Phospho-MEK1 (S218/S222)/MEK2 (S222/S226) Cell-Based ELISA

Name: Phospho-MEK1 (S218/S222)/MEK2 (S222/S226) Cell-Based ELISA
Brand: R&D Systems
SKU: KCB2506

Catalog #: KCB2506 Datasheet / COA / SDS

Discontinued Product

KCB2506 has been discontinued.

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Summary Product Datasheets Preparation and Storage Background

Phospho-MEK1 (S218/S222)/MEK2 (S222/S226) Cell-Based ELISA Summary

Alternatively

* Alternatively, this assay can be run over two days, which requires 2 hours 30 mins (day 1) and 4 hours (day 2).

* Provided that the recommended microplates, buffers, diluents, substrates and solutions are used, and the assay is run as summarized in the Assay Procedure provided.

Product Datasheets

Product Datasheet

COA

SDS

Preparation and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: MEK1/MEK2

MEK1 and MEK2, also known as MAP2K1 and MAP2K2, are activated in response to mitogenic stimuli. Activation occurs through dual phosphorylation at S218/S222 of MEK1 and S222/S226 of MEK2 by several upstream MAP3Ks. Both MEK1 and MEK2 are dual-specificity protein kinases, phosphorylating and activating ERK1 and ERK2 at Thr and Tyr positions.

Long Name:

Mitogen-activated Protein Kinase Kinase 1

Alternate Names:

CFC3; CFC4; dual specificity mitogen-activated protein kinase kinase 1; dual specificity mitogen-activated protein kinase kinase 2; ERK activator kinase 1; ERK activator kinase 2; MAP kinase kinase 2; MAPK/ERK kinase 1; MAPK/ERK kinase 2; MAPKK 1; MAPKK1; MAPKK2; MEK 1; MEK1; MEK1/MEK2; MEK2; MEL; mitogen-activated protein kinase kinase 2, p45; MKK1; MKK2; PRKMK1; PRKMK2; protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1)