Human CD4 PerCP-conjugated Antibody
Human CD4 PerCP-conjugated Antibody Summary
Extracellular Domain
Accession # P01730
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data
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Detection of CD4 in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with (A) Mouse Anti-Human CD4 PerCP-conjugated Monoclonal Antibody (Catalog # FAB3791C) or (B) Mouse IgG2APerCP Isotype Control (Catalog # IC003C) and Mouse Anti-Human CD3e APC-conjugated Monoclonal Antibody (Catalog # FAB100A). View our protocol for Staining Membrane-associated Proteins.
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Preparation and Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: CD4
CD4 is a type I membrane glycoprotein belonging to the immunoglobulin superfamily. It is expressed predominantly on thymocytes and a subset of mature T lymphocytes. CD4 functions in collaboration with the T cell receptor in the recognition of peptide antigens that are presented by class II major histocompatibility complexes. CD4 also has been shown to be a coreceptor of HIV entry and specifically binds gp120, the external envelope glycoprotein of HIV.
Product Datasheets
Citations for Human CD4 PerCP-conjugated Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 3
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Lower CXCR3 expression in both patients with neovascular AMD and advanced stages of chronic myeloproliferative blood cancers
Authors: C Liisborg, V Skov, L Kjær, HC Hasselbalc, T Lykke Søre
PLoS ONE, 2022;17(6):e0269960.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Enlarged memory T-cell pool and enhanced Th1-type responses in chronic myeloid leukemia patients who have successfully discontinued IFN-alpha monotherapy.
Authors: Ilander M, Kreutzman A, Rohon P, Melo T, Faber E, Porkka K, Vakkila J, Mustjoki S
PLoS ONE, 2014;9(1):e87794.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Cytotoxicity of CD56(bright) NK cells towards autologous activated CD4+ T cells is mediated through NKG2D, LFA-1 and TRAIL and dampened via CD94/NKG2A.
Authors: Nielsen N, Odum N, Urso B, Lanier LL, Spee P
PLoS ONE, 2012;7(2):e31959.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry
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