Human Integrin alpha 4/CD49d Antibody

Name: Human Integrin alpha 4/CD49d Antibody
Brand: R&D Systems
SKU: MAB13541
Price: 399 USD
Availability: InStock

R&D Systems | Catalog # MAB13541

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Product Specifications
Applications
Preparation & Storage
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Background
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Research Areas

Key Product Details

Species Reactivity

Human

Applications

ELISA

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG₁ Clone # 599904

View all Integrin alpha 4/CD49d Primary Antibodies »

Product Specifications

Immunogen

Chinese hamster ovary cell line CHO-derived recombinant human Integrin alpha 4/CD49d
Tyr34-Gln970 (Arg591Leu & Arg878Gln)
Accession # P13612

Specificity

Detects human Integrin alpha 4/CD49d in direct ELISA. In a sandwich immunoassay, this antibody detects the human Integrin alpha 4 beta 1 heterodimer when used with the suggested detection antibody, Mouse Anti-Human Integrin beta 1 (Catalog # MAB17784).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁

Applications for Human Integrin alpha 4/CD49d Antibody

Application

Recommended Usage

ELISA

This antibody functions as an ELISA capture antibody the human Integrin alpha 4 beta 1 heterodimer when paired with Mouse Anti-Human Integrin beta 1 Monoclonal Antibody (Catalog # MAB17784).

This product is intended for assay development on various assay platforms requiring antibody pairs.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Background: Integrin alpha 4/CD49d

The alpha 4 subunit, also known as CD49d and VLA-4 alpha subunit, forms heterodimers with Integrin beta 1 (CD29) or beta 7. Integrins alpha 4 beta 1 and alpha 4 beta 7 are receptors for fibronectin and VCAM. Integrin alpha 4 beta 1 also binds the mucosal addressin cell adhesion molecule (MAdCAM-1).