146 results for "Calcium-sensing R/CaSR" in Products
Calcium-sensing R/CaSR Products
Calcium-Sensing Receptor (CaSR) is a member of the G protein-coupled receptor family. CaSR is an integral membrane protein that senses changes in the extracellular concentration of calcium ions and controls the release of parathyroid hormone. The activity of the calcium-sensing receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system.
Mutations that inactivate CaSR lead to familial hypocalciuric hypercalcemia, whereas mutations that activate CaSR cause autosomal dominant hypocalcemia. Calcium-Sensing Receptor antibodies are useful tools for parathyroid studies and research on cellular calcium homeostasis regulation.
| Reactivity: | Human, Mouse, Rat, Porcine, Bovine |
| Details: | Mouse IgG2A Monoclonal Clone #5C10, ADD |
| Applications: | IHC, WB, ELISA, ICC/IF |
![Western Blot: Calcium-sensing R/CaSR Antibody (5C10, ADD)BSA Free [NB120-19347]](https://resources.rndsystems.com/images/products/Calcium-sensing-R-CaSR-Antibody-5C10-ADD-Western-Blot-NB120-19347-img0014.jpg "Western Blot: Calcium-sensing R/CaSR Antibody (5C10, ADD)BSA Free [NB120-19347]")
| Reactivity: | Human, Mouse, Rat, Rabbit |
| Details: | Mouse IgG1 kappa Monoclonal Clone #HL 1499 |
| Applications: | WB, ELISA, Flow, Simple Western, IP, + 1 More |
![Western Blot: Calcium-sensing R/CaSR Antibody (HL 1499)BSA Free [NB100-1830]](https://resources.rndsystems.com/images/products/Calcium-sensing-R-CaSR-Antibody-HL-1499-Western-Blot-NB100-1830-img0012.jpg "Western Blot: Calcium-sensing R/CaSR Antibody (HL 1499)BSA Free [NB100-1830]")
| Reactivity: | Human, Mouse, Rat, Rabbit |
| Details: | Mouse IgG1 kappa Monoclonal Clone #HL 1499 |
| Applications: | IHC, WB, ELISA, Flow, ICC/IF, + 3 More |
![Western Blot: Calcium-sensing R/CaSR Antibody (HL 1499)Azide and BSA Free [NBP2-80607]](https://resources.rndsystems.com/images/products/Calcium-sensing-R-CaSR-Antibody-HL-1499-Azide-and-BSA-Free-Western-Blot-NBP2-80607-img0002.jpg "Western Blot: Calcium-sensing R/CaSR Antibody (HL 1499)Azide and BSA Free [NBP2-80607]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Immunohistochemistry-Paraffin: Calcium-sensing R/CaSR Antibody [NBP2-38622]](https://resources.rndsystems.com/images/products/Calcium-sensing-R-CaSR-Antibody-Immunohistochemistry-Paraffin-NBP2-38622-img0013.jpg "Immunohistochemistry-Paraffin: Calcium-sensing R/CaSR Antibody [NBP2-38622]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: Calcium-sensing R/CaSR Antibody [NBP1-84687]](https://resources.rndsystems.com/images/products/Calcium-sensing-R-CaSR-Antibody-Western-Blot-NBP1-84687-img0005.jpg "Western Blot: Calcium-sensing R/CaSR Antibody [NBP1-84687]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat, Feline |
| Details: | Rabbit IgG Monoclonal Clone #HL2357 |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
Positive allosteric modulator of human calcium-sensing receptor (CaSR)
| Chemical Name: | 2-Chloro-N-[(1R)-1-(3-methoxyphenyl)ethyl]-benzenepropanamine hydrochloride |
| Purity: | ≥98% |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #611825 |
| Applications: | Flow, CyTOF-ready |
Selective calcium-sensing receptor (CaSR) antagonist; orally active calcilytic agent
| Chemical Name: | 2-Chloro-6-[(2R)-3-[[1,1-dimethyl-2-(2-naphthalenyl)ethyl]amino-2-hydroxypropoxy]benzonitrile hydrochloride |
| Purity: | ≥98% |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #PSH03-47 |
| Applications: | IHC, WB |
Negative allosteric modulator of calcium-sensing receptor (CaSR)
| Chemical Name: | 4-Chloro-N-[(1S,2S)-2-[[(1R)-1-(1-naphthalenyl)ethyl]amino]cyclohexyl]-benzamide hydrochloride |
| Purity: | ≥98% |
Biased allosteric modulator of calcium-sensing receptor (CaSR)
| Chemical Name: | α-(2,4-Dimethylphenyl)-α-methyl-2-benzothiazolemethanol |
| Purity: | ≥98% |
Allosteric Calcium-sensing receptor (CaSR) agonist; also CYP2D2 inhibitor and Ca2+ channel blocker; orally bioavailable
| Alternate Names: | AMG 073 |
| Chemical Name: | N-[(1R)-1-(1-Naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine hydrochloride |
| Purity: | ≥98% |
| Reactivity: | Human |
| Source: | HEK293 |
| Accession #: | P41180-1 |
| Reactivity: | Human |
| Reactivity: | Human |
| Applications: | WB |
![Western Blot: Calcium-sensing R/CaSR Overexpression Lysate [NBL1-08721]](https://resources.rndsystems.com/images/products/Calcium-Sensing-Receptor-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-08721-img0002.jpg "Western Blot: Calcium-sensing R/CaSR Overexpression Lysate [NBL1-08721]")
| Reactivity: | Human |
| Sensitivity: | 0.47 ng/mL |
| Assay Range: | 0.78 - 50 ng/mL |
| Applications: | ELISA |
| Reactivity: | Mouse |
| Sensitivity: | 0.10 ng/mL |
| Assay Range: | 0.16 - 10 ng/mL |
| Applications: | ELISA |
| Reactivity: | Rat |
| Sensitivity: | 0.10 ng/mL |
| Assay Range: | 0.16 - 10 ng/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #611825 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #611825 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #611825 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #611825 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #611825 |
| Applications: | Flow |