144 results for "PAR1" in Products

PAR1 Products

Human Proteinase-Activated Receptor 1 (hPAR1), also known as thrombin receptor, is a 65-70 kDa, 399 amino acid long member of the seven-transmembrane superfamily of cell-surface G protein-coupled receptors. PAR1 is activated by thrombin cleavage of its N-terminal propeptide in the extracellular domain. Human PAR1 is widely expressed in many cell types including endothelial cells, and it has been implicated in a variety of inflammatory responses. Over the regions used as immunogen, human and mouse PAR1 proteins are 58% identical in the region spanning the propeptide and extracellular domains, and 84% identical in the cytoplasmic tail.

Reactivity: Human, Mouse
Details: Mouse IgG1 Monoclonal Clone #N2-11
Applications: IHC, WB, ELISA, ICC/IF
Immunohistochemistry: PAR1/Thrombin Receptor Antibody (N2-11) [NBP1-71770]
(8)
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Potent, selective non-peptide PAR1 antagonist

Chemical Name: N3-Cyclopropyl-7-[[4-(1-methylethyl)phenyl]methyl]-7H-pyrrolo[3,2-f]quinazoline-1,3-diamine dihydrochloride
Purity: ≥98%
Potent, selective non-peptide PAR1 antagonist
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Reactivity: Human
Details: Mouse IgG2B Monoclonal Clone #731115
Applications: IHC, WB, Flow, CyTOF-ready
Detection of Human PAR1 antibody by Western Blot.
(4)
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Reactivity: Human, Mouse
Details: Mouse IgG1 Monoclonal Clone #N2-11
Applications: IHC, WB, ELISA, ICC/IF
Western Blot: PAR1/Thrombin Receptor Antibody (N2-11)Azide and BSA Free [NBP2-80904]
(4)
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PAR1-activating peptide

Purity: ≥95%
PAR1-activating peptide
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PAR1 peptide fragment (residues 42-47); acts as a PAR1 agonist

Alternate Names: Thrombin receptor activator peptide 6
Purity: ≥95%
PAR1 peptide fragment (residues 42-47); acts as a PAR1 agonist
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Reactivity: Human
Details: Mouse IgG2B Monoclonal Clone #731115
Applications: Flow
Detection of PAR1 antibody in HT‑29 Human Cell Line antibody by Flow Cytometry.
(2)
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Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #5E2E6
Applications: IHC, WB, ELISA
Western Blot: PAR1/Thrombin Receptor Antibody (5E2E6)BSA Free [NBP2-61770]
(4)
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Tryptase inhibitor

Chemical Name: N-(1-Hydroxy-2-naphthoyl)-L-arginyl-L-prolinamide
Purity: ≥95%
Tryptase inhibitor
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PAR1 antagonist

Chemical Name: 2-[3-(4-Chlorophenyl)-2-[(2,4-dichlorobenzoyl)imino]-4-oxo-5-thiazolidinylidene]-acetic acid methyl ester
Purity: ≥98%
PAR1 antagonist
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Reactivity: Human
R&D Systems VersaClone cDNA Plasmids
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Reactivity: Mouse
R&D Systems VersaClone cDNA Plasmids
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Reactivity: Human
Details: Mouse IgG2B Monoclonal Clone #731115
Applications: Flow
Detection of PAR1 antibody in Human Peripheral Blood Platelets antibody by Flow Cytometry.
(2)
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Reactivity: Human
Details: Mouse IgG2B Monoclonal Clone #731115
Applications: Flow
Detection of PAR1 antibody in Human Peripheral Blood Platelets antibody by Flow Cytometry.
(2)
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Reactivity: Human
Details: Goat IgG Polyclonal
Applications: WB, ELISA
Western Blot: PAR1/Thrombin Receptor Antibody [NBP1-51936]
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