Proteome Profiler Mouse Cytokine Array Kit, Panel A

Name: Proteome Profiler Mouse Cytokine Array Kit, Panel A
Brand: R&D Systems
Rating: 4.6 (7 reviews)

Contains 4 membranes - each spotted in duplicate with 40 different cytokine antibodies

(133 citations)

(7 Reviews)

Kit Summary

A membrane-based antibody array for the parallel determination of the relative levels of selected mouse cytokines and chemokines. Validated for analyte detection in cell culture supernates, cell lysates, tissue lysates, serum, and plasma.

Key Benefits

Detects 40 mouse cytokines, chemokines, and acute phase proteins simultaneously
Requires no specialized equipment
Compatible with LI-COR and chemiluminescence detection

ARY006 Data Examples
View Data Examples

LI-COR Data Examples for Mouse Cytokine Array, Panel A

Principle of the Assay

The Proteome Profiler Mouse Cytokine Array Kit, Panel A is a membrane-based sandwich immunoassay. Samples are mixed with a cocktail of biotinylated detection antibodies (Step 1) and then incubated with the array membrane which is spotted in duplicate with capture antibodies to specific target proteins (Step 2). Captured proteins are visualized using chemiluminescent detection reagents (Step 3). The signal produced is proportional to the amount of analyte bound.

Why Use an Antibody Array to Detect Multiple Cytokines?

Determining the expression of multiple cytokines in a single sample can be expensive, time consuming and can require specialized equipment. Performing multiple immunoprecipitations and Western blots requires time, labor, and reagents. The use of a multiplex antibody array to detect multiple cytokines in a single sample can be cost-effective and also save time and sample.

Kit Contents

Rectangular 4-Well Multi-dish
4 Mouse Cytokine Array, Panel A nitrocellulose membranes spotted with 40 different antibodies to mouse cytokines, chemokines, and acute phase proteins
Array Buffer 4
Array Buffer 6
Chemi Reagent 1
Chemi Reagent 2
Detection Antibody Cocktail, Mouse Cytokine Array, Panel A
Streptavidin-HRP
Transparency Overlay Template
Wash Buffer Concentrate (25X)

For a complete list of the kit contents and necessary materials, please see the Materials Provided/Other Supplies Required sections of the product datasheet.

Stability and Storage

Store the unopened kit at 2 ^°C to 8 ^°C. Do not use past kit expiration date.

Simultaneously detect the levels of these cytokines, chemokines, and acute phase proteins in a single sample.
CXCL13/BLC/BCA-1	IL-5	M-CSF
C5a	IL-6	CCL2/JE/MCP-1
G-CSF	IL-7	CCL12/MCP-5
GM-CSF	IL-10	CXCL9/MIG
CCL1/I-309	IL-12 p70	CCL3/MIP-1 alpha
CCL11/Eotaxin	IL-13	CCL4/MIP-1 beta
ICAM-1	IL-16	CXCL2/MIP-2
IFN-gamma	IL-17	CCL5/RANTES
IL-1 alpha/IL-1F1	IL-23	CXCL12/SDF-1
IL-1 beta/IL-1F2	IL-27	CCL17/TARC
IL-1ra/IL-1F3	CXCL10/IP-10	TIMP-1
IL-2	CXCL11/I-TAC	TNF-alpha
IL-3	CXCL1/KC	TREM-1
IL-4

Assays for Analytes represented in the Mouse Cytokine Array Kit, Panel A

Analyte	Quantikine^® ELISA Kits	DuoSet^® ELISA Development Systems
CXCL13/BLC/BCA-1	MCX130	DY470
C5a		DY2150
G-CSF	MCS00	DY414
GM-CSF	MGM00	DY415
CCL1/I-309/TCA-3		DY845
CCL11/Eotaxin	MME00	DY420
ICAM-1	MIC100	DY796
IFN-gamma	MIF00	DY485
IL-1 alpha	MLA00	DY400
IL-1 beta	MLB00B	DY401
IL-1ra	MRA00	DY480
IL-2	M2000	DY402
IL-3	M3000	DY403
IL-4	M4000B	DY404
IL-5	M5000	DY405
IL-6	M6000B	DY406
IL-7	M7000	DY407
IL-10	M1000b	DY417
IL-12 p70	M1270	DY419
IL-13	M1300CB	DY413
IL-16
IL-17	M1700	DY421
IL-23	M2300	DY1887
IL-27	M2728
CXCL10/IP-10/CRG-2	MCX100	DY466
CXCL11/I-TAC		DY572
CXCL1/KC	MKC00B	DY453
M-CSF	MMC00	DY416
CCL2/MCP-1/JE	MJE00	DY479
CCL12/MCP-5	MCC120	DY428
CXCL9/MIG	MCX900	DY492
CCL3/MIP-1 alpha	MMA00	DY450
CCL4/MIP-1 beta	MMB00	DY451
CXCL2/MIP-2	MM200	DY452
CCL5/RANTES	MMR00	DY478
CXCL12/SDF-1	MCX120	DY460
CCL17/TARC		DY529
TIMP-1	MTM100	DY980
TNF-alpha	MTA00	DY410
TREM-1	MTRM10	DY1187

Data Examples

R&D Systems Mouse Cytokine Array, Panel A

View Larger Image

The Mouse Cytokine Array, Panel A utilizes capture antibodies spotted onto a nitrocellulose membrane to allow high-throughput multi-analyte profiling of 40 cytokines, chemokines, and more in a single sample. Mouse splenocytes treated with 100 ng/mL LPS for 20 hours were mixed with a cocktail of biotinylated detection antibodies, and then incubated with the Mouse Cytokine Array. The array was then incubated with streptavidin-horseradish peroxidase followed by chemiluminescent detection. After detection, the array data were quantitated to generate a protein profile (histogram). The table shows the analytes detected and their location on the membrane.

Preparation and Storage

Stability & Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Citations:

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

133 Citations: Showing 1 - 10
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Species	Applications	Sample Type
Mitogen-activated Protein Kinase Kinase Activity Maintains Acinar-to-Ductal Metaplasia and Is Required for Organ Regeneration in Pancreatitis Authors: CJ Halbrook, HJ Wen, JM Ruggeri, KK Takeuchi, Y Zhang, MP di Maglian, HC Crawford Cell Mol Gastroenterol Hepatol, 2017;3(1):99-118. 2017 Lack of ABCG2 Leads to Biventricular Dysfunction and Remodeling in Response to Hypoxia Authors: BM Nagy, C Nagaraj, B Egemnazaro, G Kwapiszews, RE Stauber, A Avian, H Olschewski, A Olschewski Front Physiol, 2017;8(0):98. 2017 DNA damage induced by Strontium-90 exposure at low concentrations in mesenchymal stromal cells: the functional consequences Authors: S Musilli, N Nicolas, Z El Ali, P Orellana-M, C Grand, K Tack, S Kerdine-R”, JM Bertho Sci Rep, 2017;7(0):41580. 2017 Fractalkine-CX3CR1 signaling is critical for progesterone-mediated neuroprotection in the retina Authors: SL Roche, AC Wyse-Jacks, AM Ruiz-Lopez, AM Byrne, TG Cotter Sci Rep, 2017;7(0):43067. 2017 Importance of CD200 expression by tumor or host cells to regulation of immunotherapy in a mouse breast cancer model Authors: A Curry, I Khatri, O Kos, F Zhu, R Gorczynski PLoS ONE, 2017;12(2):e0171586. 2017 Cardiac Function Remains Impaired Despite Reversible Cardiac Remodeling after Acute Experimental Viral Myocarditis Authors: PM Becher, F Gotzhein, K Klingel, F Escher, S Blankenber, D Westermann, D Lindner J Immunol Res, 2017;2017(0):6590609. 2017 Osteocyte secreted factors inhibit skeletal muscle differentiation Authors: CL Wood, PD Pajevic, JH Gooi Bone Rep, 2017;6(0):74-80. 2017 Exosomes function in antigen presentation during an in vivo Mycobacterium tuberculosis infection Authors: VL Smith, Y Cheng, BR Bryant, JS Schorey Sci Rep, 2017;7(0):43578. 2017 Complement drives glucosylceramide accumulation and tissue inflammation in Gaucher disease Authors: MK Pandey, TA Burrow, R Rani, LJ Martin, D Witte, KD Setchell, MA Mckay, AF Magnusen, W Zhang, B Liou, J Köhl, GA Grabowski Nature, 2017;543(7643):108-112. 2017 Serpin E2 promotes breast cancer metastasis by remodeling the tumor matrix and polarizing tumor associated macrophages Oncotarget, 2016;0(0):. 2016 PD-L1 blockade enhances response of pancreatic ductal adenocarcinoma to radiotherapy EMBO Mol Med, 2016;0(0):. 2016 Activation of IFN/STAT1 signalling predicts response to chemotherapy in oestrogen receptor-negative breast cancer Authors: ME Legrier, I BiŠche, J Gaston, A Beurdeley, V Yvonnet, O D‚as, A Thuleau, S Chƒteau-Jo, JL Servely, S Vacher, M Lassalle, S Depil, GC Tucker, JJ Fontaine, MF Poupon, S Roman-Roma, JG Judde, D Decaudin, S Cairo, E Marangoni Br. J. Cancer, 2016;114(2):177-87. 2016 Human and mouse monocytes display distinct signalling and cytokine profiles upon stimulation with FFAR2/FFAR3 short-chain fatty acid receptor agonists Sci Rep, 2016;6(0):34145. 2016 Targeting Serglycin Prevents Metastasis in Murine Mammary Carcinoma PLoS ONE, 2016;11(5):e0156151. 2016 Treatment of refractory cutaneous ulcers with mixed sheets consisting of peripheral blood mononuclear cells and fibroblasts Authors: Koji Ueno Sci Rep, 2016;6(0):28538. 2016 Repeated Activation of Lung Invariant NKT Cells Results in Chronic Obstructive Pulmonary Disease-Like Symptoms. Authors: Tsao C, Tsao P, Chen Y, Chuang Y PLoS ONE, 2016;11(1):e0147710. 2016 Proatherosclerotic Effect of the ?1-Subunit of Soluble Guanylyl Cyclase by Promoting Smooth Muscle Phenotypic Switching Authors: Maria Segura-Pui Am J Pathol, 2016;0(0):. 2016 The Thyroid Hormone Receptors Inhibit Hepatic Interleukin-6 Signaling During Endotoxemia Sci Rep, 2016;6(0):30990. 2016 Impact of the Sensory Neurons on Melanoma Growth In Vivo PLoS ONE, 2016;11(5):e0156095. 2016 Neutrophils suppress intraluminal NK-mediated tumor cell clearance and enhance extravasation of disseminated carcinoma cells Authors: A Spiegel, MW Brooks, S Houshyar, F Reinhardt, M Ardolino, E Fessler, MB Chen, JA Krall, J DeCock, IK Zervantona, A Iannello, Y Iwamoto, V Cortez-Ret, RD Kamm, MJ Pittet, DH Raulet, RA Weinberg Cancer Discov, 2016;0(0):. 2016 The Anti-Inflammatory Effects and Mechanisms of Eupafolin in Lipopolysaccharide-Induced Inflammatory Responses in RAW264.7 Macrophages PLoS ONE, 2016;11(7):e0158662. 2016 Immune response characterization and vaccine potential of a recombinant chimera comprising B-cell epitope of Aeromonas hydrophila outer membrane protein C and LTB Vaccine, 2016;34(50):6259-6266. 2016 Local immunosuppressive microenvironment enhances migration of melanoma cells to lungs in DJ-1 knockout mice. Authors: Chien C, Lee M, Liou H, Liou H, Fu W PLoS ONE, 2015;10(2):e0115827. 2015 IkappaBNS regulates murine Th17 differentiation during gut inflammation and infection. Authors: Annemann M, Wang Z, Plaza-Sirvent C, Glauben R, Schuster M, Ewald Sander F, Mamareli P, Kuhl A, Siegmund B, Lochner M, Schmitz I J Immunol, 2015;194(6):2888-98. 2015 Lenalidomide reduces microglial activation and behavioral deficits in a transgenic model of Parkinson's disease. Authors: Valera E, Mante M, Anderson S, Rockenstein E, Masliah E J Neuroinflammation, 2015;12(0):93. 2015 Extracellular Histones Induce Chemokine Production in Whole Blood Ex Vivo and Leukocyte Recruitment In Vivo. Authors: Westman J, Papareddy P, Dahlgren M, Chakrakodi B, Norrby-Teglund A, Smeds E, Linder A, Morgelin M, Johansson-Lindbom B, Egesten A, Herwald H PLoS Pathog, 2015;11(12):e1005319. 2015 Targeted Disruption of Ig-Hepta/Gpr116 Causes Emphysema-like Symptoms That Are Associated with Alveolar Macrophage Activation. Authors: Ariestanti D, Ando H, Hirose S, Nakamura N J Biol Chem, 2015;290(17):11032-40. 2015 Plasmacytoid Dendritic Cell Activation and IFN-alpha Production Are Prominent Features of Murine Autoimmune Pancreatitis and Human IgG4-Related Autoimmune Pancreatitis. Authors: Arai Y, Yamashita K, Kuriyama K, Shiokawa M, Kodama Y, Sakurai T, Mizugishi K, Uchida K, Kadowaki N, Takaori-Kondo A, Kudo M, Okazaki K, Strober W, Chiba T, Watanabe T J Immunol, 2015;195(7):3033-44. 2015 The circadian clock controls sunburn apoptosis and erythema in mouse skin. Authors: Gaddameedhi, Shobhan, Selby, Christop, Kemp, Michael, Ye, Rui, Sancar, Aziz J Invest Dermatol, 2015;135(4):1119-27. 2015 The generation of macrophages with anti-inflammatory activity in the absence of STAT6 signaling. Authors: Fleming B, Chandrasekaran P, Dillon L, Dalby E, Suresh R, Sarkar A, El-Sayed N, Mosser D J Leukoc Biol, 2015;98(3):395-407. 2015 Interleukin-35 Inhibits Endothelial Cell Activation by Suppressing MAPK-AP-1 Pathway. Authors: Sha X, Meng S, Li X, Xi H, Maddaloni M, Pascual D, Shan H, Jiang X, Wang H, Yang X J Biol Chem, 2015;290(31):19307-18. 2015 Left Ventricular Dysfunction and CXCR3 Ligands in Hypertension: From Animal Experiments to a Population-Based Pilot Study. Authors: Altara R, Gu Y, Struijker-Boudier H, Thijs L, Staessen J, Blankesteijn W PLoS ONE, 2015;10(10):e0141394. 2015 Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established disease. Authors: Grande M, Sanchez-Laorden B, Lopez-Blau C, De Frutos C, Boutet A, Arevalo M, Rowe R, Weiss S, Lopez-Novoa J, Nieto M Nat Med, 2015;21(9):989-97. 2015 Lysophosphatidic acid alters the expression profiles of angiogenic factors, cytokines, and chemokines in mouse liver sinusoidal endothelial cells. Authors: Chou C, Lai S, Ho C, Lin W, Chen C, Lee P, Peng F, Kuo S, Wu S, Lai H PLoS ONE, 2015;10(3):e0122060. 2015 Novel Role of TRPML2 in the Regulation of the Innate Immune Response. Authors: Sun L, Hua Y, Vergarajauregui S, Diab H, Puertollano R J Immunol, 2015;195(10):4922-32. 2015 Molecular Mechanisms Mediating Retinal Reactive Gliosis Following Bone Marrow Mesenchymal Stem Cell Transplantation. Authors: Tassoni A, Gutteridge A, Barber A, Osborne A, Martin K Stem Cells, 2015;33(10):3006-16. 2015 Tumor necrosis factor (TNF) receptor-associated factor (TRAF)-interacting protein (TRIP) negatively regulates the TRAF2 ubiquitin-dependent pathway by suppressing the TRAF2-sphingosine 1-phosphate (S1P) interaction. Authors: Park E, Choi S, Shin B, Yu J, Yu J, Hwang J, Yun H, Chung Y, Choi J, Choi Y, Rho J J Biol Chem, 2015;290(15):9660-73. 2015 Neuropathic pain is constitutively suppressed in early life by anti-inflammatory neuroimmune regulation. Authors: McKelvey R, Berta T, Old E, Ji R, Fitzgerald M J Neurosci, 2015;35(2):457-66. 2015 mRNA-transfected Dendritic Cells Expressing Polypeptides That Link MHC-I Presentation to Constitutive TLR4 Activation Confer Tumor Immunity. Authors: Cafri G, Sharbi-Yunger A, Tzehoval E, Alteber Z, Gross T, Vadai E, Margalit A, Gross G, Eisenbach L Mol Ther, 2015;23(8):1391-400. 2015 Specific medicinal plant polysaccharides effectively enhance the potency of a DC-based vaccine against mouse mammary tumor metastasis. Authors: Chang, Wei Ting, Lai, Tzung Hs, Chyan, Yau Jan, Yin, Shu Yi, Chen, Yung Hsi, Wei, Wen Chi, Yang, Ning-Sun PLoS ONE, 2015;10(3):e0122374. 2015 EpCAM Aptamer-siRNA Chimera Targets and Regress Epithelial Cancer. Authors: Subramanian N, Kanwar J, Kanwar R, Sreemanthula J, Biswas J, Khetan V, Krishnakumar S PLoS ONE, 2015;10(7):e0132407. 2015 Myeloid cell TRAF3 regulates immune responses and inhibits inflammation and tumor development in mice. Authors: Lalani A, Moore C, Luo C, Kreider B, Liu Y, Morse H, Xie P J Immunol, 2015;194(1):334-48. 2015 Supernatants of tumours treated with chemotherapy can alter tumour growth and development in vivo. Authors: Liu W, Scott K, Dalgleish A Anticancer Res, 2015;35(3):1499-508. 2015 Tumor-induced pressure in the bone microenvironment causes osteocytes to promote the growth of prostate cancer bone metastases. Authors: Sottnik J, Dai J, Zhang H, Campbell B, Keller E Cancer Res, 2015;75(11):2151-8. 2015 F-box protein FBXW7 inhibits cancer metastasis in a non-cell-autonomous manner. Authors: Yumimoto, Kanae, Akiyoshi, Sayuri, Ueo, Hiroki, Sagara, Yasuaki, Onoyama, Ichiro, Ueo, Hiroaki, Ohno, Shinji, Mori, Masaki, Mimori, Koshi, Nakayama, Keiichi J Clin Invest, 2015;125(2):621-35. 2015 Frostbite protection in mice expressing an antifreeze glycoprotein. Authors: Heisig, Martin, Mattessich, Sarah, Rembisz, Alison, Acar, Ali, Shapiro, Martin, Booth, Carmen J, Neelakanta, Girish, Fikrig, Erol PLoS ONE, 2015;10(2):e0116562. 2015 MicroRNA-26a/-26b-COX-2-MIP-2 Loop Regulates Allergic Inflammation and Allergic Inflammation-promoted Enhanced Tumorigenic and Metastatic Potential of Cancer Cells. Authors: Kwon Y, Kim Y, Eom S, Kim M, Park D, Kim H, Noh K, Lee H, Lee Y, Choe J, Kim Y, Jeoung D J Biol Chem, 2015;290(22):14245-66. 2015 Grapefruit-Derived Nanovectors Use an Activated Leukocyte Trafficking Pathway to Deliver Therapeutic Agents to Inflammatory Tumor Sites. Authors: Wang Q, Ren Y, Mu J, Egilmez N, Zhuang X, Deng Z, Zhang L, Yan J, Miller D, Zhang H Cancer Res, 2015;75(12):2520-9. 2015 Shikonin-enhanced cell immunogenicity of tumor vaccine is mediated by the differential effects of DAMP components. Authors: Lin T, Lin H, Chang W, Mitapalli S P, Hsiao P, Yin S, Yang N Mol Cancer, 2015;14(0):174. 2015 Combination of inflammation-related cytokines promotes long-term muscle stem cell expansion. Authors: Fu X, Xiao J, Wei Y, Li S, Liu Y, Yin J, Sun K, Sun H, Wang H, Zhang Z, Zhang B, Sheng C, Wang H, Hu P Cell Res, 2015;25(6):655-73. 2015 Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis. Authors: Bonapace L, Coissieux M, Wyckoff J, Mertz K, Varga Z, Junt T, Bentires-Alj M Nature, 2015;515(7525):130-3. 2015 Role of Rip2 in development of tumor-infiltrating MDSCs and bladder cancer metastasis. Authors: Zhang, Hanwei, Chin, Arnold I PLoS ONE, 2014;9(4):e94793. 2014 IL-1alpha and complement cooperate in triggering local neutrophilic inflammation in response to adenovirus and eliminating virus-containing cells. Authors: Di Paolo N, Baldwin L, Irons E, Papayannopoulou T, Tomlinson S, Shayakhmetov D PLoS Pathog, 2014;10(3):e1004035. 2014 Human herpesvirus 6A infection in CD46 transgenic mice: viral persistence in the brain and increased production of proinflammatory chemokines via Toll-like receptor 9. Authors: Reynaud J, Jegou J, Welsch J, Horvat B J Virol, 2014;88(10):5421-36. 2014 Infection with Leishmania major induces a cellular stress response in macrophages. Authors: Filardy A, Costa-da-Silva A, Koeller C, Guimaraes-Pinto K, Ribeiro-Gomes F, Lopes M, Heise N, Freire-de-Lima C, Nunes M, DosReis G PLoS ONE, 2014;9(1):e85715. 2014 Sc65 is a novel endoplasmic reticulum protein that regulates bone mass homeostasis. Authors: Gruenwald K, Castagnola P, Besio R, Dimori M, Chen Y, Akel N, Swain F, Skinner R, Eyre D, Gaddy D, Suva L, Morello R J Bone Miner Res, 2014;29(3):666-75. 2014 A paracrine network regulates the cross-talk between human lung stem cells and the stroma. Authors: Ruiz E, Oeztuerk-Winder F, Ventura J Nat Commun, 2014;5(0):3175. 2014 Notch-dependent repression of miR-155 in the bone marrow niche regulates hematopoiesis in an NF-kappaB-dependent manner. Authors: Wang L, Zhang H, Rodriguez S, Cao L, Parish J, Mumaw C, Zollman A, Kamoka M, Mu J, Chen D, Srour E, Chitteti B, HogenEsch H, Tu X, Bellido T, Boswell H, Manshouri T, Verstovsek S, Yoder M, Kapur R, Cardoso A, Carlesso N Cell Stem Cell, 2014;15(1):51-65. 2014 Metabolic reprogramming of macrophages: glucose transporter 1 (GLUT1)-mediated glucose metabolism drives a proinflammatory phenotype. Authors: Freemerman A, Johnson A, Sacks G, Milner J, Kirk E, Troester M, Macintyre A, Goraksha-Hicks P, Rathmell J, Makowski L J Biol Chem, 2014;289(11):7884-96. 2014 The Src family kinases Hck, Fgr, and Lyn are critical for the generation of the in vivo inflammatory environment without a direct role in leukocyte recruitment. Authors: Kovacs M, Nemeth T, Jakus Z, Sitaru C, Simon E, Futosi K, Botz B, Helyes Z, Lowell C, Mocsai A J Exp Med, 2014;211(10):1993-2011. 2014 Effects of insulin resistance on skeletal muscle growth and exercise capacity in type 2 diabetic mouse models. Authors: Ostler, Joseph E, Maurya, Santosh, Dials, Justin, Roof, Steve R, Devor, Steven T, Ziolo, Mark T, Periasamy, Muthu Am J Physiol Endocrinol Metab, 2014;306(6):E592-605. 2014 Cancer affects microRNA expression, release, and function in cardiac and skeletal muscle. Authors: Chen D, Goswami C, Burnett R, Anjanappa M, Bhat-Nakshatri P, Muller W, Nakshatri H Cancer Res, 2014;74(16):4270-81. 2014 Macrophage-inducing FasL on chondrocytes forms immune privilege in cartilage tissue engineering, enhancing in vivo regeneration. Authors: Fujihara Y, Takato T, Hoshi K Stem Cells, 2014;32(5):1208-19. 2014 Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) prevents lipopolysaccharide (LPS)-induced, sepsis-related severe acute lung injury in mice. Authors: Takaoka, Yuki, Goto, Shigeru, Nakano, Toshiaki, Tseng, Hui-Peng, Yang, Shih-Min, Kawamoto, Seiji, Ono, Kazuhisa, Chen, Chao-Lon Sci Rep, 2014;4(0):5204. 2014 Bone marrow stromal cell-derived exosomes as communicators in drug resistance in multiple myeloma cells. Authors: Wang J, Hendrix A, Hernot S, Lemaire M, De Bruyne E, Van Valckenborgh E, Lahoutte T, De Wever O, Vanderkerken K, Menu E Blood, 2014;124(4):555-66. 2014 Absence of fibromodulin affects matrix composition, collagen deposition and cell turnover in healthy and fibrotic lung parenchyma. Authors: Rydell-Tormanen K, Andreasson K, Hesselstrand R, Westergren-Thorsson G Sci Rep, 2014;4(0):6383. 2014 HPV16-associated tumors control myeloid cell homeostasis in lymphoid organs, generating a suppressor environment for T cells. Authors: Stone S, Rossetti R, Bolpetti A, Boccardo E, Souza P, Lepique A J Leukoc Biol, 2014;96(4):619-31. 2014 Periostin controls keratinocyte proliferation and differentiation by interacting with the paracrine IL-1alpha/IL-6 loop. Authors: Taniguchi K, Arima K, Masuoka M, Ohta S, Shiraishi H, Ontsuka K, Suzuki S, Inamitsu M, Yamamoto K, Simmons O, Toda S, Conway S, Hamasaki Y, Izuhara K J Invest Dermatol, 2014;134(5):1295-304. 2014 BMP pathway regulation of and by macrophages. Authors: Talati M, West J, Zaynagetdinov R, Hong C, Han W, Blackwell T, Robinson L, Blackwell T, Lane K PLoS ONE, 2014;9(4):e94119. 2014 The pathogenic mechanism of the Mycobacterium ulcerans virulence factor, mycolactone, depends on blockade of protein translocation into the ER. Authors: Hall, Belinda, Hill, Kirsti, McKenna, Michael, Ogbechi, Joy, High, Stephen, Willis, Anne E, Simmonds, Rachel E PLoS Pathog, 2014;10(4):e1004061. 2014 Dystrophic mdx mice develop severe cardiac and respiratory dysfunction following genetic ablation of the anti-inflammatory cytokine IL-10. Authors: Nitahara-Kasahara Y, Hayashita-Kinoh H, Chiyo T, Nishiyama A, Okada H, Takeda S, Okada T Hum Mol Genet, 2014;23(15):3990-4000. 2014 Novel mechanisms underlying the immediate and transient global tolerization of splenic dendritic cells after vaccination with a self-antigen. Authors: Farkas A, Finn O J Immunol, 2014;192(2):658-65. 2014 IL-15 deficient tax mice reveal a role for IL-1alpha in tumor immunity. Authors: Rauch D, Harding J, Ratner L PLoS ONE, 2014;9(1):e85028. 2014 Improving membrane based multiplex immunoassays for semi-quantitative detection of multiple cytokines in a single sample. Authors: Altara, Raffaele, Manca, Marco, Hessel, Marleen, Janssen, Ben J, Struijker-Boudier, Harry H, Hermans, Rob J J, Blankesteijn, W Matthi BMC Biotechnol, 2014;14(0):63. 2014 Effect of low frequency magnetic fields on melanoma: tumor inhibition and immune modulation. Authors: Nie Y, DU L, Mou Y, Xu Z, Weng L, Du Y, Zhu Y, Hou Y, Wang T BMC Cancer, 2013;13(0):582. 2013 Regulation of adult hematopoiesis by the a disintegrin and metalloproteinase 10 (ADAM10). Authors: Weber S, Wetzel S, Prox J, Lehmann T, Schneppenheim J, Donners M, Saftig P Biochem Biophys Res Commun, 2013;442(3):234-41. 2013 The bradykinin B1 receptor regulates Abeta deposition and neuroinflammation in Tg-SwDI mice. Authors: Passos G, Medeiros R, Cheng D, Vasilevko V, Laferla F, Cribbs D Am J Pathol, 2013;182(5):1740-9. 2013 Anticancer compound ABT-263 accelerates apoptosis in virus-infected cells and imbalances cytokine production and lowers survival rates of infected mice. Authors: Kakkola L, Denisova O, Tynell J, Viiliainen J, Ysenbaert T, Matos R, Nagaraj A, Ohman T, Kuivanen S, Paavilainen H, Feng L, Yadav B, Julkunen I, Vapalahti O, Hukkanen V, Stenman J, Aittokallio T, Verschuren E, Ojala P, Nyman T, Saelens X, Dzeyk K, Kainov D Cell Death Dis, 2013;4(0):e742. 2013 Blockade of NOX2 and STIM1 signaling limits lipopolysaccharide-induced vascular inflammation. Authors: Gandhirajan, Rajesh K, Meng, Shu, Chandramoorthy, Harish C, Mallilankaraman, Karthik, Mancarella, Salvator, Gao, Hui, Razmpour, Roshanak, Yang, Xiao-Fen, Houser, Steven R, Chen, Ju, Koch, Walter J, Wang, Hong, Soboloff, Jonathan, Gill, Donald L, Madesh, Muniswam J Clin Invest, 2013;123(2):887-902. 2013 Concomitant interferon alpha stimulation and TLR3 activation induces neuronal expression of depression-related genes that are elevated in the brain of suicidal persons. Authors: Hoyo-Becerra, Carolina, Huebener, Anastasi, Trippler, Martin, Lutterbeck, Melanie, Liu, Zijian J, Truebner, Kurt, Bajanowski, Thomas, Gerken, Guido, Hermann, Dirk M, Schlaak, Joerg F PLoS ONE, 2013;8(12):e83149. 2013 A combinatorial F box protein directed pathway controls TRAF adaptor stability to regulate inflammation. Authors: Chen B, Coon T, Glasser J, McVerry B, Zhao J, Zhao Y, Zou C, Ellis B, Sciurba F, Zhang Y, Mallampalli R Nat Immunol, 2013;14(5):470-9. 2013 Exosomes isolated from mycobacteria-infected mice or cultured macrophages can recruit and activate immune cells in vitro and in vivo. Authors: Singh PP, Smith VL, Karakousis PC, Schorey JS J. Immunol., 2012;189(2):777-85. 2012 Histone Deacetylase 3 Mediates Allergic Skin Inflammation by Regulating Expression of MCP1 Protein. Authors: Kim Y, Kim K, Park D, Lee E, Lee H, Lee YS, Choe J, Jeoung D J. Biol. Chem., 2012;287(31):25844-59. 2012 Dietary blue pigments derived from genipin, attenuate inflammation by inhibiting LPS-induced iNOS and COX-2 expression via the NF-kappaB inactivation. Authors: Wang QS, Xiang Y, Cui YL, Lin KM, Zhang XF PLoS ONE, 2012;7(3):e34122. 2012 Abcg2 deficiency augments oxidative stress and cognitive deficits in Tg-SwDI transgenic mice. J. Neurochem., 2012;233(0):456-469. 2012 Clusterin induces the secretion of TNF-ÃŽÂ± and the chemotactic migration of macrophages. Authors: Shim YJ, Kang BH, Choi BK, Park IS, Min BH Biochem. Biophys. Res. Commun., 2012;422(1):200-5. 2012 Murine bone marrow-derived macrophages differentiated with GM-CSF become foam cells by PI3Kgamma-dependent fluid-phase pinocytosis of native LDL. Authors: Anzinger JJ, Chang J, Xu Q, Barthwal MK, Bohnacker T, Wymann MP, Kruth HS J. Lipid Res., 2012;53(1):34-42. 2012 Liver-specific expression of transcriptionally active SREBP-1c is associated with fatty liver and increased visceral fat mass. 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Immunol., 2012;188(12):5935-43. 2012 The MSHA Strain of Pseudomonas Aeruginosa Activated TLR Pathway and Enhanced HIV-1 DNA Vaccine Immunoreactivity. Authors: Hou J, Liu Y, Liu Y, Shao Y PLoS ONE, 2012;7(10):e47724. 2012 Interleukin-33 primes mast cells for activation by IgG immune complexes. Authors: Kaieda S, Wang J, Shnayder R, Fishgal N, Hei H, Lee R, Stevens R, Nigrovic P PLoS ONE, 2012;7(10):e47252. 2012 TGFbeta signalling plays an important role in IL4-induced alternative activation of microglia. J Neuroinflammation, 2012;9(0):210. 2012 A novel small molecule, HK-156, inhibits lipopolysaccharide-induced activation of NF-kappaB signaling and improves survival in mouse models of sepsis. Acta Pharmacol. Sin., 2012;33(9):1204-16. 2012 The role of alveolar epithelial cells in initiating and shaping pulmonary immune responses: communication between innate and adaptive immune systems. 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Authors: Denoyer A, Godefroy D, Celerier I, Frugier J, Riancho L, Baudouin F, Rostene W, Baudouin C Mucosal Immunol, 2012;5(0):702. 2012 The synthetic triterpenoid CDDO-methyl ester delays estrogen receptor-negative mammary carcinogenesis in polyoma middle T mice. Authors: Tran K, Risingsong R, Royce D Cancer Prev Res (Phila), 2012;5(5):726-34. 2012 Early-outgrowth bone marrow cells attenuate renal injury and dysfunction via an antioxidant effect in a mouse model of type 2 diabetes. Diabetes, 2012;61(8):2114-25. 2012 Fine-tuning nucleophosmin in macrophage differentiation and activation. Authors: Guery L, Benikhlef N, Gautier T, Paul C, Jego G, Dufour E, Jacquel A, Cally R, Manoury B, Vanden Berghe T, Vandenabeele P, Droin N, Solary E Blood, 2011;118(17):4694-704. 2011 Intratracheal transplantation of human umbilical cord blood-derived mesenchymal stem cells attenuates Escherichia coli-induced acute lung injury in mice. 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Authors: Chattopadhyay A, Robinson N, Sandhu JK, Finlay BB, Sad S, Krishnan L Infect. Immun., 2010;78(5):2292-301. 2010 JNK-induced MCP-1 production in spinal cord astrocytes contributes to central sensitization and neuropathic pain. Authors: Gao YJ, Zhang L, Samad OA, Suter MR, Yasuhiko K, Xu ZZ, Park JY, Lind AL, Ma Q, Ji RR J. Neurosci., 2009;29(13):4096-108. 2009 Inhibition of the chemokine (C-C motif) ligand 2/chemokine (C-C motif) receptor 2 pathway attenuates hyperglycaemia and inflammation in a mouse model of hepatic steatosis and lipoatrophy. Authors: Yang SJ, IglayReger HB, Kadouh HC, Bodary PF Diabetologia, 2009;52(0):972-81. 2009 Paracrine induction of endothelium by tumor exosomes. Authors: Hood JL, Pan H, Lanza GM, Wickline SA, Lab. Invest., 2009;89(11):1317-28. 2009 Alum induces innate immune responses through macrophage and mast cell sensors, but these sensors are not required for alum to act as an adjuvant for specific immunity. Authors: McKee AS, Munks MW, MacLeod MK, Fleenor CJ, Van Rooijen N, Kappler JW, Marrack P J. Immunol., 2009;183(7):4403-14. 2009 Virus binding to a plasma membrane receptor triggers interleukin-1 alpha-mediated proinflammatory macrophage response in vivo. Authors: Di Paolo NC, Miao EA, Iwakura Y, Murali-Krishna K, Aderem A, Flavell RA, Papayannopoulou T, Shayakhmetov DM Immunity, 2009;31(1):110-21. 2009 Expand to show all 133 Citations

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