Human/Mouse Kirrel2/NEPH3 Antibody

Catalog # Availability Size / Price Qty
MAB2564
MAB2564-SP
Product Details
Citations (1)
FAQs
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Human/Mouse Kirrel2/NEPH3 Antibody Summary

Species Reactivity
Human, Mouse
Specificity
Detects human and mouse Kirrel2/NEPH3 in direct ELISAs and Western blots.
Source
Monoclonal Mouse IgG1 Clone # 318311
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Mouse myeloma cell line NS0-derived recombinant human Kirrel2
Gly21-Arg503
Accession # Q6UWL6
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
1 µg/mL
Recombinant Human Kirrel2 (Catalog # 2564-K2)
Recombinant Mouse Kirrel2 (Catalog # 2930-K2)
under non-reducing conditions only

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Availability
Size / Price
Qty
RB01
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Kirrel2/NEPH3

Kirrel2, also known as nephrin-like 3, nephrin-like gene 1 and filtrin, is a type I transmembrane protein belonging to the immunoglobulin superfamily. By alternative splicing, at least 5 isoforms that differ in their extracellular and/or intracellular regions have been described. Kirrel2 is expressed in the pancreas, lymph nodes, kidney glomerulus, as well as brain. The extracellular domains of human and mouse Kirrel2 share 86% amino acid sequence identity.

Long Name
Kin of Irregular Chiasm-like 2, Splice Variant A
Entrez Gene IDs
84063 (Human); 243911 (Mouse)
Alternate Names
DKFZp564A1164; Filtrin; FILTRINkin of IRRE-like protein 2; kin of IRRE like 2 (Drosophila); Kin of irregular chiasm-like protein 2; Kirrel2; MGC15718; NEPH3; NEPH3Nephrin-like protein 3; nephrin-like 3; nephrin-like gene 1; NLG1; NLG1kin of irregular chiasm-like 2

Product Datasheets

Citation for Human/Mouse Kirrel2/NEPH3 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. Retinoic acid selectively inhibits death of basal vomeronasal neurons during late stage of neural circuit formation.
    Authors: Hornberg M, Gussing F, Berghard A, Bohm S
    J. Neurochem., 2009;110(4):1263-75.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC Frozen

FAQs

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Isotype Controls

Mouse IgG1 Isotype Control

Ctrl

Reconstitution Buffers

Secondary Antibodies

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