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Selective ROCK inhibitor; inhibits ROCK1 (p160 ROCK) and ROCK2; stem cell freezing (cryopreservation) media component
Selective inhibitor of TGF-βRI, ALK4 and ALK7
PORCN inhibitor; inhibits Wnt processing and secretion
Prototypical PI 3-kinase inhibitor; also inhibits other kinases
Potent inhibitor of Wnt/β-catenin signaling
Potent, selective GSK-3 inhibitor
p53 inhibitor. Also aryl hydrocarbon receptor agonist
Potent GSK-3 inhibitor; also inhibits cdks
Rho/SRF pathway inhibitor; induces intermediate mesoderm differentiation from ESCs