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149 results for "KOR" in Products

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KOR Products

Kappa Opioid Receptor (KOR) is a 45 kDa 7TM opioid receptor that is primarily expressed in the central nervous system and peripheral visceral pain sensory nerves. Following ligation by dynorphin peptides, KOR signaling induces analgesia, dysphoria, diuresis, and increased feeding desire. KOR also exerts neuroprotective and anti-inflammatory effects. Human KOR shares 94% amino acid sequence identity with mouse and rat KOR.

(±)-U-50488 hydrochloride

Catalog #: 0495
(4)
Citations (20)
Product Documents

Selective κ agonist

Chemical Name: trans-(±)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide hydrochloride
Purity: ≥99%
Selective κ agonist

Human KOR Antibody

Catalog #: MAB3895
(1)
Citations (1)
Product Documents
Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #387301
Applications: Flow, ICC/IF, CyTOF-ready

Human KOR Antibody

Catalog #: MAB38951
Citations (1)
Product Documents
Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #387310
Applications: IHC
KOR antibody in Human Brainstem by Immunohistochemistry (IHC-P).

(-)-U-50488 hydrochloride

Catalog #: 0496
(3)
Citations (21)
Product Documents

Selective κ agonist; more active enantiomer of (±)-U-50488 (Cat. No. 0495)

Chemical Name: trans-(-)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide hydrochloride
Purity: ≥99%
Selective κ agonist; more active enantiomer of (±)-U-50488 (Cat. No. 0495)

Dynorphin A

Catalog #: 3195
(1)
Citations (42)
Product Documents

Endogenous κ agonist

Purity: ≥95%
Endogenous κ agonist

Salvinorin B

Catalog #: 5611
(1)
Citations (12)
Product Documents

Activator of κ-opioid DREADD (KORD)

Chemical Name: (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(3-Furanyl)dodecahydro-9-hydroxy-6a,10b-dimethyl-4,10-dioxo-2H-naphtho[2,1-c]pyran-7-carboxylic acid methyl ester
Purity: ≥98%
Activator of κ-opioid DREADD (KORD)

Nalmefene hydrochloride

Catalog #: 4085
Citations (10)
Product Documents

Opioid receptor antagonist

Chemical Name: (5α)-17-(Cyclopropylmethyl)-4,5-epoxy-6-methylenemorphinan-3,14-diol hydrochloride
Purity: ≥98%
Opioid receptor antagonist

Rat KOR Antibody

Catalog #: MAB8867
Product Documents

Recombinant Monoclonal Antibody.

Reactivity: Rat
Details: Rabbit IgG Monoclonal Clone #1123A
Applications: ICC/IF
KOR antibody in CHO Chinese Hamster Cell Line by Immunocytochemistry (ICC).

(+)-U-50488 hydrochloride

Catalog #: 0471
(1)
Product Documents

Selective κ agonist; less active enantiomer of (±)-U-50488 (Cat. No. 0495)

Chemical Name: trans-(+)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)-cyclohexyl]benzeneacetamide hydrochloride
Purity: ≥99%
Selective κ agonist; less active enantiomer of (±)-U-50488 (Cat. No. 0495)

DIPPA hydrochloride

Catalog #: 0794
Citations (1)
Product Documents

Selective and irreversible κ antagonist

Chemical Name: 2-(3,4-Dichlorophenyl)-N-methyl-N-[(1S)-1-(3-isothiocyanatophenyl)-2-(1-pyrrolidinyl)ethyl]acetamide hydrochloride
Purity: ≥98%
Selective and irreversible κ antagonist

ICI 204,448 hydrochloride

Catalog #: 0822
(1)
Citations (6)
Product Documents

κ agonist, acts peripherally

Chemical Name: (RS)-[3-[1-[[(3,4-Dichlorophenyl)acetyl]methylamino]-2-(1-pyrrolidinyl)ethyl]phenoxy]acetic acid hydrochloride
Purity: ≥98%
κ agonist, acts peripherally

GR 89696 fumarate

Catalog #: 1483
Citations (4)
Product Documents

Subtype-selective κ agonist

Chemical Name: 4-[(3,4-Dichlorophenyl)acetyl]-3-(1-pyrrolidinylmethyl)-1-piperazinecarboxylic acid methyl ester fumarate
Purity: ≥99%
Subtype-selective κ agonist

ML 190

Catalog #: 4866
Citations (2)
Product Documents

Selective κ opioid receptor antagonist

Chemical Name: N-[3-[4-(4-Methoxyphenyl)-1-piperazinyl]propyl]-1-methyl-6-oxopyrido[2,3-e]pyrrolo[1,2-a]pyrazine-5(6H)-acetamide
Purity: ≥98%
Selective κ opioid receptor antagonist

KOR Antibody

Catalog #: NBP1-68860
Citations (2)
Product Documents
Reactivity: Human
Details: Goat IgG Polyclonal
Applications: WB, ELISA, ICC/IF
Western Blot: KOR Antibody [NBP1-68860]

Human KOR (NP_000903) VersaClone cDNA

Catalog #: RDC0145
Product Documents
Reactivity: Human
R&D Systems VersaClone cDNA Plasmids

Rat KOR (NP_058863) VersaClone cDNA

Catalog #: RDC0433
Product Documents
Reactivity: Rat
R&D Systems VersaClone cDNA Plasmids

KOR Antibody - BSA Free

Catalog #: NLS228
Product Documents
Reactivity: Human, Rat, Canine, Equine, Monkey, +1 More
Details: Rabbit IgG Polyclonal
Applications: IHC
Immunohistochemistry-Paraffin: KOR Antibody - BSA Free [NLS228]

KOR Antibody - BSA Free

Catalog #: NBP2-68859
Product Documents
Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: ICC/IF
Immunocytochemistry/ Immunofluorescence: KOR Antibody [NBP2-68859]

Human KOR Alexa Fluor® 488‑conjugated Antibody

Catalog #: FAB38951G
Product Documents
Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #387310
Applications: IHC
Human KOR Alexa Fluor® 488‑conjugated Antibody

Human KOR Alexa Fluor® 700‑conjugated Antibody

Catalog #: FAB38951N
Product Documents
Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #387310
Applications: IHC
Human KOR Alexa Fluor® 700‑conjugated Antibody

Human KOR Alexa Fluor® 647‑conjugated Antibody

Catalog #: FAB38951R
Product Documents
Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #387310
Applications: IHC
Human KOR Alexa Fluor® 647‑conjugated Antibody

Human KOR Alexa Fluor® 750‑conjugated Antibody

Catalog #: FAB38951S
Product Documents
Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #387310
Applications: IHC
Human KOR Alexa Fluor® 750‑conjugated Antibody

Human KOR Alexa Fluor® 594‑conjugated Antibody

Catalog #: FAB38951T
Product Documents
Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #387310
Applications: IHC
Human KOR Alexa Fluor® 594‑conjugated Antibody

Human KOR Alexa Fluor® 350‑conjugated Antibody

Catalog #: FAB38951U
Product Documents
Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #387310
Applications: IHC
Human KOR Alexa Fluor® 350‑conjugated Antibody

Human KOR Alexa Fluor® 405‑conjugated Antibody

Catalog #: FAB38951V
Product Documents
Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #387310
Applications: IHC
Human KOR Alexa Fluor® 405‑conjugated Antibody
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