Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry

Label

NL493 (Excitation = 493 nm, Emission = 514 nm)

Antibody Source

Polyclonal Goat IgG
View all SOX2 Primary Antibodies »

Product Specifications

Specificity

Detects human SOX2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human SOX17 is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Human SOX2 NorthernLights™ NL493-conjugated Antibody

Application
Recommended Usage

Immunocytochemistry

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.

Background: SOX2

SOX2 belongs to the SOX (SRY-like HMG box) family of transcription factors with diverse roles in development. SOX2 functions in specifying the first three lineages present at implantation and in regulating proliferation and differentiation in the developing peripheral nervous system (1-5).

References

  1. Graham, V. et al. (2003) Neuron 39:749.
  2. Avilion, A.A. et al. (2003) Genes Dev. 17:126.
  3. Kishi, M. et al. (2000) Development 127:791.
  4. Yuan, H. et al. (1995) Genes Dev. 9:2635.
  5. Uwanogho, D. et al. (1995) Mech. Dev. 49:23.
  6. Stevanovic, M. (2003) Mol. Biol. Rep. 30:127.

Long Name

Transcription Factor SOX2

Alternate Names

ANOP3, MCOPS3, MGC2413, SRY (sex determining region Y)-box 2, SRY-related HMG-box gene 2, transcription factor SOX2, transcription factor SOX-2

Entrez Gene IDs

6657 (Human)

Gene Symbol

SOX2

UniProt

P48431

Additional SOX2 Products

Product Documents for Human SOX2 NorthernLights™ NL493-conjugated Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human SOX2 NorthernLights™ NL493-conjugated Antibody

For research use only

Citations for Human SOX2 NorthernLights™ NL493-conjugated Antibody

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