Human Serpin A8/Angiotensinogen Antibody
Human Serpin A8/Angiotensinogen Antibody Summary
Accession # P01019
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Serpin A8/Angiotensinogen
Angiotensinogen, a member of the serpin family (Serpin A8), is synthesized in liver and cleaved by renin to produce angiotensin I. This is further processed by angiotensin converting enzyme (ACE) to yield angiotensin II, a key blood pressure regulator. The amino acid sequence of human AGT is 99%, 68%, 64%, and 61% identical to that of chimpanzee, canine, rat, and mouse.
Citations for Human Serpin A8/Angiotensinogen Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
Citations: Showing 1 - 2
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Improved Assay for Quantifying a Redox Form of Angiotensinogen as a Biomarker for Pre-Eclampsia: A Case-Control Study.
Authors: Rahgozar S, Amirian T, Qi M, Shahshahan Z, Entezar-E-Ghaem M, Ghasemi Tehrani H, Miroliaei M, Krilis S, Giannakopoulos B
PLoS ONE, 2015;10(8):e0135905.
Sample Types: Plasma
Applications: ELISA Development (Capture)
Increased urinary Angiotensinogen/Creatinine (AGT/Cr) ratio may be associated with reduced renal function in autosomal dominant polycystic kidney disease patients.
Authors: Park H, Kang A, Jang J, Kim H, Han M, Oh K, Kim S, Noh J, Cheong H, Hwang Y, Ahn C
BMC Nephrol, 2015;16(0):86.
Sample Types: Whole Tissue
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