Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all FXR/NR1H4 Primary Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human FXR/NR1H4
Leu211-Gln486
Accession # Q96RI1

Specificity

Detects human FXR/NR1H4 in direct ELISAs and Western blots.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Human FXR/NR1H4 Antibody

Application
Recommended Usage

Western Blot

0.1 µg/mL
Sample: Recombinant Human FXR/NR1H4

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: FXR/NR1H4

FXR is a 56 kDa nuclear receptor belonging to the NR1 subfamily. It is highly expressed in liver, intestine, kidney and white adipose tissue. FXR binds bile acids and functions as a transcription activator or repressor through interactions with a large variety of FXR response elements. Human and mouse FXR share approximately 92% amino acid sequence identity.

Long Name

Farnesoid X-activated receptor

Alternate Names

BAR, HRR-1, NR1H4, RIP14

Entrez Gene IDs

9971 (Human); 20186 (Mouse); 60351 (Rat)

Gene Symbol

NR1H4

UniProt

Q96RI1

Additional FXR/NR1H4 Products

Product Documents for Human FXR/NR1H4 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Download SDS

Product Specific Notices for Human FXR/NR1H4 Antibody

For research use only

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FAQs

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