IkB Kinase Inhibitors: Products

The classical active IKK complex, composed of IKK alpha, IKK beta, and two forms of processed IKK gamma, phosphorylates and inactivates IkB, resulting in the release and nuclear translocation of active NFkB. The regulatory IKK gamma is required for activation of the IKK complex.

"IkB Kinase Inhibitors" has 14 results in Products.
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Nrf2 pathway activator; also NF-κB pathway inhibitor; inhibits IKKβ

TPCA-1 

Potent, selective inhibitor of IKKβ

ACHP 

Selective IKKα and IKKβ inhibitor

BMS 345541 

Selective allosteric inhibitor of IKK; anti-inflammatory

IKK 16 

Selective inhibitor of IKK

IMD 0354 

Inhibitor of IKKβ; also exhibits antibacterial activity

SC 514 

IKKβ inhibitor; attenuates NF-κB-induced gene expression

PF 184 

Potent and selective IKKβ inhibitor

PS 1145 dihydrochloride 

Selective IKK inhibitor; orally active

Amlexanox 

Selective inhibitor of TBK

ML 120B dihydrochloride 

Novel IKK2-selective inhibitor

MRT 67307 dihydrochloride 

Salt inducible kinase (SIK) inhibitor

BI 605906 

Selective IKKβ inhibitor

GSK 319347A 

Potent and selective IKKε inhibitor
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