58 results for "TRPA1" in Products
TRPA1 Products
Transient receptor potential ion channels (TRPCs) are a superfamily of six transmembrane segment-spanning, gated cation channels. TRPA1 is a TRP-related channel that responds to cold temperatures and pungent compounds and plays a role in both nociceptor and hair cell transduction. It is a transformation-associated gene product in lung epithelia, whereas its protein distribution is primarily restricted to sensory neurons. Blocking TRPA1 may be a therapeutic target for treating cold hyperalgesia caused by inflammation and nerve damage. It is now known that TRPA1 protein is also widely expressed outside of the CNS and is dys-regulated during oncogenic transformation.
| Reactivity: | Human, Mouse, Rat, Guinea Pig, Zebrafish |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, Flow, ICC/IF |
![Western Blot: TRPA1 AntibodyBSA Free [NB110-40763]](https://resources.rndsystems.com/images/products/TRPA1-Antibody-Western-Blot-NB110-40763-img0014.jpg "Western Blot: TRPA1 AntibodyBSA Free [NB110-40763]")
| Reactivity: | Human, Mouse, Rat, Monkey |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: TRPA1 Antibody [NB100-91319]](https://resources.rndsystems.com/images/products/TRPA1-Antibody-Western-Blot-NB100-91319-img0001.jpg "Western Blot: TRPA1 Antibody [NB100-91319]")
| Reactivity: | Human, Mouse, Guinea Pig |
| Details: | Mouse IgG1 kappa Monoclonal Clone #6G8 |
| Applications: | IHC, WB, ELISA |
![Western Blot: TRPA1 Antibody (6G8) [H00008989-M03]](https://resources.rndsystems.com/images/products/TRPA1-Antibody-6G8-Western-Blot-H00008989-M03-img0004.jpg "Western Blot: TRPA1 Antibody (6G8) [H00008989-M03]")
| Reactivity: | Mouse, Rat, Guinea Pig |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: TRPA1 Antibody [NB100-98841]](https://resources.rndsystems.com/images/products/TRPA1-Antibody-Immunocytochemistry-Immunofluorescence-NB100-98841-img0001.jpg "Immunocytochemistry/ Immunofluorescence: TRPA1 Antibody [NB100-98841]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Immunohistochemistry: TRPA1 Antibody [NBP3-10359]](https://resources.rndsystems.com/images/products/TRPA1-Antibody-Immunohistochemistry-NBP3-10359-img0001.jpg "Immunohistochemistry: TRPA1 Antibody [NBP3-10359]")
| Reactivity: | Human |
| Applications: |
| Reactivity: | Drosophila |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
| Reactivity: | Human |
| Source: | Wheat germ |
| Applications: | WB, ELISA, AP, MA, PAGE |
![SDS-PAGE: Recombinant Human TRPA1 GST (N-Term) Protein [H00008989-Q01]](https://resources.rndsystems.com/images/products/qc_test-H00008989-Q01-1.jpg "SDS-PAGE: Recombinant Human TRPA1 GST (N-Term) Protein [H00008989-Q01]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: TRPA1 Antibody [H00008989-D01P]](https://resources.rndsystems.com/images/products/TRPA1-Antibody-Western-Blot-H00008989-D01P-img0002.jpg "Western Blot: TRPA1 Antibody [H00008989-D01P]")
| Reactivity: | Human |
| Sensitivity: | 0.214 ng/mL (example only; lot dependent) |
| Assay Range: | 0.625 - 40 ng/mL (example only; lot dependent) |
| Applications: | ELISA |
| Reactivity: | Human |
| Sensitivity: | 0.214 ng/mL (example only; lot dependent) |
| Assay Range: | 0.625 - 40 ng/mL (example only; lot dependent) |
| Applications: | ELISA |
| Reactivity: | Human |
| Applications: | WB |
| Reactivity: | Rat |
| Applications: | AC |
Activates cold receptors. Cooling agent
| Alternate Names: | AG 3-5 |
| Chemical Name: | 3,4-Dihydro-3-(2-hydroxyphenyl)-6-(3-nitrophenyl)-(1H)-pyrimidin-2-one |
| Purity: | ≥98% |
Selective TRPA1 blocker
| Chemical Name: | 2-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide |
| Purity: | ≥98% |
Selective TRPA1 channel blocker
| Alternate Names: | A-079 |
| Chemical Name: | (1E,3E)-1-(4-Fluorophenyl)-2-methyl-1-pentene-3-one oxime |
| Purity: | ≥98% |
Potent and selective TRPA1 channel activator
| Chemical Name: | 2-Chloro-N-[4-(4-methoxyphenyl)-2-thiazolyl]-N-(3-methoxypropyl)acetamide |
| Purity: | ≥98% |
Cyclooxygenase inhibitor
| Chemical Name: | 5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3,benzenediol |
| Purity: | ≥98% |
Potent and selective FAAH inhibitor
| Chemical Name: | Cyclohexylcarbamic acid 3'-(Aminocarbonyl)-[1,1'-biphenyl]-3-yl ester |
| Purity: | ≥98% |
Broad spectrum cysteine reactive probe
| Alternate Names: | iodoacetamide alkyne |
| Chemical Name: | N-5-Hexyn-1-yl-2-iodoacetamide |
| Purity: | ≥97% |
Reversible TRPA1 channel blocker
| Chemical Name: | 4-(4-Chlorophenyl)-3-methyl-3-buten-2-one oxime |
| Purity: | ≥98% |
Selective TRPA1 activator
| Chemical Name: | (2E)-2-[7-Fluoro-1,2-dihydro-1-(2-methylpropyl)-2-oxo-3H-indol-3-ylidene]acetic acid |
| Purity: | ≥98% |
Potent and selective TRPA1 antagonist
| Chemical Name: | 1-[[3-[2-(4-Chlorophenyl)ethyl]-1,2,4-oxadiazol-5-yl]methyl]-1,7-dihydro-7-methyl-6H-purin-6-one |
| Purity: | ≥98% |
Potent and selective TRPA1 antagonist. Brain penetrant and orally bioavailable
| Chemical Name: | (1R,2R)-2-[(4-Fluorophenyl)amino]-1-(trifluoromethyl)cyclohexanol |
| Purity: | ≥98% |
| Reactivity: | Human, Mouse, Rat, Guinea Pig, Zebrafish |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, Flow, ICC/IF |
