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881 results for "CTLA-4" in Products
CTLA-4 Products
CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.
| Reactivity: | Human |
| Source: | Sf 21 (baculovirus) |
| Accession #: | Q6GR94 |
| Applications: | Bioactivity |
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| Reactivity: | Human |
| Source: | CHO |
| Accession #: | P16410 |
| Applications: | Bioactivity |
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| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Flow, ICC/IF, CyTOF-ready |
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| Reactivity: | Mouse |
| Source: | NS0 |
| Accession #: | Q6GTR6 |
| Applications: | Bioactivity |
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| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #BNI3 |
| Applications: | IHC, ELISA, Flow, ICC/IF, IP |
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| Reactivity: | Mouse |
| Details: | Rat IgG2A Monoclonal Clone #63828 |
| Applications: | WB, B/N, Flow, CyTOF-ready |
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| Reactivity: | Human |
| Sensitivity: | 0.13 pg/mL |
| Assay Range: | 0.781-50 pg/mL (Cell Culture Supernates, Cell Lysates, Serum, EDTA Plasma, Heparin Plasma, Urine) |
| Applications: | ELISA |
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| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA(Cap) |
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| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #Hu111 |
| Applications: | Flow, CyTOF-ready |
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| Reactivity: | Mouse |
| Assay Range: | 125-8000 pg/mL |
| Applications: | ELISA |
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