Key Product Details

Species Reactivity

Multi-Species

Applications

Western Blot

Label

Biotin

Antibody Source

Monoclonal Mouse IgG1 Clone # 44922
View all TGF-beta 3 Primary Antibodies »

Product Specifications

Immunogen

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human TGF‑ beta 3
Ala301-Ser412 (Tyr340Phe)
Accession # NP_003230.1

Specificity

Detects TGF-beta 3 in Western blots. In Western blots, this antibody shows approximately 10% cross-reactivity with recombinant human (rh) TGF‑ beta 2, 5% with rhTGF‑ beta 1.2, and no cross-reactivity with rhTGF-alpha, rhTGF-beta 1, rhART, rhGDNF, rhLAP, rhNeuritin, or rhLefty.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for TGF-beta 3 Biotinylated Antibody

Application
Recommended Usage

Western Blot

1 µg/mL
Sample: Recombinant Human TGF-beta 3 (Catalog # 243-B3)
under non-reducing conditions only

Reviewed Applications

Read 1 review rated 4 using BAM643 in the following applications:

Formulation, Preparation, and Storage

Purification

Protein A or G purified from ascites

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: TGF-beta 3

TGF-beta 3 (transforming growth factor beta 3) Is a pleiotropic cytokine that regulates immune function, proliferation, and epithelial-mesenchymal transition. Disulfide-linked homodimers of LAP and TGF-beta 3 remain non-covalently associated after secretion, forming the small latent TGF-beta 3 complex. Covalent linkage of LAP to one of three latent TGF-beta binding proteins (LTBPs) creates a large latent complex that may interact with the extracellular matrix. Bioactive TGF-beta is released by proteolytic cleavage. TGF-beta 3 signals through a receptor complex containing TGF-beta RII and either TGF-beta RI/ALK5 or ALK1.

Long Name

Transforming Growth Factor beta 3

Alternate Names

ARVD1, LDS5, RNHF, TGFB3, TGFbeta 3

Entrez Gene IDs

7043 (Human); 21809 (Mouse); 25717 (Rat)

Gene Symbol

TGFB3

UniProt

NP_003230.1

Additional TGF-beta 3 Products

Product Documents for TGF-beta 3 Biotinylated Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for TGF-beta 3 Biotinylated Antibody

For research use only

Customer Reviews for TGF-beta 3 Biotinylated Antibody (1)

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  • TGF-beta 3 Biotinylated Antibody
    Name: Anonymous
    Application: ELISA
    Sample Tested: Purified protein
    Species: Human
    Verified Customer | Posted 03/15/2021
    Dose of TGFb3, detection w/ biotinylated Anti-TGFb3
    TGF-beta 3 Biotinylated Antibody BAM643

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