116 results for "AMPK alpha 2" in Products
AMPK alpha 2 Products
AMP-activated protein kinase (AMPK) is a heterotrimeric complex consisting of a catalytic a subunit and regulatory beta and gamma subunits. Each subunit exists as alternate isoforms (alpha 1, alpha 2, beta 1, beta 2, gamma 1, gamma 2, gamma 3), with all 12 combinations capable of forming complexes. The catalytic a subunit of AMPK is activated allosterically by AMP and by phosphorylation via the AMPK kinase LKB1. Active AMPK downregulates anabolic pathways such as fatty acid, triglyceride, and cholesterol synthesis, and up-regulates catabolic pathways such as glycolysis and fatty acid oxidation. AMPK's role in metabolic regulation has implicated this serine/threonine kinase as a therapeutic target in heart disease, obesity, and diabetes.
Potent AMPK inhibitor; also BMP type I receptor inhibitor
| Alternate Names: | Compound C,BML-275 |
| Chemical Name: | 6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)-pyrazolo[1,5-a]pyrimidine dihydrochloride |
| Purity: | ≥98% |
Contains 4 sets of 2 membranes - each spotted in duplicate with antibodies against 37 different kinases and 2 related total proteins
| Reactivity: | Human |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, Simple Western |
Potent AMPK activator
| Chemical Name: | 6,7-Dihydro-4-hydroxy-3-(2'-hydroxy[1,1'-biphenyl]-4-yl)-6-oxo-thieno[2,3-b]pyridine-5-carbonitrile |
| Purity: | ≥98% |
Activator of LKB1/AMPK; antidiabetic agent
| Chemical Name: | N,N-Dimethylimidodicarbonimidic diamide hydrochloride |
AMPK activator
| Chemical Name: | N1-(β-D-Ribofuranosyl)-5-aminoimidazole-4-carboxamide |
| Purity: | ≥99% |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #847123 |
| Applications: | WB, ICC/IF, Simple Western |
| Reactivity: | Human, Monkey |
| Details: | Mouse IgG1 Monoclonal Clone #8E11H5 |
| Applications: | IHC, WB, ELISA, Flow |
![Western Blot: AMPK alpha 2 Antibody (8E11H5)BSA Free [NBP2-61852]](https://resources.rndsystems.com/images/products/AMPK-alpha-2-Antibody-8E11H5-Western-Blot-NBP2-61852-img0006.jpg "Western Blot: AMPK alpha 2 Antibody (8E11H5)BSA Free [NBP2-61852]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
![Western Blot: AMPK alpha 2 Antibody [NB100-238]](https://resources.rndsystems.com/images/products/AMPK-alpha-2-Antibody-Western-Blot-NB100-238-img0005.jpg "Western Blot: AMPK alpha 2 Antibody [NB100-238]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: AMPK alpha 2 Antibody [NBP2-38532]](https://resources.rndsystems.com/images/products/AMPK-alpha-2-Antibody-Western-Blot-NBP2-38532-img0002.jpg "Western Blot: AMPK alpha 2 Antibody [NBP2-38532]")
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #1G8 |
| Applications: | WB, ELISA, ICC/IF, Func, Mycoplasma |
![Western Blot: AMPK alpha 2 Antibody (1G8) [H00005563-M02]](https://resources.rndsystems.com/images/products/AMPK-alpha-2-Antibody-1G8-Western-Blot-H00005563-M02-img0009.jpg "Western Blot: AMPK alpha 2 Antibody (1G8) [H00005563-M02]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: AMPK alpha 2 Antibody [NBP1-56322]](https://resources.rndsystems.com/images/products/AMPK-alpha-2-Antibody-Western-Blot-NBP1-56322-img0004.jpg "Western Blot: AMPK alpha 2 Antibody [NBP1-56322]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #5B4G1 |
| Applications: | IHC, WB, ELISA |
![Western Blot: AMPK alpha 2 Antibody (5B4G1)BSA Free [NBP2-61853]](https://resources.rndsystems.com/images/products/AMPK-alpha-2-Antibody-5B4G1-Western-Blot-NBP2-61853-img0004.jpg "Western Blot: AMPK alpha 2 Antibody (5B4G1)BSA Free [NBP2-61853]")
Potent ATP-competitive Src family kinase inhibitor; also AMPK inhibitor; cell permeable
| Chemical Name: | 2,3-Dihydro-N,N-dimethyl-2-oxo-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylene]-1H-indole-5-sulfonamide |
| Purity: | ≥95% |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA |
![Western Blot: AMPK alpha 2 Antibody [NBP1-49859]](https://resources.rndsystems.com/images/products/AMPK-alpha-2-Antibody-Western-Blot-NBP1-49859-img0005.jpg "Western Blot: AMPK alpha 2 Antibody [NBP1-49859]")
| Reactivity: | Human |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #4F4 |
| Applications: | WB, ELISA, ICC/IF |
![AMPK alpha 2 [p Thr172] Antibody (4F4)](https://resources.rndsystems.com/images/products/nbp3-26400_rabbit-ampk-alpha-2-p-thr-172-mab-4f4-282202411363013.jpg "Western Blot: AMPK alpha 2 [p Thr172] Antibody (4F4) [NBP3-26400] -")