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106 results for "FXR/NR1H4" in Products
FXR/NR1H4 Products
FXR and LXR fall into a category of proteins termed orphan receptors; because of their lack of a defined function, and in the case of LXR, the lack of a defined ligand. FXR has been shown to bind a class of lipid molecules called farnesoids. LXR/RXR heterodimers have highest affinity for DR-4 DNA elements while FXR/RXR heterodimers bind IR-1 elements. Both LXR/RXR and FXR/RXR heterodimers retain their responsiveness to 9-cis retinoic acid. The steroid receptor superfamily acts through direct ...
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #A9033A |
| Applications: | IHC, WB, ELISA, IP |
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| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
![Western Blot: FXR/NR1H4 Antibody [NB400-153]](https://resources.rndsystems.com/images/products/FXR-NR1H4-Antibody-Western-Blot-NB400-153-img0006.jpg "Western Blot: FXR/NR1H4 Antibody [NB400-153]")
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| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, Simple Western |
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| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 kappa Monoclonal Clone #1B10 |
| Applications: | WB, ELISA, ICC/IF |
![Western Blot: FXR/NR1H4 Antibody (1B10) [H00009971-M02]](https://resources.rndsystems.com/images/products/FXR-NR1H4-Antibody-1B10-Western-Blot-H00009971-M02-img0007.jpg "Western Blot: FXR/NR1H4 Antibody (1B10) [H00009971-M02]")
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| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI4F12 |
| Applications: | IHC, WB |
![Western Blot: FXR/NR1H4 Antibody (OTI4F12) [NBP2-46221]](https://resources.rndsystems.com/images/products/FXR-NR1H4-Antibody-4F12-Western-Blot-NBP2-46221-img0004.jpg "Western Blot: FXR/NR1H4 Antibody (OTI4F12) [NBP2-46221]")
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| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | ELISA, Flow, ICC/IF |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI4F12 |
| Applications: | IHC, WB |
![Western Blot: FXR/NR1H4 Antibody (OTI4F12)Azide and BSA Free [NBP2-71526]](https://resources.rndsystems.com/images/products/FXR-NR1H4-Antibody-OTI4F12-Azide-and-BSA-Free-Western-Blot-NBP2-71526-img0001.jpg "Western Blot: FXR/NR1H4 Antibody (OTI4F12)Azide and BSA Free [NBP2-71526]")
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| Reactivity: | Human |
| Applications: | AC |
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| Reactivity: | Human |
| Source: | Wheat germ |
| Applications: | WB, ELISA, AP, MA |
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| Reactivity: | Human |
| Applications: | WB |
![Western Blot: FXR/NR1H4 Overexpression Lysate [NBL1-13769]](https://resources.rndsystems.com/images/products/FXR-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-13769-img0002.jpg "Western Blot: FXR/NR1H4 Overexpression Lysate [NBL1-13769]")
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| Reactivity: | Human |
| Sensitivity: | 0.067 ng/mL (example only; lot dependent) |
| Assay Range: | 0.156 - 10 ng/mL (example only; lot dependent) |
| Applications: | ELISA |
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| Reactivity: | Human |
| Sensitivity: | 0.067 ng/mL (example only; lot dependent) |
| Assay Range: | 0.156 - 10 ng/mL (example only; lot dependent) |
| Applications: | ELISA |
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Selective farnesoid X receptor (FXR) agonist
| Chemical Name: | 3-[2-[2-Chloro-4-[[3-(2,6-dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methoxy]phenyl]ethenyl]benzoic acid |
| Purity: | ≥97% |
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Potent, selective farnesoid X receptor (FXR) agonist
| Chemical Name: | 3-[3-[(Cyclohexylcarbonyl)-[[4'-(dimethylamino)-[1,1'-biphenyl]-4-yl]methyl]amino]phenyl]-2-propenoic acid methyl ester |
| Purity: | ≥97% |
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| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
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| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
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| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
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| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
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| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
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| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
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| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
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| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
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Potent FXR antagonist
| Chemical Name: | 1-[(3-Methoxyphenyl)methyl]-N-[4-methyl-3-(4-morpholinylsulfonyl)phenyl]-3-(4-methylphenyl)-1H-pyrazole-4-carboxamide |
| Purity: | ≥98% |
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| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
![FXR/NR1H4 Antibody [CoraFluor™ 1]](https://resources.rndsystems.com/images/products/nb400-153cl1_rabbit-fxr-nr1h4-pab-corafluor-1-10920251141298.png "Product Feature: CoraFluor Probes for TR-FRET")
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