9 results for "Compounds for NSC Differentiation" in Products

Compounds for NSC Differentiation

Neural Stem Cells Differentiation

Neuronal differentiation is guided by key signaling pathways including Wnt, BMP, FGF and retinoic acid (RA) signaling cascades. The generation of neural progenitors is characterized by expression of neuroepithelial markers, such as nestin, PAX6, SOX1, SOX3, PSA-NCAM and MUSASHI-1 in vitro, and the formation of neural rosettes, reminiscent of neural tube initiation in vivo. Various methods have been developed for the conversion of induced pluripotent stem cells ...

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Potent and selective ALK2 and ALK3 inhibitor; inhibits BMP4 signaling; promotes neural induction of hPSCs

GMP Version Available: TB6053-GMP
GMP
Chemical Name: 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride
Purity: ≥98%
Application of LDN 193189 in motor neurons differentiated from iPSCs
(2)
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Selective ALK2 inhibitor

Chemical Name: 4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline
Purity: ≥98%
Selective ALK2 inhibitor
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γ-secretase inhibitor; induces neuronal differentiation

Alternate Names: γ-Secretase Inhibitor XXI
Chemical Name: N-[(1S)-2-[[(3S)-2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluorobenzeneacetamide
Purity: ≥98%
γ-secretase inhibitor; induces neuronal differentiation
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PDE inhibitor (non-selective)

Chemical Name: 3,7-Dihydro-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione
Purity: ≥98%
PDE inhibitor (non-selective)
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FGFR1 and -3 inhibitor

Chemical Name: N-[2-[[4-(Diethylamino)butyl]amino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)urea
Purity: ≥98%
FGFR1 and -3 inhibitor
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Histone deacetylase inhibitor

Alternate Names: VPA,Sodium Valproate
Chemical Name: Sodium 2-propylpentanoate
Histone deacetylase inhibitor
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5-HT reuptake inhibitor

Chemical Name: N-Methyl-3-[(4-trifluoromethyl)phenoxy]-3-phenylpropylamine hydrochloride
Purity: ≥98%
5-HT reuptake inhibitor
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Potent GSK3 inhibitor; induces neuronal and CD8(+) T cell differentiation

Chemical Name: 3-[[6-(3-Aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenol
Purity: ≥97%
Potent GSK3 inhibitor; induces neuronal and CD8(+) T cell differentiation
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Tankyrase (AKA PARP5) inhibitor; used to generate neurons from epiblast stem cells

Chemical Name: N-(Cyclopropylmethyl)-4-(4-methoxybenzoyl)-N-[(3,5,7,8-tetrahydro-4-oxo-4H-pyrano[4,3-d]pyrimidin-2-yl)methyl]-1-piperidineacetamide
Purity: ≥98%
Tankyrase (AKA PARP5) inhibitor; used to generate neurons from epiblast stem cells
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