8 results for "DNA, RNA and Protein Synthesis Inhibitors" in Products

DNA, RNA and Protein Synthesis Inhibitors

RNA, DNA and protein synthesis are fundamental processes necessary for all life.

RNA synthesis (transcription) begins by uncoiling a section of DNA that will be used as the template. RNA polymerase binds to a promoter sequence and initiates separation of the DNA double helix. Complementary ribonucleotides align and RNA polymerase catalyzes their polymerization. The newly synthesized RNA strand undergoes post-transcriptional processing before it leaves the nucleus.

Protein synthesis ...

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DNA cross-linking antitumor agent

Alternate Names: Ametycine
Chemical Name: [1aS-(1aα,8β,8aα,8bα)]-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione
Purity: ≥98%
DNA cross-linking antitumor agent
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DNA cross-linking antitumor agent

Alternate Names: Eloxatin
Chemical Name: Oxalato[(1R-trans)-1,2-cyclohexanediamine]platinum(II)
Purity: ≥98%
DNA cross-linking antitumor agent
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DNA cross-linking antitumor agent

Alternate Names: NSC 241240,Paraplatin,JM 8
Chemical Name: cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II)
Purity: ≥98%
DNA cross-linking antitumor agent
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Inhibits RNAPII-mediated transcription; antitumor, anti-inflammatory and immunosuppressive

Chemical Name: (3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)-3b,4,4a,6,6a,7a,7b,8b,9,10-Decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1(3H)-one
Purity: ≥98%
Inhibits RNAPII-mediated transcription; antitumor, anti-inflammatory and immunosuppressive
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Inhibits eIF4E:eIF4G subunit interaction

Chemical Name: α-[2-[4-(3,4-Dichlorophenyl)-2-thiazolyl]hydrazinylidene]-2-nitro-benzenepropanoic acid
Purity: ≥98%
Inhibits eIF4E:eIF4G subunit interaction
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Blocks eIF4E activity; antiviral guanosine analog

Chemical Name: 1-β-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide
Purity: ≥98%
Blocks eIF4E activity; antiviral guanosine analog
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Thymidine analog for labeling DNA; can be linked to a fluorophore by click chemistry

Chemical Name: 5-ethynyl-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
Purity: ≥95%
Thymidine analog for labeling DNA; can be linked to a fluorophore by click chemistry
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Prodrug of antiviral nucleoside analog; inhibits SARS-CoV, SARS-CoV-2 and MERS-CoV infection

Chemical Name: β-D-N4-hydroxycytidine-5'-isopropyl ester
Purity: ≥98%
Prodrug of antiviral nucleoside analog; inhibits SARS-CoV, SARS-CoV-2 and MERS-CoV infection
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