13 results for "ESC and iPSC Culture Kits and Reagents Small Molecules and Peptides" in Products

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ESC and iPSC Culture Kits and Reagents Small Molecules and Peptides

Y-27632 dihydrochloride

Catalog #: 1254
(19)
Citations (1710)
Product Documents

Selective ROCK inhibitor; inhibits ROCK1 (p160 ROCK) and ROCK2; stem cell freezing (cryopreservation) media component

GMP Version Available: TB1254-GMP
GMP
Alternate Names: y27632,Y-27632 2HCl,ROCK inhibitor,ROCK1 inhibitor
Chemical Name: trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride
Purity: ≥98%
ROCK inhibition by Y-27632 and immunostaining of skeletal myogenic differentiation of MESP1+ mesoderm,
(8)

A 83-01

Catalog #: 2939
(12)
Citations (1068)
Product Documents

Selective inhibitor of TGF-βRI, ALK4 and ALK7

Chemical Name: 3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide
Purity: ≥98%
Adult Stem Cell-derived Liver Organoids
(6)

IWP 2

Catalog #: 3533
(3)
Citations (520)
Product Documents

PORCN inhibitor; inhibits Wnt processing and secretion

Chemical Name: N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-acetamide
Purity: ≥98%
iPSC-derived heart organoids differentiated with IWP 2 and CHIR 99021
(2)

LY 294002 hydrochloride

Catalog #: 1130
(7)
Citations (107)
Product Documents

Prototypical PI 3-kinase inhibitor; also inhibits other kinases

Chemical Name: 2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one hydrochloride
Purity: ≥99%
Prototypical PI 3-kinase inhibitor; also inhibits other kinases

PD 98059

Catalog #: 1213
(5)
Citations (569)
Product Documents

MEK inhibitor

Chemical Name: 2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one
Purity: ≥98%
MEK inhibitor

SB 216763

Catalog #: 1616
Citations (263)
Product Documents

Potent, selective GSK-3 inhibitor

Chemical Name: 3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione
Purity: ≥98%
Potent, selective GSK-3 inhibitor

Pifithrin-α hydrobromide

Catalog #: 1267
(3)
Citations (14)
Product Documents

p53 inhibitor. Also aryl hydrocarbon receptor agonist

Chemical Name: 1-(4-Methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)ethanone hydrobromide
p53 inhibitor. Also aryl hydrocarbon receptor agonist

CKI 7 dihydrochloride

Catalog #: 5329
Citations (2)
Product Documents

CK1 inhibitor

Chemical Name: N-(2-Aminoethyl)-5-chloro-8-isoquinolinesulfonamide dihydrochloride
Purity: ≥99%
CK1 inhibitor

BIO

Catalog #: 3194
Citations (79)
Product Documents

Potent GSK-3 inhibitor; also inhibits cdks

Alternate Names: 6BIO
Chemical Name: (2'Z,3'E)-6-Bromoindirubin-3'-oxime
Purity: ≥98%
Potent GSK-3 inhibitor; also inhibits cdks

IWP 4

Catalog #: 5214
(1)
Citations (54)
Product Documents

Potent inhibitor of Wnt/β-catenin signaling

Chemical Name: N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-3-(2-methoxyphenyl)-4-oxothieno[3,2-d]pyrimidin-2-yl)thio]-acetamide
Purity: ≥98%
Potent inhibitor of Wnt/β-catenin signaling

PluriSln 1

Catalog #: 4847
Product Documents

SCD-1 inhibitor

Alternate Names: NSC 14613
Chemical Name: 4-Pyridinecarboxylic acid 2-phenylhydrazide
Purity: ≥99%
SCD-1 inhibitor

Y-27632 in solution

Catalog #: 7000
(1)
Product Documents

Sterile-filtered 10 mM solution of Y-27632, selective ROCK inhibitor, pre-dissolved in water

Chemical Name: trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride
Purity: ≥97%
vial of Y-27632 in solution
(2)

Retinoic acid

Catalog #: TB0695-RMU
Product Documents

Retinoic acid synthesized to Ancillary Material Grade

Chemical Name: 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2E,4E,6E,8E-nonatetraenoic acid
Purity: ≥98%
Retinoic acid synthesized to Ancillary Material Grade
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