Proteome Profiler Mouse Cytokine Array Kit, Panel A (ARY006): R&D Systems
Kit Summary

A membrane-based antibody array for the parallel determination of the relative levels of selected mouse cytokines and chemokines. Validated for analyte detection in cell culture supernates, cell lysates, tissue lysates, serum, and plasma.

Key Benefits

  • Detects 40 mouse cytokines, chemokines, and acute phase proteins simultaneously
  • Requires no specialized equipment
  • Compatible with LI-COR and chemiluminescence detection
 

Principle of the Assay

The Proteome Profiler Mouse Cytokine Array Kit, Panel A is a membrane-based sandwich immunoassay. Samples are mixed with a cocktail of biotinylated detection antibodies (Step 1) and then incubated with the array membrane which is spotted in duplicate with capture antibodies to specific target proteins (Step 2). Captured proteins are visualized using chemiluminescent detection reagents (Step 3). The signal produced is proportional to the amount of analyte bound.

Why Use an Antibody Array to Detect Multiple Cytokines?

Determining the expression of multiple cytokines in a single sample can be expensive, time consuming and can require specialized equipment. Performing multiple immunoprecipitations and Western blots requires time, labor, and reagents. The use of a multiplex antibody array to detect multiple cytokines in a single sample can be cost-effective and also save time and sample.

 

 

Kit Contents
  • Rectangular 4-Well Multi-dish
  • 4 Mouse Cytokine Array, Panel A nitrocellulose membranes spotted with 40 different antibodies to mouse cytokines, chemokines, and acute phase proteins
  • Array Buffer 4
  • Array Buffer 6
  • Chemi Reagent 1
  • Chemi Reagent 2
  • Detection Antibody Cocktail, Mouse Cytokine Array, Panel A
  • Streptavidin-HRP
  • Transparency Overlay Template
  • Wash Buffer Concentrate (25X)

For a complete list of the kit contents and necessary materials, please see the Materials Provided/Other Supplies Required sections of the product datasheet.

Stability and Storage

Store the unopened kit at 2 °C to 8 °C. Do not use past kit expiration date.  

 
Simultaneously detect the levels of these cytokines, chemokines, and acute phase proteins in a single sample.
CXCL13/BLC/BCA-1 IL-5 M-CSF
C5a IL-6 CCL2/JE/MCP-1
G-CSF IL-7 CCL12/MCP-5
GM-CSF IL-10 CXCL9/MIG
CCL1/I-309 IL-12 p70 CCL3/MIP-1 alpha
CCL11/Eotaxin IL-13 CCL4/MIP-1 beta
ICAM-1 IL-16 CXCL2/MIP-2
IFN-gamma IL-17 CCL5/RANTES
IL-1 alpha/IL-1F1 IL-23 CXCL12/SDF-1
IL-1 beta/IL-1F2 IL-27 CCL17/TARC
IL-1ra/IL-1F3 CXCL10/IP-10 TIMP-1
IL-2 CXCL11/I-TAC TNF-alpha
IL-3 CXCL1/KC TREM-1
IL-4    

 

Assays for Analytes represented in the Mouse Cytokine Array Kit, Panel A

Analyte Quantikine® ELISA Kits DuoSet® ELISA Development Systems
CXCL13/BLC/BCA-1 MCX130 DY470
C5a   DY2150
G-CSF MCS00 DY414
GM-CSF MGM00 DY415
CCL1/I-309/TCA-3   DY845
CCL11/Eotaxin MME00 DY420
ICAM-1 MIC100 DY796
IFN-gamma MIF00 DY485
IL-1 alpha MLA00 DY400
IL-1 beta MLB00B DY401
IL-1ra MRA00 DY480
IL-2 M2000 DY402
IL-3 M3000 DY403
IL-4 M4000B DY404
IL-5 M5000 DY405
IL-6 M6000B DY406
IL-7 M7000 DY407
IL-10 M1000b DY417
IL-12 p70 M1270 DY419
IL-13 M1300CB DY413
IL-16    
IL-17 M1700 DY421
IL-23 M2300 DY1887
IL-27 M2728  
CXCL10/IP-10/CRG-2 MCX100 DY466
CXCL11/I-TAC   DY572
CXCL1/KC MKC00B DY453
M-CSF MMC00 DY416
CCL2/MCP-1/JE MJE00 DY479
CCL12/MCP-5 MCC120 DY428
CXCL9/MIG MCX900 DY492
CCL3/MIP-1 alpha MMA00 DY450
CCL4/MIP-1 beta MMB00 DY451
CXCL2/MIP-2 MM200 DY452
CCL5/RANTES MMR00 DY478
CXCL12/SDF-1 MCX120 DY460
CCL17/TARC   DY529
TIMP-1 MTM100 DY980
TNF-alpha MTA00 DY410
TREM-1 MTRM10 DY1187

 

 
Data Examples
R&D Systems Mouse Cytokine Array, Panel A
View Larger Image

The Mouse Cytokine Array, Panel A utilizes capture antibodies spotted onto a nitrocellulose membrane to allow high-throughput multi-analyte profiling of 40 cytokines, chemokines, and more in a single sample. Mouse splenocytes treated with 100 ng/mL LPS for 20 hours were mixed with a cocktail of biotinylated detection antibodies, and then incubated with the Mouse Cytokine Array. The array was then incubated with streptavidin-horseradish peroxidase followed by chemiluminescent detection. After detection, the array data were quantitated to generate a protein profile (histogram). The table shows the analytes detected and their location on the membrane.

Preparation and Storage
  • Stability & Storage
    Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Citations:

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

138 Citations: Showing 1 - 10
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Sample Type
  1. Lack of ABCG2 Leads to Biventricular Dysfunction and Remodeling in Response to Hypoxia
    Authors: BM Nagy, C Nagaraj, B Egemnazaro, G Kwapiszews, RE Stauber, A Avian, H Olschewski, A Olschewski
    Front Physiol, 2017;8(0):98. 2017
  2. Complement drives glucosylceramide accumulation and tissue inflammation in Gaucher disease
    Authors: MK Pandey, TA Burrow, R Rani, LJ Martin, D Witte, KD Setchell, MA Mckay, AF Magnusen, W Zhang, B Liou, J Köhl, GA Grabowski
    Nature, 2017;543(7643):108-112. 2017
  3. Fractalkine-CX3CR1 signaling is critical for progesterone-mediated neuroprotection in the retina
    Authors: SL Roche, AC Wyse-Jacks, AM Ruiz-Lopez, AM Byrne, TG Cotter
    Sci Rep, 2017;7(0):43067. 2017
  4. Importance of CD200 expression by tumor or host cells to regulation of immunotherapy in a mouse breast cancer model
    Authors: A Curry, I Khatri, O Kos, F Zhu, R Gorczynski
    PLoS ONE, 2017;12(2):e0171586. 2017
  5. Mitogen-activated Protein Kinase Kinase Activity Maintains Acinar-to-Ductal Metaplasia and Is Required for Organ Regeneration in Pancreatitis
    Authors: CJ Halbrook, HJ Wen, JM Ruggeri, KK Takeuchi, Y Zhang, MP di Maglian, HC Crawford
    Cell Mol Gastroenterol Hepatol, 2017;3(1):99-118. 2017
  6. DNA damage induced by Strontium-90 exposure at low concentrations in mesenchymal stromal cells: the functional consequences
    Authors: S Musilli, N Nicolas, Z El Ali, P Orellana-M, C Grand, K Tack, S Kerdine-R”, JM Bertho
    Sci Rep, 2017;7(0):41580. 2017
  7. Cardiac Function Remains Impaired Despite Reversible Cardiac Remodeling after Acute Experimental Viral Myocarditis
    Authors: PM Becher, F Gotzhein, K Klingel, F Escher, S Blankenber, D Westermann, D Lindner
    J Immunol Res, 2017;2017(0):6590609. 2017
  8. Exosomes function in antigen presentation during an in vivo Mycobacterium tuberculosis infection
    Authors: VL Smith, Y Cheng, BR Bryant, JS Schorey
    Sci Rep, 2017;7(0):43578. 2017
  9. HDAC3 inhibition ameliorates spinal cord injury by immunomodulation
    Authors: T Kuboyama, S Wahane, Y Huang, X Zhou, JK Wong, A Koemeter-C, M Martini, RH Friedel, H Zou
    Sci Rep, 2017;7(1):8641. 2017
  10. Recruited Monocytes and Type 2 Immunity Promote Lung Regeneration following Pneumonectomy
    Authors: AJ Lechner, IH Driver, J Lee, CM Conroy, A Nagle, RM Locksley, JR Rock
    Cell Stem Cell, 2017;0(0):. 2017
  11. Calf Spleen Extractive Injection protects mice against cyclophosphamide-induced hematopoietic injury through G-CSF-mediated JAK2/STAT3 signaling
    Authors: W Lu, D Jia, S An, M Mu, X Qiao, Y Liu, X Li, D Wang
    Sci Rep, 2017;7(1):8402. 2017
  12. Galectin-3: A Positive Regulator of Leukocyte Recruitment in the Inflamed Microcirculation
    Authors: BR Gittens, JV Bodkin, S Nourshargh, M Perretti, D Cooper
    J. Immunol., 2017;0(0):. 2017
  13. Osteocyte secreted factors inhibit skeletal muscle differentiation
    Authors: CL Wood, PD Pajevic, JH Gooi
    Bone Rep, 2017;6(0):74-80. 2017
  14. Neuronal p38? mediates synaptic and cognitive dysfunction in an Alzheimer's mouse model by controlling ?-amyloid production
    Authors: S Colié, S Sarroca, R Palenzuela, I Garcia, A Matheu, R Corpas, CG Dotti, JA Esteban, C Sanfeliu, AR Nebreda
    Sci Rep, 2017;7(0):45306. 2017
  15. The Thyroid Hormone Receptors Inhibit Hepatic Interleukin-6 Signaling During Endotoxemia
    Sci Rep, 2016;6(0):30990. 2016
  16. Immune response characterization and vaccine potential of a recombinant chimera comprising B-cell epitope of Aeromonas hydrophila outer membrane protein C and LTB
    Vaccine, 2016;34(50):6259-6266. 2016
  17. Human and mouse monocytes display distinct signalling and cytokine profiles upon stimulation with FFAR2/FFAR3 short-chain fatty acid receptor agonists
    Sci Rep, 2016;6(0):34145. 2016
  18. Proatherosclerotic Effect of the ?1-Subunit of Soluble Guanylyl Cyclase by Promoting Smooth Muscle Phenotypic Switching
    Authors: Maria Segura-Pui
    Am J Pathol, 2016;0(0):. 2016
  19. Targeting Serglycin Prevents Metastasis in Murine Mammary Carcinoma
    PLoS ONE, 2016;11(5):e0156151. 2016
  20. Treatment of refractory cutaneous ulcers with mixed sheets consisting of peripheral blood mononuclear cells and fibroblasts
    Authors: Koji Ueno
    Sci Rep, 2016;6(0):28538. 2016
  21. Impact of the Sensory Neurons on Melanoma Growth In Vivo
    PLoS ONE, 2016;11(5):e0156095. 2016
  22. The Anti-Inflammatory Effects and Mechanisms of Eupafolin in Lipopolysaccharide-Induced Inflammatory Responses in RAW264.7 Macrophages
    PLoS ONE, 2016;11(7):e0158662. 2016
  23. Activation of IFN/STAT1 signalling predicts response to chemotherapy in oestrogen receptor-negative breast cancer
    Authors: ME Legrier, I BiŠche, J Gaston, A Beurdeley, V Yvonnet, O D‚as, A Thuleau, S Chƒteau-Jo, JL Servely, S Vacher, M Lassalle, S Depil, GC Tucker, JJ Fontaine, MF Poupon, S Roman-Roma, JG Judde, D Decaudin, S Cairo, E Marangoni
    Br. J. Cancer, 2016;114(2):177-87. 2016
  24. PD-L1 blockade enhances response of pancreatic ductal adenocarcinoma to radiotherapy
    EMBO Mol Med, 2016;0(0):. 2016
  25. Neutrophils suppress intraluminal NK-mediated tumor cell clearance and enhance extravasation of disseminated carcinoma cells
    Authors: A Spiegel, MW Brooks, S Houshyar, F Reinhardt, M Ardolino, E Fessler, MB Chen, JA Krall, J DeCock, IK Zervantona, A Iannello, Y Iwamoto, V Cortez-Ret, RD Kamm, MJ Pittet, DH Raulet, RA Weinberg
    Cancer Discov, 2016;0(0):. 2016
  26. Serpin E2 promotes breast cancer metastasis by remodeling the tumor matrix and polarizing tumor associated macrophages
    Oncotarget, 2016;0(0):. 2016
  27. Repeated Activation of Lung Invariant NKT Cells Results in Chronic Obstructive Pulmonary Disease-Like Symptoms.
    Authors: Tsao C, Tsao P, Chen Y, Chuang Y
    PLoS ONE, 2016;11(1):e0147710. 2016
  28. Left Ventricular Dysfunction and CXCR3 Ligands in Hypertension: From Animal Experiments to a Population-Based Pilot Study.
    Authors: Altara R, Gu Y, Struijker-Boudier H, Thijs L, Staessen J, Blankesteijn W
    PLoS ONE, 2015;10(10):e0141394. 2015
  29. Extracellular Histones Induce Chemokine Production in Whole Blood Ex Vivo and Leukocyte Recruitment In Vivo.
    Authors: Westman J, Papareddy P, Dahlgren M, Chakrakodi B, Norrby-Teglund A, Smeds E, Linder A, Morgelin M, Johansson-Lindbom B, Egesten A, Herwald H
    PLoS Pathog, 2015;11(12):e1005319. 2015
  30. Lenalidomide reduces microglial activation and behavioral deficits in a transgenic model of Parkinson's disease.
    Authors: Valera E, Mante M, Anderson S, Rockenstein E, Masliah E
    J Neuroinflammation, 2015;12(0):93. 2015
  31. Molecular Mechanisms Mediating Retinal Reactive Gliosis Following Bone Marrow Mesenchymal Stem Cell Transplantation.
    Authors: Tassoni A, Gutteridge A, Barber A, Osborne A, Martin K
    Stem Cells, 2015;33(10):3006-16. 2015
  32. Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis.
    Authors: Bonapace L, Coissieux M, Wyckoff J, Mertz K, Varga Z, Junt T, Bentires-Alj M
    Nature, 2015;515(7525):130-3. 2015
  33. Interleukin-35 Inhibits Endothelial Cell Activation by Suppressing MAPK-AP-1 Pathway.
    Authors: Sha X, Meng S, Li X, Xi H, Maddaloni M, Pascual D, Shan H, Jiang X, Wang H, Yang X
    J Biol Chem, 2015;290(31):19307-18. 2015
  34. Frostbite protection in mice expressing an antifreeze glycoprotein.
    Authors: Heisig, Martin, Mattessich, Sarah, Rembisz, Alison, Acar, Ali, Shapiro, Martin, Booth, Carmen J, Neelakanta, Girish, Fikrig, Erol
    PLoS ONE, 2015;10(2):e0116562. 2015
  35. Tumor necrosis factor (TNF) receptor-associated factor (TRAF)-interacting protein (TRIP) negatively regulates the TRAF2 ubiquitin-dependent pathway by suppressing the TRAF2-sphingosine 1-phosphate (S1P) interaction.
    Authors: Park E, Choi S, Shin B, Yu J, Yu J, Hwang J, Yun H, Chung Y, Choi J, Choi Y, Rho J
    J Biol Chem, 2015;290(15):9660-73. 2015
  36. Myeloid cell TRAF3 regulates immune responses and inhibits inflammation and tumor development in mice.
    Authors: Lalani A, Moore C, Luo C, Kreider B, Liu Y, Morse H, Xie P
    J Immunol, 2015;194(1):334-48. 2015
  37. Tumor-induced pressure in the bone microenvironment causes osteocytes to promote the growth of prostate cancer bone metastases.
    Authors: Sottnik J, Dai J, Zhang H, Campbell B, Keller E
    Cancer Res, 2015;75(11):2151-8. 2015
  38. Shikonin-enhanced cell immunogenicity of tumor vaccine is mediated by the differential effects of DAMP components.
    Authors: Lin T, Lin H, Chang W, Mitapalli S P, Hsiao P, Yin S, Yang N
    Mol Cancer, 2015;14(0):174. 2015
  39. EpCAM Aptamer-siRNA Chimera Targets and Regress Epithelial Cancer.
    Authors: Subramanian N, Kanwar J, Kanwar R, Sreemanthula J, Biswas J, Khetan V, Krishnakumar S
    PLoS ONE, 2015;10(7):e0132407. 2015
  40. Plasmacytoid Dendritic Cell Activation and IFN-alpha Production Are Prominent Features of Murine Autoimmune Pancreatitis and Human IgG4-Related Autoimmune Pancreatitis.
    Authors: Arai Y, Yamashita K, Kuriyama K, Shiokawa M, Kodama Y, Sakurai T, Mizugishi K, Uchida K, Kadowaki N, Takaori-Kondo A, Kudo M, Okazaki K, Strober W, Chiba T, Watanabe T
    J Immunol, 2015;195(7):3033-44. 2015
  41. mRNA-transfected Dendritic Cells Expressing Polypeptides That Link MHC-I Presentation to Constitutive TLR4 Activation Confer Tumor Immunity.
    Authors: Cafri G, Sharbi-Yunger A, Tzehoval E, Alteber Z, Gross T, Vadai E, Margalit A, Gross G, Eisenbach L
    Mol Ther, 2015;23(8):1391-400. 2015
  42. F-box protein FBXW7 inhibits cancer metastasis in a non-cell-autonomous manner.
    Authors: Yumimoto, Kanae, Akiyoshi, Sayuri, Ueo, Hiroki, Sagara, Yasuaki, Onoyama, Ichiro, Ueo, Hiroaki, Ohno, Shinji, Mori, Masaki, Mimori, Koshi, Nakayama, Keiichi
    J Clin Invest, 2015;125(2):621-35. 2015
  43. Combination of inflammation-related cytokines promotes long-term muscle stem cell expansion.
    Authors: Fu X, Xiao J, Wei Y, Li S, Liu Y, Yin J, Sun K, Sun H, Wang H, Zhang Z, Zhang B, Sheng C, Wang H, Hu P
    Cell Res, 2015;25(6):655-73. 2015
  44. Neuropathic pain is constitutively suppressed in early life by anti-inflammatory neuroimmune regulation.
    Authors: McKelvey R, Berta T, Old E, Ji R, Fitzgerald M
    J Neurosci, 2015;35(2):457-66. 2015
  45. Specific medicinal plant polysaccharides effectively enhance the potency of a DC-based vaccine against mouse mammary tumor metastasis.
    Authors: Chang, Wei Ting, Lai, Tzung Hs, Chyan, Yau Jan, Yin, Shu Yi, Chen, Yung Hsi, Wei, Wen Chi, Yang, Ning-Sun
    PLoS ONE, 2015;10(3):e0122374. 2015
  46. Local immunosuppressive microenvironment enhances migration of melanoma cells to lungs in DJ-1 knockout mice.
    Authors: Chien C, Lee M, Liou H, Liou H, Fu W
    PLoS ONE, 2015;10(2):e0115827. 2015
  47. Grapefruit-Derived Nanovectors Use an Activated Leukocyte Trafficking Pathway to Deliver Therapeutic Agents to Inflammatory Tumor Sites.
    Authors: Wang Q, Ren Y, Mu J, Egilmez N, Zhuang X, Deng Z, Zhang L, Yan J, Miller D, Zhang H
    Cancer Res, 2015;75(12):2520-9. 2015
  48. MicroRNA-26a/-26b-COX-2-MIP-2 Loop Regulates Allergic Inflammation and Allergic Inflammation-promoted Enhanced Tumorigenic and Metastatic Potential of Cancer Cells.
    Authors: Kwon Y, Kim Y, Eom S, Kim M, Park D, Kim H, Noh K, Lee H, Lee Y, Choe J, Kim Y, Jeoung D
    J Biol Chem, 2015;290(22):14245-66. 2015
  49. Novel Role of TRPML2 in the Regulation of the Innate Immune Response.
    Authors: Sun L, Hua Y, Vergarajauregui S, Diab H, Puertollano R
    J Immunol, 2015;195(10):4922-32. 2015
  50. Lysophosphatidic acid alters the expression profiles of angiogenic factors, cytokines, and chemokines in mouse liver sinusoidal endothelial cells.
    Authors: Chou C, Lai S, Ho C, Lin W, Chen C, Lee P, Peng F, Kuo S, Wu S, Lai H
    PLoS ONE, 2015;10(3):e0122060. 2015
  51. The generation of macrophages with anti-inflammatory activity in the absence of STAT6 signaling.
    Authors: Fleming B, Chandrasekaran P, Dillon L, Dalby E, Suresh R, Sarkar A, El-Sayed N, Mosser D
    J Leukoc Biol, 2015;98(3):395-407. 2015
  52. The circadian clock controls sunburn apoptosis and erythema in mouse skin.
    Authors: Gaddameedhi, Shobhan, Selby, Christop, Kemp, Michael, Ye, Rui, Sancar, Aziz
    J Invest Dermatol, 2015;135(4):1119-27. 2015
  53. Targeted Disruption of Ig-Hepta/Gpr116 Causes Emphysema-like Symptoms That Are Associated with Alveolar Macrophage Activation.
    Authors: Ariestanti D, Ando H, Hirose S, Nakamura N
    J Biol Chem, 2015;290(17):11032-40. 2015
  54. Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established disease.
    Authors: Grande M, Sanchez-Laorden B, Lopez-Blau C, De Frutos C, Boutet A, Arevalo M, Rowe R, Weiss S, Lopez-Novoa J, Nieto M
    Nat Med, 2015;21(9):989-97. 2015
  55. Supernatants of tumours treated with chemotherapy can alter tumour growth and development in vivo.
    Authors: Liu W, Scott K, Dalgleish A
    Anticancer Res, 2015;35(3):1499-508. 2015
  56. IkappaBNS regulates murine Th17 differentiation during gut inflammation and infection.
    Authors: Annemann M, Wang Z, Plaza-Sirvent C, Glauben R, Schuster M, Ewald Sander F, Mamareli P, Kuhl A, Siegmund B, Lochner M, Schmitz I
    J Immunol, 2015;194(6):2888-98. 2015
  57. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) prevents lipopolysaccharide (LPS)-induced, sepsis-related severe acute lung injury in mice.
    Authors: Takaoka, Yuki, Goto, Shigeru, Nakano, Toshiaki, Tseng, Hui-Peng, Yang, Shih-Min, Kawamoto, Seiji, Ono, Kazuhisa, Chen, Chao-Lon
    Sci Rep, 2014;4(0):5204. 2014
  58. Absence of fibromodulin affects matrix composition, collagen deposition and cell turnover in healthy and fibrotic lung parenchyma.
    Authors: Rydell-Tormanen K, Andreasson K, Hesselstrand R, Westergren-Thorsson G
    Sci Rep, 2014;4(0):6383. 2014
  59. HPV16-associated tumors control myeloid cell homeostasis in lymphoid organs, generating a suppressor environment for T cells.
    Authors: Stone S, Rossetti R, Bolpetti A, Boccardo E, Souza P, Lepique A
    J Leukoc Biol, 2014;96(4):619-31. 2014
  60. IL-1alpha and complement cooperate in triggering local neutrophilic inflammation in response to adenovirus and eliminating virus-containing cells.
    Authors: Di Paolo N, Baldwin L, Irons E, Papayannopoulou T, Tomlinson S, Shayakhmetov D
    PLoS Pathog, 2014;10(3):e1004035. 2014
  61. Role of Rip2 in development of tumor-infiltrating MDSCs and bladder cancer metastasis.
    Authors: Zhang, Hanwei, Chin, Arnold I
    PLoS ONE, 2014;9(4):e94793. 2014
  62. Human herpesvirus 6A infection in CD46 transgenic mice: viral persistence in the brain and increased production of proinflammatory chemokines via Toll-like receptor 9.
    Authors: Reynaud J, Jegou J, Welsch J, Horvat B
    J Virol, 2014;88(10):5421-36. 2014
  63. The pathogenic mechanism of the Mycobacterium ulcerans virulence factor, mycolactone, depends on blockade of protein translocation into the ER.
    Authors: Hall, Belinda, Hill, Kirsti, McKenna, Michael, Ogbechi, Joy, High, Stephen, Willis, Anne E, Simmonds, Rachel E
    PLoS Pathog, 2014;10(4):e1004061. 2014
  64. Notch-dependent repression of miR-155 in the bone marrow niche regulates hematopoiesis in an NF-kappaB-dependent manner.
    Authors: Wang L, Zhang H, Rodriguez S, Cao L, Parish J, Mumaw C, Zollman A, Kamoka M, Mu J, Chen D, Srour E, Chitteti B, HogenEsch H, Tu X, Bellido T, Boswell H, Manshouri T, Verstovsek S, Yoder M, Kapur R, Cardoso A, Carlesso N
    Cell Stem Cell, 2014;15(1):51-65. 2014
  65. Bone marrow stromal cell-derived exosomes as communicators in drug resistance in multiple myeloma cells.
    Authors: Wang J, Hendrix A, Hernot S, Lemaire M, De Bruyne E, Van Valckenborgh E, Lahoutte T, De Wever O, Vanderkerken K, Menu E
    Blood, 2014;124(4):555-66. 2014
  66. Macrophage-inducing FasL on chondrocytes forms immune privilege in cartilage tissue engineering, enhancing in vivo regeneration.
    Authors: Fujihara Y, Takato T, Hoshi K
    Stem Cells, 2014;32(5):1208-19. 2014
  67. Periostin controls keratinocyte proliferation and differentiation by interacting with the paracrine IL-1alpha/IL-6 loop.
    Authors: Taniguchi K, Arima K, Masuoka M, Ohta S, Shiraishi H, Ontsuka K, Suzuki S, Inamitsu M, Yamamoto K, Simmons O, Toda S, Conway S, Hamasaki Y, Izuhara K
    J Invest Dermatol, 2014;134(5):1295-304. 2014
  68. BMP pathway regulation of and by macrophages.
    Authors: Talati M, West J, Zaynagetdinov R, Hong C, Han W, Blackwell T, Robinson L, Blackwell T, Lane K
    PLoS ONE, 2014;9(4):e94119. 2014
  69. A paracrine network regulates the cross-talk between human lung stem cells and the stroma.
    Authors: Ruiz E, Oeztuerk-Winder F, Ventura J
    Nat Commun, 2014;5(0):3175. 2014
  70. Sc65 is a novel endoplasmic reticulum protein that regulates bone mass homeostasis.
    Authors: Gruenwald K, Castagnola P, Besio R, Dimori M, Chen Y, Akel N, Swain F, Skinner R, Eyre D, Gaddy D, Suva L, Morello R
    J Bone Miner Res, 2014;29(3):666-75. 2014
  71. The Src family kinases Hck, Fgr, and Lyn are critical for the generation of the in vivo inflammatory environment without a direct role in leukocyte recruitment.
    Authors: Kovacs M, Nemeth T, Jakus Z, Sitaru C, Simon E, Futosi K, Botz B, Helyes Z, Lowell C, Mocsai A
    J Exp Med, 2014;211(10):1993-2011. 2014
  72. Metabolic reprogramming of macrophages: glucose transporter 1 (GLUT1)-mediated glucose metabolism drives a proinflammatory phenotype.
    Authors: Freemerman A, Johnson A, Sacks G, Milner J, Kirk E, Troester M, Macintyre A, Goraksha-Hicks P, Rathmell J, Makowski L
    J Biol Chem, 2014;289(11):7884-96. 2014
  73. Effects of insulin resistance on skeletal muscle growth and exercise capacity in type 2 diabetic mouse models.
    Authors: Ostler, Joseph E, Maurya, Santosh, Dials, Justin, Roof, Steve R, Devor, Steven T, Ziolo, Mark T, Periasamy, Muthu
    Am J Physiol Endocrinol Metab, 2014;306(6):E592-605. 2014
  74. Infection with Leishmania major induces a cellular stress response in macrophages.
    Authors: Filardy A, Costa-da-Silva A, Koeller C, Guimaraes-Pinto K, Ribeiro-Gomes F, Lopes M, Heise N, Freire-de-Lima C, Nunes M, DosReis G
    PLoS ONE, 2014;9(1):e85715. 2014
  75. Cancer affects microRNA expression, release, and function in cardiac and skeletal muscle.
    Authors: Chen D, Goswami C, Burnett R, Anjanappa M, Bhat-Nakshatri P, Muller W, Nakshatri H
    Cancer Res, 2014;74(16):4270-81. 2014
  76. IL-15 deficient tax mice reveal a role for IL-1alpha in tumor immunity.
    Authors: Rauch D, Harding J, Ratner L
    PLoS ONE, 2014;9(1):e85028. 2014
  77. Dystrophic mdx mice develop severe cardiac and respiratory dysfunction following genetic ablation of the anti-inflammatory cytokine IL-10.
    Authors: Nitahara-Kasahara Y, Hayashita-Kinoh H, Chiyo T, Nishiyama A, Okada H, Takeda S, Okada T
    Hum Mol Genet, 2014;23(15):3990-4000. 2014
  78. Novel mechanisms underlying the immediate and transient global tolerization of splenic dendritic cells after vaccination with a self-antigen.
    Authors: Farkas A, Finn O
    J Immunol, 2014;192(2):658-65. 2014
  79. Improving membrane based multiplex immunoassays for semi-quantitative detection of multiple cytokines in a single sample.
    Authors: Altara, Raffaele, Manca, Marco, Hessel, Marleen, Janssen, Ben J, Struijker-Boudier, Harry H, Hermans, Rob J J, Blankesteijn, W Matthi
    BMC Biotechnol, 2014;14(0):63. 2014
  80. Regulation of adult hematopoiesis by the a disintegrin and metalloproteinase 10 (ADAM10).
    Authors: Weber S, Wetzel S, Prox J, Lehmann T, Schneppenheim J, Donners M, Saftig P
    Biochem Biophys Res Commun, 2013;442(3):234-41. 2013
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  84. Anticancer compound ABT-263 accelerates apoptosis in virus-infected cells and imbalances cytokine production and lowers survival rates of infected mice.
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  99. The MSHA Strain of Pseudomonas Aeruginosa Activated TLR Pathway and Enhanced HIV-1 DNA Vaccine Immunoreactivity.
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  105. CX3CL1 expression in the conjunctiva is involved in immune cell trafficking during toxic ocular surface inflammation.
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    Mucosal Immunol, 2012;5(0):702. 2012
  106. Murine bone marrow-derived macrophages differentiated with GM-CSF become foam cells by PI3Kgamma-dependent fluid-phase pinocytosis of native LDL.
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    Cancer Res, 2012;72(22):5721-32. 2012
  108. Dietary blue pigments derived from genipin, attenuate inflammation by inhibiting LPS-induced iNOS and COX-2 expression via the NF-kappaB inactivation.
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    PLoS ONE, 2012;7(3):e34122. 2012
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    Blood, 2011;118(18):5031-9. 2011
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    J. Lipid Res., 2011;52(7):1307-18. 2011
  111. Involvement of adenosine A2A receptors in engulfment-dependent apoptotic cell suppression of inflammation.
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    J. Immunol., 2011;186(12):7144-55. 2011
  112. Stromal interaction essential for vascular endothelial growth factor A-induced tumour growth via transforming growth factor-beta signalling.
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    Br. J. Cancer, 2011;105(12):1856-63. 2011
  113. Reduced VEGF production, angiogenesis, and vascular regrowth contribute to the antitumor properties of dual mTORC1/mTORC2 inhibitors.
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    Mol. Cell. Biol., 2011;31(5):971-82. 2011
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