5-HT1D is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of 5-HT1D is mediated by G proteins that inhibit adenylate cyclase activity. There is an association between polymorphisms within the genes encoding 5-HT1D and 5-HT1B with anorexia nervosa (AN). mRNA concentrations of the 5-HT1D receptor and the transcription factors, NUDR and REST, were significantly increased in dorsal raphe nucleus-captured neurons of female major depressive disorder subjects.
Human 5-HT1D (NP_000855) VersaClone cDNA
R&D Systems | Catalog # RDC0285
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: 5-HT1D
Long Name
5-Hydroxytryptamine Receptor 1D
Alternate Names
5HT1D, HT1DA, HTR1D, HTR1DA, HTRL, RDC4
Gene Symbol
HTR1D
UniProt
Additional 5-HT1D Products
Product Documents for Human 5-HT1D (NP_000855) VersaClone cDNA
Certificate of Analysis
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Product Specific Notices for Human 5-HT1D (NP_000855) VersaClone cDNA
For research use only
Related Research Areas
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