KOR in CHO Chinese Hamster Cell Line.
KOR was detected in immersion fixed CHO Chinese hamster ovary cell line transfected with KOR using Rabbit Anti-Rat KOR Monoclonal Antibody (Catalog # MAB8867) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Rabbit IgG Secondary Antibody (red; Catalog # NL004) and counterstained with DAPI (blue). Specific staining was localized to plasma membrane and cytoplasm. View our protocol for Fluorescent ICC Staining of Cells on Coverslips.
Preparation and Storage
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 °C, as supplied.
1 month, 2 to 8 °C under sterile conditions after opening.
6 months, -20 to -70 °C under sterile conditions after opening.
KOR is a 45 kDa 7TM opioid receptor that is primarily expressed in the
central nervous system and peripheral visceral pain sensory nerves.
Following ligation by dynorphin peptides, KOR signaling induces
analgesia, dysphoria, diuresis, and increased feeding desire. KOR also
exerts neuroprotective and anti-inflammatory effects. Human KOR shares
94% amino acid sequence identity with mouse and rat KOR.
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