Having trouble trying to find the right product? Chat with our scientists below - we're here to help!
47 results for "Tankyrase 1" in Products
Tankyrase 1 Products
The ~142 kDa Tankyrase protein is ubiquitously expressed in mammalian cells and is localized to human telomeres. It has homology to ankyrins and to the catalytic domain of poly (adenosine diphosphate-ribose) polymerase (PARP). Tankyrase binds to TRF1 (telomeric repeat binding factor-1), which negatively regulates the maintenance of telomere length.
Potent tankyrase inhibitor
GMP Version Available:
TB3748-GMP
GMP
| Alternate Names: | XAV939 Wnt Signaling Inhibitor |
| Chemical Name: | 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one |
| Purity: | ≥98% |
Loading...
Wnt/β-catenin signaling inhibitor; axin stabilizer
| Chemical Name: | rel-4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide |
| Purity: | ≥98% |
Loading...
XAV 939 synthesized to cGMP guidelines
| Chemical Name: | 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one |
| Purity: | ≥99% |
Loading...
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
Loading...
| Reactivity: | Human, Monkey |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: Tankyrase 1 Antibody [NBP2-20559]](https://resources.rndsystems.com/images/products/Tankyrase-Antibody-Western-Blot-NBP2-20559-img0001.jpg "Western Blot: Tankyrase 1 Antibody [NBP2-20559]")
Loading...
Potent PARP inhibitor
| Chemical Name: | N-(5,6-Dihydro-6-oxo-2-phenanthridinyl)-2-acetamide hydrochloride |
| Purity: | ≥98% |
Loading...
Potent TNKS1/2 inhibitor
| Chemical Name: | rel-2-[4-[6-[(3R,5S)-3,5-Dimethyl-1-piperazinyl]-4-methyl-3-pyridinyl]phenyl]-3,7-dihydro-7-methyl-4H-pyrrolo[2,3-d]pyrimidin-4-one |
| Purity: | ≥98% |
Loading...
Potent tankyrase inhibitor
| Chemical Name: | 2-[3-[[4-(4-Methoxyphenyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]propyl]-1H-benz[de]isoquinoline-1,3(2H)-dione |
| Purity: | ≥98% |
Loading...
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: Tankyrase 1 Antibody [NBP1-80947]](https://resources.rndsystems.com/images/products/Tankyrase-1-Antibody-Immunocytochemistry-Immunofluorescence-NBP1-80947-img0006.jpg "Immunocytochemistry/ Immunofluorescence: Tankyrase 1 Antibody [NBP1-80947]")
Loading...
Tankyrase (AKA PARP5) inhibitor; used to generate neurons from epiblast stem cells
| Chemical Name: | N-(Cyclopropylmethyl)-4-(4-methoxybenzoyl)-N-[(3,5,7,8-tetrahydro-4-oxo-4H-pyrano[4,3-d]pyrimidin-2-yl)methyl]-1-piperidineacetamide |
| Purity: | ≥98% |
Loading...
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, IP |
Loading...
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
![Western Blot: Tankyrase 1 Antibody [NBP1-36994]](https://resources.rndsystems.com/images/products/Tankyrase-1-Antibody-Western-Blot-NBP1-36994-img0005.jpg "Western Blot: Tankyrase 1 Antibody [NBP1-36994]")
Loading...
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #PSH0-51 |
| Applications: | WB |
Loading...
| Reactivity: | Human |
| Sensitivity: | 37.50 pg/mL |
| Assay Range: | 62.50-4000 pg/mL |
| Applications: | ELISA |
Loading...
| Reactivity: | Human |
| Sensitivity: | 0.19 ng/mL |
| Assay Range: | 0.31 - 20 ng/mL |
| Applications: | ELISA |
Loading...
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
Loading...
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
Loading...
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
Loading...
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
Loading...
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
Loading...
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
Loading...
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
Loading...
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
Loading...
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IP |
Loading...
| Reactivity: | Human |
| Source: | E. coli |
| Applications: | AC |
Loading...