9 results for "Kv7.2 Small Molecules and Peptides" in Products

Kv7.2 Small Molecules and Peptides

KCNQs are members of the voltage dependent non inactivating potassium channel family. Currently there are five known KCNQs (KCNQ1 to 5) found in the central nervous system and KCNQ2 and 3 have demonstrated their importance in M current activation. Studies have shown that KCNQ2 and KCNQ3 form heteromultimers that, when formed, substantially increas...

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KV7.2 and KV7.4 channel opener

Chemical Name: N-(2,4,6-Trimethylphenyl)-bicyclo[2.2.1]heptane-2-carboxamide
Purity: ≥99%
KV7.2 and KV7.4 channel opener
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Kv7 channel opener

Chemical Name: 5-(2,6-Dichloro-5-fluoro-3-pyridinyl)-3-phenyl-2-(trifluoromethyl)-pyrazolo[1,5-a]pyrimidin-7(4H)-one
Purity: ≥98%
Kv7 channel opener
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KV7.2/7.3 activator; displays anticonvulsant properties

Chemical Name: 4-Chloro-N-(6-chloro-3-pyridinyl)benzamide
Purity: ≥98%
KV7.2/7.3 activator; displays anticonvulsant properties
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Potassium channel modulator; exerts subtype-specific effects

Chemical Name: (3S)-3-(5-Chloro-2-methoxyphenyl)-3-fluoro-1,3-dihydro-6-(trifluoromethyl)-2H-Indol-2-one
Purity: ≥98%
Potassium channel modulator; exerts subtype-specific effects
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Potent and selective KV7.2 inhibitor; brain penetrant

Chemical Name: (S)-2-Phenyl-N-(2-(pyrrolidin-1-yl)phenyl)butanamide
Purity: ≥98%
Potent and selective KV7.2 inhibitor; brain penetrant
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KV7 (KCNQ) channel blocker

Alternate Names: DuP 996
Chemical Name: 1,3-Dihydro-1-phenyl-3,3-bis(4-pyridinylmethyl)-2H-indol-2-one dihydrochloride
Purity: ≥98%
KV7 (KCNQ) channel blocker
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KV7.2/KV7.3 channel opener

Chemical Name: N-(2-Chloro-5-pyrimidinyl)-3,4-difluorobenzamide
Purity: ≥99%
KV7.2/KV7.3 channel opener
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KV7 channel activator; also GABAA modulator and indirect NMDA antagonist

Alternate Names: D 9998
Chemical Name: N-[2-Amino-6-[[4-fluorophenyl)methyl]amino]-3-pyridinyl]carbamic acid ethyl ester maleate
Purity: ≥98%
KV7 channel activator; also GABAA modulator and indirect NMDA antagonist
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KCNQ2 activator

Chemical Name: N-(1,2-Dihydro-5-acenaphthylenyl)-4-fluorobenzamide
Purity: ≥98%
KCNQ2 activator
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