Anti- Ipilimumab (Anti-Idiotype) Antibody Summary
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Detection of Ipilimumab by Western Blot. Western blot shows lysates of Cetuximab, Brentuximab, Teprotumumab, Aducanumab, and Ipilimumab. PVDF membrane was probed with 2 µg/mL of Mouse Anti-Anti- Ipilimumab (Anti-Idiotype) Monoclonal Antibody (Catalog # MAB10064) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF018). A specific band was detected for Ipilimumab at approximately 240 kDa (as indicated). This experiment was conducted under non-reducing conditions and using Immunoblot Buffer Group 1.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
The anti-Ipilimumab antibody is an anti-Idiotype antibody raised against and selected for the antigenic determinants of the variable region of Ipilimumab. The antibody has been tested against a broad range of other biosimilars to ensure specificity. This highly specialized anti-idiotypic antibody can be used in a variety of pharmacokinetic (PK) assay formats.
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