Human alpha-Synuclein Antibody

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Product Details
Citations (1)
Supplemental Products

Human alpha-Synuclein Antibody Summary

Species Reactivity
Detects human alpha -Synuclein in direct ELISAs and Western blots.
Monoclonal Mouse IgG1 Clone # 189105
Protein A or G purified from hybridoma culture supernatant
E. coli-derived recombinant human alpha -Synuclein
Accession # P37840
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.


Recommended Concentration
Western Blot
1 µg/mL
Recombinant Human alpha -Synuclein

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

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Preparation and Storage

Reconstitute at 0.5 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Size / Price
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: alpha-Synuclein

alpha -Synuclein is a cytoplasmic protein that is predominantly expressed in the central nervous system. It is a precursor of a minor peptide found in amyloid deposition that is a hallmark of Alzheimer's disease. Defects in alpha -Synuclein are associated with familial Parkinson's disease.

Entrez Gene IDs
6622 (Human); 20617 (Mouse); 29219 (Rat); 641350 (Porcine); 282857 (Bovine)
Alternate Names
alpha-Synuclein; I+/--synuclein; MGC110988; NACP; non A-beta component of AD amyloid; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; PARK1; PARK4; PD1; SNCA; synuclein alpha-140; synuclein, alpha (non A4 component of amyloid precursor); Synuclein-alpha; truncated alpha synuclein

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Citation for Human alpha-Synuclein Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. Extensive uptake of ?-synuclein oligomers in astrocytes results in sustained intracellular deposits and mitochondrial damage
    Authors: V Lindström, G Gustafsson, LH Sanders, EH Howlett, J Sigvardson, A Kasrayan, M Ingelsson, J Bergström, A Erlandsson
    Mol. Cell. Neurosci., 2017;0(0):.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: ELISA Development (Capture)


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Isotype Controls

Reconstitution Buffers

Secondary Antibodies

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