Having trouble trying to find the right product? Chat with our scientists below - we're here to help!
810 results for "LAG-3" in Products
LAG-3 Products
LAG-3 (Lymphocyte activation gene-3; CD223) is a transmembrane protein that binds to MHC class II molecules and negatively regulates T cell receptor signaling. It is expressed on activated T cells, NK cells, and plasmacytoid dendritic cells (pDC). LAG-3 limits the expansion of activated T cells and pDC in response to select stimuli. Proteolytic shedding of LAG-3 enables normal T cell activation by removing the negative regulation. Binding of a homodimerized soluble LAG-3/Ig fusion protein to MHC class II molecules induces maturation of immature DC as well as secretion of pro-inflammatory cytokines by cytotoxic CD8+ T cells and NK cells.
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | Flow |
Loading...
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, Flow, CyTOF-ready |
Loading...
| Reactivity: | Human |
| Source: | CHO |
| Accession #: | P18627 |
| Applications: | Bioactivity |
Loading...
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB |
Loading...
| Reactivity: | Human |
| Source: | NS0 |
| Accession #: | P18627 |
| Applications: | Bioactivity |
Loading...
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #874501 |
| Applications: | WB, Flow, CyTOF-ready |
Loading...
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #BLR027F |
| Applications: | mIF, IHC, WB, Flow, ICC/IF, + 1 More |
![Western Blot: LAG-3 Antibody (BLR027F) [NBP2-76402]](https://resources.rndsystems.com/images/products/LAG-3-Antibody-BLR027F-Western-Blot-NBP2-76402-img0007.jpg "Western Blot: LAG-3 Antibody (BLR027F) [NBP2-76402]")
Loading...
| Reactivity: | Human |
| Applications: | Simple Plex |
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #BLR028F |
| Applications: | IHC, WB, ICC/IF, IP |
![Western Blot: LAG-3 Antibody (BLR028F) [NBP2-76403]](https://resources.rndsystems.com/images/products/LAG-3-Antibody-BLR028F-Western-Blot-NBP2-76403-img0003.jpg "Western Blot: LAG-3 Antibody (BLR028F) [NBP2-76403]")
Loading...
| Reactivity: | Human |
| Applications: | IHC, WB, Flow |
![Flow Cytometry: LAG-3 Antibody Pack [NBP3-11743]](https://resources.rndsystems.com/images/products/LAG-3-Antibody-Pack-Flow-Cytometry-NBP3-11743-img0001.jpg "Flow Cytometry: LAG-3 Antibody Pack [NBP3-11743]")
Loading...
| Reactivity: | Human, Monkey |
| Details: | Mouse IgG1 Monoclonal Clone #11E3 |
| Applications: | IHC, WB, ELISA, Flow, ICC/IF, + 1 More |
![Flow Cytometry: LAG-3 Antibody (11E3) - BSA Free [NBP1-97662]](https://resources.rndsystems.com/images/products/LAG-3-Antibody-11E3-Flow-Cytometry-NBP1-97662-img0001.jpg "Flow Cytometry: LAG-3 Antibody (11E3) - BSA Free [NBP1-97662]")
Loading...
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #874512 |
| Applications: | IHC, Flow, CyTOF-ready |
Loading...
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #1009611 |
| Applications: | WB, Flow, CyTOF-ready |
Loading...
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #874528 |
| Applications: | IHC, Flow, CyTOF-ready |
Loading...
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: LAG-3 Antibody [NBP1-85781]](https://resources.rndsystems.com/images/products/LAG-3-Antibody-Immunohistochemistry-Paraffin-NBP1-85781-img0007.jpg "Immunohistochemistry-Paraffin: LAG-3 Antibody [NBP1-85781]")
Loading...
| Reactivity: | Human, Primate |
| Details: | Mouse IgG1 kappa Monoclonal Clone #L4-PL33 |
| Applications: | IHC, WB, ELISA, Flow, ICC/IF, + 1 More |
Loading...
| Reactivity: | Human |
| Assay Range: | 93.8-6000 pg/mL |
| Applications: | ELISA |
Loading...
| Reactivity: | Mouse |
| Details: | Rat IgG2B Monoclonal Clone #631501 |
| Applications: | Flow, CyTOF-ready |
Loading...
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #L4-PL33 |
| Applications: | IHC, WB, ELISA, Flow, ICC/IF, + 1 More |
![Western Blot: LAG-3 Antibody (L4-PL33)Azide Free [NBP3-05777]](https://resources.rndsystems.com/images/products/LAG-3-Antibody-L4-PL33-Azide-Free-Western-Blot-NBP3-05777-img0001.jpg "Western Blot: LAG-3 Antibody (L4-PL33)Azide Free [NBP3-05777]")
Loading...
| Reactivity: | Cynomolgus Monkey |
| Source: | CHO |
| Accession #: | XP_005570011.1 |
| Applications: | Bioactivity |
Loading...
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #1009614 |
| Applications: | Flow, CyTOF-ready |
Loading...
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #1058221 |
| Applications: | IHC, ICC/IF |
Loading...
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #OTI8F6 |
| Applications: | IHC, WB, Flow |
![Western Blot: LAG-3 Antibody (OTI8F6) [NBP2-45581]](https://resources.rndsystems.com/images/products/LAG-3-Antibody-OTI8F6-Western-Blot-NBP2-45581-img0004.jpg "Western Blot: LAG-3 Antibody (OTI8F6) [NBP2-45581]")
Loading...
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #OTI8F6 |
| Applications: | IHC, WB, Flow |
![Western Blot: LAG-3 Antibody (OTI8F6)Azide and BSA Free [NBP2-71112]](https://resources.rndsystems.com/images/products/LAG-3-Antibody-OTI8F6-Azide-and-BSA-Free-Western-Blot-NBP2-71112-img0001.jpg "Western Blot: LAG-3 Antibody (OTI8F6)Azide and BSA Free [NBP2-71112]")
Loading...
| Reactivity: | Human |
| Details: | Llama Monoclonal Clone #2A11 |
| Applications: | IHC, ELISA, Flow, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: LAG-3 Antibody (2A11) - VHH - Azide and BSA Free [NBP3-12836]](https://resources.rndsystems.com/images/products/LAG-3-Antibody-2A11-VHH-Immunocytochemistry-Immunofluorescence-NBP3-12836-img0004.jpg "Immunocytochemistry/ Immunofluorescence: LAG-3 Antibody (2A11) - VHH - Azide and BSA Free [NBP3-12836]")
Loading...