
    J Immunol, 2015;195(7):3402-15.
    Species: Mouse
    Sample Types: Plasma
  122. Microglial Heparan Sulfate Proteoglycans Facilitate the Cluster-of-Differentiation 14 (CD14)/Toll-like Receptor 4 (TLR4)-Dependent Inflammatory Response.
    Authors: O'Callaghan P, Li J, Lannfelt L, Lindahl U, Zhang X
    J Biol Chem, 2015;290(24):14904-14.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  123. Methylsulfonylmethane inhibits NLRP3 inflammasome activation.
    Authors: Ahn H, Kim J, Lee M, Kim Y, Cho Y, Lee G
    Cytokine, 2015;71(2):223-31.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  124. Sevoflurane inhibits nuclear factor-kappaB activation in lipopolysaccharide-induced acute inflammatory lung injury via toll-like receptor 4 signaling.
    Authors: Sun X, Li X, Wang X, Tan W, Wang J
    PLoS ONE, 2015;10(4):e0122752.
    Species: Mouse
    Sample Types: BALF
  125. Chronic morphine-induced microRNA-124 promotes microglial immunosuppression by modulating P65 and TRAF6.
    Authors: Qiu S, Feng Y, LeSage G, Zhang Y, Stuart C, He L, Li Y, Caudle Y, Peng Y, Yin D
    J Immunol, 2015;194(3):1021-30.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  126. Pycnogenol Attenuates the Release of Proinflammatory Cytokines and Expression of Perilipin 2 in Lipopolysaccharide-Stimulated Microglia in Part via Inhibition of NF-kappaB and AP-1 Activation.
    Authors: Fan B, Dun S, Gu J, Guo Y, Ikuyama S
    PLoS ONE, 2015;10(9):e0137837.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  127. Local immunosuppressive microenvironment enhances migration of melanoma cells to lungs in DJ-1 knockout mice.
    Authors: Chien C, Lee M, Liou H, Liou H, Fu W
    PLoS ONE, 2015;10(2):e0115827.
    Species: Mouse
    Sample Types: Tissue Homogenates
  128. RIP3-mediated necrotic cell death accelerates systematic inflammation and mortality.
    Authors: Meng L, Jin W, Wang X
    Proc Natl Acad Sci U S A, 2015;112(35):11007-12.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  129. Accelerated tumor progression in mice lacking the ATP receptor P2X7.
    Authors: Adinolfi E, Capece M, Franceschini A, Falzoni S, Giuliani A, Rotondo A, Sarti A, Bonora M, Syberg S, Corigliano D, Pinton P, Jorgensen N, Abelli L, Emionite L, Raffaghello L, Pistoia V, Di Virgilio F
    Cancer Res, 2015;75(4):635-44.
    Species: Mouse
    Sample Types: Plasma
  130. Macrophage control of phagocytosed mycobacteria is increased by factors secreted by alveolar epithelial cells through nitric oxide independent mechanisms.
    Authors: Petursdottir D, Chuquimia O, Freidl R, Fernandez C
    PLoS ONE, 2014;9(8):e103411.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  131. NF-kappaB signaling modulates radiationinduced microglial activation.
    Authors: Xue J, Dong J, Huang G, Qu X, Wu G, Dong X
    Oncol Rep, 2014;31(6):2555-60.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  132. Running exercise alleviates trabecular bone loss and osteopenia in hemizygous beta-globin knockout thalassemic mice.
    Authors: Thongchote K, Svasti S, Teerapornpuntakit J, Krishnamra N, Charoenphandhu N
    Am J Physiol Endocrinol Metab, 2014;306(12):E1406-17.
    Species: Mouse
    Sample Types: Serum
  133. The inflammasome pyrin contributes to pertussis toxin-induced IL-1beta synthesis, neutrophil intravascular crawling and autoimmune encephalomyelitis.
    Authors: Dumas A, Amiable N, de Rivero Vaccari J, Chae J, Keane R, Lacroix S, Vallieres L
    PLoS Pathog, 2014;10(5):e1004150.
    Species: Mouse
    Sample Types: Peritoneal Fluid
  134. Improvement of spinal non-viral IL-10 gene delivery by D-mannose as a transgene adjuvant to control chronic neuropathic pain.
    Authors: Dengler E, Alberti L, Bowman B, Kerwin A, Wilkerson J, Moezzi D, Limanovich E, Wallace J, Milligan E
    J Neuroinflammation, 2014;11(0):92.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  135. CCL3 production by microglial cells modulates disease severity in murine models of retinal degeneration.
    Authors: Kohno H, Maeda T, Perusek L, Pearlman E, Maeda A
    J Immunol, 2014;192(8):3816-27.
    Species: Mouse
    Sample Types: Tissue Homogenates
  136. The effects of protein malnutrition on the TNF-RI and NF-kappaB expression via the TNF-alpha signaling pathway.
    Authors: de Oliveira D, Hastreiter A, Mello A, de Oliveira Beltran J, Oliveira Santos E, Borelli P, Fock R
    Cytokine, 2014;69(2):218-25.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  137. Diisopropylamine dichloroacetate, a novel pyruvate dehydrogenase kinase 4 inhibitor, as a potential therapeutic agent for metabolic disorders and multiorgan failure in severe influenza.
    Authors: Yamane, Kazuhiko, Indalao, Irene L, Chida, Junji, Yamamoto, Yoshikaz, Hanawa, Masaaki, Kido, Hiroshi
    PLoS ONE, 2014;9(5):e98032.
    Species: Mouse
    Sample Types: Tissue Homogenates
  138. Differences in PGE2 production between primary human monocytes and differentiated macrophages: role of IL-1beta and TRIF/IRF3.
    Authors: Endo Y, Blinova K, Romantseva T, Golding H, Zaitseva M
    PLoS ONE, 2014;9(5):e98517.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  139. Neurodegeneration by activation of the microglial complement-phagosome pathway.
    Authors: Bodea L, Wang Y, Linnartz-Gerlach B, Kopatz J, Sinkkonen L, Musgrove R, Kaoma T, Muller A, Vallar L, Di Monte D, Balling R, Neumann H
    J Neurosci, 2014;34(25):8546-56.
    Species: Mouse
    Sample Types: Plasma
  140. Akt2 deficiency protects from acute lung injury via alternative macrophage activation and miR-146a induction in mice.
    Authors: Vergadi, Eleni, Vaporidi, Katerina, Theodorakis, Emmanuel, Doxaki, Christin, Lagoudaki, Eleni, Ieronymaki, Elefther, Alexaki, Vassilia, Helms, Mike, Kondili, Eumorfia, Soennichsen, Birte, Stathopoulos, Efstathi, Margioris, Andrew N, Georgopoulos, Dimitrio, Tsatsanis, Christos
    J Immunol, 2014;192(1):394-406.
    Species: Mouse
    Sample Types: BALF
  141. PKM2 regulates the Warburg effect and promotes HMGB1 release in sepsis.
    Authors: Yang L, Xie M, Yang M, Yu Y, Zhu S, Hou W, Kang R, Lotze M, Billiar T, Wang H, Cao L, Tang D
    Nat Commun, 2014;5(0):4436.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  142. Celecoxib sensitizes Staphylococcus aureus to antibiotics in macrophages by modulating SIRT1.
    Authors: Annamanedi M, Kalle A
    PLoS ONE, 2014;9(6):e99285.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  143. Role of TLR5 and flagella in bacillus intraocular infection.
    Authors: Parkunan, Salai Ma, Astley, Roger, Callegan, Michelle
    PLoS ONE, 2014;9(6):e100543.
    Species: Mouse
    Sample Types: Tissue Homogenates
  144. Edwardsiella tarda-Induced cytotoxicity depends on its type III secretion system and flagellin.
    Authors: Xie H, Lu J, Rolhion N, Holden D, Nie P, Zhou Y, Yu X
    Infect Immun, 2014;82(8):3436-45.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  145. CCR1 inhibition ameliorates the progression of lupus nephritis in NZB/W mice.
    Authors: Bignon A, Gaudin F, Hemon P, Tharinger H, Mayol K, Walzer T, Loetscher P, Peuchmaur M, Berrebi D, Balabanian K
    J Immunol, 2014;192(3):886-96.
    Species: Mouse
    Sample Types: Serum
  146. Sufficient production of geranylgeraniol is required to maintain endotoxin tolerance in macrophages.
    Authors: Kim J, Lee J, Ye J, Hao R, Debose-Boyd R, Ye J
    J Lipid Res, 2013;54(12):3430-7.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  147. CXCL6 antibody neutralization prevents lung inflammation and fibrosis in mice in the bleomycin model.
    Authors: Besnard A, Struyf S, Guabiraba R, Fauconnier L, Rouxel N, Proost P, Uyttenhove C, Van Snick J, Couillin I, Ryffel B
    J Leukoc Biol, 2013;94(6):1317-23.
    Species: Mouse
    Sample Types: Tissue Homogenates
  148. Staphylococcus aureus sarA regulates inflammation and colonization during central nervous system biofilm formation.
    Authors: Snowden J, Beaver M, Beenken K, Smeltzer M, Horswill A, Kielian T
    PLoS ONE, 2013;8(12):e84089.
    Species: Mouse
    Sample Types: Tissue Homogenates
  149. Sirt2 suppresses inflammatory responses in collagen-induced arthritis.
    Authors: Lin J, Sun B, Jiang C, Hong H, Zheng Y
    Biochem Biophys Res Commun, 2013;441(4):897-903.
    Species: Mouse
    Sample Types: Serum
  150. Spironolactone attenuates bleomycin-induced pulmonary injury partially via modulating mononuclear phagocyte phenotype switching in circulating and alveolar compartments.
    Authors: Ji W, Ma Y, Zhou X, Zhang Y, Lu R, Guo Z, Sun H, Hu D, Yang G, Li Y, Wei L
    PLoS ONE, 2013;8(11):e81090.
    Species: Mouse
    Sample Types: BALF
  151. NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice.
    Authors: Heneka M, Kummer M, Stutz A, Delekate A, Schwartz S, Vieira-Saecker A, Griep A, Axt D, Remus A, Tzeng T, Gelpi E, Halle A, Korte M, Latz E, Golenbock D
    Nature, 2013;493(7434):674-8.
    Species: Mouse
    Sample Types: Tissue Homogenates
  152. Bcl-2 overexpression ameliorates immune complex-mediated arthritis by altering FcgammaRIIb expression and monocyte homeostasis.
    Authors: Lawlor K, van Nieuwenhuijze A, Parker K, Drake S, Campbell I, Smith S, Vince J, Strasser A, Wicks I
    J Leukoc Biol, 2013;93(4):585-97.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  153. Impaired bone formation and increased osteoclastogenesis in mice lacking chemokine (C-C motif) ligand 5 (Ccl5).
    Authors: Wintges K, Beil F, Albers J, Jeschke A, Schweizer M, Claass B, Tiegs G, Amling M, Schinke T
    J Bone Miner Res, 2013;28(10):2070-80.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  154. mTORC1 and mTORC2 play different roles in the functional survival of transplanted adipose-derived stromal cells in hind limb ischemic mice via regulating inflammation in vivo.
    Authors: Fan W, Cheng K, Qin X, Narsinh K, Wang S, Hu S, Wang Y, Chen Y, Wu J, Xiong L, Cao F
    Stem Cells, 2013;31(1):203-14.
    Species: Mouse
    Sample Types: Tissue Homogenates
  155. Targeted inhibition of serotonin type 7 (5-HT7) receptor function modulates immune responses and reduces the severity of intestinal inflammation.
    Authors: Kim, Janice J, Bridle, Byram W, Ghia, Jean-Eri, Wang, Huaqing, Syed, Shahzad, Manocha, Marcus M, Rengasamy, Palanive, Shajib, Mohammad, Wan, Yonghong, Hedlund, Peter B, Khan, Waliul I
    J Immunol, 2013;190(9):4795-804.
    Species: Mouse
    Sample Types: Tissue Homogenates
  156. A hydrogen sulfide-releasing cyclooxygenase inhibitor markedly accelerates recovery from experimental spinal cord injury.
    Authors: Campolo M, Esposito E, Ahmad A, Di Paola R, Wallace J, Cuzzocrea S
    FASEB J, 2013;27(11):4489-99.
    Species: Mouse
    Sample Types: Whole Tissue
  157. Treatment of diabetic mice with undenatured whey protein accelerates the wound healing process by enhancing the expression of MIP-1alpha, MIP-2, KC, CX3CL1 and TGF-beta in wounded tissue.
    BMC Immunol., 2012;13(0):32.
    Species: Mouse
    Sample Types: Tissue Homogenates
  158. Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1.
    Authors: Broz P, Ruby T, Belhocine K, Bouley D, Kayagaki N, Dixit V, Monack D
    Nature, 2012;490(7419):288-91.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  159. Exendin-4 protected against cognitive dysfunction in hyperglycemic mice receiving an intrahippocampal lipopolysaccharide injection.
    Authors: Huang H, Chen Y, Liang K, Jheng Y, Jhao J, Su M, Lee-Chen G, Hsieh-Li H
    PLoS ONE, 2012;7(7):e39656.
    Species: Mouse
    Sample Types: Plasma
  160. Inhibiting Mer receptor tyrosine kinase suppresses STAT1, SOCS1/3, and NF-kappaB activation and enhances inflammatory responses in lipopolysaccharide-induced acute lung injury.
    J. Cell. Sci., 2012;91(6):921-32.
    Species: Mouse
    Sample Types: BALF
  161. Dual functions of prostaglandin D2 in murine contact hypersensitivity via DP and CRTH2.
    Authors: Yamamoto Y, Otani S, Hirai H, Nagata K, Aritake K, Urade Y, Narumiya S, Yokozeki H, Nakamura M, Satoh T
    Am. J. Pathol., 2012;179(1):302-14.
    Species: Mouse
    Sample Types: Tissue Homogenates
  162. Activated protein C inhibits pancreatic islet inflammation, stimulates T regulatory cells, and prevents diabetes in non-obese diabetic (NOD) mice.
    Authors: Xue M, Dervish S, Harrison LC, Fulcher G, Jackson CJ
    J. Biol. Chem., 2012;287(20):16356-64.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  163. Netrin-1 protects against L-Arginine-induced acute pancreatitis in mice.
    Authors: Chen J, Cai Q, Shen P, Yan R, Wang C, Yang D, Fu H, Chen X
    PLoS ONE, 2012;7(9):e46201.
    Species: Mouse
    Sample Types: Plasma
  164. The axonal guidance receptor neogenin promotes acute inflammation.
    Authors: Konig K, Gatidou D, Granja T, Meier J, Rosenberger P, Mirakaj V
    PLoS ONE, 2012;7(3):e32145.
    Species: Mouse
    Sample Types: Peritoneal Lavage Fluid
  165. Toll-like receptor-mediated inhibition of Gas6 and ProS expression facilitates inflammatory cytokine production in mouse macrophages.
    Authors: Deng T, Zhang Y, Chen Q, Yan K, Han D
    Immunology, 2012;135(1):40-50.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  166. Modelling of mouse experimental colitis by global property screens: a holistic approach to assess drug effects in inflammatory bowel disease.
    Authors: Gottfries J, Melgar S, Michaelsson E
    PLoS ONE, 2012;7(1):e30005.
    Species: Mouse
    Sample Types: Tissue Homogenates
  167. Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth.
    Authors: Bruchard M, Mignot G, Derangere V, Chalmin F, Chevriaux A, Vegran F, Boireau W, Simon B, Ryffel B, Connat J, Kanellopoulos J, Martin F, Rebe C, Apetoh L, Ghiringhelli F
    Nat Med, 2012;19(1):57-64.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  168. Histone Deacetylase Inhibitor LAQ824 Augments Inflammatory Responses in Macrophages through Transcriptional Regulation of IL-10.
    Authors: Wang H, Cheng F
    J. Immunol., 2011;186(0):3986.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  169. Action at a distance: systemically administered adult stem/progenitor cells (MSCs) reduce inflammatory damage to the cornea without engraftment and primarily by secretion of TNF-alpha stimulated gene/protein 6.
    Authors: Roddy GW, Oh JY, Lee RH, Bartosh TJ, Ylostalo J, Coble K, Rosa RH, Prockop DJ
    Stem Cells, 2011;29(10):1572-9.
    Species: Mouse
    Sample Types: Tissue Homogenates
  170. Serotonin activates dendritic cell function in the context of gut inflammation.
    Authors: Li N, Ghia JE, Wang H, McClemens J, Cote F, Suehiro Y, Mallet J, Khan WI
    Am. J. Pathol., 2011;178(2):662-71.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  171. Anti-inflammatory role of microsomal prostaglandin E synthase-1 in a model of neuroinflammation.
    Authors: Brenneis C, Coste O, Altenrath K, Angioni C, Schmidt H, Schuh CD, Zhang DD, Henke M, Weigert A, Brune B, Rubin B, Nusing R, Scholich K, Geisslinger G
    J. Biol. Chem., 2011;286(3):2331-42.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  172. Fasting induces an anti-inflammatory effect on the neuroimmune system which a high-fat diet prevents.
    Authors: Lavin DN, Joesting JJ, Chiu GS, Moon ML, Meng J, Dilger RN, Freund GG
    Obesity (Silver Spring), 2011;19(8):1586-94.
    Species: Mouse
    Sample Types: Serum
  173. Sphingosine regulates the NLRP3-inflammasome and IL-1beta release from macrophages.
    Authors: Luheshi NM, Giles JA, Lopez-Castejon G, Brough D
    Eur. J. Immunol., 2011;42(3):716-25.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  174. TLR4 through IFN-beta promotes low molecular mass hyaluronan-induced neutrophil apoptosis.
    Authors: Leu SW, Shi L, Xu C, Zhao Y, Liu B, Li Y, Shiedlin A, Xiang C, Shen H, Quinn DA, Hales CA, Zhao H
    J. Immunol., 2011;186(1):556-62.
    Species: Mouse
    Sample Types: BALF
  175. Role of IL-1alpha and the Nlrp3/caspase-1/IL-1beta axis in cigarette smoke-induced pulmonary inflammation and COPD.
    Authors: Pauwels NS, Bracke KR, Dupont LL, Van Pottelberge GR, Provoost S, Vanden Berghe T, Vandenabeele P, Lambrecht BN, Joos GF, Brusselle GG
    Eur. Respir. J., 2011;38(5):1019-28.
    Species: Mouse
    Sample Types: BALF
  176. WNT5A Signaling Contributes to Abeta-Induced Neuroinflammation and Neurotoxicity.
    Authors: Li B, Zhong L, Yang X, Andersson T, Huang M, Tang SJ
    PLoS ONE, 2011;6(8):e22920.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  177. Repulsive guidance molecule-A (RGM-A) inhibits leukocyte migration and mitigates inflammation.
    Authors: Mirakaj V, Brown S, Laucher S, Steinl C, Klein G, Kohler D, Skutella T, Meisel C, Brommer B, Rosenberger P, Schwab JM
    Proc. Natl. Acad. Sci. U.S.A., 2011;108(16):6555-60.
    Species: Mouse
    Sample Types: Peritoneal Lavage Fluid
  178. Transgenic expression of human cathepsin B promotes progression and metastasis of polyoma-middle-T-induced breast cancer in mice.
    Authors: Sevenich L, Werner F, Gajda M, Schurigt U, Sieber C, Muller S, Follo M, Peters C, Reinheckel T
    Oncogene, 2011;30(1):54-64.
    Species: Mouse
    Sample Types: Tissue Homogenates
  179. IL-33-activated dendritic cells are critical for allergic airway inflammation.
    Authors: Besnard AG, Togbe D, Guillou N, Erard F, Quesniaux V, Ryffel B
    Eur. J. Immunol., 2011;41(6):1675-86.
    Species: Mouse
    Sample Types: BALF
  180. Crawling Phagocytes Recruited in the Brain Vasculature after Pertussis Toxin Exposure through IL6, ICAM1 and ITGalphaM.
    Authors: Richard JF, Roy M, Audoy-Remus J, Tremblay P, Vallieres L
    Brain Pathol., 2011;21(0):661.
    Species: Mouse
    Sample Types: Serum
  181. HIF-VEGF pathways are critical for chronic otitis media in Junbo and Jeff mouse mutants.
    Authors: Cheeseman MT, Tyrer HE, Williams D, Hough TA, Pathak P, Romero MR, Hilton H, Bali S, Parker A, Vizor L, Purnell T, Vowell K, Wells S, Bhutta MF, Potter PK, Brown SD
    PLoS Genet., 2011;7(10):e1002336.
    Species: Mouse
    Sample Types: Serum
  182. Deletion of tristetraprolin caused spontaneous reactive granulopoiesis by a non-cell-autonomous mechanism without disturbing long-term hematopoietic stem cell quiescence.
    Authors: Kaplan IM, Morisot S, Heiser D, Cheng WC, Kim MJ, Civin CI
    J. Immunol., 2011;186(5):2826-34.
    Species: Mouse
    Sample Types: Plasma
  183. Aryl hydrocarbon receptor deficiency in T cells suppresses the development of collagen-induced arthritis.
    Authors: Nakahama T, Kimura A, Nguyen NT, Chinen I, Hanieh H, Nohara K, Fujii-Kuriyama Y, Kishimoto T
    Proc. Natl. Acad. Sci. U.S.A., 2011;108(34):14222-7.
    Species: Mouse
    Sample Types: Serum
  184. Early protection from burn-induced acute lung injury by deletion of preprotachykinin-A gene.
    Authors: Sio SW, Moochhala S, Lu J
    Am. J. Respir. Crit. Care Med., 2010;181(1):36-46.
    Species: Mouse
    Sample Types: Tissue Homogenates
  185. Epithelial overexpression of SOCS-3 in transgenic mice exacerbates wound inflammation in the presence of elevated TGF-beta1.
    Authors: Linke A, Goren I, Bosl MR, Pfeilschifter J, Frank S
    J. Invest. Dermatol., 2010;130(3):866-75.
    Species: Mouse
    Sample Types: Tissue Homogenates
  186. Galectin-3 contributes to neonatal hypoxic-ischemic brain injury.
    Authors: Doverhag C, Hedtjarn M, Poirier F, Mallard C, Hagberg H, Karlsson A, Savman K
    Neurobiol. Dis., 2010;38(1):36-46.
    Species: Mouse
    Sample Types: Tissue Homogenates
  187. Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1beta in type 2 diabetes.
    Authors: Masters SL, Dunne A, Subramanian SL, Hull RL, Tannahill GM, Sharp FA, Becker C, Franchi L, Yoshihara E, Chen Z, Mullooly N, Mielke LA, Harris J, Coll RC, Mills KH, Mok KH, Newsholme P, Nunez G, Yodoi J, Kahn SE, Lavelle EC, O'Neill LA
    Nat. Immunol., 2010;11(10):897-904.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  188. Microbial exposure early in life regulates airway inflammation in mice after infection with Streptococcus pneumoniae with enhancement of local resistance.
    Authors: Yasuda Y, Matsumura Y, Kasahara K, Ouji N, Sugiura S, Mikasa K, Kita E
    Am. J. Physiol. Lung Cell Mol. Physiol., 2010;298(1):L67-78.
    Species: Mouse
    Sample Types: BALF
  189. Systemic inflammation sensitizes the neonatal brain to excitotoxicity through a pro-/anti-inflammatory imbalance: key role of TNFalpha pathway and protection by etanercept.
    Authors: Aden U, Favrais G, Plaisant F, Winerdal M, Felderhoff-Mueser U, Lampa J, Lelievre V, Gressens P
    Brain Behav. Immun., 2010;24(5):747-58.
    Species: Mouse
    Sample Types: Tissue Homogenates
  190. TLR4 is a negative regulator in noninfectious lung inflammation.
    Authors: Zhao H, Leu SW, Shi L, Dedaj R, Zhao G, Garg HG, Shen L, Lien E, Fitzgerald KA, Shiedlin A, Shen H, Quinn DA, Hales CA
    J. Immunol., 2010;184(9):5308-14.
    Species: Mouse
    Sample Types: BALF
  191. Cytotoxins of the human pathogen Aeromonas hydrophila trigger, via the NLRP3 inflammasome, caspase-1 activation in macrophages.
    Authors: McCoy AJ, Koizumi Y, Toma C, Higa N, Dixit V, Taniguchi S, Tschopp J, Suzuki T
    Eur. J. Immunol., 2010;40(10):2797-803.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  192. Loss of ability to self-heal malaria upon taurine transporter deletion.
    Authors: Delic D, Warskulat U, Borsch E, Al-Qahtani S, Al-Quraishi S, Haussinger D, Wunderlich F
    Infect. Immun., 2010;78(4):1642-9.
    Species: Mouse
    Sample Types: Serum
  193. Evidence that intrathecal morphine-3-glucuronide may cause pain enhancement via toll-like receptor 4/MD-2 and interleukin-1beta.
    Authors: Lewis SS, Hutchinson MR, Rezvani N, Loram LC, Zhang Y, Maier SF, Rice KC, Watkins LR
    Neuroscience, 2010;165(2):569-83.
    Species: Mouse
    Sample Types: Cell Lysates
  194. Absence or inhibition of matrix metalloproteinase-8 decreases ventilator-induced lung injury.
    Authors: Albaiceta GM, Gutierrez-Fernandez A, Garcia-Prieto E, Puente XS, Parra D, Astudillo A, Campestre C, Cabrera S, Gonzalez-Lopez A, Fueyo A, Taboada F, Lopez-Otin C
    Am. J. Respir. Cell Mol. Biol., 2010;43(5):555-63.
    Species: Mouse
    Sample Types: Tissue Homogenates
  195. Anti-inflammatory effects of ethyl acetate fraction from Melilotus suaveolens Ledeb on LPS-stimulated RAW 264.7 cells.
    Authors: Tao JY, Zheng GH, Zhao L, Wu JG, Zhang XY, Zhang SL, Huang ZJ, Xiong FL, Li CM
    J Ethnopharmacol, 2009;123(1):97-105.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  196. Differential IL-23 requirement for IL-22 and IL-17A production during innate immunity against Salmonella enterica serovar Enteritidis.
    Authors: Siegemund S, Schutze N, Schulz S, Wolk K, Nasilowska K, Straubinger RK, Sabat R, Alber G
    Int. Immunol., 2009;21(5):555-65.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  197. Tumor necrosis factor-alpha and interleukin-1 antagonists alleviate inflammatory skin changes associated with epidermal growth factor receptor antibody therapy in mice.
    Authors: Surguladze D, Deevi D, Claros N, Corcoran E, Wang S, Plym MJ, Wu Y, Doody J, Mauro DJ, Witte L, Busam KJ, Pytowski B, Rodeck U, Tonra JR
    Cancer Res., 2009;69(14):5643-7.
    Species: Mouse
    Sample Types: Tissue Homogenates
  198. VAMP8 is essential in anaphylatoxin-induced degranulation, TNF-alpha secretion, peritonitis, and systemic inflammation.
    Authors: Pushparaj PN, Tay HK, Wang CC, Hong W, Melendez AJ
    J. Immunol., 2009;183(2):1413-8.
    Species: Mouse
    Sample Types: Serum
  199. T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes.
    Authors: Guarda G, Dostert C, Staehli F, Cabalzar K, Castillo R, Tardivel A, Schneider P, Tschopp J
    Nature, 2009;460(7252):269-73.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  200. Inhibitory effect of atractylenolide I on angiogenesis in chronic inflammation in vivo and in vitro.
    Authors: Wang C, Duan H, He L
    Eur. J. Pharmacol., 2009;612(1):143-52.
    Species: Mouse
    Sample Types: Air Pouch Exudate
  201. A MyD88-dependent early IL-17 production protects mice against airway infection with the obligate intracellular pathogen Chlamydia muridarum.
    Authors: Zhang X, Gao L, Lei L, Zhong Y, Dube P, Berton MT, Arulanandam B, Zhang J, Zhong G
    J. Immunol., 2009;183(2):1291-300.
    Species: Mouse
    Sample Types: BALF
  202. Complement C3a regulates late asthmatic response and airway hyperresponsiveness in mice.
    Authors: Mizutani N, Nabe T, Yoshino S
    J. Immunol., 2009;183(6):4039-46.
    Species: Mouse
    Sample Types: BALF
  203. C/EBPalpha is required for pulmonary cytoprotection during hyperoxia.
    Authors: Xu Y, Saegusa C, Schehr A, Grant S, Whitsett JA, Ikegami M
    Am. J. Physiol. Lung Cell Mol. Physiol., 2009;297(2):L286-98.
    Species: Mouse
    Sample Types: Tissue Homogenates
  204. NOD1 expression in the eye and functional contribution to IL-1beta-dependent ocular inflammation in mice.
    Authors: Rosenzweig HL, Galster KT, Planck SR, Rosenbaum JT
    Invest. Ophthalmol. Vis. Sci., 2009;50(4):1746-53.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  205. Intravenous tolerance modulates macrophage classical activation and antigen presentation in experimental autoimmune encephalomyelitis.
    Authors: Li H, Ciric B, Yang J, Xu H, Fitzgerald DC, Elbehi M, Fonseca-Kelly Z, Yu S, Zhang GX, Rostami A
    J. Neuroimmunol., 2009;208(1):54-60.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  206. Bbeta(15-42) protects against acid-induced acute lung injury and secondary pseudomonas pneumonia in vivo.
    Authors: Matt U, Warszawska JM, Bauer M, Dietl W, Mesteri I, Doninger B, Haslinger I, Schabbauer G, Perkmann T, Binder CJ, Reingruber S, Petzelbauer P, Knapp S
    Am. J. Respir. Crit. Care Med., 2009;180(12):1208-17.
    Species: Mouse
    Sample Types: BALF
  207. p47phox deficiency induces macrophage dysfunction resulting in progressive crystalline macrophage pneumonia.
    Authors: Liu Q, Cheng LI, Yi L, Zhu N, Wood A, Changpriroa CM, Ward JM, Jackson SH
    Am. J. Pathol., 2009;174(1):153-63.
    Species: Mouse
    Sample Types: BALF
  208. A small molecule CRTH2 antagonist inhibits FITC-induced allergic cutaneous inflammation.
    Authors: Boehme SA, Franz-Bacon K, Chen EP, Sasik R, Sprague LJ, Ly TW, Hardiman G, Bacon KB
    Int. Immunol., 2009;21(1):81-93.
    Species: Mouse
    Sample Types: Tissue Homogenates
  209. Hypoxia-inducible factor-dependent induction of netrin-1 dampens inflammation caused by hypoxia.
    Authors: Rosenberger P, Schwab JM, Mirakaj V, Masekowsky E, Mager A, Morote-Garcia JC, Unertl K, Eltzschig HK
    Nat. Immunol., 2009;10(2):195-202.
    Species: Mouse
    Sample Types: Serum
  210. Inhibition of monocyte-derived inflammatory cytokines by IL-25 occurs via p38 Map kinase-dependent induction of Socs-3.
    Authors: Caruso R, Stolfi C, Sarra M, Rizzo A, Fantini MC, Pallone F, MacDonald TT, Monteleone G
    Blood, 2009;113(15):3512-9.
    Species: Mouse
    Sample Types: Serum
  211. Interleukin-1beta and fibroblast growth factor receptor 1 cooperate to induce cyclooxygenase-2 during early mammary tumourigenesis.
    Authors: Reed JR, Leon RP, Hall MK, Schwertfeger KL
    Breast Cancer Res., 2009;11(2):R21.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  212. Syndecan-1 shedding facilitates the resolution of neutrophilic inflammation by removing sequestered CXC chemokines.
    Authors: Hayashida K, Parks WC, Park PW
    Blood, 2009;114(14):3033-43.
    Species: Mouse
    Sample Types: Serum
  213. Plasminogen activator inhibitor-1 regulates neutrophil influx during acute pyelonephritis.
    Authors: Roelofs JJ, Teske GJ, Bonta PI, de Vries CJ, Meijers JC, Weening JJ, van der Poll T, Florquin S
    Kidney Int., 2009;75(1):52-9.
    Species: Mouse
    Sample Types: Tissue Homogenates
  214. Chrysanthemum indicum Linne extract inhibits the inflammatory response by suppressing NF-kappaB and MAPKs activation in lipopolysaccharide-induced RAW 264.7 macrophages.
    Authors: Cheon MS, Yoon T, Lee do Y, Choi G, Moon BC, Lee AY, Choo BK, Kim HK
    J Ethnopharmacol, 2009;122(3):473-7.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  215. Secretory lysosome targeting and induced secretion of human soluble TNF-alpha receptor in murine hematopoietic cells in vivo as a principle for immunoregulation in inflammation and malignancy.
    Authors: Johansson AC, Nandakumar KS, Persson AM, Olsson I, Hansson M
    Exp. Hematol., 2009;37(8):969-78.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  216. Antifibrotic action of pirfenidone and prednisolone: different effects on pulmonary cytokines and growth factors in bleomycin-induced murine pulmonary fibrosis.
    Authors: Oku H, Shimizu T, Kawabata T, Nagira M, Hikita I, Ueyama A, Matsushima S, Torii M, Arimura A
    Eur. J. Pharmacol., 2008;590(1):400-8.
    Species: Mouse
    Sample Types: Tissue Homogenates
  217. Functional roles for C5a receptors in sepsis.
    Authors: Rittirsch D, Flierl MA, Nadeau BA, Day DE, Huber-Lang M, Mackay CR, Zetoune FS, Gerard NP, Cianflone K, Kohl J, Gerard C, Sarma JV, Ward PA
    Nat. Med., 2008;14(5):551-7.
    Species: Mouse
    Sample Types: Plasma
  218. Mouse models of rhinovirus-induced disease and exacerbation of allergic airway inflammation.
    Authors: Bartlett NW, Walton RP, Edwards MR, Aniscenko J, Caramori G, Zhu J, Glanville N, Choy KJ, Jourdan P, Burnet J, Tuthill TJ, Pedrick MS, Hurle MJ, Plumpton C, Sharp NA, Bussell JN, Swallow DM, Schwarze J, Guy B, Almond JW, Jeffery PK, Lloyd CM, Papi A, Killington RA, Rowlands DJ, Blair ED, Clarke NJ, Johnston SL
    Nat. Med., 2008;14(2):199-204.
    Species: Mouse
    Sample Types: BALF
  219. Peroxisome proliferator-activated receptor-gamma ligand, 15-deoxy-Delta12,14-prostaglandin J2, reduces neutrophil migration via a nitric oxide pathway.
    Authors: Napimoga MH, Vieira SM, Dal-Secco D, Freitas A, Souto FO, Mestriner FL, Alves-Filho JC, Grespan R, Kawai T, Ferreira SH, Cunha FQ
    J. Immunol., 2008;180(1):609-17.
    Species: Mouse
    Sample Types: Tissue Secretion
  220. The neuropeptide substance P is a critical mediator of burn-induced acute lung injury.
    Authors: Sio SW, Puthia MK, Lu J, Moochhala S, Bhatia M
    J. Immunol., 2008;180(12):8333-41.
    Species: Mouse
    Sample Types: Tissue Homogenates
  221. Adverse functions of IL-17A in experimental sepsis.
    Authors: Flierl MA, Rittirsch D, Gao H, Hoesel LM, Nadeau BA, Day DE, Zetoune FS, Sarma JV, Huber-Lang MS, Ferrara JL, Ward PA
    FASEB J., 2008;22(7):2198-205.
    Species: Mouse
    Sample Types: Plasma
  222. The NALP3 inflammasome is involved in the innate immune response to amyloid-beta.
    Authors: Halle A, Hornung V, Petzold GC, Stewart CR, Monks BG, Reinheckel T, Fitzgerald KA, Latz E, Moore KJ, Golenbock DT
    Nat. Immunol., 2008;9(8):857-65.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  223. Endogenous hydrogen sulfide regulates inflammatory response by activating the ERK pathway in polymicrobial sepsis.
    Authors: Zhang H, Moochhala SM, Bhatia M
    J. Immunol., 2008;181(6):4320-31.
    Species: Mouse
    Sample Types: Tissue Homogenates
  224. CT20126, a novel immunosuppressant, prevents collagen-induced arthritis through the down-regulation of inflammatory gene expression by inhibiting NF-kappaB activation.
    Authors: Lee SJ, Nam WD, Na HJ, Cho YL, Ha KS, Hwang JY, Lee H, Kim SO, Kwon YG, Kim YM
    Biochem. Pharmacol., 2008;76(1):79-90.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  225. Pharmacological and genetic inhibition of NADPH oxidase does not reduce brain damage in different models of perinatal brain injury in newborn mice.
    Authors: Doverhag C, Keller M, Karlsson A, Hedtjarn M, Nilsson U, Kapeller E, Sarkozy G, Klimaschewski L, Humpel C, Hagberg H, Simbruner G, Gressens P, Savman K
    Neurobiol. Dis., 2008;31(1):133-44.
    Species: Mouse
    Sample Types: Tissue Homogenates
  226. Inflamed phenotype of the mesenteric microcirculation of melanocortin type 3 receptor-null mice after ischemia-reperfusion.
    Authors: Leoni G, Patel HB, Sampaio AL, Gavins FN, Murray JF, Grieco P, Getting SJ, Perretti M
    FASEB J., 2008;22(12):4228-38.
    Species: Mouse
    Sample Types: Plasma
  227. Activation of NOD2 in vivo induces IL-1beta production in the eye via caspase-1 but results in ocular inflammation independently of IL-1 signaling.
    Authors: Rosenzweig HL, Martin TM, Planck SR, Galster K, Jann MM, Davey MP, Kobayashi K, Flavell RA, Rosenbaum JT
    J. Leukoc. Biol., 2008;84(2):529-36.
    Species: Mouse
    Sample Types: Tissue Homogenates
  228. Myeloid Src kinases regulate phagocytosis and oxidative burst in pneumococcal meningitis by activating NADPH oxidase.
    Authors: Paul R, Obermaier B, Van Ziffle J, Angele B, Pfister HW, Lowell CA, Koedel U
    J. Leukoc. Biol., 2008;84(4):1141-50.
    Species: Mouse
    Sample Types: Tissue Homogenates
  229. Tranilast, an orally active anti-allergic drug, up-regulates the anti-inflammatory heme oxygenase-1 expression but down-regulates the pro-inflammatory cyclooxygenase-2 and inducible nitric oxide synthase expression in RAW264.7 macrophages.
    Authors: Pae HO, Jeong SO, Koo BS, Ha HY, Lee KM, Chung HT
    Biochem. Biophys. Res. Commun., 2008;371(3):361-5.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  230. Purine receptor antagonist modulates serology and affective behaviors in lupus-prone mice: evidence of autoimmune-induced pain?
    Authors: Ballok DA, Sakic B
    Brain Behav. Immun., 2008;0(0):.
    Species: Mouse
    Sample Types: Serum
  231. Tumor-infiltrating myeloid-derived suppressor cells are pleiotropic-inflamed monocytes/macrophages that bear M1- and M2-type characteristics.
    Authors: Umemura N, Saio M, Suwa T, Kitoh Y, Bai J, Nonaka K, Ouyang GF, Okada M, Balazs M, Adany R, Shibata T, Takami T
    J. Leukoc. Biol., 2008;83(5):1136-44.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  232. Mice lacking NKCC1 are protected from development of bacteremia and hypothermic sepsis secondary to bacterial pneumonia.
    Authors: Nguyen M, Pace AJ, Koller BH
    J. Exp. Med., 2007;204(6):1383-93.
    Species: Mouse
    Sample Types: Tissue Homogenates
  233. Cell-based angiopoietin-1 gene therapy for acute lung injury.
    Authors: McCarter SD, Mei SH, Lai PF, Zhang QW, Parker CH, Suen RS, Hood RD, Zhao YD, Deng Y, Han RN, Dumont DJ, Stewart DJ
    Am. J. Respir. Crit. Care Med., 2007;175(10):1014-26.
    Species: Mouse
    Sample Types: BALF
  234. ST2 is essential for Th2 responsiveness and resistance to pseudomonas aeruginosa keratitis.
    Authors: Huang X, Du W, Barrett RP, Hazlett LD
    Invest. Ophthalmol. Vis. Sci., 2007;48(10):4626-33.
    Species: Mouse
    Sample Types: Tissue Homogenates
  235. Cathelicidin-deficient (Cnlp -/- ) mice show increased susceptibility to Pseudomonas aeruginosa keratitis.
    Authors: Huang LC, Reins RY, Gallo RL, McDermott AM
    Invest. Ophthalmol. Vis. Sci., 2007;48(10):4498-508.
    Species: Mouse
    Sample Types: Tissue Homogenates
  236. Interleukin-1beta is the primary initiator of pulmonary inflammation following liver injury in mice.
    Authors: Glasgow SC, Ramachandran S, Blackwell TS, Mohanakumar T, Chapman WC
    Am. J. Physiol. Lung Cell Mol. Physiol., 2007;293(2):L491-6.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  237. Neuronal NF-kappaB influences thermoregulation and survival in a sepsis model.
    Authors: Juttler E, Inta I, Eigler V, Herrmann O, Maegele I, Maser-Gluth C, Schwaninger M
    J. Neuroimmunol., 2007;189(1):41-9.
    Species: Mouse
    Sample Types: Serum
  238. Acute brain injury triggers MyD88-dependent, TLR2/4-independent inflammatory responses.
    Authors: Koedel U, Merbt UM, Schmidt C, Angele B, Popp B, Wagner H, Pfister HW, Kirschning CJ
    Am. J. Pathol., 2007;171(1):200-13.
    Species: Mouse
    Sample Types: Tissue Homogenates
  239. Astragali Radix elicits anti-inflammation via activation of MKP-1, concomitant with attenuation of p38 and Erk.
    Authors: Ryu M, Kim EH, Chun M, Kang S, Shim B, Yu YB, Jeong G, Lee JS
    J Ethnopharmacol, 2007;115(2):184-93.
    Species: Mouse
    Sample Types: Air Pouch Exudate
  240. Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock.
    Authors: Vogl T, Tenbrock K, Ludwig S, Leukert N, Ehrhardt C, van Zoelen MA, Nacken W, Foell D, van der Poll T, Sorg C, Roth J
    Nat. Med., 2007;13(9):1042-9.
    Species: Mouse
    Sample Types: Serum
  241. The immunomodulation of endotoxin-induced acute lung injury by hesperidin in vivo and in vitro.
    Authors: Yeh CC, Kao SJ, Lin CC, Wang SD, Liu CJ, Kao ST
    Life Sci., 2007;80(20):1821-31.
    Species: Mouse
    Sample Types: BALF
  242. Toll-like receptor 4 (TLR4)-dependent proinflammatory and immunomodulatory properties of the glycoinositolphospholipid (GIPL) from Trypanosoma cruzi.
    Authors: Medeiros MM, Peixoto JR, Oliveira AC, Cardilo-Reis L, Koatz VL, Van Kaer L, Previato JO, Mendonca-Previato L, Nobrega A, Bellio M
    J. Leukoc. Biol., 2007;82(3):488-96.
    Species: Mouse
    Sample Types: Peritoneal Fluid
  243. Identification of an immune-responsive mesolimbocortical serotonergic system: potential role in regulation of emotional behavior.
    Authors: Lowry CA, Hollis JH, de Vries A, Pan B, Brunet LR, Hunt JR, Paton JF, van Kampen E, Knight DM, Evans AK, Rook GA, Lightman SL
    Neuroscience, 2007;146(2):756-72.
    Species: Mouse
    Sample Types: Plasma
  244. Toll-like receptor 4 mediates the early inflammatory response after cold ischemia/reperfusion.
    Authors: Kaczorowski DJ, Nakao A, Mollen KP, Vallabhaneni R, Sugimoto R, Kohmoto J, Tobita K, Zuckerbraun BS, McCurry KR, Murase N, Billiar TR
    Transplantation, 2007;84(10):1279-87.
    Species: Mouse
    Sample Types: Serum
  245. The direct action of 1alpha,25(OH)2-vitamin D3 on purified mouse Langerhans cells.
    Authors: Fujita H, Asahina A, Komine M, Tamaki K
    Cell. Immunol., 2007;245(2):70-9.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  246. Maternal immune activation alters fetal brain development through interleukin-6.
    Authors: Smith SE, Li J, Garbett K, Mirnics K, Patterson PH
    J. Neurosci., 2007;27(40):10695-702.
    Species: Mouse
    Sample Types: Serum
  247. Clostridium sordellii lethal toxin kills mice by inducing a major increase in lung vascular permeability.
    Authors: Geny B, Khun H, Fitting C, Zarantonelli L, Mazuet C, Cayet N, Szatanik M, Prevost MC, Cavaillon JM, Huerre M, Popoff MR
    Am. J. Pathol., 2007;170(3):1003-17.
    Species: Mouse
    Sample Types: Serum
  248. Soluble vascular endothelial growth factor receptor-1 protects mice in sepsis.
    Authors: Tsao PN, Chan FT, Wei SC, Hsieh WS, Chou HC, Su YN, Chen CY, Hsu WM, Hsieh FJ, Hsu SM
    Crit. Care Med., 2007;35(8):1955-60.
    Species: Mouse
    Sample Types: Plasma
  249. The flavonoid baicalin protects against cerebrovascular dysfunction and brain inflammation in experimental heatstroke.
    Authors: Chang CP, Huang WT, Cheng BC, Hsu CC, Lin MT
    Neuropharmacology, 2007;52(3):1024-33.
    Species: Mouse
    Sample Types: Serum
  250. Absence of IL-1 receptor antagonist impaired wound healing along with aberrant NF-kappaB activation and a reciprocal suppression of TGF-beta signal pathway.
    Authors: Ishida Y, Kondo T, Kimura A, Matsushima K, Mukaida N
    J. Immunol., 2006;176(9):5598-606.
    Species: Mouse
    Sample Types: Tissue Homogenates
  251. [D-Trp8]-gamma-melanocyte-stimulating hormone exhibits anti-inflammatory efficacy in mice bearing a nonfunctional MC1R (recessive yellow e/e mouse).
    Authors: Getting SJ, Lam CW, Leoni G, Gavins FN, Grieco P, Perretti M
    Mol. Pharmacol., 2006;70(6):1850-5.
    Species: Mouse
    Sample Types: Peritoneal Lavage Fluid
  252. The urokinase plasminogen activator receptor is crucially involved in host defense during acute pyelonephritis.
    Authors: Roelofs JJ, Rouschop KM, Teske GJ, Claessen N, Weening JJ, van der Poll T, Florquin S
    Kidney Int., 2006;70(11):1942-7.
    Species: Mouse
    Sample Types: Tissue Homogenates
  253. Inhalation of ultrafine carbon particles triggers biphasic pro-inflammatory response in the mouse lung.
    Authors: Andre E, Stoeger T, Takenaka S, Bahnweg M, Ritter B, Karg E, Lentner B, Reinhard C, Schulz H, Wjst M
    Eur. Respir. J., 2006;28(2):275-85.
    Species: Mouse
    Sample Types: BALF
  254. CD27 contributes to the early systemic immune response to Mycobacterium tuberculosis infection but does not affect outcome.
    Authors: Wieland CW, Kerver ME, Florquin S, Nolte MA, Borst J, van Lier R, van Oers MH, van der Poll T
    Int. Immunol., 2006;18(11):1531-9.
  255. GM-CSF and the impaired pulmonary innate immune response following hyperoxic stress.
    Authors: Baleeiro CE, Christensen PJ, Morris SB, Mendez MP, Wilcoxen SE, Paine R
    Am. J. Physiol. Lung Cell Mol. Physiol., 2006;291(6):L1246-55.
    Species: Mouse
    Sample Types: Tissue Homogenates
  256. Gender differences in murine airway responsiveness and lipopolysaccharide-induced inflammation.
    Authors: Card JW, Carey MA, Bradbury JA, DeGraff LM, Morgan DL, Moorman MP, Flake GP, Zeldin DC
    J. Immunol., 2006;177(1):621-30.
    Species: Mouse
    Sample Types: BALF
  257. Organ-specific role of MyD88 for gene regulation during polymicrobial peritonitis.
    Authors: Weighardt H, Mages J, Jusek G, Kaiser-Moore S, Lang R, Holzmann B
    Infect. Immun., 2006;74(6):3618-32.
    Species: Mouse
    Sample Types: Tissue Homogenates
  258. Bim deficiency leads to exacerbation and prolongation of joint inflammation in experimental arthritis.
    Authors: Scatizzi JC, Bickel E, Hutcheson J, Haines GK, Perlman H
    Arthritis Rheum., 2006;54(10):3182-93.
    Species: Mouse
    Sample Types: Tissue Homogenates
  259. Tetrathiomolybdate is effective in a mouse model of arthritis.
    Authors: McCubbin MD, Hou G, Abrams GD, Dick R, Brewer GJ
    J. Rheumatol., 2006;33(12):2501-6.
    Species: Mouse
    Sample Types: Serum
  260. Allergic airway inflammation inhibits pulmonary antibacterial host defense.
    Authors: Beisswenger C, Kandler K, Hess C, Garn H, Felgentreff K, Wegmann M, Renz H, Vogelmeier C, Bals R
    J. Immunol., 2006;177(3):1833-7.
    Species: Mouse
    Sample Types: BALF
  261. Vaccinia virus infection attenuates innate immune responses and antigen presentation by epidermal dendritic cells.
    Authors: Deng L, Dai P, Ding W, Granstein RD, Shuman S
    J. Virol., 2006;80(20):9977-87.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  262. Protease-activated receptor-2 activation: a major role in the pathogenesis of Porphyromonas gingivalis infection.
    Authors: Holzhausen M, Spolidorio LC, Ellen RP, Jobin MC, Steinhoff M, Andrade-Gordon P, Vergnolle N
    Am. J. Pathol., 2006;168(4):1189-99.
    Species: Mouse
    Sample Types: Blister Fluid
  263. Citrus polymethoxylated flavones improve lipid and glucose homeostasis and modulate adipocytokines in fructose-induced insulin resistant hamsters.
    Authors: Li RW, Theriault AG, Au K, Douglas TD, Casaschi A, Kurowska EM, Mukherjee R
    Life Sci., 2006;79(4):365-73.
    Species: Mouse
    Sample Types: Serum
  264. Endogenous interleukin-12 improves the early antimicrobial host response to murine Escherichia coli peritonitis.
    Authors: Weijer S, Florquin S, van der Poll T
    Shock, 2005;23(1):54-8.
    Species: Mouse
    Sample Types: Peritoneal Fluid
  265. Responses of guinea pig pups during isolation in a novel environment may represent stress-induced sickness behaviors.
    Authors: Hennessy MB, Deak T, Schiml-Webb PA, Wilson SE, Greenlee TM, McCall E
    Physiol. Behav., 2004;81(1):5-13.
    Species: Guinea Pig
    Sample Types: Serum
  266. Regulation of Pseudomonas aeruginosa corneal infection in IL-1 beta converting enzyme (ICE, caspase-1) deficient mice.
    Authors: Thakur A, Barrett RP, McClellan S, Hazlett LD
    Curr. Eye Res., 2004;29(4):225-33.
    Species: Mouse
    Sample Types: Tissue Homogenates
  267. Suppression of graft coronary artery disease by a brief treatment with a selective epsilonPKC activator and a deltaPKC inhibitor in murine cardiac allografts.
    Authors: Tanaka M, Terry RD, Mokhtari GK, Inagaki K, Koyanagi T, Kofidis T, Mochly-Rosen D, Robbins RC
    Circulation, 2004;110(11):II194-9.
    Species: Mouse
    Sample Types: Tissue Homogenates
  268. The class A macrophage scavenger receptor attenuates CXC chemokine production and the early infiltration of neutrophils in sterile peritonitis.
    Authors: Cotena A, Platt N
    J. Immunol., 2004;173(10):6427-32.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  269. IL-1 receptor-associated kinase 1 mediates protection against Staphylococcus aureus infection.
    Authors: Verdrengh M, Thomas JA, Hultgren OH
    Microbes Infect., 2004;6(14):1268-72.
    Species: Mouse
    Sample Types: Serum
  270. Cytokine expression in experimental chronic otitis media with effusion in mice.
    Authors: Maeda K, Hirano T, Ichimiya I, Kurono Y, Suzuki M, Mogi G
    Laryngoscope, 2004;114(11):1967-72.
    Species: Mouse
    Sample Types: Tissue Secretion
  271. T cell-specific ablation of Fas leads to Fas ligand-mediated lymphocyte depletion and inflammatory pulmonary fibrosis.
    Authors: Hao Z, Hampel B, Yagita H, Rajewsky K
    J. Exp. Med., 2004;199(10):1355-65.
    Species: Mouse
    Sample Types: Serum
  272. Systemic up-regulation of sTNFR2 and IL-6 in Porphyromonas gingivalis pneumonia in mice.
    Authors: Petelin M, Naruishi K, Shiomi N, Mineshiba J, Arai H, Nishimura F, Takashiba S, Murayama Y
    Exp. Mol. Pathol., 2004;76(1):76-81.
    Species: Mouse
    Sample Types: Serum
  273. Increased interleukin-10 associated with low IL-6 concentration correlated with greater survival rates in mice infected by rabies virus vaccinated against it and immunomodulated with P. acnes.
    Authors: Megid J, Kaneno R, Nozaki CN, Brito CJ, Almeida MF
    Comp. Immunol. Microbiol. Infect. Dis., 2004;27(6):393-411.
    Species: Mouse
    Sample Types: Serum
  274. Thrombomodulin mutant mice with a strongly reduced capacity to generate activated protein C have an unaltered pulmonary immune response to respiratory pathogens and lipopolysaccharide.
    Authors: Rijneveld AW, Weijer S, Florquin S, Esmon CT, Meijers JC, Speelman P, Reitsma PH, ten Cate H, van der Poll T
    Blood, 2003;103(5):1702-9.
    Species: Mouse
    Sample Types: BALF
  275. Redundancy of a functional melanocortin 1 receptor in the anti-inflammatory actions of melanocortin peptides: studies in the recessive yellow (e/e) mouse suggest an important role for melanocortin 3 receptor.
    Authors: Getting SJ, Christian HC, Lam CW, Gavins FN, Flower RJ, Schioth HB, Perretti M
    J. Immunol., 2003;170(6):3323-30.
    Species: Mouse
    Sample Types: Peritoneal Fluid
  276. Interleukin-10 negatively regulates local cytokine and chemokine production but does not influence antibacterial host defense during murine pneumococcal meningitis.
    Authors: Zwijnenburg PJ, van der Poll T, Florquin S, Roord JJ, van Furth AM
    Infect. Immun., 2003;71(4):2276-9.
    Species: Mouse
    Sample Types: Tissue Homogenates
  277. IL-17, produced by lymphocytes and neutrophils, is necessary for lipopolysaccharide-induced airway neutrophilia: IL-15 as a possible trigger.
    Authors: Ferretti S, Bonneau O, Dubois GR, Jones CE, Trifilieff A
    J. Immunol., 2003;170(4):2106-12.
    Species: Mouse
    Sample Types: BALF
  278. Caspase-1-deficient mice have delayed neutrophil apoptosis and a prolonged inflammatory response to lipopolysaccharide-induced acute lung injury.
    Authors: Rowe SJ, Allen L, Ridger VC, Hellewell PG, Whyte MK
    J. Immunol., 2002;169(11):6401-7.
    Species: Mouse
    Sample Types: BALF
  279. Dendritic cells phagocytose and are activated by Treponema pallidum.
    Authors: Bouis DA, Popova TG, Takashima A, Norgard MV
    Infect. Immun., 2001;69(1):518-28.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  280. The protein tyrosine kinase inhibitor AG126 prevents the massive microglial cytokine induction by pneumococcal cell walls.
    Authors: Hanisch UK, Prinz M, Angstwurm K, Hausler KG, Kann O, Kettenmann H, Weber JR
    Eur. J. Immunol., 2001;31(7):2104-15.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  281. Amyloid beta and amylin fibrils induce increases in proinflammatory cytokine and chemokine production by THP-1 cells and murine microglia.
    Authors: Yates SL, Burgess LH, Kocsis-Angle J, Antal JM, Dority MD, Embury PB, Piotrkowski AM, Brunden KR
    J. Neurochem., 2000;74(3):1017-25.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  282. Sustained interleukin-1beta overexpression exacerbates tau pathology despite reduced amyloid burden in an Alzheimer's mouse model.
    Authors: Ghosh S, Wu M, Shaftel S, Kyrkanides S, Laferla F, Olschowka J, O'Banion M
    J Neurosci, 0;33(11):5053-64.
    Species: Mouse
    Sample Types: Tissue Homogenates
  283. Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors.
    Authors: Babelova A, Moreth K, Tsalastra-Greul W, Zeng-Brouwers J, Eickelberg O, Young MF, Bruckner P, Pfeilschifter J, Schaefer RM, Schaefer R, Grone HJ, Schaefer L
    J Biol Chem, 0;284(36):24035-48.
    Species: Mouse
    Sample Types: Plasma
  284. Neurokinin-1 receptor antagonism improves postoperative neurocognitive disorder in mice.
    Authors: Li Z, Luo T, Ning X, Xiong C, Wu A
    Neurosci Lett, 0;687(0):189-195.
    Species: Mouse
    Sample Types: Tissue Homogenates

FAQs

  1. Does the Mouse IL-1 beta/IL-1F2 Quantikine ELISA (Catalog # MLB00C) crosss-react with the pro-form of Mouse IL-1 beta?

    • The Mouse IL-1 beta/IL-1F2 Quantikine ELISA is designed to detect mature mouse IL-1 beta and the assay is calibrated against recombinant mouse IL-1 beta. It is possible that the kit also detects the pro-form, however, R&D Systems has not performed this characterization.

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Reviews for Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit

Average Rating: 4.8 (Based on 12 Reviews)

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Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit
By Anonymous on 07/26/2020
Application: Sample Tested: Bone marrow

Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit
By Anonymous on 02/11/2020
Application: Sample Tested: Mouse pancreas

Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit
By Anonymous on 10/17/2019
Application: Sample Tested: Brain (hypothalamus) tissue,Brainstem tissue

Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit
By Anonymous on 09/21/2019
Application: Sample Tested: Brain (hippocampus),Serum

Hippocampus: sensitivity is good for detection of samples with dilution not more than 4X.


Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit
By Anonymous on 06/20/2019
Application: Sample Tested: Embryonic cortical glial cells

Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit
By Anonymous on 05/22/2019
Application: Sample Tested: Mouse Lung BALF

Highly sensitive ELISA very easy to work with. Don't normally dilute samples.


Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit
By Anonymous on 04/10/2019
Application: Sample Tested: EDTA Plasma

Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit
By Anonymous on 03/12/2019
Application: Sample Tested: Serum

Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit
By Anonymous on 02/19/2019
Application: Sample Tested: Adult brain (hippocampus),Brain (cerebral cortex),Brain (hypothalamus) tissue,Striatum

One of the best ELISA kits for interleukin- 1 beta estimation. I have used kits from 2 other vendors but the reproducibility with this kit is uncomparable. I am blindly thinking of RnD systems from my ELISA requirements after using this kit.


Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit
By Anonymous on 05/08/2018
Application: Sample Tested: Heparin Plasma

Among best ELISAs I've worked with. Great consistency lot to lot, high sensitivity, easy to work with small amount of samples (usually dilute mouse plasma 1:10). Appropriate for concentration response curves.


Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit
By Anonymous on 12/04/2017
Application: Sample Tested: Cell culture supernatant

highly recommend.


Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit
By Anonymous on 03/07/2017
Application: Sample Tested: Cell culture supernatant,Mouse Primary Monocytes