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233 results for "R-Spondin 1" in Products
R-Spondin 1 Products
R-Spondin 1 (RSPO1), also known as Cristin 3, is a 27 kDa secreted protein in the R-Spondin family of Wnt/beta-catenin signaling regulators. R-Spondin 1 enhances canonical Wnt/beta-catenin signaling by competing with the Wnt antagonist Dkk-1, binding to Frizzled-8, Kremen, LRP-6, Lgr4, Lgr5, and Lgr6, and enhancing cell surface availability of Wnt receptors. R-Spondin 1 functions in dorsal neural tube development as well as male and female germ cell development. It also induces bone formation, intestinal crypt cell proliferation, angiogenesis, and insulin secretion from pancreatic beta cells.
| Reactivity: | Human |
| Source: | CHO |
| Accession #: | Q2MKA7 |
| Applications: | Bioactivity |
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| Reactivity: | Mouse |
| Source: | CHO |
| Accession #: | NP_619624 |
| Applications: | Bioactivity |
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| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB |
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| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
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| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2B Monoclonal Clone #422407 |
| Applications: | WB |
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| Reactivity: | Human |
| Assay Range: | 31.2-2000 pg/mL |
| Applications: | ELISA |
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| Reactivity: | Mouse |
| Source: | CHO |
| Applications: | Bioactivity |
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| Reactivity: | Human |
| Source: | E. coli |
| Accession #: | Q2MKA7.1 |
| Applications: | Bioactivity |
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| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | B/N |
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| Reactivity: | Mouse |
| Details: | Rat IgG2B Monoclonal Clone #852010 |
| Applications: | B/N |
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| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #OTI11A9 |
| Applications: | IHC, WB |
![Western Blot: R-Spondin 1 Antibody (OTI11A9) [NBP2-45636]](https://resources.rndsystems.com/images/products/R-Spondin-1-Antibody-11A9-Western-Blot-NBP2-45636-img0002.jpg "Western Blot: R-Spondin 1 Antibody (OTI11A9) [NBP2-45636]")
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| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #OTI11A9 |
| Applications: | IHC, WB |
![Western Blot: R-Spondin 1 Antibody (OTI11A9)Azide and BSA Free [NBP2-73948]](https://resources.rndsystems.com/images/products/R-Spondin-1-Antibody-OTI11A9-Azide-and-BSA-Free-Western-Blot-NBP2-73948-img0001.jpg "Western Blot: R-Spondin 1 Antibody (OTI11A9)Azide and BSA Free [NBP2-73948]")
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| Reactivity: | Cynomolgus Monkey |
| Applications: |
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| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB |
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| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB |
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| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB |
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| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB |
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| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB |
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| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB |
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| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB |
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| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB |
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| Reactivity: | Human |
| Source: | CHO |
| Accession #: | Q2MKA7.1 |
| Applications: | Bioactivity |
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| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2B Monoclonal Clone #422407 |
| Applications: | WB |
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| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2B Monoclonal Clone #422407 |
| Applications: | WB |
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| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2B Monoclonal Clone #422407 |
| Applications: | WB |
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