Reacts specifically with human and non-human cells expressing human CXCR4 (fusin) as detected by flow cytometry. It will also react with cells expressing feline CXCR4 but not rat CXCR4. This antibody does not cross-react with other chemokine receptors.
Monoclonal Mouse IgG2B Clone # 44717
Protein A or G purified from ascites
Mouse 3T3 cells transfected with human CXCR4
Supplied in a saline solution containing BSA and Sodium Azide.
Detection of CXCR4 in Human Blood Lymphocytes by Flow Cytometry.
Human peripheral blood lymphocytes were stained with Mouse Anti-Human CXCR4 Biotinylated Monoclonal Antibody (Catalog # FAB173B) followed by Streptavidin-Phycoerythrin (Catalog # F0040) and Mouse Anti-Human CD19 APC‑conjugated Monoclonal Antibody (Catalog # FAB4867A). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Do not freeze.
12 months from date of receipt, 2 to 8 °C as supplied.
CXCR4 is a G-protein-linked seven transmembrane spanning receptor that
binds stromal cell-derived factor-1 (SDF-1). CXCR4 acts as a co-factor
for T-cell tropic HIV-1 and -2 viral entry into cells.
R&D Systems personnel manually curate a database that contains references using R&D Systems products.
The data collected includes not only links to publications in PubMed,
but also provides information about sample types, species, and experimental conditions.
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