Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 60402
View all Activin RIIB Primary Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Activin RIIB
Ser19-Thr134
Accession # Q13705

Specificity

Detects human Activin RIIB in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 5% cross-reactivity with recombinant human Activin RIIA is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for Human Activin RIIB Antibody

Application
Recommended Usage

Western Blot

1 µg/mL
Sample: Recombinant Human Activin RIIB Fc Chimera (Catalog # 339-RB)

Reviewed Applications

Read 1 review rated 5 using MAB3393 in the following applications:

Formulation, Preparation, and Storage

Purification

Protein A or G purified from ascites

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: Activin RIIB

Members of the TGF-beta superfamily exert their biological effects by binding to heteromeric complexes of a type I and a type II serine-threonine kinase receptor, both of which are essential for signal transduction. Activin receptor type IIB is a type II receptor that mediates multiple signals for transforming growth factor‑beta (TGF‑beta) family members, including Activin, Nodal, Bmp7, Gdf1, Gdf3, Myostatin (Gdf8), and Gdf11. Through alternative mRNA splicing, multiple ActR-IIB isoforms can also be generated. Human, mouse and rat activin RIIB share greater than 98% amino acid sequence homology.

Long Name

Activin Receptor IIB

Alternate Names

ActivinRIIB, ACVR2B

Entrez Gene IDs

93 (Human); 11481 (Mouse)

Gene Symbol

ACVR2B

UniProt

Q13705

Additional Activin RIIB Products

Product Documents for Human Activin RIIB Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Download SDS

Product Specific Notices for Human Activin RIIB Antibody

For research use only

Related Research Areas

Activin Family

Citations for Human Activin RIIB Antibody

Customer Reviews for Human Activin RIIB Antibody (1)

5 out of 5
1 Customer Rating
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  • Human Activin RIIB Antibody
    Name: Anonymous
    Application: ELISA
    Sample Tested: Human recombinant antibody
    Species: Human
    Verified Customer | Posted 04/07/2020
    Human Activin RIIB Antibody MAB3393

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