8 results for "Cytochrome P450 Inhibitors" in Products

Cytochrome P450 Inhibitors

Cytochrome P450 (CYP450) enzymes are a diverse group of catalysts that contains 57 members in humans. CYPs are usually membrane-bound and are localized to the inner mitochondrial or endoplasmic reticular membrane. CYPs have oxygenase activity and commonly catalyze redox reactions, involving the oxidation of the substrate and reduction of water. This group of enzymes contain a heme iron within the active site, which is essential for catalytic activity.

CYPs have been found in all organisms ...

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Cytochrome P450c17 inhibitor

Chemical Name: cis-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl] methoxy]phenyl]piperazine
Purity: ≥98%
Cytochrome P450c17 inhibitor
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11-β hydroxylase inhibitor

Chemical Name: 2-Methyl-1,2-di-3-pyridinyl-1-propanone
Purity: ≥98%
11-β hydroxylase inhibitor
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Potent, reversible non-steroidal aromatase inhibitor

Alternate Names: CGS 20267
Chemical Name: 4,4'-(1H-1,2,4-Triazol-1-ylmethylene)bisbenzonitrile
Purity: ≥98%
Potent, reversible non-steroidal aromatase inhibitor
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Blocks retinoic acid metabolism

Alternate Names: R-75251
Chemical Name: 5-[(3-Chlorophenyl)-1H-imidazol-1-ylmethyl]-1H-benzimidazole dihydrochloride
Purity: ≥98%
Blocks retinoic acid metabolism
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Cytochrome P450 inhibitor; antifungal

Alternate Names: CLT
Chemical Name: 1-(2-Chloro-α,α-diphenylbenzyl)imidazole
Purity: ≥98%
Cytochrome P450 inhibitor; antifungal
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CYP17 inhibitor; also androgen receptor antagonist

Alternate Names: TOK-001,VN/124-1
Chemical Name: (3β)-17-(1H-Benzimidazol-1-yl)androsta-5,16-dien-3-ol
Purity: ≥98%
CYP17 inhibitor; also androgen receptor antagonist
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Allosteric Calcium-sensing receptor (CaSR) agonist; also CYP2D2 inhibitor and Ca2+ channel blocker; orally bioavailable

Alternate Names: AMG 073
Chemical Name: N-[(1R)-1-(1-Naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine hydrochloride
Purity: ≥98%
Allosteric Calcium-sensing receptor (CaSR) agonist; also CYP2D2 inhibitor and Ca2+ channel blocker; orally bioavailable
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Potent CYP17A1 inhibitor

Chemical Name: (3β)-17-(3-Pyridinyl)androsta-5,16-dien-3-yl acetate
Purity: ≥98%
Potent CYP17A1 inhibitor
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