9 results for "CHRM1 Small Molecules and Peptides" in Products
CHRM1 Small Molecules and Peptides
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13.
Non-selective cholinergic agonist
| Alternate Names: | Carbachol |
| Chemical Name: | (2-Hydroxyethyl)trimethylammonium chloride carbamate |
Muscarinic agonist
| Chemical Name: | (3S-cis)-3-Ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-2(3H)-furanone hydrochloride |
| Purity: | ≥98% |
Functionally biased muscarinic M4 receptor agonist
| Chemical Name: | 3-[4-(Hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methylpyridine oxalate |
| Purity: | ≥98% |
Potent, selective M1 antagonist
| Chemical Name: | 4,9-Dihydro-3-methyl-4-[(4-methyl-1-piperazinyl)acetyl]-10H-thieno[3,4-b][1,5]benzodiazepin-10-one dihydrochloride |
| Purity: | ≥98% |
Muscarinic agonist
| Chemical Name: | 1-[4-(1-Pyrrolidinyl)-2-butynyl]-2-pyrrolidinone sesquifumarate |
| Purity: | ≥98% |
Selective M1 muscarinic agonist
| Chemical Name: | 4-[[[(3-Chlorophenyl)amino]carbonyl]oxy]-N,N,N-trimethyl-2-butyn-1-aminium chloride |
| Purity: | ≥99% |
Selective M1 agonist
| Alternate Names: | AF 102B,SNI 2011 |
| Chemical Name: | cis-2-Methylspiro[1,3-oxathiolane-5,3'-quinuclidine] hydrochloride |
Positive allosteric modulator of M1 receptors
| Chemical Name: | 4-[[2-[(2-Methylbenzoyl)amino]ethyl]amino]-1-piperidinecarboxylic acid ethyl ester hydrochloride |
| Purity: | ≥98% |
Highly selective M1 antagonist
| Chemical Name: | N-[3-Oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide |
| Purity: | ≥98% |
