TGF-beta 3 Antibody
TGF-beta 3 Antibody Summary
Ala301-Ser412 (Tyr340Phe)
Accession # NP_003230.1
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Applications
under non-reducing conditions only
Human TGF-beta 3 Sandwich Immunoassay
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
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TGF-beta 3 in Human Heart. TGF-beta 3 was detected in immersion fixed paraffin-embedded sections of human heart using TGF-beta 3 Monoclonal Antibody (Catalog # MAB643) at 25 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Mouse HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS002) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: TGF-beta 3
The active form of TGF-beta 3 is a disulfide-linked homodimer which is generated by activation of the latent TGF-beta 3 complex. TGF-beta s are multifunctional cytokines that activate or repress multiple genes in a wide variety of cell types. Depending on the cell context, TGF-beta can control many cellular processes including growth, morphogenesis, and apoptosis.
Product Datasheets
Citations for TGF-beta 3 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 2
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Transforming growth factor beta expression in human placenta and placental bed during early pregnancy.
Authors: Simpson H, 2019, Robson SC, Bulmer JN, Barber A, Lyall F
6897, 2002;23(1):44-58.
Species: Human
Sample Types: Tissue Homogenates
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Differential TGFbeta pathway targeting by miR-122 in humans and mice affects liver cancer metastasis.
Authors: Yin S, Fan Y, Zhang H, Zhao Z, Hao Y, Li J, Sun C, Yang J, Yang Z, Yang X, Lu J, Xi J
Nat Commun, 0;7(0):11012.
Species: Human
Sample Types: Tissue Homogenates
Applications: Western Blot
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